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CASE REPORTS  
CMH 2002 September;8:321-326.
Published online 1970 January 01.
Copyright © 2002 The Korean Association for the Study of the Liver
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A Case of Idiopathic Hypereosinophilic Syndrome with Hepatic Involvement in a 5 - Year - Old Boy
Young Mi Kim, M.D., Yoon Jin Lee, M.D., Jae Hong Park, M.D., Jun Woo Lee, M.D.1, and Chang Hun Lee, M.D.2
Department of Pediatrics, Radiology1 and Pathology2, College of Medicine, Pusan National University, Pusan, Korea
ABSTRACT
Idiopathic hypereosinophilic syndrome is defined as the presence of prolonged eosinophilia without an identifiable underlying cause and with evidence of end-organ dysfunction. The organs involved are the heart, bone marrow, nervous system, lungs, liver, skin, and gastrointestinal tract. Hepatic involvement is found in about 30% of patients of idiopathic hypereosinophilic syndrome. It occurs rarely in infants and children. In this report, we experienced one case of idiopathic hypereosinophilic syndrome with hepatic involvement in a 5-year-old boy who complained of intermittent fever and right upper quadrant abdominal pain. An abdominal ultrasound examination revealed an ill-defined low-echoic lesion in the liver. Pathologic findings of a biopsy specimen clearly showed the infiltration of eosinophils in the liver. Laboratory data disclosed absolute eosinophilia. There was no evidence of allergic disease or parasitic infestation. (Korean J Hepatol 2002;8:321-326)
Keywords: Idiopathic hypereosinophilic syndrome, Hepatic involvement
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