Korean J Hepatol > Volume 10(3); 2004 > Article
The Korean Journal of Hepatology 2004;10(3): 228-232.
Extrahepatic Metastasis of Hepatocellular Carcinoma to the Nasal Cavity Manifested as Massive Epistaxis: A Case Report
Sung Jae Yoo, M.D., Jae Hee Cheon, M.D., Sang Won Lee, M.D., Yoo Seok Jung, M.D. , Sang Hyun Lee, M.D., Joong-Won Park, M.D.*, Eun Kyoung Hong, M.D.* and Chang-Min Kim, M.D.*
Center for Liver Cancer, Hepatobilliary-pancreatic Cancer Branch*, Center for Specific Organs Cancer , National Cancer Center, Goyang, Korea
Extrahepatic metastasis of hepatocellular carcinoma (HCC) is not infrequently found during the later stage, regarding that the autopsy report described its prevalence to be up to 50%. The most frequent sites are known to be the abdominal lymph nodes, lung and bone. However, metastasis to the nasal cavity and paranasal sinuses has been seldom reported, and to out know ledge, there is no Korean report describing extrahepatic metastasis of HCC to these sites. Recently we experienced a case of extrahepatic metastasis of HCC to the nasal cavity in a 50 year-old man with massive epistaxis refractory to conservative treatment. He was found to have a mass of soft tissue attenuation occupying the right nasal cavity at CT, which w as biopsy-proven as metastatic HCC. Epistaxis was successfully treated by transcatheter arterial embolization. (Korean J Hepatol 2004;10:228-232)
KeyWords: Hepatocellular carcinoma, Metastasis, Nasal cavity, Epistaxis

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