Clin Mol Hepatol > Volume 29(1); 2023 > Article
Mungmunpuntipantip and Wiwanitkit: Letter regarding “COVID-19 vaccine immunogenicity among chronic liver disease patients and liver transplant recipients: A meta-analysis”
Dear Editor,
We would like to share ideas on “COVID-19 vaccine immunogenicity among chronic liver disease patients and liver transplant recipients: A meta-analysis.” [1] In contrast to liver transplant recipients, patients with chronic liver disease exhibited a good humoral response to the coronavirus disease 2019 (COVID-19) vaccination, according to Cheung et al. [1]. We also agree that COVID-19 is helpful in immunogenicity. The immunological response of a vaccine recipient with an underlying medical condition may be different from that of a healthy individual. Potential confounding factors must be taken into consideration while interpreting the current report. Prior asymptomatic COVID-19 infection is a possibility, and is not unusual [2]. If there is no method to rule out prior cases of asymptomatic COVID-19, it would be challenging to evaluate the effectiveness of the vaccine.

FOOTNOTES

Authors’ contributions
RM: 50% ideas, writing, approval for submission; VW: 50% ideas, supervision, approval for submission
Conflicts of Interest
The authors declare no conflicts of interest.

Abbreviations

COVID-19
coronavirus disease 2019

REFERENCES

1. Cheung KS, Mok CH, Mao X, Zhang R, Hung IF, Seto WK, et al. COVID-19 vaccine immunogenicity among chronic liver disease patients and liver transplant recipients: a meta-analysis. Clin Mol Hepatol 2022. 28:890-911.
crossref pmid pmc pdf
2. Joob B, Wiwanitkit V. Letter to the editor: coronavirus disease 2019 (COVID-19), infectivity, and the incubation period. J Prev Med Public Health 2020. 53:70.
crossref pmid pmc pdf

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