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Review

June 23, 2021


Entecavir versus tenofovir in patients with chronic hepatitis B: Enemies or partners in the prevention of hepatocellular carcinoma
Sung Won Lee, Jonggi Choi, Seung Up Kim, et al.
Clin Mol Hepatol. 2021;27(3):402-412.

Over the past several decades, entecavir (ETV) and tenofovir disoproxil fumarate (TDF) have remained the first-line antiviral agents in several international guidelines. These two antiviral agents have shown similar short...

Review

December 3, 2020


Anti-fibrotic treatments for chronic liver diseases: The present and the future
Naoshi Odagiri, Tsutomu Matsubara, Misako Sato-Matsubara, et al.
Clin Mol Hepatol. 2021;27(3):413-424.

Liver fibrosis reflects tissue scarring in the liver due to the accumulation of excessive extracellular matrix in response to chronically persistent liver injury. Hepatocyte cell death can trigger capillarization of...

Review

December 3, 2020


β-blockers in advanced cirrhosis: More friend than enemy
Ki Tae Yoon, Hongqun Liu, Samuel S. Lee
Clin Mol Hepatol. 2021;27(3):425-436.

Nonselective beta-adrenergic blocker (NSBB) therapy for the prevention of initial and recurrent gastrointestinal bleeding in cirrhotic patients with gastroesophageal varices has been used for the past four decades. NSBB therapy...

Review

January 28, 2021


Changes in the epidemiology and management of bacterial infections in cirrhosis
Salvatore Piano, Marta Tonon, Paolo Angeli
Clin Mol Hepatol. 2021;27(3):437-445.

Patients with cirrhosis are susceptible to develop infections because of immune dysfunction, changes in microbiome and increase in bacterial translocation from the gut to systemic circulation. Bacterial infections can worse...

Original Article

February 2, 2021


Outcomes after liver transplantation in Korea: Incidence and risk factors from Korean transplantation registry
Jong Man Kim, Deok Gie Kim, Jihyun Kim, et al.
Clin Mol Hepatol. 2021;27(3):451-462.

Background/Aims: To analyze the incidence and risk factors of outcomes after liver transplantation (LT) in the Korean population. Methods: This study analyzed data from the liver cohort of Korean Organ Transplantation...

Original Article

February 15, 2021


Serum milk fat globule-EGF factor 8 protein as a potential biomarker for metabolic syndrome
Han Ah Lee, Jihwan Lim, Hyung Joon Joo, et al.
Clin Mol Hepatol. 2021;27(3):463-473.

Background/Aims: Useful biomarkers for metabolic syndrome have been insufficient. We investigated the performance of serum milk fat globule-EGF factor-8 (MFG-E8), the key mediator of inflammatory pathway, in diagnosis of metabolic...

Original Article

February 19, 2021


The impact of unrestricted access to direct-acting antiviral among incarcerated hepatitis C virus-infected patients
Yu Jun Wong, Prem Harichander Thurairajah, Rahul Kumar, et al.
Clin Mol Hepatol. 2021;27(3):474-485.

Background/Aims: Despite the disproportionally high prevalence rates of hepatitis C virus (HCV) amongst the incarcerated population, eradication remains challenging due to logistic and financial barriers. Although treatment prioritization based on...

Original Article

February 23, 2021


Loss-of-function HSD17B13 variants, non-alcoholic steatohepatitis and adverse liver outcomes: Results from a multi-ethnic Asian cohort
Yi-Wen Ting, Amanda Shen-Yee Kong, Shamsul Mohd Zain, et al.
Clin Mol Hepatol. 2021;27(3):486-498.

Background/Aims: 17β-hydroxysteroid dehydrogenase 13 (HSD17B13) variants were recently reported to have significantly lower odds of non-alcoholic fatty liver disease (NAFLD). This is a two-part study that aimed to evaluate the...

Original Article

February 26, 2021


Serum fibrosis index-based risk score predicts hepatocellular carcinoma in untreated patients with chronic hepatitis B
Lilian Yan Liang, Hye Won Lee, Vincent Wai-Sun Wong, et al.
Clin Mol Hepatol. 2021;27(3):499-509.

Background/Aims: Serum fibrosis scores comprised of common laboratory tests have high utility to assess severity of liver fibrosis. We aimed to derive and validate a hepatocellular carcinoma (HCC) risk score...
Current Issue
Volume 27(3); Jul 2021

Articles in E-pub version are posted online ahead of regular printed publication.

Original Article
Cost-effectiveness and long-term outcomes of liver transplantation using anti-HBc-positive grafts with hepatitis B immunoglobulin prophylaxis in Korea
Kyeong Deok Kim, Ji Eun Lee, Jong Man Kim, Okjoo Lee, Na Young Hwang, Jinsoo Rhu, Gyu-Seong Choi, Kyunga Kim, Jae-Won Joh
Received May 16, 2021  Accepted September 7, 2021  
Impact of everolimus on survival after liver transplantation for hepatocellular carcinoma
Incheon Kang, Jae Geun Lee, Sung Hoon Choi, Hyun Jeong Kim, Dai Hoon Han, Gi Hong Choi, Myoung Soo Kim, Jin Sub Choi, Soon Il Kim, Dong Jin Joo
Received February 5, 2021  Accepted July 22, 2021  
Association between serum TNF-α and sarcopenia in liver cirrhosis
Ji Won Han, Da In Kim, Hee Chul Nam, U Im Chang, Jin Mo Yang, Do Seon Song
Received March 15, 2021  Accepted June 30, 2021  
Sofosbuvir/velpatasvir plus ribavirin for Child-Pugh B and Child-Pugh C hepatitis C virus-related cirrhosis
Chen-Hua Liu, Chi-Yi Chen, Wei-Wen Su, Chun-Jen Liu, Ching-Chu Lo, Ke-Jhang Huang, Jyh-Jou Chen, Kuo-Chih Tseng, Chi-Yang Chang, Cheng-Yuan Peng, Yu-Lueng Shih, Chia-Sheng Huang, Wei-Yu Kao, Sheng-Shun Yang, Ming-Chang Tsai, Jo-Hsuan Wu, Po-Yueh Chen, Pei-Yuan Su, Jow-Jyh Hwang, Yu-Jen Fang, Pei-Lun Lee, Chi-Wei Tseng, Fu-Jen Lee, Hsueh-Chou Lai, Tsai‐Yuan Hsieh, Chun-Chao Chang, Chung-Hsin Chang, Yi-Jie Huang, Jia-Horng Kao
Received June 27, 2021  Accepted July 6, 2021  
Letter to the Editor
Impact of BCAAs and Frailty on the Management of Lenvatinib-related Fatigue in Patients with Hepatocellular Carcinoma
Shigeo Shimose, Shunji Koya, Takumi Kawaguchi, Keisuke Hirota, Sachiyo Yoshio, Takashi Niizeki, Hiroo Matsuse, Takuji Torimura
Received August 14, 2021  Accepted September 8, 2021  
Editorial
Microwave thermosphere vs radiofrequency ablation for hepatocellular carcinoma: Are we approaching the time to end the debate?
Man-Deuk Kim
Received August 29, 2021  Accepted September 3, 2021  
Leaky Gut-Derived TNF-α Causes Sarcopenia in Patients with Liver Cirrhosis
Takumi Kawaguchi, Takuji Torimura
Received August 7, 2021  Accepted August 26, 2021  
Review Article
Current knowledge about biomarkers of acute kidney injury in liver cirrhosis
Han Ah Lee, Yeon Seok Seo
Received May 29, 2021  Accepted July 28, 2021  
Review
Toward a complete cure for chronic hepatitis B: Novel therapeutic targets for hepatitis B virus
Sun Woong Kim, Jun Sik Yoon, Minjong Lee, Yuri Cho
Received March 26, 2021  Accepted July 18, 2021  
Treatment of direct oral anticoagulants in patients with liver cirrhosis and portal vein thrombosis
Ho Soo Chun, A Reum Choe, Minjong Lee, Yuri Cho, Hwi Young Kim, Kwon Yoo, Tae Hun Kim
Received April 12, 2021  Accepted June 6, 2021  

Clinical and
Molecular
Hepatology

Print ISSN: 2287-2728
Online ISSN: 2287-285X

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