Korean J Hepatol > Volume 11(3); 2005 > Article
The Korean Journal of Hepatology 2005;11(3): 289-292.
A Case of Primary Small Cell Carcinoma of the Liver
Seung Hoon Ryu, M.D., Sang Young Han, M.D., Sung Hwan Suh, M.D., Young Hun Koo, M.D., Jeong Hwan Cho, M.D., Seung Ho Han, M.D., Sung Wook Lee, M.D., Jin Han Cho, M.D.1, and Jin Sook Jeong, M.D.2
Department of Internal Medicine, Diagnostic Radiology1, and Pathology2, Dong-A University College of Medicine, Busan, Korea
ABSTRACT
Primary small cell carcinoma of the liver is an extremely rare tumor. Extrapulmonary small cell carcinoma shares many features of pulmonary small cell carcinoma, including the histological appearance, the aggressive clinical behavior and the frequent short-lasting response to either chemotherapy or radiotherapy. We experienced a 56-year-old man with small cell carcinoma that arose in the liver. Abdominal CT scan showed an 8 cm size, low density mass in the segment 4 of the liver and also multiple lymphadenopathies. Chest X-ray showed no abnormal finding, but the chest CT showed a right lower paratracheal lymphadenopathy. The pathological findings showed nests of small round cells with fine granular chromatin, inconspicuous nucleoli and scanty cytoplasm. Distinct and strong immunoreactions were seen for CD56 and c-kit, and sparse immunoreaction was seen for synaptophysin. Thyroid transcription factor-1 showed no immunoreaction. The tumor did not decrease in size despite chemotherapy. We report this case along with a review of the relevant literatures. (Korean J Hepatol 2005;11:289-292)
KeyWords: Small cell carcinoma, Liver

Editorial Office
The Korean Association for the Study of the Liver
Room A1210, 53 Mapo-daero(MapoTrapalace, Dowha-dong), Mapo-gu, Seoul, 04158, Korea
TEL: +82-2-703-0051   FAX: +82-2-703-0071    E-mail: kasl@kams.or.kr
Copyright © The Korean Association for the Study of the Liver.         
COUNTER
TODAY : 1627
TOTAL : 1735522
Close layer