A case of Liver metastasis of gastric hepatoid adenocarcinoma |
Eun Hyoung Jeong, M.D., Dong Hyun Kim, M.D., Sung Ho Ma, M.D.,
Eui Jong Chung, M.D., Sang Su Bae, M.D., A Young Park, M.D.1,
Hyung Jun Chu, M.D. |
Department of Internal Medicine, 1Pathology, Hong Ik General Hospital, Seoul, Korea |
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ABSTRACT |
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We report herein a case of hepatoid adenocarcinoma of the stomach with liver metastasis. Gastric carcinoma
generally presents as adenocarcinoma and rarely shows a hepatoid pattern, which can produce alphafetoprotein
(AFP). The stomach is one of the common sites at which hepatoid adenocarcinoma has been
detected. A 75-year-old female patient was admitted to the hospital with a symptom of epigastric discomfort.
Gastrofibroscopy revealed a large tumor occupying the greater curvature of the stomach body. The level of
serum AFP was markedly increased. Abdominal computed tomography revealed multiple liver masses. Biopsy
samples of the gastric lesion and liver masses finally confirmed her case as hepatoid adenocarcinoma in the
stomach with liver metastasis. The AFP-producing gastric carcinoma needs special attention because it often
presents with early liver metastasis and has a poor prognosis. (Korean J Hepatol 2009;15:201-208) |
KeyWords:
Hepatoid adenocarcinoma; Liver metastasis; Alpha-fetoprotein |
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