| 증례 : 비가족성 양성 재발성 간내 담즙울체증 1 예 ( Case Reports : A Case of Nonfamilial Benign Recurrent Intrahepatic Cholestasis ) |
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| A Case of Nonfamilial Benign Recurrent Intrahepatic Cholestasis |
| Oh Young Kim , Bum Yong Sung , Gyo Don Kowg , Hae Seoung Yoon , Yong Min Shin , Hyun Taek Oh , Mi Kyoung Kim , Hyeong Kweon Kim , Ju Ho Kim , Kwang Ung Ri , Hyun I Shon |
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| ABSTRACT |
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Benign recurrent intrahepatic cholestasis (BRIC) is a rare desease, which usually manifests between the age of 10 and 20. Its main clinical feature is multiple recurrent episodes of cholestasis without extrahepatic bile duct obstruction. We report here a case of nonfamilial benign recurrent intrahepatic cholestasis. The patient has experienced recurrent jaundice with pruritus since childhood. Main bile duct obstrution was excluded by abdominal CT and endoscopic retrograde cholangiopancreatography. Other causes of cholestasis were not found. Hepatic histology revealed bile plug which were mainly concentrated in the centrilobular region, and increased number of mononuclear cells in the portal triad, but hepatic parenchyma showed no inflammation and necrosis. In the last anicteric period, she was healthy and the liver function test and biopsy specimen were normal. (Korean J Hepatol 1998;4:188 - 193) |
| KeyWords:
Benign recurrent intrahepatic cholestasis , Nonfamilial form |
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