Korean J Hepatol > Volume 11(4); 2005 > Article
The Korean Journal of Hepatology 2005;11(4): 339-349.
Comparison of Liver Abscess between Diabetic Patients and Non-Diabetic Patients
Chang Jae Lee, M.D., Dong Sik Jung, M.D., Suk Hee Jung, M.D., Jung Hoan Baik, M.D., Jung Hyun Lee, M.D., Young Rak Cho, M.D., Byoung Soung Go, M.D., Sung Wook Lee, M.D., Sang Young Han, M.D. and Dong Hyun Lee, M.D.1
Division of Gastroenterology, Department of Internal Medicine, College of Medicine, Dong-A University, Busan, Korea, Good Gang-An Hospital, Busan, Korea
ABSTRACT
Background/Aims
Klebsiella pneumoniae is emerging as the leading cause for liver abscess although the most common pathogen was Escherichia coli in the past. Patients with diabetes mellitus are more likely to have a pyogenic liver abscess with gas forming infection; a gas forming pyogenic liver abscess carries a higher morbidity and mortality than the non-gas forming group. This study was conducted to clarify the clinical presentation and prognostic factors for pyogenic liver abscess in diabetic patients compared with non-diabetic patients. Methods: Medical records of 140 cases of patients treated for pyogenic liver abscess from January 1995 through January 2004 were reviewed retrospectively in detail. Results: Among 140 cases of pyogenic liver abscess, underlying diabetes was present in 26.4% (37/140). The clinical presentation between the two groups was not significantly different. The most common organism for the pyogenic abscess was K. pneumoniae in both groups. A gas forming liver abscess was discovered in only the diabetic liver abscess group, 6 of 37 patients (16%). Conclusions: K. pneumoniae was the most common organism cultured in both diabetic and non-diabetic liver abscess. Gas forming liver abscess was more common in diabetic patients than non-diabetic patients. Diabetic patients had more complications than non-diabetic patients.(Korean J Hepatol 2005;11:339-349)
KeyWords: Liver abscess, Diabetics mellitus, Klebsiella pneumoniae, Gas forming liver abscess

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