![]() |
Gut-derived lipopolysaccharide promotes alcoholic hepatosteatosis and subsequent hepatocellular carcinoma by stimulating neutrophil extracellular traps through toll-like receptor 4
Yang Liu, Xin Zhang, Shuo Chen, Jiazhong Wang, Shuo Yu, Yiming Li, Meng Xu, Harouna Aboubacar, Junhui Li, Tao Shan, Jixin Wang, Gang Cao
Clin Mol Hepatol. 2022;28(3):522-539. Published online 2022 May 4 DOI: https://doi.org/10.3350/cmh.2022.0039
|
Citations to this article as recorded by
Lipopolysaccharide, arbiter of the gut–liver axis, modulates hepatic cell pathophysiology in alcoholism
Ki M. Mak, Aditya C. Shekhar
The Anatomical Record.2025; 308(3): 975. CrossRef Could intratumoural microbiota be key to unlocking treatment responses in hepatocellular carcinoma?
Kin Lam Yu, Sj Shen
European Journal of Cancer.2025; 216: 115195. CrossRef The dual role of neutrophils in sepsis-associated liver injury
Lexin Fang, Yu Song, Jiangtao Chen, Yueping Ding
Frontiers in Immunology.2025;[Epub] CrossRef Neutrophil extracellular traps mediate pathophysiology of hepatic cells during liver injury
Ki M. Mak, Aditya C. Shekhar, Selena Y. Ding
The Anatomical Record.2025;[Epub] CrossRef Roles of the gut microbiota in hepatocellular carcinoma: from the gut dysbiosis to the intratumoral microbiota
Yiqin Wang, Yongqiang Li, Yong Lin, Chuangyu Cao, Dongcheng Chen, Xianguang Huang, Canhua Li, Haoming Xu, Huasheng Lai, Huiting Chen, Yongjian Zhou
Cell Death Discovery.2025;[Epub] CrossRef Neutrophil elastase binds at the central domain of extracellular Toll-like receptor 4: AI prediction, docking, and validation in disease model
Azeem Ali, Leena Gaba, Sujata Jetley, Imran A. Khan, Prem Prakash
Scientific Reports.2025;[Epub] CrossRef Neutrophil extracellular traps (NETs) and NETosis in alcohol‐associated diseases: A systematic review
Mohammed A. S. Khan, Byoung‐Joon Song, Xin Wang, Shams Iqbal, Gyongyi Szabo, Sulie L. Chang
Alcohol, Clinical and Experimental Research.2025; 49(4): 697. CrossRef Toll Like Receptors Promote High Glucose-Induced Vascular Endothelial Cell Dysfunction by Regulating Neutrophil Extracellular Traps Formation
Shirou Wu, Yahui Chen, Xiuming Jin, Jiayun Yu, Xueping Chen, Ting Wan
Inflammation.2025;[Epub] CrossRef Regulatory role of gut microbiota in immunotherapy of hepatocellular carcinoma
Jiajia Du, Yan Guan, Erlei Zhang
Hepatology International.2025; 19(3): 507. CrossRef Food additive β-caryophyllene mitigates alcoholic steatohepatitis by dual modulation of inflammation and lipid metabolism: a diet-based intervention strategy
Jun-Liang Yang, Zhi-Hong Zhang, Xue-Li Jiang, Si-Qi Wang, Yan-Ling Wu, Ji-Xing Nan, Li-Hua Lian
Food & Function.2025; 16(13): 5393. CrossRef Dietary yeast extract prevents alcoholic liver disease in mice
via correcting gut dysbiosis and improving intestinal barrier function
Hao Han, Lei Tian, Yajing Dong, Yanyang Han, Xiaoman Wang, Qian Cheng, Haibo Zhang, Yan Zhang
Food Science and Human Wellness.2025; 14(6): 9250146. CrossRef Unveiling the covert interaction between gut microbiota and neutrophils to drive colorectal cancer metastasis
Peiliang Shen, Peng Cheng, Yanan Li, Gangfan Zong, Rui Deng, Cheng Qian, Yang Zhao, Zhonghong Wei, Yin Lu
European Journal of Pharmacology.2024; 962: 176217. CrossRef Toxoplasma gondii-induced neutrophil extracellular traps are relevant to glycolysis, TLR2, and TLR4 MAPK signaling pathway in goats
Zha Jin, Qinqin Jin, Meiyi Chen, Wei Liu, Hongrong Hong, Yuqian Jiang, Xinxin Gao, Yuxiao Qian, Zedong Wang, Quan Liu, Zhengkai Wei
Parasitology Research.2024;[Epub] CrossRef γδ T Cells: A Game Changer in the Future of Hepatocellular Carcinoma Immunotherapy
Stavros P. Papadakos, Konstantinos Arvanitakis, Ioanna E. Stergiou, Maria-Loukia Koutsompina, Georgios Germanidis, Stamatios Theocharis
International Journal of Molecular Sciences.2024; 25(3): 1381. CrossRef The causal correlation between gut microbiota abundance and pathogenesis of cervical cancer: a bidirectional mendelian randomization study
Hua Yang
Frontiers in Microbiology.2024;[Epub] CrossRef Platelets in Alcohol-Associated Liver Disease: Interaction With Neutrophils
Juan Wang, Xianda Wang, Haodong Peng, Zijian Dong, Suthat Liangpunsakul, Li Zuo, Hua Wang
Cellular and Molecular Gastroenterology and Hepatology.2024; 18(1): 41. CrossRef An integrated network pharmacology approach reveals that Ampelopsis grossedentata improves alcoholic liver disease via TLR4/NF-κB/MLKL pathway
Ping Qiu, Ai Mi, Chunlan Hong, Shuo Huang, Qing Ma, Qihan Luo, Jiang Qiu, He Jiang, Yufan Chen, Fangming Chen, Honghao Yan, Jinkai Zhao, Yu Kong, Yu Du, Changyu Li, Desong Kong, Thomas Efferth, Dayong Lou
Phytomedicine.2024; 132: 155658. CrossRef Expansion of effector regulatory T cells in steroid responders of severe alcohol-associated hepatitis
Min Woo Kang, Soon Kyu Lee, Eun Ji Jang, Jong Geun Park, Deok Hwa Seo, Ji Won Han, Jae Sung Yoo, Jung Hyun Kwon, Soon Woo Nam, Jeong Won Jang, Jong Young Choi, Seung Kew Yoon, Pil Soo Sung
Liver Transplantation.2024; 30(9): 877. CrossRef Imaging and Therapy of Tumors Based on Neutrophil Extracellular Traps
Yongwei Hao, Dalin Liu, Kaiyuan Wang, Qian Liu, Hongli Chen, Shenglu Ji, Dan Ding
Small Science.2024;[Epub] CrossRef Understanding gut dysbiosis for hepatocellular carcinoma diagnosis and treatment
Jingjing Yu, Xiaoping Chen, Xiangliang Yang, Bixiang Zhang
Trends in Endocrinology & Metabolism.2024; 35(11): 1006. CrossRef Timing, initiation and function: An in-depth exploration of the interaction network among neutrophil extracellular traps related genes in acute pancreatitis
Haoyu Zhang, Zheng Wang, Jie Li, Yuchen Jia, Fei Li
International Immunopharmacology.2024; 141: 112923. CrossRef Interaction between intratumoral microbiota and neutrophils influences tumor progression
Mengyuan Hu
American Journal of Clinical and Experimental Immunology.2024; 13(5): 233. CrossRef Alcohol-related liver disease (ALD): current perspectives on pathogenesis, therapeutic strategies, and animal models
Xiao Hong, Shuo Huang, He Jiang, Qing Ma, Jiang Qiu, Qihan Luo, Chunlu Cao, Yiyang Xu, Fuzhe Chen, Yufan Chen, Chunfeng Sun, Haozhe Fu, Yiming Liu, Changyu Li, Fangming Chen, Ping Qiu
Frontiers in Pharmacology.2024;[Epub] CrossRef G-CSF exacerbates liver injury in a mouse model of autoimmune hepatitis
Yi Shen, Yifeng Liu, Kexin Yu, Mengyi Shen, Li Yang
Journal of Hepatology.2023; 79(1): e29. CrossRef Structure and hepatoprotective activity of Usp10/NF-κB/Nrf2 pathway-related Morchella esculenta polysaccharide
Shanshan Teng, Yongfeng Zhang, Xinghui Jin, Yanfeng Zhu, Lanzhou Li, Xiaowei Huang, Di Wang, Zhe Lin
Carbohydrate Polymers.2023; 303: 120453. CrossRef Neutrophil extracellular traps in tumor progression and immunotherapy
Meina Yan, Yifeng Gu, Hongxia Sun, Qinghong Ge
Frontiers in Immunology.2023;[Epub] CrossRef The Role of TLR4 in the Immunotherapy of Hepatocellular Carcinoma: Can We Teach an Old Dog New Tricks?
Stavros P. Papadakos, Konstantinos Arvanitakis, Ioanna E. Stergiou, Vasileios Lekakis, Spyridon Davakis, Maria-Ioanna Christodoulou, Georgios Germanidis, Stamatios Theocharis
Cancers.2023; 15(10): 2795. CrossRef Loss of toll-like receptor 5 potentiates spontaneous hepatocarcinogenesis in farnesoid X receptor–deficient mice
Rachel M. Golonka, Beng San Yeoh, Piu Saha, Amira Gohara, Ramakumar Tummala, Stanislaw Stepkowski, Amit K. Tiwari, Bina Joe, Frank J. Gonzalez, Andrew T. Gewirtz, Matam Vijay-Kumar
Hepatology Communications.2023;[Epub] CrossRef The role of neutrophil extracellular traps and proinflammatory damage-associated molecular patterns in idiopathic inflammatory myopathies
Wenlan Ma, Jiarui Zhu, Ling Bai, Peipei Zhao, Feifei Li, Sigong Zhang
Clinical and Experimental Immunology.2023; 213(2): 202. CrossRef Fusobacterium nucleatum-triggered neutrophil extracellular traps facilitate colorectal carcinoma progression
Xuehua Kong, Yu Zhang, Linwei Xiang, Yan You, Yaqian Duan, Yuqing Zhao, Shue Li, Rui Wu, Jiangbo Zhang, Lan Zhou, Liang Duan
Journal of Experimental & Clinical Cancer Research.2023;[Epub] CrossRef Advancements in the Alcohol-Associated Liver Disease Model
Lin Zhu, Hai-Di Li, Jie-Jie Xu, Juan-Juan Li, Miao Cheng, Xiao-Ming Meng, Cheng Huang, Jun Li
Biomolecules.2022; 12(8): 1035. CrossRef Emerging Role of Neutrophil Extracellular Traps in Gastrointestinal Tumors: A Narrative Review
Yujun Zhang, Jingjing Song, Yiwei Zhang, Ting Li, Jie Peng, Haonan Zhou, Zhen Zong
International Journal of Molecular Sciences.2022; 24(1): 334. CrossRef
|