Non-alcoholic fatty liver disease increases risk of carotid atherosclerosis and ischemic stroke: An updated meta-analysis with 135,602 individuals
Ansel Shao Pin Tang, Kai En Chan, Jingxuan Quek, Jieling Xiao, Phoebe Tay, Margaret Teng, Keng Siang Lee, Snow Yunni Lin, May Zin Myint, Benjamin Tan, Vijay K Sharma, Darren Jun Hao Tan, Wen Hui Lim, Apichat Kaewdech, Daniel Huang, Nicholas WS Chew, Mohammad Shadab Siddiqui, Arun J Sanyal, Mark Muthiah, Cheng Han Ng
Clin Mol Hepatol. 2022;28(3):483-496.   Published online 2022 Mar 2     DOI: https://doi.org/10.3350/cmh.2021.0406
Citations to this article as recorded by Crossref logo
NAFLD and NAFLD-related HCC in Asia: Burden and Surveillance
Jia H. Koh, Meng Wang, Hiroyuki Suzuki, Mark Muthiah, Cheng H. Ng, Daniel Q. Huang
Journal of Clinical and Experimental Hepatology.2024; 14(1): 101213.     CrossRef
Donor Diabetes and Steatosis Affects Recipient Survival Following Liver Transplantation Based on Etiology of Liver Cirrhosis
Wen Hui Lim, Cheng Han Ng, Darren Jun Hao Tan, Jieling Xiao, Clarissa Elysia Fu, Christen Ong, Benjamin Koh, Charlotte Chung, Shi Ni Tan, Zhen Yu Wong, Kimberly Mitchell, Ayana Andrews Joseph, Michael Tseng, Nicholas Syn, Lung Yi Mak, James Fung, Daniel Q
Transplantation.2024; 108(2): 473.     CrossRef
Liver Enzymes and the Risk of Stroke among the General Japanese Population: A Prospective Cohort Study
Ahmed Arafa, Yoshihiro Kokubo, Rena Kashima, Chisa Matsumoto, Masatoshi Koga
Cerebrovascular Diseases.2024; 53(3): 252.     CrossRef
Longitudinal Outcomes Associated With Metabolic Dysfunction-Associated Steatotic Liver Disease: A Meta-analysis of 129 Studies
Kai En Chan, Elden Yen Hng Ong, Charlotte Hui Chung, Christen En Ya Ong, Benjamin Koh, Darren Jun Hao Tan, Wen Hui Lim, Jie Ning Yong, Jieling Xiao, Zhen Yu Wong, Nicholas Syn, Apichat Kaewdech, Margaret Teng, Jiong-Wei Wang, Nicholas Chew, Dan Yock Young
Clinical Gastroenterology and Hepatology.2024; 22(3): 488.     CrossRef
Correlation Study of Exosome miRNA-126 in Patients with Metabolic Related Fatty Liver Disease after Ischemic Stroke
雪 韩
Advances in Clinical Medicine.2024; 14(01): 301.     CrossRef
Appendicular Skeletal Muscle Mass to Visceral Fat Area Ratio Predicts Hepatic Morbidities
Eugene Han, Yong-ho Lee, Sang Hoon Ahn, Bong-Soo Cha, Seung Up Kim, Byung-Wan Lee
Gut and Liver.2024; 18(3): 509.     CrossRef
Type 2 diabetes mellitus and cardiometabolic outcomes in metabolic dysfunction-associated steatotic liver disease population
Nicholas W.S. Chew, Xin Hui Pan, Bryan Chong, Chanchal Chandramouli, Mark Muthiah, Carolyn S.P. Lam
Diabetes Research and Clinical Practice.2024; 211: 111652.     CrossRef
Cardiovascular morbidity and mortality in lean vs. non-lean MASLD: A comprehensive meta-analysis
Nso Nso, Damla Mergen, Mashaal Ikram, Victor Macrinici, Kifah Hussain, Kevin Lee, Derek Ugwendum, Mia Trimingham, Senthil Balasubramanian, Riya Sam, Basile Njei
Current Problems in Cardiology.2024; 49(6): 102569.     CrossRef
Association between severity of nonalcoholic fatty liver disease and major adverse cardiovascular events in patients assessed by coronary computed tomography angiography
Rongchao Shi, Xuemei Li, Kui Sun, Fangyuan Liu, Bing Kang, Yilin Wang, Ying Wang, Baosen Zhu, Xinya Zhao, Zhiqiang Liu, Ximing Wang
BMC Cardiovascular Disorders.2024;[Epub]     CrossRef
Complete alcohol abstinence increases the risk of NAFLD but not severity. A population analysis with transient elastography
Jieling Xiao, Cheng Han Ng, Kai En Chan, Ansel Shao Pin Tang, Readon Teh, Abel Ho Zhi Ling, Jie Ning Yong, Wen Hui Lim, Darren Jun Hao Tan, Caitlyn Tan, Khin Maung Win, Aung Hlaing Bwa, Nicholas W. S. Chew, Daniel Huang, Yock Young Dan, Mazen Noureddin, M
Scandinavian Journal of Gastroenterology.2023; 58(1): 76.     CrossRef
Comparative Burden of Metabolic Dysfunction in Lean NAFLD vs Non-lean NAFLD - A Systematic Review and Meta-analysis
Ansel Tang, Cheng Han Ng, Poh Hui Phang, Kai En Chan, Yip Han Chin, Clarissa Elysia Fu, Rebecca Wenling Zeng, Jieling Xiao, Darren Jun Hao Tan, Jingxuan Quek, Wen Hui Lim, Lung Yi Mak, Jiong-wei Wang, Nicholas W.S. Chew, Nicholas Syn, Daniel Q. Huang, Moh
Clinical Gastroenterology and Hepatology.2023; 21(7): 1750.     CrossRef
Metabolic dysfunction associated fatty liver disease identifies subjects with cardiovascular risk better than non‐alcoholic fatty liver disease
Ho Soo Chun, Minjong Lee, Jae Seung Lee, Hye Won Lee, Beom Kyung Kim, Jun Yong Park, Do Young Kim, Sang Hoon Ahn, Yong‐Ho Lee, Ji‐Hye Kim, Seung Up Kim
Liver International.2023; 43(3): 608.     CrossRef
A Meta-analysis on Associated Risk of Mortality in Nonalcoholic Fatty Liver Disease
Clarissa Elysia Fu, Cheng Han Ng, Jie Ning Yong, Kai En Chan, Jieling Xiao, Benjamin Nah, Shirley Huey Shin Bong, Khin Maung Win, Aung Hlaing Bwa, Wen Hui Lim, Darren Jun Hao Tan, Rebecca Wenling Zeng, Nicholas Chew, Margaret L.P. Teng, Mohammad Shadab Si
Endocrine Practice.2023; 29(1): 33.     CrossRef
Hepatic, Extra-hepatic Outcomes and Causes of Mortality in NAFLD – An Umbrella Overview of Systematic Review of Meta-Analysis
Jieling Xiao, Cheng Han Ng, Kai En Chan, Clarissa Fu, Phoebe Tay, Jie Ning Yong, Wen Hui Lim, Darren Jun Hao Tan, Nicholas Syn, Zhen Yu Wong, Michael Tseng, Nicholas Chew, Daniel Q. Huang, Yock Yong Dan, Vincent Wai-Sun Wong, Rohit Loomba, Mohammad S. Sid
Journal of Clinical and Experimental Hepatology.2023; 13(4): 656.     CrossRef
Risk Stratification for Sarcopenic Obesity in Subjects With Nonalcoholic Fatty Liver Disease
Ho Soo Chun, Minjong Lee, Hye Ah Lee, Sejin Lee, Soyeon Kim, Ye Jun Jung, Chaewon Lee, Hyoeun Kim, Han Ah Lee, Hwi Young Kim, Kwon Yoo, Tae Hun Kim, Sang Hoon Ahn, Seung Up Kim
Clinical Gastroenterology and Hepatology.2023; 21(9): 2298.     CrossRef
Hepatic steatosis and advanced hepatic fibrosis are independent predictors of long‐term mortality in acute myocardial infarction
YipHan Chin, Jieyu Lim, Gwyneth Kong, Cheng Han Ng, Rachel Goh, Mark Muthiah, Anurag Mehta, Bryan Chong, Chaoxing Lin, Kai En Chan, William Kong, Kian Keong Poh, Roger Foo, Ping Chai, Tiong‐Cheng Yeo, Adrian F. Low, Chi Hang Lee, Huay Cheem Tan, Mark Yan‐
Diabetes, Obesity and Metabolism.2023; 25(4): 1032.     CrossRef
Examining the interim proposal for name change to steatotic liver disease in the US population
Cheng Han Ng, Kai En Chan, Mark Muthiah, Caitlyn Tan, Phoebe Tay, Wen Hui Lim, Darren Jun Hao Tan, Clarissa Elysia Fu, Jie Ning Yong, Zhen Yu Wong, Benjamin Koh, Nicholas WS Chew, Nicholas Syn, Daniel Q. Huang, Yock Young Dan, Mohammad S. Siddiqui, Arun J
Hepatology.2023; 77(5): 1712.     CrossRef
The prognostic value of including non‐alcoholic fatty liver disease in the definition of metabolic syndrome
Clarissa Elysia Fu, Jie Ning Yong, Cheng Han Ng, Benjamin Nah, Nicholas W. S. Chew, Yip Han Chin, Gwyneth Kong, Darren Jun Hao Tan, Wen Hui Lim, Lincoln Kai En Lim, Rebecca Wenling Zeng, Asim Shabbir, Eunice X. X. Tan, Daniel Q. Huang, Chin Meng Khoo, Moh
Alimentary Pharmacology & Therapeutics.2023; 57(9): 979.     CrossRef
Safety and tolerability of obeticholic acid in chronic liver disease: a pooled analysis of 1878 individuals
Cheng Han Ng, Ansel Shao Pin Tang, Jieling Xiao, Zhen Yu Wong, Jie Ning Yong, Clarissa E. Fu, Rebecca W. Zeng, Caitlyn Tan, Gabriel Hong Zhe Wong, Margaret Teng, Douglas Chee, Darren Jun Hao Tan, Kai En Chan, Daniel Q. Huang, Nicholas W.S. Chew, Benjamin
Hepatology Communications.2023; 7(3): e0005.     CrossRef
Extrahepatic Outcomes of Nonalcoholic Fatty Liver Disease
Angelo Armandi, Elisabetta Bugianesi
Clinics in Liver Disease.2023; 27(2): 239.     CrossRef
The global burden of metabolic disease: Data from 2000 to 2019
Nicholas W.S. Chew, Cheng Han Ng, Darren Jun Hao Tan, Gwyneth Kong, Chaoxing Lin, Yip Han Chin, Wen Hui Lim, Daniel Q. Huang, Jingxuan Quek, Clarissa Elysia Fu, Jieling Xiao, Nicholas Syn, Roger Foo, Chin Meng Khoo, Jiong-Wei Wang, Georgios K. Dimitriadis
Cell Metabolism.2023; 35(3): 414.     CrossRef
Risk Scores for Prediction of Major Cardiovascular Events in Non-Alcoholic Fatty Liver Disease: A No Man’s Land?
Liliana Gheorghe, Roxana Nemteanu, Andreea Clim, Gina Eosefina Botnariu, Irina Iuliana Costache, Alina Plesa
Life.2023; 13(4): 857.     CrossRef
Nonalcoholic fatty liver disease and non-liver comorbidities
Richie Manikat, Mindie H. Nguyen
Clinical and Molecular Hepatology.2023; 29(Suppl): s86.     CrossRef
Integrated bioinformatics and machine-learning screening for immune-related genes in diagnosing non-alcoholic fatty liver disease with ischemic stroke and RRS1 pan-cancer analysis
Huayan Bao, Jianwen Li, Boyang Zhang, Ju Huang, Danke Su, Lidong Liu
Frontiers in Immunology.2023;[Epub]     CrossRef
General Public’s knowledge, awareness, and perception of Cardiometabolic diseases: data from a Singapore study population
Vickram Vijay Anand, Rachel Sze Jen Goh, Benjamin Nah, Sky Wei Chee Koh, Jieyu Lim, Nicholas W. S. Neo, Jocelyn Chew, Yuan Ying Lee, Yip Han Chin, Bryan Chong, Gwyneth Kong, Bryan Tan, Zhiwen Low, Chin Meng Khoo, Lay Hoon Goh, Poay Huan Loh, Ping Chai, Ma
Frontiers in Medicine.2023;[Epub]     CrossRef
The regulatory role of metabolic organ-secreted factors in the nonalcoholic fatty liver disease and cardiovascular disease
Li Qin, Junru Wu, Xuejing Sun, Xuewei Huang, Wei Huang, Chunyan Weng, Jingjing Cai
Frontiers in Cardiovascular Medicine.2023;[Epub]     CrossRef
Supplementation of Lactobacillus plantarum ATCC14917 mitigates non-alcoholic fatty liver disease in high-fat-diet-fed rats
Xingjian Wen, Hejing Liu, Xiaoling Luo, Li Lui, Jiuyu Fan, Yajing Xing, Jia Wang, Xingfang Qiao, Na Li, Guixue Wang
Frontiers in Microbiology.2023;[Epub]     CrossRef
An international multidisciplinary consensus statement on MAFLD and the risk of CVD
Xiao-Dong Zhou, Giovanni Targher, Christopher D. Byrne, Virend Somers, Seung Up Kim, C. Anwar A. Chahal, Vincent Wai-Sun Wong, Jingjing Cai, Michael D. Shapiro, Mohammed Eslam, Philippe Gabriel Steg, Ki-Chul Sung, Anoop Misra, Jian-Jun Li, Carlos Brotons,
Hepatology International.2023; 17(4): 773.     CrossRef
Editorial: The heart of NAFLD
Nicholas W. S. Chew, Shankar Kannan, Bryan Chong, Yiphan Chin, Mark Muthiah
Frontiers in Medicine.2023;[Epub]     CrossRef
Ultrasound Score of Liver Steatosis Severity in the Diagnosis of Peripheral Arterial Atherosclerosis in Patients with Nonalcoholic Fatty Liver Disease
A. S. Kuznetsova, A. I. Dolgushina, V. V. Pospelov, T. A. Sokolova, E. V. Lebedev, V. V. Genkel
The Russian Archives of Internal Medicine.2023; 13(3): 196.     CrossRef
MAFLD might be better in identifying subjects with sarcopenia or cardiovascular risk than NAFLD: A nationwide study
Eugene Han, Ho Soo Chun, Yong‐ho Lee, Jae Seung Lee, Hye Won Lee, Beom Kyung Kim, Jun Yong Park, Do Young Kim, Byung‐Wan Lee, Eun Seok Kang, Bong‐Soo Cha, Sang Hoon Ahn, Seung Up Kim
Journal of Gastroenterology and Hepatology.2023; 38(9): 1598.     CrossRef
Nonalcoholic Fatty Liver Disease and Cardiovascular Disease: Clinical Evidence and a Mechanistic Review
飏 屈
Advances in Clinical Medicine.2023; 13(08): 12753.     CrossRef
High-density lipoproteins and non-alcoholic fatty liver disease
Menno Hoekstra, Miranda Van Eck
Atherosclerosis Plus.2023; 53: 33.     CrossRef
Hepatic Involvement across the Metabolic Syndrome Spectrum: Non-Invasive Assessment and Risk Prediction Using Machine Learning
Adelaida Solomon, Călin Remus Cipăian, Mihai Octavian Negrea, Adrian Boicean, Romeo Mihaila, Corina Beca, Mirela Livia Popa, Sebastian Mihai Grama, Minodora Teodoru, Bogdan Neamtu
Journal of Clinical Medicine.2023; 12(17): 5657.     CrossRef
Association of fat-to-muscle ratio with non-alcoholic fatty liver disease: a single-centre retrospective study
Fengqin Yan, Guqiao Nie, Nianli Zhou, Meng Zhang, Wen Peng
BMJ Open.2023; 13(10): e072489.     CrossRef
Lack of association between nonalcoholic fatty liver disease and intracerebral hemorrhage: A community-based cohort study
Jianwei Wu, Jiahuan Guo, Anxin Wang, Yijun Zhang, Shouling Wu, Xingquan Zhao
Journal of Clinical Neuroscience.2023; 118: 7.     CrossRef
Ankle systolic pressure index in non-diabetic non-alcoholic fatty liver disease: A case-control study
Said Taharboucht, Rachida Guermaz, Mansour Brouri, Lamia Bengherbia, Ahcene Chibane
JMV-Journal de Médecine Vasculaire.2023; 48(5-6): 154.     CrossRef
Non-alcoholic fatty liver disease and risk of cardiovascular diseases: clinical association, pathophysiological mechanisms, and management
Rong Yang, Jian-Gao Fan
Cardiology Plus.2023; 8(4): 217.     CrossRef
Clinical Management of Non-alcoholic Steatohepatitis and the Role of the Cardiologist
Carlos Millán-Rodríguez, Carlos Palacios Castelló Palacios Castelló, María de Regla Caballero-Valderrama, Gonzalo Barón Esquivias
European Cardiology Review.2023;[Epub]     CrossRef
Nonalcoholic fatty liver disease and cardiovascular diseases: A Mendelian randomization study
Hexiang Peng, Siyue Wang, Mengying Wang, Ying Ye, Enci Xue, Xi Chen, Xueheng Wang, Meng Fan, Wenjing Gao, Xueying Qin, Yiqun Wu, Dafang Chen, Jin Li, Yonghua Hu, Li Wang, Tao Wu
Metabolism.2022; 133: 155220.     CrossRef
Does nonalcoholic fatty liver disease predispose patients to carotid arteriosclerosis and ischemic stroke?
Qian Jin, Rui-Xu Yang, Jian-Gao Fan
Clinical and Molecular Hepatology.2022; 28(3): 473.     CrossRef
Living in the non‐alcoholic fatty liver disease silent epidemic: a qualitative systematic review of patients' perspectives
Cheng Han Ng, Wen Hui Lim, Yip Han Chin, Jie Ning Yong, Rebecca Wenling Zeng, Kai En Chan, Darren Jun Hao Tan, Clarissa Elysia Fu, Ansel Shao Pin Tang, Lay Hoon Goh, Kamala Devi, Nicholas W. S. Chew, Lung‐Yi Loey Mak, Nobuharu Tamaki, Daniel Q. Huang, Maz
Alimentary Pharmacology & Therapeutics.2022; 56(4): 570.     CrossRef
Hypertension is prevalent in non-alcoholic fatty liver disease and increases all-cause and cardiovascular mortality
Cheng Han Ng, Zhen Yu Wong, Nicholas W. S. Chew, Kai En Chan, Jieling Xiao, Nilofer Sayed, Wen Hui Lim, Darren Jun Hao Tan, Ryan Wai Keong Loke, Phoebe Wen Lin Tay, Jie Ning Yong, Gywneth Kong, Daniel Q. Huang, Jiong-Wei Wang, Mark Chan, Mayank Dalakoti,
Frontiers in Cardiovascular Medicine.2022;[Epub]     CrossRef
Statins decrease overall mortality and cancer related mortality but are underutilized in NAFLD: a longitudinal analysis of 12,538 individuals
Cheng Han Ng, Margaret LP Teng, Nicholas WS Chew, Kai En Chan, Jie Ning Yong, Jingxuan Quek, Darren Jun Hao Tan, Wen Hui Lim, Gabriel Sheng Jie Lee, Jessica Wong, Apichat Kaewdech, Daniel Q Huang, Jiongwei Wang, Mark Y Chan, Mazen Noureddin, Mohammad Shad
Expert Review of Gastroenterology & Hepatology.2022; 16(9): 895.     CrossRef
Nonalcoholic fatty liver disease and risk of intracerebral hemorrhage
Jianwei Wu, Jiahuan Guo, Anxin Wang, Yijun Zhang, Shouling Wu, Yanfang Liu, Xingquan Zhao
Nutrition, Metabolism and Cardiovascular Diseases.2022; 32(11): 2561.     CrossRef
Depression in non-alcoholic fatty liver disease is associated with an increased risk of complications and mortality
Cheng Han Ng, Jieling Xiao, Nicholas W. S. Chew, Yip Han Chin, Kai En Chan, Jingxuan Quek, Wen Hui Lim, Darren Jun Hao Tan, Ryan Wai Keong Loke, Caitlyn Tan, Ansel Shao Pin Tang, Xin Lei Goh, Benjamin Nah, Nicholas Syn, Dan Yock Young, Nobuharu Tamaki, Da
Frontiers in Medicine.2022;[Epub]     CrossRef
Modulatory effect of camel milk on intestinal microbiota of mice with non-alcoholic fatty liver disease
Shiqi Hao, Liang Ming, Yafei Li, Haodi Lv, Lin Li, Tuyatsetseg Jambal, Rimutu Ji
Frontiers in Nutrition.2022;[Epub]     CrossRef
High prevalence of non-alcoholic fatty liver disease in patients with a first episode of acute ischemic stroke. Impact on disability and death
Lidia Canillas, Agnes Soriano-Varela, Ana Rodríguez-Campello, Eva Giralt-Steinhauer, Elisa Cuadrado-Godia, Teresa Broquetas
Frontiers in Endocrinology.2022;[Epub]     CrossRef