Review

October 2, 2024


Roles of X-box binding protein 1 in liver pathogenesis
Jihoon Tak, Yun Seok Kim, Sang Geon Kim
Clin Mol Hepatol. 2025;31(1):1-31.

Review

October 2, 2024


Sinusoidal communication in chronic liver disease
Albert Gibert-Ramos, María Andrés-Rozas, Raül Pastó, et al.
Clin Mol Hepatol. 2025;31(1):32-55.

Review

October 21, 2024


Bioactive metabolites: A clue to the link between MASLD and CKD?
Wen-Ying Chen, Jia-Hui Zhang, Li-Li Chen, et al.
Clin Mol Hepatol. 2025;31(1):56-73.

Review

October 23, 2024


Long-term outcomes and risk modifiers of metabolic dysfunction-associated steatotic liver disease between lean and non-lean populations
Pojsakorn Danpanichkul, Kanokphong Suparan, Vitchapong Prasitsumrit, et al.
Clin Mol Hepatol. 2025;31(1):74-89.

Review

November 11, 2024


Hard-to-treat autoimmune hepatitis and primary biliary cholangitis: The dawn of a new era of pharmacological treatment
Atsumasa Komori, Yuki Kugiyama
Clin Mol Hepatol. 2025;31(1):90-104.

Original Article

July 11, 2024


Carvedilol to prevent hepatic decompensation of cirrhosis in patients with clinically significant portal hypertension stratified by new non-invasive model (CHESS2306)
Chuan Liu, Hong You, Qing-Lei Zeng, et al.
Clin Mol Hepatol. 2025;31(1):105-118.

Original Article

September 24, 2024


Safety and efficacy of HK-660S in patients with primary sclerosing cholangitis: A randomized double-blind phase 2a trial
Woo Hyun Paik, Joo Kyung Park, Moon Jae Chung, et al.
Clin Mol Hepatol. 2025;31(1):119-130.

Original Article

October 2, 2024


Optimal tacrolimus levels for reducing CKD risk and the impact of intrapatient variability on CKD and ESRD development following liver transplantation
Soon Kyu Lee, Ho Joong Choi, Young Kyoung You, et al.
Clin Mol Hepatol. 2025;31(1):131-146.

Original Article

October 2, 2024


USP29 alleviates the progression of MASLD by stabilizing ACSL5 through K48 deubiquitination
Sha Hu, Zhouxiang Wang, Kun Zhu, et al.
Clin Mol Hepatol. 2025;31(1):147-165.

Original Article

October 4, 2024


Self-testing strategy to eliminate hepatitis C as per World Health Organization’s goal: Analysis of disease burden and cost-effectiveness
Gyeongseon Shin, Beom Kyung Kim, SeungJin Bae, et al.
Clin Mol Hepatol. 2025;31(1):166-178.

Original Article

October 11, 2024


Metabolic dysfunction-associated steatotic liver disease exhibits sex-specific microbial heterogeneity within intestinal compartments
Carlos Jose Pirola, Maria Silvina Landa, Mariano Schuman, et al.
Clin Mol Hepatol. 2025;31(1):179-195.

Original Article

October 15, 2024


Aberrant fragmentomic features of circulating cell-free mitochondrial DNA enable early detection and prognosis prediction of hepatocellular carcinoma
Yang Liu, Fan Peng, Siyuan Wang, et al.
Clin Mol Hepatol. 2025;31(1):196-212.

Original Article

October 17, 2024


Antiviral therapy for chronic hepatitis B with mildly elevated aminotransferase: A rollover study from the TORCH-B trial
Yao-Chun Hsu, Chi-Yi Chen, Cheng-Hao Tseng, et al.
Clin Mol Hepatol. 2025;31(1):213-226.

Original Article

November 14, 2024


Bariatric surgery reduces long-term mortality in patients with metabolic dysfunction-associated steatotic liver disease and cirrhosis
Nicholas A. Rouillard, Scott D. Barnett, Xinrong Zhang, et al.
Clin Mol Hepatol. 2025;31(1):227-239.

Original Article

November 21, 2024


Insertion of a transjugular intrahepatic portosystemic shunt leads to sustained reversal of systemic inflammation in patients with decompensated liver cirrhosis
Anja Tiede, Lena Stockhoff, Zhaoli Liu, et al.
Clin Mol Hepatol. 2025;31(1):240-255.


Articles in E-pub version are posted online ahead of regular printed publication.

Reply to Correspondence
Reply to correspondence on “GOLM1 promotes cholesterol gallstone formation via ABCG5-mediated cholesterol efflux in MASH livers”
Yoon-su Ha, Won Kim, Seung-Jin Kim
Received February 4, 2025  Accepted February 12, 2025  
View: 62   Download: 1
Correspondence
Addressing the Burden of Steatotic Liver Disease: The Role of Transient Elastography: Correspondence to editorial on “Vibration-controlled transient elastography in shaping the epidemiology and management of steatotic liver disease”
Donghee Kim, Pojsakorn Danpanichkul, Karn Wijarnpreecha, George Cholankeril, Rohit Loomba, Aijaz Ahmed
Received February 4, 2025  Accepted February 12, 2025  
View: 58   Download: 5
GOLM1 and Bile Acid Synthesis: Correspondence to the Editorial “Bridging the Gap: The GOLM1-OPN-ABCG5 Axis in MASH and Gallstone Disease”
Yi-Tong Li, Wei-Qing Shao, Zhen-Mei Chen, Jing Lin, Jin-Hong Chen
Received February 3, 2025  Accepted February 12, 2025  
View: 52   Download: 5
Editorial
Is AMA M2 a Useful Serologic Test for Screening High-Risk Patients for PBC?
Nae-Yun Heo
Received February 3, 2025  Accepted February 11, 2025  
View: 42   Download: 1
Risk stratification for hepatocellular carcinoma in metabolic dysfunction-associated steatotic liver disease
Ho Soo Chun, Minjong Lee
Received February 2, 2025  Accepted February 7, 2025  
View: 87   Download: 6
Tetraspan(in)-mediated immune regulation in hepatocellular carcinoma
Seo Hee Jin, Dong Joo Kim, Jung Weon Lee
Received January 31, 2025  Accepted February 7, 2025  
View: 119   Download: 23
Correspondence
TIPS insertion and systemic inflammation: Is it ever too late to lower portal pressure?
Anja Tiede, Benjamin Maasoumy
Received February 6, 2025  Accepted February 6, 2025  
View: 80   Download: 5
Editorial
Burden of alcohol use disorder, alcohol-related liver disease, and alcohol-related liver cancer
Youxin Wang, Noriko Oza, Jazleen Leo, Ashok Choudhury, Daniel Q. Huang
Received February 5, 2025  Accepted February 6, 2025  
View: 210   Download: 14
TM4SF1 - A new immune target for treatment of hepatocellular carcinoma
Chen Rui YUAN, Terence Kin Wah LEE
Received January 29, 2025  Accepted February 6, 2025  
View: 106   Download: 10
Original Article
Radiogenomics of intrahepatic cholangiocarcinoma predicts immunochemotherapy response and identifies therapeutic target
Gu-Wei Ji, Zheng-Gang Xu, Shuo-Chen Liu, Shu-Ya Cao, Chen-Yu Jiao, Ming Lu, Biao Zhang, Yue Yang, Qing Xu, Xiao-Feng Wu, Ke Wang, Yong-Xiang Xia, Xiang-Cheng Li, Xue-Hao Wang
Received October 9, 2024  Accepted February 7, 2025  
View: 1004   Download: 48
Letter to the Editor
Letter to the editor on “Bariatric surgery reduces long-term mortality in patients with metabolic dysfunction-associated steatotic liver disease and cirrhosis”
Chi-Kuei Hsu, Po-Yu Huang, Chih-Cheng Lai
Received January 19, 2025  Accepted February 4, 2025  
View: 116   Download: 7
Snapshot
Interventions Targeting the Gut-Liver Axis: A Potential Treatment Strategy for MASLD
Pingping Jin, Xinyi Lu, Daozhen Chen, Yu Chen
Received December 2, 2024  Accepted February 4, 2025  
View: 152   Download: 25
Original Article
GULP1 as a Novel Diagnostic and Predictive Biomarker in Hepatocellular Carcinoma
Hyung Seok Kim, Jung Hwan Yoon, Ji Yi Choi, Moon Gyeong Yoon, Geum Ok Baek, Minji Kang, Se Ha Jang, Won Park, Yunjin Go, Jestlin Tianthing Ng, Suk Woo Nam, Jee-Yeong Jeong, Ji Eun Han, Hyo Jung Cho, Su Bin Lim, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun
Received November 19, 2024  Accepted February 4, 2025  
View: 511   Download: 140
Correspondence
Correspondence to Editorial on “Targeting TM4SF1 to overcome immunotherapy resistance in hepatocellular carcinoma”
Weifeng Zeng, Furong Liu, Yachong Liu, Zhanguo Zhang
Received January 22, 2025  Accepted February 1, 2025  
View: 134   Download: 10
Review
Deciphering adenosine signaling in hepatocellular carcinoma: pathways, prognostic models, and therapeutic implications
Huihai Yang, Martina Mang Leng Lei, Longfei Xie, Yinuo Shou, Terence Kin Wah Lee
Received November 26, 2024  Accepted February 2, 2025  
View: 354   Download: 43
Original Article
Direct-acting antiviral therapy for patients with HCV-related hepatocellular carcinoma: A nationwide cohort study
Shou-Wu Lee, Sheng-Shun Yang, Pei-Chien Tsai, Chung-Feng Huang, Chi-Yi Chen, Chao-Hung Hung, Chien-Hung Chen, Chi-Ming Tai, Pin-Nan Cheng, Hsing-Tao Kuo, Kuo-Chih Tseng, Lein-Ray Mo, Ching-Chu Lo, Yi-Hsiang Huang, Han-Chieh Lin, Pei-Lun Lee, Ming-Jong Bair, Te-Sheng Chang, Chun-Yen Lin, Szu-Jen Wang, Tsai-Yuan Hsieh, Tzeng-Hue Yang, Cheng-Yuan Peng, Chi-Chieh Yang, Lee-Won Chong, Chien-Wei Huang, Chih-Wen Lin, Cheng-Hsin Chu, Ming-Chang Tsai, Jia-Horng Kao, Chun-Jen Liu, Wan-Long Chuang, Teng-Yu Lee, Ming- Lung Yu, on behalf of TACR investigators
Received November 10, 2024  Accepted January 16, 2025  
View: 392   Download: 35
FIB-4plus Score: A novel machine learning-based tool for screening high-risk varices in compensated cirrhosis (CHESS2004): An international multicenter study
Bingtian Dong, Ruiling He, Shenghong Ju, Yuping Chen, Ivica Grgurevic, Jianzhong Ma, Ying Guo, Huizhen Fan, Qiang Yan, Chuan Liu, Huixiong Xu, Anita Madir, Kristian Podrug, Jia Wang, Linxue Qian, Zhengzi Geng, Shanghao Liu, Tao Ren, Guo Zhang, Kun Wang, Meiqin Su, Fei Chen, Sumei Ma, Liting Zhang, Zhaowei Tong, Yonghe Zhou, Xin Li, Fanbin He, Hui Huan, Wenjuan Wang, Yunxiao Liang, Juan Tang, Fang Ai, Tingyu Wang, Liyun Zheng, Zhongwei Zhao, Jiansong Ji, Wei Liu, Jiaojiao Xu, Bo Liu, Xuemei Wang, Yao Zhang, Qiong Yan, Hui Liu, Xiaomei Chen, Shuhua Zhang, Yihua Wang, Yang Liu, Li Yin, Yanni Liu, Yanqing Huang, Li Bian, Ping An, Xin Zhang, Shaoting Zhang, Jinhua Shao, Xiangman Zhang, Wei Rao, Chaoxue Zhang, Dietrich Christoph Frank, Won Kim, Xiaolong Qi
Received October 10, 2024  Accepted February 3, 2025  
View: 518   Download: 50
GDH1-dependent α-ketoglutarate promotes HBV transcription by modulating histone methylations on the cccDNA minichromosome
Sheng-Tao Cheng, Wei-Xian Chen, Hai-Jun Deng, Xin He, Hui Zhang, Ming Tan, Hai-Bo Yu, Zhen-Zhen Zhang, Ji-Hua Ren, Min-Li Yang, Da-Peng Zhang, Zhi-Hong Li, Juan Chen
Received August 21, 2024  Accepted January 28, 2025  
View: 301   Download: 54
Baveno VI-SSM stratifies the risk of portal hypertension-related events in patients with HBV-related cirrhosis
Haiyu Wang, Weihao Liang, Ling Zhou, Jiankang Song, Biao Wen, Qiaoping Wu, Yuanjian Zhang, Xiaofeng Zhang, Haoran Ke, Yujun Tang, Fuyuan Zhou, Youfu Zhu, Weiqun Wen, Zhihua Liu, Yali Ji, Qintao Lai, Qinjun He, Wenfan Luo, Tingting Qi, Miaoxia Liu, Xiaoqin Lan, Yongpeng Chen, Ranran Xi, Junting Wan, Lin Dai, Yuan Li, Jinjun Chen
Received July 29, 2024  Accepted January 29, 2025  
View: 221   Download: 21
Reply to Correspondence
Reply to correspondence to editorial on “Bariatric Surgery Reduces Long-Term Mortality in Patients with MASLD and Cirrhosis”
Jing Zeng, Jian-Gao Fan
Received January 19, 2025  Accepted January 24, 2025  
View: 156   Download: 9
Correspondence
Correspondence to editorial on “GOLM1 promotes cholesterol gallstone formation via ABCG5-mediated cholesterol efflux in MASH livers”
Yi-Tong Li, Wei-Qing Shao, Zhen-Mei Chen, Jing Lin, Jin-Hong Chen
Received January 21, 2025  Accepted January 23, 2025  
View: 152   Download: 21
Editorial
Intrapatient variability of tacrolimus trough level may be not the cause, but an indirect parameter of comorbidities
Jongman Kim
Received January 20, 2025  Accepted January 23, 2025  
View: 154   Download: 20
Genetic Insights into Sarcomatoid Hepatocellular Carcinoma: Critical Role of ARID2 in Pathogenesis and Immune Feature
Naoshi Nishida
Received January 19, 2025  Accepted January 23, 2025  
View: 163   Download: 13
Review
Unveiling the Intratumor Microbiome in Liver Cancer: Current Insights and Prospective Applications
Xindi Ke, Shangze Jiang, Qiaoxin Wei, Minghao Sun, Hang Sun, Mingchang Pang, Mei Liu, Lejia Sun, Huayu Yang, Yilei Mao
Received November 19, 2024  Accepted January 20, 2025  
View: 388   Download: 46
Update on the treatment navigation for functional cure of chronic hepatitis B: expert consensus 2.0
Di Wu, Jia-Horng Kao, Teerha Piratvisuth, Xiaojing Wang, Patrick T.F. Kennedy, Motoyuki Otsuka, Sang Hoon Ahn, Yasuhito Tanaka, Guiqiang Wang, Zhenghong Yuan, Wenhui Li, Young-Suk Lim, Junqi Niu, Fengmin Lu, Wenhong Zhang, Zhiliang Gao, Apichat Kaewdech, Meifang Han, Weiming Yan, Hong Ren, Peng Hu, Sainan Shu, Paul Yien Kwo, Fu-sheng Wang, Man-Fung Yuen, Qin Ning
Received September 9, 2024  Accepted January 21, 2025  
View: 762   Download: 154
Original Article
Modulation of PRL-1 within placental MSCs instigates the transition between EMT and MET subsequent to hepatic fibrosis
Jae Yeon Kim, Hyeri Park, Soo Young Park, Se Ho Kim, Ja Yun Lim, Ki Seog Lee, Si Hyun Bae, Gi Jin Kim
Received September 12, 2024  Accepted January 20, 2025  
View: 3595   Download: 673
Letter to the Editor
What is new in the 2024 Chinese guidelines for fatty liver disease?
Rui-Xu Yang, Vincent Wai-Sun Wong, Jian-Gao Fan
Received December 27, 2024  Accepted January 18, 2025  
View: 201   Download: 21
Original Article
Switching to Besifovir in Patients with Chronic Hepatitis B Receiving Tenofovir Disoproxil Fumarate: A Randomized Trial
Hyung Joon Yim, Yeon Seok Seo, Ji Hoon Kim, Won Kim, Young Kul Jung, Jae Young Jang, Sae Hwan Lee, Yun Soo Kim, Chang Wook Kim, Hyoung Su Kim, Jae-Jun Shim, Eun-Young Cho, In Hee Kim, Byung Seok Lee, Jeong-Hoon Lee, Byung Seok Kim, Jeong Won Jang, Hyun Woong Lee, Jung Hyun Kwon, Moon Young Kim, Do Seon Song, Jung Gil Park, Yoon Seok Lee, Eileen L. Yoon, Han Ah Lee, Seong Hee Kang, Jin Mo Yang
Received September 19, 2024  Accepted January 16, 2025  
View: 483   Download: 37
Editorial
Unraveling the role of GOLM1-OPN-ABCG5 axis in MASH: Editorial on “GOLM1 promotes cholesterol gallstone formation via ABCG5-mediated cholesterol efflux in MASH livers”
Yoon-su Ha, Won Kim, Seung-Jin Kim
Received January 10, 2025  Accepted January 13, 2025  
View: 336   Download: 25
Reply to Correspondence
Reply to correspondence on “Circulating cell-free mitochondrial DNA for diagnosing hepatocellular carcinoma and assessing prognosis”
Hyuk Soo Eun
Received January 10, 2025  Accepted January 12, 2025  
View: 258   Download: 10
Editorial
Targeting TM4SF1 to overcome immunotherapy resistance in hepatocellular carcinoma
Valerie Chew
Received January 9, 2025  Accepted January 12, 2025  
View: 250   Download: 25
Original Article
Exploring Methylation Signatures for High De Novo Recurrence Risk in Hepatocellular carcinoma
Da-Won Kim, Jin Hyun Park, Suk Kyun Hong, Min-Hyeok Jung, Ji-One Pyeon, Jin-Young Lee, Kyung-Suk Suh, Nam-Joon Yi, YoungRok Choi, Kwang-Woong Lee, Young-Joon Kim
Received October 11, 2024  Accepted January 7, 2025  
View: 254   Download: 26
Correspondence
Correspondence to Editorial on “Bariatric Surgery Reduces Long-Term Mortality in Patients with Metabolic Dysfunction-Associated Steatotic Liver Disease and Cirrhosis”
Nicholas A. Rouillard, Linda Henry, Mindie H. Nguyen
Received January 1, 2025  Accepted January 4, 2025  
View: 256   Download: 13
Letter to the Editor
Tacrolimus Levels and Variability in CKD and ESRD Risk Post-Liver Transplant
Rui Shi, Minghua Wang
Received December 21, 2024  Accepted January 6, 2025  
View: 251   Download: 16
Original Article
Adverse impact of metabolic dysfunction on fibrosis regression following direct-acting antiviral therapy: A multicenter study for chronic hepatitis C
Tom Ryu, Young Chang, Soung Won Jeong, Jeong-Ju Yoo, Sae Hwan Lee, Sang Gyune Kim, Young Seok Kim, Hong Soo Kim, Seung Up Kim, Jae Young Jang
Received October 12, 2024  Accepted January 5, 2025  
View: 354   Download: 40
Global Epidemiology of Alcohol-Related Liver Disease, Liver Cancer, and Alcohol Use Disorder, 2000–2021
Pojsakorn Danpanichkul, Luis Antonio Díaz, Kanokphong Suparan, Primrose Tothanarungroj, Supapitch Sirimangklanurak, Thanida Auttapracha, Hanna L. Blaney, Banthoon Sukphutanan, Yanfang Pang, Siwanart Kongarin, Francisco Idalsoaga, Eduardo Fuentes-López, Lorenzo Leggio, Mazen Noureddin, Trenton M. White, Alexandre Louvet, Philippe Mathurin, Rohit Loomba, Patrick S. Kamath, Jürgen Rehm, Jeffrey V. Lazarus, Karn Wijarnpreecha, Juan Pablo Arab
Received September 26, 2024  Accepted January 3, 2025  
View: 1135   Download: 124  Crossref: 1
Correspondence
Correspondence on Editorial regarding “Usefulness of circulating cell-free mitochondrial DNA on hepatocellular carcinoma diagnosis and prognosis assessment”
Yang Liu, Fan Peng, Siyuan Wang, Jinliang Xing
Received December 30, 2024  Accepted January 1, 2025  
View: 213   Download: 19
Editorial
Treating systemic inflammation by transjugular intrahepatic portosystemic shunt
Georg Semmler, Lorenz Balcar, Mattias Mandorfer
Received January 29, 2024  Accepted January 1, 2025  
View: 251   Download: 27
Correspondence
Reply to “MAFLD or MASLD: Which Better Represents the Prognosis of the Steatotic Liver Population”
Seogsong Jeong, Won Kim, Sang Min Park
Received December 26, 2024  Accepted January 2, 2025  
View: 368   Download: 15
Reply to “Evolutionary changes in metabolic dysfunction-associated steatotic liver disease and risk of hepatocellular carcinoma”
Seogsong Jeong, Won Kim, Sang Min Park
Received December 23, 2024  Accepted January 2, 2025  
View: 332   Download: 13
Original Article
High SAFE scores predict hepatocellular carcinoma in viral and non-viral hepatitis and metabolic dysfunction associated steatotic liver disease
Tung-Hung Su, Sheng-Shun Yang, Mei-Hsuan Lee, Wei-Yu Kao, Shang-Chin Huang, Fen-Fang Chen, Francis SK Poon, Lung-Wen Tsai, Yi-Ting Chen, Che Lin, Weichung Wang, W Ray Kim, Jia-Horng Kao
Received September 21, 2024  Accepted January 1, 2025  
View: 716   Download: 62
Male preference for TERT alterations and HBV integration in young-age HBV-related HCC: implications for sex disparity
Jin Seoub Kim, Hye Seon Kim, Kwon Yong Tak, Ji Won Han, Heechul Nam, Pil Soo Sung, Sung Won Lee, Jung Hyun Kwon, Si Hyun Bae, Jong Young Choi, Seung Kew Yoon, Jeong Won Jang
Received July 10, 2024  Accepted December 30, 2024  
View: 503   Download: 44
Correspondence
Age serves as the silent architect of FIB-4's precision in unveiling advanced hepatic fibrosis in MASLD with T2DM
Ji Won Han, Dae Won Jun
Received December 22, 2024  Accepted December 26, 2024  
View: 241   Download: 19
Letter to the Editor
Current Burden of MASLD, MetALD, and Hepatic Fibrosis among US Adults with Prediabetes and Diabetes, 2017-2023
Donghee Kim, Rohit Loomba, Aijaz Ahmed
Received December 20, 2024  Accepted December 29, 2024  
View: 685   Download: 90
Original Article
Targeting TM4SF1 promotes tumor senescence enhancing CD8+ T cell cytotoxic function in hepatocellular carcinoma
Weifeng Zeng, Furong Liu, Yachong Liu, Ze Zhang, Haofan Hu, Shangwu Ning, Hongwei Zhang, Xiaoping Chen, Zhibin Liao, Zhanguo Zhang
Received October 28, 2024  Accepted December 26, 2024  
View: 886   Download: 141
Prediction of primary biliary cholangitis among health check-up population with anti-mitochondrial M2 antibody positive
Haolong Li, Song Liu, Xu Wang, Xinxin Feng, Siyu Wang, Yanli Zhang, Fengchun Zhang, Li Wang, Tengda Xu, Yongzhe Li
Received June 3, 2024  Accepted December 25, 2024  
View: 428   Download: 53
Editorial
Circulating cell-free mitochondrial DNA for diagnosing hepatocellular carcinoma and assessing prognosis
Hyuk soo Eun
Received December 15, 2024  Accepted December 20, 2024  
View: 307   Download: 26
Vibration-Controlled Transient Elastography in Shaping the Epidemiology and Management of Steatotic Liver Disease
Xiao-Dong Zhou, Terry Cheuk-Fung Yip, Daniel Q Huang, Mark Dhinesh Muthiah, Mazen Noureddin, Ming-Hua Zheng
Received December 14, 2024  Accepted December 20, 2024  
View: 608   Download: 35
Review
Liver organoids: Current advances and future applications for hepatology
Yohan Kim, Minseok Kang, Michael Girma Mamo, Michael Adisasmita, Meritxell Huch, Dongho Choi
Received November 19, 2024  Accepted December 24, 2024  
View: 906   Download: 156
Letter to the Editor
MAFLD or MASLD: Which Better Represents the Prognosis of the Steatotic Liver Population
Ying Wang, Shengfeng Wang, Xiude Fan, Jiajun Zhao, Yongfeng Song
Received November 8, 2024  Accepted December 24, 2024  
View: 548   Download: 53  Crossref: 1
Review
Hepatocellular carcinoma: updates on epidemiology, surveillance, diagnosis and treatment
Soo Young Hwang, Pojsakorn Danpanichkul, Vatche Agopian, Neil Mehta, Neehar D. Parikh, Ghassan K. Abou-Alfa, Amit G. Singal, Ju Dong Yang
Received September 22, 2024  Accepted December 20, 2024  
View: 2078   Download: 423  Crossref: 1
Original Article
Longitudinal profile of plasma pregenomic RNA in patients with chronic hepatitis B infection on long-term nucleoside analogues and its interaction with clinical parameters
Lung-Yi Mak, Mark Anderson, Michael Stec, Matthew Shing-Hin Chung, Danny Ka-Ho Wong, Rex Wan-Hin Hui, Wai-Kay Seto, Gavin Cloherty, Man-Fung Yuen
Received August 27, 2024  Accepted December 21, 2024  
View: 508   Download: 49
Correspondence
Expanding Treatment Eligibility for Chronic Hepatitis B: Balancing Benefits, Limitations, and Healthcare Access
Yao-Chun Hsu, Chi-Yi Chen, Jaw-Town Lin
Received December 16, 2024  Accepted December 20, 2024  
View: 265   Download: 12
Original Article
MARC1 downregulation reduces hepatocyte lipid content by increasing beta-oxidation
Ester Ciociola, Tanmoy Dutta, Kavitha Sasidharan, Lohitesh Kovooru, Francesca R. Noto, Grazia Pennisi, Salvatore Petta, Angela Mirarchi, Samantha Maurotti, Bernardette Scopacasa, Luca Tirinato, Patrizio Candeloro, Marcus Henricsson, Daniel Lindén, Oveis Jamialahmadi, Arturo Pujia, Rosellina M. Mancina, Stefano Romeo
Received August 13, 2024  Accepted December 20, 2024  
View: 1010   Download: 187
Editorial
A leap in the dark: Bariatric surgery for treatment of metabolic dysfunction-associated steatotic liver disease related cirrhosis
Jing Zeng, Jian-Gao Fan
Received December 5, 2024  Accepted December 14, 2024  
View: 386   Download: 28
Letter to the Editor
Comment on: Evolutionary changes in metabolic dysfunction-associated steatotic liver disease and risk of hepatocellular carcinoma
Hai Xu, Yong Zhou, Huikun Wu
Received December 2, 2024  Accepted December 16, 2024  
View: 403   Download: 12
Global Inequality in the Burden of Hepatitis B From 1990 to 2021: Findings From the Global Burden of Disease Study 2021
Chunlong Liu, Jiangtao Yu
Received December 1, 2024  Accepted December 16, 2024  
View: 472   Download: 64
Original Article
Plasma lipidomics and fungal peptide-based community analysis identifies distinct signatures of early mortality in acute liver failure
Neha Sharma, Sushmita Pandey, Gaurav Tripathi, Manisha Yadav, Nupur Sharma, Babu Mathew, Abhishak Gupta, Vasundhra Bindal, Sadam H. Bhat, Yash magar, Rimsha Saif, Sanju Yadav, Amritpal Kaur, Rakhi Maiwall, Shvetank Sharma, Shiv Kumar Sarin, Jaswinder Singh Maras
Received July 12, 2024  Accepted December 10, 2024  
View: 710   Download: 71
Review Article
Gut microbiota-mediated gut-liver axis: a breakthrough point for understanding and treating liver cancer
Chenyang Li, Chujun Cai, Chendong Wang, Xiaoping Chen, Bixiang Zhang, Zhao Huang
Received September 30, 2024  Accepted December 6, 2024  
View: 833   Download: 112
Prediction and Management of Small-for-Size Syndrome in Living Donor Liver Transplantation
Jia-hao Law, Alfred Wei-Chieh Kow
Received October 3, 2024  Accepted December 9, 2024  
View: 407   Download: 49
Original Article
Integrated Molecular Characterization of Sarcomatoid Hepatocellular Carcinoma
Rong-Qi Sun, Yu-Hang Ye, Ye Xu, Bo Wang, Si-Yuan Pan, Ning Li, Long Chen, Jing-Yue Pan, Zhi-Qiang Hu, Jia Fan, Zheng-Jun Zhou, Jian Zhou, Cheng-Li Song, Shao-Lai Zhou
Received August 21, 2024  Accepted December 6, 2024  
View: 794   Download: 86
GOLM1 promotes cholesterol gallstone formation via ABCG5-mediated cholesterol efflux in MASH livers
Yi-Tong Li, Wei-Qing Shao, Zhen-Mei Chen, Xiao-Chen Ma, Chen-He Yi, Bao-Rui Tao, Bo Zhang, Yue Ma, Guo Zhang, Rui Zhang, Yan Geng, Jing Lin, Jin-Hong Chen
Received August 12, 2024  Accepted December 5, 2024  
View: 927   Download: 159  Crossref: 1
Editorial
Reconsidering Treatment Indications for Chronic Hepatitis B: Insights from the TORCH-B Roll-Over Study
Chih-Wen Wang, Ming-Lung Yu
Received November 28, 2024  Accepted November 30, 2024  
View: 342   Download: 12
Letter to the Editor
Treatment response to nucleos(t)ide analogs in chronic hepatitis B with mildly elevated alanine aminotransferase
Jian Wang, Fei Cao, Chuanwu Zhu, Chao Wu, Rui Huang
Received October 29, 2024  Accepted November 29, 2024  
View: 324   Download: 16
Original Article
Cost-effectiveness and return on investment of hepatitis C virus elimination in China: A modelling study
Meiyu Wu, Jing Ma, Xuehong Wang, Sini Li, Chongqing Tan, Ouyang Xie, Andong Li, Aaron G Lim, Xiaomin Wan
Received August 13, 2024  Accepted December 2, 2024  
View: 697   Download: 104
Correspondence
HCV Self-Testing: Bridging Screening Gaps and Ensuring Cost-Effectiveness for Both High-Risk and Universal Populations
Gyeongseon Shin, Beom Kyung Kim, SeungJin Bae, Hankil Lee, Sang Hoon Ahn
Received November 23, 2024  Accepted November 26, 2024  
View: 306   Download: 19
Original Article
Current Burden of Steatotic Liver Disease and Fibrosis among Adults in the United States, 2017-2023
Donghee Kim, Pojsakorn Danpanichkul, Karn Wijarnpreecha, George Cholankeril, Rohit Loomba, Aijaz Ahmed
Received November 3, 2024  Accepted November 26, 2024  
View: 1617   Download: 295  Crossref: 3
Review
Microbiome-Centered Therapies for the Management of Metabolic Dysfunction-Associated Steatotic Liver Disease
Huma Saeed, Luis Antonio Díaz, Antonio Gil-Gómez, Jeremy Burton, Jasmohan Bajaj, Manuel Romero-Gomez, Marco Arrese, Juan Pablo Arab, Mohammad Qasim Khan
Received September 13, 2024  Accepted November 20, 2024  
View: 2496   Download: 226  Crossref: 1
Liquid Biopsy in Hepatocellular Carcinoma: Challenges, Advances, and Clinical Implications
Jaeho Park, Yi-Te Lee, Vatche G. Agopian, Jessica S Liu, Ekaterina K. Koltsova, Sungyong You, Yazhen Zhu, Hsian-Rong Tseng, Ju Dong Yang
Received July 10, 2024  Accepted November 25, 2024  
View: 941   Download: 119
Review Article
Mechanisms of HCC and cirrhosis development in concurrent steatotic liver disease and chronic hepatitis B
Saisai Zhang, Lung-Yi Mak, Man-Fung Yuen, Wai-Kay Seto
Received September 25, 2024  Accepted November 16, 2024  
View: 885   Download: 94
Review
Prospect of emerging treatments for HBV functional cure
Rex Wan-Hin Hui, Lung-Yi Mak, James Fung, Wai-Kay Seto, Man-Fung Yuen
Received September 29, 2024  Accepted November 14, 2024  
View: 1201   Download: 243  Crossref: 1
Editorial
Universal self-testing as a cost-effective weapon to eliminate hepatitis C virus in the Republic of Korea
Eun Sun Jang
Received November 5, 2024  Accepted November 7, 2024  
View: 337   Download: 8
Correspondence
Correspondence to editorials on “Safety and efficacy of HK-660S in patients with primary sclerosing cholangitis: A randomized double-blind phase 2a trial”
Woo Hyun Paik, Do Hyun Park
Received November 4, 2024  Accepted November 7, 2024  
View: 318   Download: 18
Review
Hepatitis E as a trigger for Acute-on-Chronic Liver Failure
Maria Buti, Juan Carlos Ruiz-Cobo, Rafael Esteban, Mar Riveiro-Barciela
Received September 5, 2024  Accepted November 7, 2024  
View: 852   Download: 91
Stem cell exosomes: new hope and future potential for relieving liver fibrosis
Lihua Li, Yongjie Liu, Kunpeng Wang, Jinggang Mo, Zhiyong Weng, Hao Jiang, Chong Jin
Received September 29, 2024  Accepted November 5, 2024  
View: 1364   Download: 204
Editorial
Stabilizing Hepatic Fatty Acid Oxidation: USP29 Secures Acyl-CoA Synthesis through ACSL5
Myeung Gi Choi, Na Young Lee, Ja Hyun Koo
Received October 31, 2024  Accepted November 1, 2024  
View: 460   Download: 40
A novel clinical trial for primary sclerosing cholangitis from Asia: all regional endeavors should improve global management of PSC
Atsumasa Komori
Received October 25, 2024  Accepted November 1, 2024  
View: 369   Download: 26
Correspondence
Correspondence on Letter Regarding “Contemporary Awareness of Viral Hepatitis between 2012 and 2022 among Korean Adults”
Chang Hun Lee, In Hee Kim, Sook-Hyang Jeong
Received October 25, 2024  Accepted November 1, 2024  
View: 392   Download: 9
Editorial
Challenges and Innovations in PSC Clinical Trials: Evaluating HK-660S and the Path Forward
Nilanga Nishad
Received October 24, 2024  Accepted October 31, 2024  
View: 308   Download: 21
Review
ALCOHOL-ASSOCIATED LIVER DISEASE: NATURAL HISTORY, MANAGEMENT AND NOVEL TARGETED THERAPIES
Edilmar Alvarado-Tapias, Elisa Pose, Jordi Gratacós, Ana Clemente-Sánchez, Hugo Hugo López-Pelayo, Ramón Bataller
Received August 24, 2024  Accepted October 29, 2024  
View: 1148   Download: 177  Crossref: 2
Editorial
Momentum Towards Simplifying and Expanding Treatment for Chronic Hepatitis B: The Body of Evidence Continues to Grow
Robert J. Wong
Received October 22, 2024  Accepted October 28, 2024  
View: 287   Download: 14
Letter to the Editor
Prevalence of steatotic liver disease and associated fibrosis in the general population: an epidemiological survey
Lin Guan, Xinhe Zhang, Shanghao Liu, Xiaolong Qi, Yiling Li
Received October 17, 2024  Accepted October 28, 2024  
View: 515   Download: 46
Snapshot
MODULATION OF LYMPHATIC VESSELS IN MANAGEMENT OF LIVER DISEASE AND COMPLICATIONS
Aarti Sharma, Pinky Juneja, Shiv K Sarin, Savneet Kaur
Received September 12, 2024  Accepted October 16, 2024  
View: 414   Download: 42
Correspondence
Reply to: “From invasive to intuitive: the emerging role of non-invasive models in hepatic decompensation”
Chuan Liu, Ling Yang, Hong You, Gao-Jun Teng, Xiaolong Qi
Received August 27, 2024  Accepted August 29, 2024  
View: 530   Download: 27
Editorial
From Invasive to Intuitive: The Emerging Role of Non-Invasive Models in Hepatic Decompensation
Akhil Deshmukh, Rakhi Maiwall
Received August 13, 2024  Accepted August 13, 2024  
View: 386   Download: 18
Review Article
Epidemiology of Metabolic Dysfunction-Associated Steatotic Liver Disease
Zobair M. Younossi, Markos Kalligeros, Linda Henry
Received June 6, 2024  Accepted August 15, 2024  
View: 5505   Download: 1,274  Crossref: 18
Criteria and prognostic models for patients with hepatocellular carcinoma undergoing liver transplantation
Meng Sha, Jun Wang, Jie Cao, Zhi-Hui Zou, Xiao-ye Qu, Zhi-feng Xi, Chuan Shen, Ying Tong, Jian-jun Zhang, Seogsong Jeong, Qiang Xia
Received April 30, 2024  Accepted August 12, 2024  
View: 1086   Download: 137  Crossref: 1
Review
Precision medicine and nucleotide-based therapeutics to treat MASH
Andrea Caddeo, Stefano Romeo
Received June 8, 2024  Accepted August 4, 2024  
View: 1947   Download: 346  Crossref: 3
Role of noninvasive tests in the prognostication of metabolic dysfunction-associated steatotic liver disease
Yue Wang, Sherlot Juan Song, Yichong Jiang, Jimmy Che-To Lai, Grace Lai-Hung Wong, Vincent Wai-Sun Wong, Terry Cheuk-Fung Yip
Received April 10, 2024  Accepted June 26, 2024  
DOI: https://doi.org/10.3350/cmh.2024.0246    [Epub ahead of print]
View: 4786   Download: 164  Crossref: 1

Clinical and
Molecular
Hepatology

Print ISSN: 2287-2728
Online ISSN: 2287-285X

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