Clinical and Molecular Hepatology

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Korean J Hepatol. 2008;14(2):206-212. Published online June 20, 2008.
DOI: https://doi.org/10.3350/kjhep.2008.14.2.206
Four cases of toxic Liver injury associated with Dictamnus dasycarpus
Abstract
We report four cases of toxic hepatitis that occurred after taking a decoction made by boiling down the root of Dictamnus dasycarpus. The four patients had a median age of 60 years, common symptoms of jaundice and general weakness, and stated that they had not consumed alcohol for at least 5 years. The markers of hepatitis A, B, and C were all negative in the patients. Abdominal ultrasonography revealed common bile ducts with normal diameters. Two of the cases were a mother and daughter, and the other two were sporadic. All of them had consumed a decoction made by boiling down the root of Dictamnus dasycarpus five or six times daily until several days before admission. Dictamnus dasycarpus induced liver injury presenting with a benign course lasting less than 1 month after cessation of the causative agent. We suggest that this natural product can cause acute hepatitis in rural areas. (Korean J Hepatol 2008;14:206-212)

Keywords :Dictamnus dasycarpus; Herbal medicine; Toxic liver injury

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