Clinical and Molecular Hepatology

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Korean J Hepatol. 2001;7(3):330-335. Published online January 1, 2000.
A Case of Spontaneous Necm4 of Hepatoellular Carcinoma after Development of Pneumonia
Abstract
Spontaneous regression of hepatocellular carcinoma is an extraordinarily rare phenomenon. Fewer than 20 occasions have been reported in the English medical literature. There have only been 5 case reports in Korea. Understanding of the mechanism of spontaneous regression of hepatocellular carcinoma will help us to establish new treatments for the disease. In this case report, we present a 53 year-old Asian male who showed spontaneous necrosis of hepatocellular carcinoma confirmed with pathology. He developed a febrile condition secondary to pneumonia for 2 weeks. After that hepatocellular carcinoma was observed to have been necrosed on an MRI scan and hepatic angiography. A right lobectomy of the liver was done because the possibility of residual microscopic cancer cells could not be ruled out. The pathologic finding confirmed the spontaneous near-total necrosis of hepatocellular carcinoma. The patient has recovered uneventfully and has been followed up for 7 months.(Korean J Hepatol 2001;7:330-335)

Keywords :Neoplasm/Liver/Hepatocellular Carcinoma, Spontaneous Necrosis, Pneumonia

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