A Case of Fulminant Hepatic Failure Secondary to Hepatic Metastasis of Small Cell Lung Carcinoma

doi:2007.13.4.565

Korean J Hepatol > Volume 13(4); 2007 > Article

The Korean Journal of Hepatology 2007;13(4): 565-570.
doi: https://doi.org/10.3350/kjhep.2007.13.4.565

A Case of Fulminant Hepatic Failure Secondary to Hepatic Metastasis of Small Cell Lung Carcinoma

Young Tae Hwang, M.D.1, Jung Woo Shin, M.D.1, Jun Ho Lee, M.D.1, Dae Sung Hwang, M.D.1, Jun Bum Eum, M.D.1, Hye Jeong Choi, M.D.2, Neung Hwa Park, M.D.1

1Department of Internal Medicine, 2Department of Pathology, University of Ulsan College of Medicine, Ulsan University Hospital, Ulsan, Korea

ABSTRACT

Although liver metastasis is commonly found in cancer patients, fulminant hepatic failure secondary to diffuse cancer infiltration into the liver is rare. Liver metastasis-induced fulminant hepatic failure has been reported in patients with primary cancer of the gastrointestinal tract, breast and uroepithelium, and in patients with melanoma and hematologic malignancy. Small cell lung cancer is so highly invasive that hepatic metastasis is common, but rapid progression to fulminant hepatic failure is extremely rare. We report here on a case of a patient who died because of rapid progression to fulminant hepatic failure as a result of hepatic metastasis of small cell lung carcinoma. (Korean J Hepatol 2007;13:565-570)

KeyWords: Liver failure, acute; Small cell carcinoma; Liver metastasis