CMH :: Clinical and Molecular Hepatology

Non-linear associations of circulating total bilirubin concentration with the risk of nonalcoholic fatty liver disease and all-cause mortality

Hui Han, Qingtao Yu, Nina Qin, Bin Song, Yan Meng, Zuojing Feng, Zhaoping Li, Liyong Chen

Annals of Hepatology.2024; 29(2): 101177. CrossRef

Inverse association between total bilirubin and type 2 diabetes in U.S. South Asian males but not females

Aayush Visaria, Alka Kanaya, Soko Setoguchi, Meghana Gadgil, Jaya Satagopan, Fredirick Lazaro mashili

Hepatotoxicity induced in rats by chronic exposure to F–53B, an emerging replacement of perfluorooctane sulfonate (PFOS)

Xiaohan Li, Qian Zhang, Aiqing Wang, Shan Shan, Xueying Wang, Yarong Wang, Jianmei Wan, Ping Ning, Chengjiao Hong, Hailin Tian, Yun Zhao

Environmental Pollution.2024; 346: 123544. CrossRef

5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside Attenuates High Fat, High Fructose Diet-induced Fatty Liver and Fibrosis in Mice.

Biomedical and Pharmacology Journal.2024; 17(1): 383. CrossRef

Bilirubin Levels Are Negatively Correlated with Adiposity in Obese Men and Women, and Its Catabolized Product, Urobilin, Is Positively Associated with Insulin Resistance

Zachary A. Kipp, Mei Xu, Evelyn A. Bates, Wang-Hsin Lee, Philip A. Kern, Terry D. Hinds

Dietary fiber intake and non-alcoholic fatty liver disease: The mediating role of obesity

Yu Zhu, Hu Yang, Yaozong Zhang, Songxian Rao, Yufeng Mo, Honghua Zhang, Shaoxian Liang, Zhuang Zhang, Wanshui Yang

Suppressing Hepatic UGT1A1 Increases Plasma Bilirubin, Lowers Plasma Urobilin, Reorganizes Kinase Signaling Pathways and Lipid Species and Improves Fatty Liver Disease

Evelyn A. Bates, Zachary A. Kipp, Genesee J. Martinez, Olufunto O. Badmus, Mangala M. Soundarapandian, Donald Foster, Mei Xu, Justin F. Creeden, Jennifer R. Greer, Andrew J. Morris, David E. Stec, Terry D. Hinds

Association of per- and polyfluoroalkyl substance exposure with fatty liver disease risk in US adults

Xinyuan Zhang, Longgang Zhao, Alan Ducatman, Chuanjie Deng, Katherine Ellen von Stackelberg, Christopher J. Danford, Xuehong Zhang

Nanodrug delivery systems for metabolic chronic liver diseases: advances and perspectives

Foteini Athanasopoulou, Michail Manolakakis, Santiago Vernia, Nazila Kamaly

Assessing the causal relationships between human blood metabolites and the risk of NAFLD: A comprehensive mendelian randomization study

Ziwei Guo, Tingyu Zhang, Zhangjun Yun, Qian Jin, Xu Cao, Deming Kong, Yuhao Yao, Xiaoke Li, Jiaxin Zhang, Yong’An Ye

Association between remnant lipoprotein cholesterol levels and risk of non-alcoholic fatty liver disease in non-obese populations: a Chinese longitudinal prospective cohort study

A low‐energy total diet replacement program demonstrates a favorable safety profile and improves liver disease severity in nonalcoholic steatohepatitis

Dimitrios A. Koutoukidis, Ferenc E. Mozes, Susan A. Jebb, Jeremy W. Tomlinson, Michael Pavlides, Francesca Saffioti, Rosemary Huntriss, Paul Aveyard, Jeremy F. Cobbold

Hyperbilirubinemia in hospitalized patients: Etiology and outcomes

Journal of Investigative Medicine.2023; 71(7): 773. CrossRef

The relationship of serum bilirubin level with histopathological parameters in patients with nonalcoholic fatty liver disease

Ali KIRIK, Cemal Nuri ERCİN, Hasan GÜREL, Ali Fuat ÇİÇEK, Ali Cem YEKDEŞ, Sultan TÜREL, Serkan TAPAN, Teoman DOĞRU

Impact of obesity on liver function tests: is nonalcoholic fatty liver disease the only player? A review article

Bilirubin represents a negative regulator of ILC2 in allergic airway inflammation

Juan He, Guanmin Jiang, Xing Li, Qiang Xiao, Yingying Chen, Haixu Xu, Gaoyu Liu, Aihua Lei, Pan Zhou, Kun Shi, Quan Yang, Meng Zhao, Zhi Yao, Jie Zhou

Heme-oxygenase and lipid mediators in obesity and associated cardiometabolic diseases: Therapeutic implications

John A. McClung, Lior Levy, Victor Garcia, David E. Stec, Stephen J. Peterson, Nader G. Abraham

Pharmacology & Therapeutics.2022; 231: 107975. CrossRef

Multiomics Analysis Reveals the Impact of Microbiota on Host Metabolism in Hepatic Steatosis

Mujdat Zeybel, Muhammad Arif, Xiangyu Li, Ozlem Altay, Hong Yang, Mengnan Shi, Murat Akyildiz, Burcin Saglam, Mehmet Gokhan Gonenli, Buket Yigit, Burge Ulukan, Dilek Ural, Saeed Shoaie, Hasan Turkez, Jens Nielsen, Cheng Zhang, Mathias Uhlén, Jan Borén, Ad

Serum Bilirubin Level Is Increased in Metabolically Healthy Obesity

Hepatoprotection of Probiotics Against Non-Alcoholic Fatty Liver Disease in vivo: A Systematic Review

Faezah Sabirin, Siong Meng Lim, Chin Fen Neoh, Kalavathy Ramasamy

Assessment of efficacy and safety of two Egyptian protocols for treatment-experienced HCV patients: an observational study

Radwa Samir Hagag, Morkoss Medhat Fakhry, Ossama Ashraf Ahmed, Shaimaa Abdalaleem Abdalgeleel, Mahasen Aly Radwan, Gina Gamal Naguib

The Egyptian Journal of Internal Medicine.2022;[Epub] CrossRef

Association of Serum Bilirubin With Metabolic Syndrome and Non-Alcoholic Fatty Liver Disease: A Systematic Review and Meta-Analysis

Chen Liang, Zhiyuan Yu, Li Bai, Wei Hou, Shan Tang, Wei Zhang, Xinyue Chen, Zhongjie Hu, Zhongping Duan, Sujun Zheng

Elevated alpha-fetoprotein in asymptomatic adults: Clinical features, outcome, and association with body composition

Sangmi Jang, Gwang Hyeon Choi, Won Chang, Eun Sun Jang, Jin-Wook Kim, Sook-Hyang Jeong, Nobuyuki Takahashi

Effects of vitamin E on neonatal hyperbilirubinemia in preterm newborns

Behzad Barekatain, Alireza Sadeghnia, Nahid Moradi, Maryam Yazdi

Advanced Biomedical Research.2022; 11(1): 86. CrossRef

Molecular mechanisms of metabolic associated fatty liver disease (MAFLD): functional analysis of lipid metabolism pathways

Olufunto O. Badmus, Sarah A. Hillhouse, Christopher D. Anderson, Terry D. Hinds, David E. Stec

Higher Adherence to Healthy Lifestyle Score Is Associated with Lower Odds of Non-Alcoholic Fatty Liver Disease

Yu Zhu, Hu Yang, Shaoxian Liang, Honghua Zhang, Yufeng Mo, Songxian Rao, Yaozong Zhang, Zhuang Zhang, Weiqiang Wang, Wanshui Yang

Role of Seaweeds in Drug Induced Nephrotoxicity

Marine Science and Technology Bulletin.2022; 11(4): 515. CrossRef

Novel Function for Bilirubin as a Metabolic Signaling Molecule: Implications for Kidney Diseases

David E. Stec, Claudio Tiribelli, Olufunto O. Badmus, Terry D. Hinds

Effect of 2 years of calorie restriction on liver biomarkers: results from the CALERIE phase 2 randomized controlled trial

James L. Dorling, Eric Ravussin, Leanne M. Redman, Manju Bhapkar, Kim M. Huffman, Susan B. Racette, Sai K. Das, John W. Apolzan, William E. Kraus, Christoph Höchsmann, Corby K. Martin

European Journal of Nutrition.2021; 60(3): 1633. CrossRef

Bilirubin as a metabolic hormone: the physiological relevance of low levels

Justin F. Creeden, Darren M. Gordon, David E. Stec, Terry D. Hinds

American Journal of Physiology-Endocrinology and Metabolism.2021; 320(2): E191. CrossRef

Association of Serum Bilirubin Level with Metabolic Syndrome and Non-Alcoholic Fatty Liver Disease: A Cross-Sectional Study of 1672 Obese Children

Cristina Bellarosa, Giorgio Bedogni, Annalisa Bianco, Sabrina Cicolini, Diana Caroli, Claudio Tiribelli, Alessandro Sartorio

Journal of Clinical Medicine.2021; 10(13): 2812. CrossRef

Crosstalk Between Plasma Cytokines, Inflammation, and Liver Damage as a New Strategy to Monitoring NAFLD Progression

Tereza C. M. Fontes-Cal, Rafael T. Mattos, Nayara I. Medeiros, Bruna F. Pinto, Mayara Belchior-Bezerra, Bruna Roque-Souza, Walderez O. Dutra, Teresa C. A. Ferrari, Paula V. T. Vidigal, Luciana C. Faria, Cláudia A. Couto, Juliana A. S. Gomes

Is a Four-Week Ketogenic Diet an Effective Nutritional Strategy in CrossFit-Trained Female and Male Athletes?

Krzysztof Durkalec-Michalski, Paulina M. Nowaczyk, Natalia Główka, Anna Ziobrowska, Tomasz Podgórski

Oxidative Stress and Related Biomarkers in Gilbert’s Syndrome: A Secondary Analysis of Two Case-Control Studies

Karl-Heinz Wagner, Nazlisadat Seyed Khoei, Claudia Hana, Daniel Doberer, Rodrig Marculescu, Andrew Bulmer, Marlies Hörmann-Wallner, Christine Mölzer

Bilirubin deficiency renders mice susceptible to hepatic steatosis in the absence of insulin resistance

Weiyu Chen, Sergey Tumanov, Daniel J. Fazakerley, James Cantley, David E. James, Louise L. Dunn, Taqi Shaik, Cacang Suarna, Roland Stocker

Biliverdin reductase as a target in drug research and development: Facts and hypotheses

Free Radical Biology and Medicine.2021; 172: 521. CrossRef

Association of Serum Bilirubin and Functional Variants of Heme Oxygenase 1 and Bilirubin UDP-Glucuronosyl Transferase Genes in Czech Adult Patients with Non-Alcoholic Fatty Liver Disease

Jaromír Petrtýl, Karel Dvořák, Jan Stříteský, Martin Leníček, Alena Jirásková, Václav Šmíd, Martin Haluzík, Radan Brůha, Libor Vítek

Circulating chemerin level is associated with metabolic, biochemical and haematological parameters—A population‐based study

Hsin‐Hua Chou, Ming‐Sheng Teng, Lung‐An Hsu, Leay‐Kiaw Er, Semon Wu, Yu‐Lin Ko

Clinical Endocrinology.2021; 94(6): 927. CrossRef

The effects of Ramadan intermittent fasting on liver function in healthy adults: A systematic review, meta-analysis, and meta-regression

MoezAlIslam Faris, Haitham Jahrami, Dana Abdelrahim, Nicola Bragazzi, Ahmed BaHammam

Diabetes Research and Clinical Practice.2021; 178: 108951. CrossRef

The Protective Role of the Heme Catabolic Pathway in Hepatic Disorders

Antioxidants & Redox Signaling.2021; 35(9): 734. CrossRef

Circulating total bilirubin and risk of non-alcoholic fatty liver disease in the PREVEND study: observational findings and a Mendelian randomization study

Setor K. Kunutsor, Monika Frysz, Niek Verweij, Lyanne M. Kieneker, Stephan J. L. Bakker, Robin P. F. Dullaart

European Journal of Epidemiology.2020; 35(2): 123. CrossRef

Heme-Derived Metabolic Signals Dictate Immune Responses

Giacomo Canesin, Seyed M. Hejazi, Kenneth D. Swanson, Barbara Wegiel

Renal resistive index in non-alcoholic fatty liver disease as an indicator of early renal affection

Hossam El-Din A. Mahmoud, Wael A. Yousry, Shereen A. Saleh, Mohamed El Badry, Ahmed Hussein, Mostafa Hassan Ali, Hazem M. El-Hariri

Plasma Krebs Cycle Intermediates in Nonalcoholic Fatty Liver Disease

Yana Sandlers, Rohan R. Shah, Ryan W. Pearce, Jaividhya Dasarathy, Arthur J. McCullough, Srinivasan Dasarathy

Journal of Clinical Medicine.2020; 9(2): 314. CrossRef

Physiological changes in the albumin-bound non-esterified free fatty acids critically influence heme/bilirubin binding properties of the protein: A comparative, in vitro, spectroscopic study using the endogenous biomolecules

Mahtab Amoorahim, Mohammad Reza Ashrafi-Kooshk, Sajjad Esmaeili, Mohsen Shahlaei, Sajad Moradi, Reza Khodarahmi

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy.2020; 235: 118298. CrossRef

Long-term profile of serological biomarkers, hepatic inflammation, and fibrosis in a mouse model of non-alcoholic fatty liver disease

Bilirubin remodels murine white adipose tissue by reshaping mitochondrial activity and the coregulator profile of peroxisome proliferator–activated receptor α

Darren M. Gordon, Kari L. Neifer, Abdul-Rizaq Ali Hamoud, Charles F. Hawk, Andrea L. Nestor-Kalinoski, Scott A. Miruzzi, Michael P. Morran, Samuel O. Adeosun, Jeffrey G. Sarver, Paul W. Erhardt, Robert E. McCullumsmith, David E. Stec, Terry D. Hinds

Journal of Biological Chemistry.2020; 295(29): 9804. CrossRef

Therapeutic application and construction of bilirubin incorporated nanoparticles

Qing Yao, Ruijie Chen, Vadivel Ganapathy, Longfa Kou

Journal of Controlled Release.2020; 328: 407. CrossRef

Rats Genetically Selected for High Aerobic Exercise Capacity Have Elevated Plasma Bilirubin by Upregulation of Hepatic Biliverdin Reductase-A (BVRA) and Suppression of UGT1A1

Terry D. Hinds, Justin F. Creeden, Darren M. Gordon, Adam C. Spegele, Steven L. Britton, Lauren G. Koch, David E. Stec

A Nomogram Model Based on Noninvasive Bioindicators to Predict 3-Year Risk of Nonalcoholic Fatty Liver in Nonobese Mainland Chinese: A Prospective Cohort Study

Xintian Cai, Xiayire Aierken, Ayguzal Ahmat, Yuanyuan Cao, Qing Zhu, Ting Wu, Nanfang Li, Marcello Maida

BioMed Research International.2020; 2020: 1. CrossRef

Reduced Biliverdin Reductase-A Expression in Visceral Adipose Tissue is Associated with Adipocyte Dysfunction and NAFLD in Human Obesity

Valentina Ceccarelli, Ilaria Barchetta, Flavia Agata Cimini, Laura Bertoccini, Caterina Chiappetta, Danila Capoccia, Raffaella Carletti, Claudio Di Cristofano, Gianfranco Silecchia, Mario Fontana, Frida Leonetti, Andrea Lenzi, Marco Giorgio Baroni, Eugeni

International Journal of Molecular Sciences.2020; 21(23): 9091. CrossRef

Natural Product Heme Oxygenase Inducers as Treatment for Nonalcoholic Fatty Liver Disease

International Journal of Molecular Sciences.2020; 21(24): 9493. CrossRef

Bilirubin Nanoparticles Reduce Diet-Induced Hepatic Steatosis, Improve Fat Utilization, and Increase Plasma β-Hydroxybutyrate

Terry D. Hinds, Justin F. Creeden, Darren M. Gordon, Donald F. Stec, Matthew C. Donald, David E. Stec

Serum lactate levels are associated with serum alanine aminotransferase and total bilirubin levels in patients with type 2 diabetes mellitus: A cross-sectional study

Minori Ishitobi, Toshio Hosaka, Naru Morita, Ken Kondo, Toshitaka Murashima, Atsuko Kitahara, Kazuto Takahashi, Yoshikazu Sumitani, Toshiaki Tanaka, Toshihiko Yokoyama, Takuma Kondo, Hitoshi Ishida

Diabetes Research and Clinical Practice.2019; 149: 1. CrossRef

Reduced biliverdin reductase-A levels are associated with early alterations of insulin signaling in obesity

Flavia Agata Cimini, Andrea Arena, Ilaria Barchetta, Antonella Tramutola, Valentina Ceccarelli, Chiara Lanzillotta, Mario Fontana, Laura Bertoccini, Frida Leonetti, Danila Capoccia, Gianfranco Silecchia, Claudio Di Cristofano, Caterina Chiappetta, Fabio D

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease.2019; 1865(6): 1490. CrossRef

Western Diet-Induced Metabolic Alterations Affect Circulating Markers of Liver Function before the Development of Steatosis

Daniela Gabbia, Marco Roverso, Maria Guido, Diana Sacchi, Michela Scaffidi, Maria Carrara, Genny Orso, Francesco Paolo Russo, Annarosa Floreani, Sara Bogialli, Sara De Martin

CRISPR Cas9-mediated deletion of biliverdin reductase A (BVRA) in mouse liver cells induces oxidative stress and lipid accumulation

Darren M. Gordon, Samuel O. Adeosun, Somtochukwu I. Ngwudike, Christopher D. Anderson, John E. Hall, Terry D. Hinds, David E. Stec

Archives of Biochemistry and Biophysics.2019; 672: 108072. CrossRef

Applying Non-Invasive Fibrosis Measurements in NAFLD/NASH: Progress to Date

Pharmaceutical Medicine.2019; 33(6): 451. CrossRef

Hepatoprotective Effects of a Ruthenium(II) Schiff Base Complex in Rats with Diet-Induced Prediabetes

Lindokuhle Patience Mabuza, Mlindeli Wilkinson Gamede, Sanam Maikoo, Irvin Noel Booysen, Phikelelani Siphosethu Nguban, Andile Khathi

Current Therapeutic Research.2019; 91: 66. CrossRef

Systemic regulation of bilirubin homeostasis: Potential benefits of hyperbilirubinemia

Ryoichi Fujiwara, Mathias Haag, Elke Schaeffeler, Anne T. Nies, Ulrich M. Zanger, Matthias Schwab

Abdul-Rizaq Hamoud, Lauren Weaver, David E. Stec, Terry D. Hinds

Trends in Endocrinology & Metabolism.2018; 29(3): 140. CrossRef

Biliverdin reductase and bilirubin in hepatic disease

Lauren Weaver, Abdul-rizaq Hamoud, David E. Stec, Terry D. Hinds

American Journal of Physiology-Gastrointestinal and Liver Physiology.2018; 314(6): G668. CrossRef

Bilirubin, a new therapeutic for kidney transplant?

Vikram L. Sundararaghavan, Sivjot Binepal, David E. Stec, Puneet Sindhwani, Terry D. Hinds

Transplantation Reviews.2018; 32(4): 234. CrossRef

Loss of biliverdin reductase-A promotes lipid accumulation and lipotoxicity in mouse proximal tubule cells

Samuel O. Adeosun, Darren M. Gordon, Mary Frances Weeks, Kyle H. Moore, John E. Hall, Terry D. Hinds, David E. Stec

American Journal of Physiology-Renal Physiology.2018; 315(2): F323. CrossRef

Genetically Regulated Bilirubin and Risk of Non-alcoholic Fatty Liver Disease: A Mendelian Randomization Study

Lei Luo, Ping An, Xinyong Jia, Xiaobian Yue, Sujun Zheng, Shuang Liu, Yu Chen, Wei An, Cheryl A. Winkler, Zhongping Duan

Relationship between serum bilirubin concentrations and diabetic nephropathy in Shanghai Han’s patients with type 1 diabetes mellitus

Xu Li, Lei Zhang, Haibing Chen, Kaifeng Guo, Haoyong Yu, Jian Zhou, Ming Li, Qing Li, Lianxi Li, Jun Yin, Fang Liu, Yuqian Bao, Junfeng Han, Weiping Jia

Mice with hyperbilirubinemia due to Gilbert’s syndrome polymorphism are resistant to hepatic steatosis by decreased serine 73 phosphorylation of PPARα

Terry D. Hinds, Peter A. Hosick, Shujuan Chen, Robert H. Tukey, Michael W. Hankins, Andrea Nestor-Kalinoski, David E. Stec

American Journal of Physiology-Endocrinology and Metabolism.2017; 312(4): E244. CrossRef

Does bilirubin protect against developing diabetes mellitus?

Journal of Diabetes and its Complications.2016; 30(4): 728. CrossRef

Association between bilirubin and risk of Non-Alcoholic Fatty Liver Disease based on a prospective cohort study

Jianbo Tian, Rong Zhong, Cheng Liu, Yuhan Tang, Jing Gong, Jiang Chang, Jiao Lou, Juntao Ke, Jiaoyuan Li, Yi Zhang, Yang Yang, Ying Zhu, Yajie Gong, Yanyan Xu, Peiyi Liu, Xiao Yu, Lin Xiao, Min Du, Ling Yang, Jing Yuan, Youjie Wang, Weihong Chen, Sheng We

Does bilirubin prevent hepatic steatosis through activation of the PPARα nuclear receptor?

Terry D. Hinds, Samuel O. Adeosun, Abdulhadi A. Alamodi, David E. Stec

Bilirubin Binding to PPARα Inhibits Lipid Accumulation

David E. Stec, Kezia John, Christopher J. Trabbic, Amarjit Luniwal, Michael W. Hankins, Justin Baum, Terry D. Hinds, Hervé Guillou

Total Bilirubin Levels Predict Subclinical Atherosclerosis in Patients With Prediabetes

Hikmet Hamur, Hakan Duman, Levent Demirtas, Eftal Murat Bakirci, Murtaza Emre Durakoglugil, Husnu Degirmenci, Kamuran Kalkan, Erkan Yildirim, Ertan Vuruskan

Biliverdin Reductase A Attenuates Hepatic Steatosis by Inhibition of Glycogen Synthase Kinase (GSK) 3β Phosphorylation of Serine 73 of Peroxisome Proliferator-activated Receptor (PPAR) α

Terry D. Hinds, Katherine A. Burns, Peter A. Hosick, Lucien McBeth, Andrea Nestor-Kalinoski, Heather A. Drummond, Abdulhadi A. AlAmodi, Michael W. Hankins, John P. Vanden Heuvel, David E. Stec

Journal of Biological Chemistry.2016; 291(48): 25179. CrossRef

Role of physical activity in nonalcoholic fatty liver disease in terms of visceral obesity and insulin resistance

Min‐Sun Kwak, Donghee Kim, Goh Eun Chung, Won Kim, Yoon Jun Kim, Jung‐Hwan Yoon

Looking to the horizon: the role of bilirubin in the development and prevention of age-related chronic diseases

Karl-Heinz Wagner, Marlies Wallner, Christine Mölzer, Silvia Gazzin, Andrew Cameron Bulmer, Claudio Tiribelli, Libor Vitek

Nonalcoholic Steatohepatitis Associated With Metabolic Syndrome

Kyong Yeun Jung, Sun Young Cho, Hyung Joon Kim, Suk Bae Kim, Il Han Song

Journal of Clinical Gastroenterology.2014; 48(10): 883. CrossRef

Low serum bilirubin concentration is a novel risk factor for the development of albuminuria in patients with type 2 diabetes

Hiroshi Okada, Michiaki Fukui, Muhei Tanaka, Shinobu Matsumoto, Kanae Kobayashi, Hiroya Iwase, Kiichiro Tomiyasu, Koji Nakano, Goji Hasegawa, Naoto Nakamura

The association between indirect bilirubin levels and liver fibrosis due to chronic hepatitis C virus infection

Pathology - Research and Practice.2014; 210(8): 488. CrossRef

Effect of Low Serum Total Bilirubin Levels (≤0.32 mg/dl) on Risk of Coronary Artery Disease in Patients With Metabolic Syndrome

Young Shin Song, Bo Kyung Koo, Nam H. Cho, Min Kyong Moon

The American Journal of Cardiology.2014; 114(11): 1695. CrossRef

Systematic review: Association of serum bilirubin and non-alcoholic fatty liver disease: A feasible therapeutic avenue?

World Journal of Pharmacology.2014; 3(4): 209. CrossRef

Non‐alcoholic fatty liver disease: Factors associated with its presence and onset

Teruki Miyake, Teru Kumagi, Shinya Furukawa, Yoshio Tokumoto, Masashi Hirooka, Masanori Abe, Yoichi Hiasa, Bunzo Matsuura, Morikazu Onji

Journal of Gastroenterology and Hepatology.2013; 28(S4): 71. CrossRef