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"Metabolic syndrome"

Letter to the Editor

Reply to Correspondence

  • 4,306 View
  • 30 Download

Correspondence

Citations

Citations to this article as recorded by  Crossref logo
  • Advancing metabolic risk profiling in chronic hepatitis B: Reply to correspondence on “Metabolic health in antiviral era of chronic hepatitis B”
    Shang-Chin Huang, Jia-Horng Kao
    Clinical and Molecular Hepatology.2026; 32(1): e117.     CrossRef
  • 3,679 View
  • 15 Download
  • Crossref

Editorials

Citations

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  • Correspondence to editorial 2 on “Impacts of metabolic syndrome diseases on long-term outcomes of chronic hepatitis B patients treated with nucleos(t)ide analogues”
    Rui Huang, Mindie H. Nguyen
    Clinical and Molecular Hepatology.2026; 32(1): e85.     CrossRef
  • 3,670 View
  • 58 Download
  • 1 Web of Science
  • Crossref

Citations

Citations to this article as recorded by  Crossref logo
  • Advancing metabolic risk profiling in chronic hepatitis B: Reply to correspondence on “Metabolic health in antiviral era of chronic hepatitis B”
    Shang-Chin Huang, Jia-Horng Kao
    Clinical and Molecular Hepatology.2026; 32(1): e117.     CrossRef
  • Correspondence to editorial 1 on “Impacts of metabolic syndrome diseases on long-term outcomes of chronic hepatitis B patients treated with nucleos(t)ide analogues”
    Rui Huang, Mindie H. Nguyen
    Clinical and Molecular Hepatology.2026; 32(1): e83.     CrossRef
  • Steatosis paradox: Unraveling pathways of suppressive effect of hepatic steatosis on hepatitis B virus
    Shang-Chin Huang, Jia-Horng Kao
    Biomedical Journal.2026; 49(3): 100969.     CrossRef
  • The Chronic Hepatitis B and Metabolic Dysfunction-Associated Steatotic Liver Disease Paradox: Friend or Foe?
    Shang-Chin Huang, Tai-Chung Tseng
    Gut and Liver.2026; 20(3): 350.     CrossRef
  • Insulin Resistance and Hepatocellular Carcinoma Development in Chronic Hepatitis B Patients Under Antiviral Therapy
    Dong Hyun Sinn, Kyung-Ah Kim, Jung Il Lee, Geum-Youn Gwak
    Journal of Korean Medical Science.2026;[Epub]     CrossRef
  • 5,255 View
  • 50 Download
  • 2 Web of Science
  • Crossref

Letter to the Editor

What is new in the 2024 Chinese guidelines for fatty liver disease?
Rui-Xu Yang, Vincent Wai-Sun Wong, Jian-Gao Fan
Clin Mol Hepatol 2025;31(3):e239-e246.
Published online January 21, 2025
DOI: https://doi.org/10.3350/cmh.2024.1165

Citations

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  • Comparison of the identification and practicability of non-invasive diagnostic indicators under NAFLD, MAFLD and MASLD in China: a cross-sectional study
    Xin-Yun Tan, Hui-Hui Zou, Xinjuan Huang, Man-Jie Guo, Ruo-Ling Yu, Xue-Lian Liu, Ting Peng, Xuan Yang, Chun-Xiang Qin
    BMJ Open.2026; 16(4): e094809.     CrossRef
  • 11,197 View
  • 104 Download
  • 1 Web of Science
  • Crossref

Original Article

Steatotic liver disease

Metabolic dysfunction-associated steatotic liver disease exhibits sex-specific microbial heterogeneity within intestinal compartments
Carlos Jose Pirola, Maria Silvina Landa, Mariano Schuman, Silvia Inés García, Adrian Salatino, Silvia Sookoian
Clin Mol Hepatol 2025;31(1):179-195.
Published online October 11, 2024
DOI: https://doi.org/10.3350/cmh.2024.0359
Background/Aims
Evidence suggests that the gastrointestinal microbiome plays a significant role in the biology of metabolic dysfunction-associated steatotic liver disease (MASLD). However, it remains unclear whether disparities in the gut microbiome across intestinal tissular compartments between the sexes lead to MASLD pathogenesis.
Methods
Sex-specific analyses of microbiome composition in two anatomically distinct regions of the gut, the small intestine and colon, were performed using an experimental model of MASLD. The study involved male and female spontaneously hypertensive rats and the Wistar-Kyoto control rat strain, which were fed either a standard chow diet or a high-fat diet for 12 weeks to induce MASLD (12 rats per group). High-throughput 16S sequencing was used for microbiome analysis.
Results
There were significant differences in the overall microbiome composition of male and female rats with MASLD, including variations in topographical gut regions. The beta diversity of the jejunal and colon microbiomes was higher in female rats than in male rats (PERMANOVA p-value=0.001). Sex-specific analysis and discriminant features using LEfSe showed considerable variation in bacterial abundance, along with distinct functional properties, in the jejunum and colon of animals with MASLD. Significantly elevated levels of lipopolysaccharide and protein expression of Toll-like receptor 4 were observed in the livers of male rats with MASLD compared with their female counterparts.
Conclusions
This study uncovered sexual dimorphism in the gut microbiome of MASLD and identified microbial heterogeneity within intestinal compartments. Insights into sex-specific variations in gut microbiome composition could facilitate customised treatment strategies.

Citations

Citations to this article as recorded by  Crossref logo
  • Sex and gender differences in metabolic dysfunction-associated liver disease
    Rishitha Penmetsa, Sasha Kapil, Lisa B. VanWagner
    Indian Journal of Gastroenterology.2026; 45(2): 192.     CrossRef
  • New Definition, New Point of View: Sex and Gender Interpretation of MASLD—Interpretation of Guidelines and Review of the Literature
    Massimo De Luca, Rita Verdoliva, Anna Lombardi, Antonio Giorgio
    Gastroenterology Insights.2026; 17(1): 7.     CrossRef
  • The Gut–Liver Axis in MASLD: From Host–Microbiome Crosstalk to Precision Therapeutics
    Ji Zhou, Bowen Zhu, Ziqian Bing, Tingting Wang, Yue Zhao
    Microorganisms.2026; 14(2): 471.     CrossRef
  • Sex-specific dynamics of MASLD reveal early hepatic and extrahepatic metabolic deterioration in females despite long-term protection
    Maria Repollés-de-Dalmau, Anna Marsal-Beltran, Catalina Núñez-Roa, Joan Vendrell, Victòria Ceperuelo-Mallafré, Sonia Fernández-Veledo
    Biology of Sex Differences.2026;[Epub]     CrossRef
  • Sex-specific cardiometabolic phenotypes in MASLD: 3PM-centric stratification and trajectory mapping for proactive risk assessment
    Carlos José Pirola, Luis Diambra, Tomas Fernández Gianotti, Silvia Sookoian
    EPMA Journal.2026; 17(2): 387.     CrossRef
  • Dysregulation of the Gut-Adipose Tissue-Liver Axis: a Possible Mechanism Behind the Relationship Between Metabolic Dysfunction-Associated Steatotic Liver Disease and Type 2 Diabetes
    Susanna Longo, Tommaso Giovanni Rinaldi, Jose Manuel Fernández-Real, Massimo Federici
    Current Diabetes Reports.2026;[Epub]     CrossRef
  • Correspondence to letter to the editor on “Role of amino acids in the regulation of hepatic gluconeogenesis and lipogenesis in metabolic dysfunctionassociated steatotic liver disease”
    Eiji Kakazu, Masaaki Mino, Tatsuya Kanto
    Clinical and Molecular Hepatology.2026; 32(2): e235.     CrossRef
  • MASLD: Prevalence, Mechanisms, and Sex-Based Therapies in Postmenopausal Women
    Ilaria Milani, Marianna Chinucci, Frida Leonetti, Danila Capoccia
    Biomedicines.2025; 13(4): 855.     CrossRef
  • Characteristics of serum bile acid profiles among individuals with metabolic dysfunction-associated steatotic liver disease
    Sheng Lyu, Jiani Yang, Xin Xin, Qinmei Sun, Beiyu Cai, Xin Wang, Ziming An, Jian Sun, Yiyang Hu, Lei Shi, Qin Feng, Xiaojun Gou
    BMC Gastroenterology.2025;[Epub]     CrossRef
  • Gut-Liver Axis: The Role of Intestinal Microbiota and Their Metabolites in the Progression of Metabolic Dysfunction-Associated Steatotic Liver Disease
    Chao Cui, Shuai Gao, Jingfei Shi, Kai Wang
    Gut and Liver.2025; 19(4): 479.     CrossRef
  • Triglyceride-glucose-waist circumference index: A powerful tool for metabolic dysfunction-associated steatotic liver disease
    Bryan Adrian Priego-Parra, Berenice M Román-Calleja, Rocio Gallego-Duran, Jordi Gracia-Sancho, Jose Antonio Velarde Ruiz-Velasco, Jose Maria Remes-Troche
    World Journal of Hepatology.2025;[Epub]     CrossRef
  • Animal models of lean metabolic dysfunction-associated steatotic liver disease (MASLD): bridging pathogenesis and novel drug discovery
    Stavros P. Papadakos, Chara Georgiadou, Eva Kassi, Rallia-Iliana Velliou, Antonios Chatzigeorgiou
    Expert Opinion on Drug Discovery.2025; 20(12): 1683.     CrossRef
  • 7,389 View
  • 206 Download
  • 12 Web of Science
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Review

Steatotic liver disease

Epidemiology of metabolic dysfunction-associated steatotic liver disease
Zobair M. Younossi, Markos Kalligeros, Linda Henry
Clin Mol Hepatol 2025;31(Suppl):S32-S50.
Published online August 19, 2024
DOI: https://doi.org/10.3350/cmh.2024.0431
As the rates of obesity and type 2 diabetes (T2D) continue to increase globally, so does the prevalence of metabolic dysfunction–associated steatotic liver disease (MASLD). Currently, 38% of all adults and 7–14% of children and adolescents have MASLD. By 2040, the MASLD prevalence rate for adults is projected to increase to more than 55%. Although MASLD does not always develop into progressive liver disease, it has become the top indication for liver transplant in the United States for women and those with hepatocellular carcinoma (HCC). Nonetheless, the most common cause of mortality among patients with MASLD remains cardiovascular disease. In addition to liver outcomes (cirrhosis and HCC), MASLD is associated with an increased risk of developing de novo T2D, chronic kidney disease, sarcopenia, and extrahepatic cancers. Furthermore, MASLD is associated with decreased health-related quality of life, decreased work productivity, fatigue, increased healthcare resource utilization, and a substantial economic burden. Similar to other metabolic diseases, lifestyle interventions such as a heathy diet and increased physical activity remain the cornerstone of managing these patients. Although several obesity and T2D drugs are available to treat co-morbid disease, resmetirom is the only MASH-targeted medication for patients with stage 2–3 fibrosis that has approved by the Food and Drug Administration for use in the United States. This review discusses MASLD epidemiology and its related risk factors and outcomes and demonstrates that without further global initiatives, MASLD incidence could continue to increase.

Citations

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    Marialena Mouzaki
    Hepatology.2026; 83(3): 445.     CrossRef
  • Association between dietary amino acid intake and the risk of metabolic dysfunction-associated steatotic liver disease
    Ruoqi Zhou, Xinrong Zhang, Xinxin Liu, Rui Huang, Yuwei Wang, Dajing Xia, Xue Li, Yihua Wu, Yu Shi
    Journal of Advanced Research.2026; 80: 893.     CrossRef
  • Population perspectives on benefits and harms of screening for metabolic dysfunction–associated steatotic liver disease
    Alina M. Allen, W. Ray Kim, Patrizia Carrieri, Rachel Canning, Fang-Shu Ou, Joanne Benson, Jessica L. Olson, Sudhakar K. Venkatesh, Jiahui Li, Meng Yin, Maysa Eslami, Richard L. Ehman, Jennifer Hunter Berg, Jeffrey V. Lazarus
    Hepatology.2026; 83(2): 362.     CrossRef
  • A Novel Risk Prediction Model for Hepatocellular Carcinoma in MASLD: A Multinational, Multicenter Cohort Study
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    Clinical Gastroenterology and Hepatology.2026; 24(3): 688.     CrossRef
  • The OGT–TFF2 axis mediates intrahepatic crosstalk and MASH pathogenesis
    Lei Zhang, Cuijuan Han, Man Mohan Shrestha, Jiamei Le, Wilhelm K. Berger, Yiheng Huang, Reina Desrouleaux, Eric Wang, Laszlo Nagy, Xiaoyong Yang
    Hepatology.2026; 83(5): 1215.     CrossRef
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    Nicole Ng, Subhanik Purkayastha, Xiaohan Ying, Arun Jesudian, Russell Rosenblatt
    Digestive Diseases and Sciences.2026; 71(2): 486.     CrossRef
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    Francesca Farina, Aurgho Datta, Suzanne N. Morin, Sahar Saeed, Bertrand Lebouche, Giovanni Guaraldi, Salvatore Petta, Giada Sebastiani
    HIV Medicine.2026; 27(1): 4.     CrossRef
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    Sami Akbulut, Tevfik Tolga Sahin
    European Journal of Gastroenterology & Hepatology.2026; 38(3): 243.     CrossRef
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    Jakeline Liara Teleken, Ana Paula Farina Rosolen, Joseane Morari, Sandra Lucinei Balbo, Rosane Aparecida Ribeiro, Maria Lúcia Bonfleur
    Naunyn-Schmiedeberg's Archives of Pharmacology.2026; 399(3): 3589.     CrossRef
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    Michael Ndaa, Prashant K. Pandya, Jordan Swensson, Niharika Samala, Saima Ajaz, Deepak Joshi, Walid S. Ayoub, Fatih Akisik
    Endocrine Practice.2026; 32(2): 258.     CrossRef
  • Semaglutide, the first approved GLP-1 receptor agonist for the management of metabolic dysfunction-associated steatohepatitis
    Chrysoula Boutari, Michael A. Hill, Christos S. Mantzoros
    Metabolism.2026; 174: 156397.     CrossRef
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    Yuan Qiao, Yijia Zhang, Cuiting Sun, Qi Jin, Peng Qu, Zecheng Li, Yang Qiu, Hua Meng, Dantao Peng, Liang Peng
    Metabolism.2026; 174: 156416.     CrossRef
  • The Bubble-Destruction Curve Obtained Using Contrast-Enhanced Ultrasound is Useful for Assessing Liver Fibrosis and Identifying At-risk MASH in Patients With MASLD
    Noritaka Wakui, Yu Ogino, Naohisa Kamiyama, Takuma Oguri, Tomoya Uchimura, Takahide Kudo, Kenichi Maruyama, Hideki Nagumo, Naoyuki Yoshimine, Kunihide Mouri, Kojiro Kobayashi, Takanori Mukozu, Teppei Matsui, Hidenari Nagai, Yoshinori Igarashi, Takahisa Ma
    Ultrasound in Medicine & Biology.2026; 52(1): 237.     CrossRef
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    Masashi Hirooka, Teruki Miyake, Ryo Yano, Yoshiko Nakamura, Yuki Okazaki, Toyoki Shimamoto, Atsushi Yukimoto, Yasunori Yamamoto, Takao Watanabe, Osamu Yoshida, Kana Hirooka, Yoshio Tokumoto, Masanori Abe, Takeru Iwata, Yoichi Hiasa
    Gastro Hep Advances.2026; 5(1): 100806.     CrossRef
  • Diabetes and the liver
    Ebo Dadey, Tiong Yeng Lim, Janine Makaronidis
    Clinical Medicine.2026; 26(1): 100528.     CrossRef
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    Shansen Xu, Xianglei Ma, Lingli Huang, Tingting Yue, Ya'nan Chen
    Lipids.2026; 61(1): 163.     CrossRef
  • Metabolic Dysfunction–Associated Steatotic Liver Disease in Adults
    Herbert Tilg, Salvatore Petta, Norbert Stefan, Giovanni Targher
    JAMA.2026; 335(2): 163.     CrossRef
  • Recognizing the Burden of Metabolic Liver Disease in IBD
    Raseen Tariq, Richard K Sterling
    Inflammatory Bowel Diseases.2026; 32(3): 584.     CrossRef
  • Editorial: Understanding How Social Determinants of Health Impact Mortality in MASLD—Insights From a National Analysis
    Joyce Lui, Yesung Kweon, Mohamed I. Elsaid
    Alimentary Pharmacology & Therapeutics.2026; 63(5): 750.     CrossRef
  • Advances in Incretin‐Based Therapies for MAFLD: Mechanisms and Clinical Evidence
    Wenqi Dong, Haiming Zhang, Shaowei Mu, Shuyi Shi, Junli Zhang, Keshu Xu
    Clinical Pharmacology & Therapeutics.2026; 119(2): 336.     CrossRef
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    Life Sciences.2026; 384: 124092.     CrossRef
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    Food and Chemical Toxicology.2026; 207: 115855.     CrossRef
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    Jakeline Liara Teleken, Leticia Prates Roma, Rosane Aparecida Ribeiro, Alex Rafacho, Maria Lúcia Bonfleur
    Toxicology in Vitro.2026; 111: 106178.     CrossRef
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    Surgery for Obesity and Related Diseases.2026; 22(1): 113.     CrossRef
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    Clinical Gastroenterology and Hepatology.2026; 24(3): 583.     CrossRef
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    Yunheng Li, Minghua Ye, Qiaojun He, Bo Yang, Peihua Luo, Xiaochun Yang
    Phytomedicine.2026; 150: 157614.     CrossRef
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    Journal of Hepatology.2026; 84(3): 655.     CrossRef
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    Scandinavian Journal of Gastroenterology.2026; 61(1): 124.     CrossRef
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    Marie Byenfeldt, Patrik Nasr, Anna Lindam, Christer Grönlund, Mattias Ekstedt, Peter Lundberg, Johan Kihlberg
    European Journal of Radiology.2026; 195: 112602.     CrossRef
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    Hepatology Research.2026; 56(4): 446.     CrossRef
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    Gastro Hep Advances.2026; 5(2): 100838.     CrossRef
  • Effectiveness and safety of saroglitazar in managing dyslipidaemia and liver enzymes in patients with type 2 diabetes, MASLD, and Stage 3 chronic kidney disease: A 12‐month observational study
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    Diabetes, Obesity and Metabolism.2026; 28(3): 2449.     CrossRef
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    Anesthesiology.2026; 144(2): 365.     CrossRef
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    Peptides.2026; 195: 171462.     CrossRef
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    Journal of Ultrasound in Medicine.2026; 45(6): 1209.     CrossRef
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    Cell.2026; 189(2): 435.     CrossRef
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    Liver International.2026;[Epub]     CrossRef
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    Semiu O. Gbadamosi, David Shi, Abdalla Aly, Caichen K. Zhong, Husam Albarmawi, Aidan McGovern, Anthony Hoovler, Carlos Campos
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    Ho Soo Chun, Minjong Lee
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    Karina Gonzalez-Aldaco, Luis A. Torres-Reyes, Arturo Panduro, Sonia Roman
    International Journal of Molecular Sciences.2026; 27(1): 473.     CrossRef
  • Liver Stiffness Rises Early in MASLD and Drives Inflammation, Lipid Dysmetabolism, and Fibrosis via Piezo1–YAP Mechanotransduction
    Juan Ma, Ning Xie, Ziwei Wang, Xiru Liang, Yulong Han, Qiang Zhao, Ming Wang, Hongwei Lu, Wanyi Kou, William Alazawi, Jinhai Wang, Lu Li, Ning Liu, Na Liu, Haitao Shi, Feng Xu
    Advanced Science.2026;[Epub]     CrossRef
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    Pamela Kakimoto, Natalie Krahmer
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    Seohyun Choi, Jaemin Jeong
    International Journal of Molecular Sciences.2026; 27(2): 619.     CrossRef
  • The burden and mortality impact of cardiovascular disease–metabolic dysfunction–associated steatotic liver disease comorbidity
    Siyuan Tan, Ting Huang, Zixi Zhang, Jiabao Zhou, Hao Chen, Tao Tu, Qiuzhen Lin, Yichao Xiao, Qiming Liu
    Diabetes Research and Clinical Practice.2026; 232: 113092.     CrossRef
  • Non-alcoholic fatty liver disease in Northeast India: a narrative review of rising metabolic syndrome
    Shiludi Longkumer, Maitrayee Dutta Swargiary
    Egyptian Liver Journal.2026;[Epub]     CrossRef
  • Dose‒response relationship between exercise and hepatic steatosis: A systematic review with Bayesian network meta-analysis of randomized controlled trials
    Xinyun Tan, Huihui Zou, Manjie Guo, Jiayu Liu, Xinjuan Huang, Ruoling Yu, Xuelian Liu, Chunxiang Qin
    Journal of Sport and Health Science.2026; 15: 101125.     CrossRef
  • Kefiran, a polysaccharide from kefir grain, modulates gut microbiota and hepatic metabolism to mitigate metabolic dysfunction-associated steatotic liver disease
    Yuanyuan Cui, Jiajia Zhu, Jun Xi, Changhe Ding, Jun Meng
    International Journal of Biological Macromolecules.2026; 341: 150147.     CrossRef
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    Jiamei Song, Dan Liu, Jitong Li, Haoru Cong, Ruixue Deng, Yihan Lu, Jiayi Sun, Jingzhou Zhang
    Journal of Medical Internet Research.2026; 28: e78310.     CrossRef
  • Multi-Omics Evidence Linking Depression to MASLD Risk via Inflammatory Immune Signaling
    Keye Lin, Yiwei Liu, Xitong Liang, Yiming Zhang, Zijie Luo, Fei Chen, Runhua Zhang, Peiyu Ma, Xiang Chen
    Biomedicines.2026; 14(1): 174.     CrossRef
  • Semaglutide-Induced Weight Loss Is the Main Determinant for the Improvement of Hepatic Biochemistry and Elastographic Repeated Measurements with FibroScan® in Patients with Type 2 Diabetes Mellitus and Metabolic Dysfunction-Associated Steatotic Liver Dise
    Savvoula Savvidou, Elektra Augousti-Varela, Aikaterini Damianakou, Miltiadis Chalkias, Ioannis Stergiou
    Metabolic Syndrome and Related Disorders.2026; 24(3): 121.     CrossRef
  • Oxidative stress in metabolic dysfunction-associated steatohepatitis: Mechanisms and emerging therapeutic strategies
    Yidan Chen, Hui Yu, Xinyu Kai, Runting Yin, Zhen Ouyang, Yuan Wei, Cai Zhang
    Biochemical Pharmacology.2026; 246: 117702.     CrossRef
  • Diet intervention altered DNA methylation of potassium voltage-gated channel subfamily Q member 1 in metabolic dysfunction-associated steatohepatitis
    Xinyu Shi, Hualing Song, Xinying Xiong, Shuang Wei, Lei Zhang, Shengfu You, Wenjun Zhou, Guang Ji, Baocheng Liu, Na Wu
    Clinical Epigenetics.2026;[Epub]     CrossRef
  • Mechanisms of scramblases in regulating hepatic lipoprotein secretion and autophagy
    Allen Chen, Chen Zhang, Wen-Xing Ding, Hong-Min Ni
    Journal of Lipid Research.2026; 67(2): 100979.     CrossRef
  • Artificial Intelligence for Fibrosis Diagnosis in Metabolic-Dysfunction-Associated Steatotic Liver Disease: A Systematic Review
    Neilson Silveira de Souza, Théo Cordeiro Veiga Vitório, Raphael Augusto de Souza, Marcos Antônio Dórea Machado, Helma Pinchemel Cotrim
    Diagnostics.2026; 16(2): 261.     CrossRef
  • Tirzepatide versus SGLT2 inhibitors for MASLD: a multi-institutional propensity score-matched cohort study
    Jheng-Yan Wu, Yu-Min Lin, Wan-Hsuan Hsu, Ting-Hui Liu, Ya-Wen Tsai, Po-Yu Huang, Min-Hsiang Chuang, Tsung Yu, Chih-Cheng Lai
    Hepatology International.2026; 20(2): 292.     CrossRef
  • Diagnostic Utility of Serum Activating Transcription Factor 4 and Toll-like Receptor 4 as Early Biomarkers of Inflammation in Metabolic Dysfunction–Associated Steatotic Liver Disease
    Isa Yalcinkaya, Iskender Ekinci, Seyma Dumur, Eda Nur Duran, Hafize Uzun, Melda Yalcinkaya, Elif Kadioglu Yeniyurt, Omer Vehbi Alpaydin, Gulden Anataca, Omur Tabak
    Journal of Clinical Medicine.2026; 15(2): 559.     CrossRef
  • Use of Artificial Intelligence-Assisted Histopathology for Evaluation of Sex-Specific Progression and Regression of Hepatocellular Carcinoma Related to Metabolic Dysfunction-Associated Fatty Liver Disease
    Ke Yin, Yuyun Song, Ran Fei, Xu Cong, Baiyi Liu, Zilong Wang, Xin Ai, Minjun Liao, Yayun Ren, Kutbuddin Akbary, Wei Wang, Qiang Yang, Xiao Teng, Nan Wu, Huiying Rao, Xiaoxiao Wang, Feng Liu
    Diagnostics.2026; 16(2): 234.     CrossRef
  • Effect of SGLT-2 inhibitors on liver fibrosis progression in patients with MASLD: an updated meta-analysis based on RCTs
    Lei Yang, Jiale Ruan, Yingying Fang, Anyi Xu
    Frontiers in Medicine.2026;[Epub]     CrossRef
  • Immune Determinants of MASLD Progression: From Immunometabolic Reprogramming to Fibrotic Transformation
    Senping Xu, Zhaoshan Zhang, Zhongquan Zhou, Jiawei Guo
    Biology.2026; 15(2): 148.     CrossRef
  • Phosphatidylserine Supplementation Improves Metabolic Liver Disease and Glycemic Control in the Presence of Suppressed Oxidative Glucose Metabolism
    Li Dong, Sihan Lin, John Slavin, Satya Gunnam, Zhili Cheng, Shuai Nie, Michael G. Leeming, Nicholas A. Williamson, Magdalene K. Montgomery
    Diabetes.2026; 75(2): 273.     CrossRef
  • Integrating multi-omics and machine learning systematically deciphers cellular heterogeneity and fibrotic regulatory networks in the progression from MASLD to MASH
    Weiheng Wen, Zenghui Liu, Wenliang Tan, Yingzheng Tan, Wei Li, Jian Wan, Hongsai Hu, Zhengwu Jiang, Xing Tang, Jing Yang, Jiao Xiao, Xiongjin Tan, Xun Chen, Peili Wu, Yukun Li
    npj Digital Medicine.2026;[Epub]     CrossRef
  • Morphological characterization of a novel model of steatohepatitis in the FAH -/- pig
    Silvana N. Wilken, Philipp Felgendreff, Anna Minshew, Boyukkhanim Ahmadzada, Seyed M. Hosseiniasl, Sara Kazeminia, Kachi Ezenekwe, Ameya Patil, Byoung U. Park, Ahmer Sultan, Lindsey Smith, Julio Cisneros Correa, Kamal Hussein, Harmeet Malhi, Roger K. More
    Veterinary Pathology.2026; 63(4): 746.     CrossRef
  • Association of cholesterol, high-density lipoprotein and glucose (CHG) index with mortality risk in metabolic dysfunction-associated steatotic liver disease (MASLD) adults: results from two prospective cohorts
    Huangxin Zhu, Lihua Liu, Sicheng Yang, Yunfeng Fu, Yating Pan, Qingan Fu, Fan Du, Xiaodong Zhou
    Cardiovascular Diabetology.2026;[Epub]     CrossRef
  • Stemness CD24 activation promotes hepatocellular carcinoma progression via an immune escape mechanism
    Yin Cai, Lu-Yin Liu, Xiao-Xiao Xia, Hao Tang, Min Xu, Wen-Li Sai, Deng-Fu Yao, Min Yao
    World Journal of Gastroenterology.2026;[Epub]     CrossRef
  • Targeting the 4-HNE–H₂S pathway as a therapeutic strategy for placental injury in pregnancy with MAFLD
    Tianxiao Hu, Jiayu Qi, Yinuo Xu, Jia He, Qingying Tan, Jie Hao, Jing Wang, Jiewei Hong, Jianwei Wang, Lin Chen, Xiaobing Dou
    International Immunopharmacology.2026; 172: 116245.     CrossRef
  • Association of the Triglyceride-Glucose Index With Established Cardiovascular Disease in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease: A Cross-Sectional Study
    Soumayan Mondal, Sidharth S Pattnaik, Nihar Ranjan Mohanty, Sailendra Nayak, Ambika Mohanty, Shubhransu Patro
    Cureus.2026;[Epub]     CrossRef
  • Dysregulation of the AMPK-SREBP1-FASN axis in MASLD: driving a vicious cycle of lipotoxicity and metabolic-immune crosstalk
    Qiqi Zhao, Shengwen Lu, Yu Guan, Zhiwen Sun, Shi Qiu, Aihua Zhang
    Lipids in Health and Disease.2026;[Epub]     CrossRef
  • Prognostic value of non-invasive fibrosis assessment scores in predicting mortality among individuals with metabolic dysfunction-associated steatotic liver disease
    Lingjie Wu, Shunling Cai, Zhongbin Lin, Ruilie Chen, Yuanfeng Zhang, Xiaobing Gong
    BMC Public Health.2026;[Epub]     CrossRef
  • Dapagliflozin‐Associated Reduction in Liver Fat Is Independent of Weight Loss in Patients With Type 2 Diabetes
    Anna V. Naumova, Guilherme Moura Cunha, Nicole J. Kim, Jie Lu, Daniel Isquith, Baocheng Chu, Charles Maynard, Arash Mahdavi, Negar Firoozeh, Karen Ordovas, Xue‐Qiao Zhao, Francis Kim
    Obesity.2026; 34(3): 622.     CrossRef
  • Association Between Metabolically Associated Steatotic Liver Disease (MASLD) and Cardiovascular Risk Scores in Urban Adults
    FARIS HUSSAIN, KELVIN KANAYO NWABUEZE, FATIMA IJAZ, SONIA OUTALEB, MAHMUDUL HASAN NAHID, SYED ABID, MARIAM SALEEM, KHANT NYI ZAYA, SAIFULLAH SYED, HUMAIRA JANANTH, MANAHIL ZARIEF
    Juntendo Medical Journal.2026; 72(1): 54.     CrossRef
  • Metabolic dysfunction-associated steatotic liver disease in patients with type 2 diabetes mellitus in Tanzania: prevalence and predictors
    Evangelista Malindisa, Illuminata Kafumu, Allen Rweyendera, Elisha Mkemangwa, David Majinge, Igembe Nkandala, Paulina Manyiri, Semvua Kilonzo
    BMC Endocrine Disorders.2026;[Epub]     CrossRef
  • Body mass index and metabolic dysfunction associated steatotic liver disease remission among Chinese adults in a retrospective cohort study
    Jiwen Zhang, Yuyin Guo, Bi’e Li, Jiaqian Zhu, Chuang Gao, Qiongdan Zhang, Yong Han, Chuxuan Gu
    Scientific Reports.2026;[Epub]     CrossRef
  • 12,13-diHOME ameliorates MASLD by regulating Sestrin2-mediated AMPK/ULK1/Lipophagy in obese mice
    Kexin Zhang, Chengxia Kan, Hongyan Qiu, Junfeng Shi, Jian Chen, Tianpeng Zheng, Jingwen Zhang, Yujie Ma, Sufang Sheng, Ningning Hou, Fang Han, Xiaodong Sun
    Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease.2026; 1872(4): 168186.     CrossRef
  • Burden of MASLD and liver fibrosis: evidence from Phenome India cohort
    Meghana Arvind, Anshul Verma, Sreeshma Raj K, Satyartha Prakash, Vignesh S. Kumar, Mohammad Azhar Uddin, Ayushi Narayan, Mamta Rathore, Nancy Rawat, Ankita Sahu, Yogesh Kumar, Pulkit Hasmukhbhai Leuva, Monika Sharma, Rajesh S, Dwaipayan Saha, Ankita Mridh
    The Lancet Regional Health - Southeast Asia.2026; 45: 100723.     CrossRef
  • Understanding liver and digestive diseases: a paved road to improve diagnosis, management, and treatment
    Ina Bergheim, Jean Francois Cadranel, Jianguo Chen, Wenxing Ding, Robert Eferl, Carmen Garcia-Ruiz, Hartmut Jaeschke, Firouzeh Kazerouni, Amedeo Lonardo, Derek A. Mann, Nahum Méndez-Sánchez, Camelia Mokhtari, Han Moshage, Chiara Raggi, Pavel Strnad, Oren
    Exploration of Digestive Diseases.2026;[Epub]     CrossRef
  • Prevalence and risk factors for metabolic dysfunction–associated steatotic liver disease in Sweden: Insights from the SCAPIS cohort
    Oumarou Nabi, Jonas Spaak, Göran Bergström, Gunnar Engström, Carl Johan Östgren, Andrei Malinovschi, Joel Kullberg, Anders Blomberg, Tomas Jernberg, Daniel P. Andersson, Hannes Hagström
    Journal of Internal Medicine.2026; 299(4): 481.     CrossRef
  • Interactions Between the Gut Microbiome and Genetic and Clinical Risk Factors for Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) in Patients with Type 2 Diabetes Mellitus from Different Geographical Regions of Argentina
    Bárbara Suarez, Adriana Mabel Álvarez, María Florencia Mascardi, Ana Laura Manzano Ramos, Dong Hoon Woo, María Mercedes Gutiérrez, Guillermo Alzueta, María del Carmen Basbus, Santiago Bruzone, Patricia Cuart, Guillermo Dieuzeide, Teresita García, Olga Esc
    Life.2026; 16(2): 283.     CrossRef
  • Can ammonia scavenging treat MASLD? Evaluating the evidence for L‐ornithine L‐aspartate—A systematic review
    Abdulrahman Ismaiel, Vera Ciornolutchii, Stefan‐Lucian Popa, Dan L. Dumitrascu
    European Journal of Clinical Investigation.2026;[Epub]     CrossRef
  • Predictive factors of metabolic dysfunction associated steatotic liver disease (MASLD) among individuals with cardio-metabolic risk factors, multicenter cross-sectional study, North East Ethiopia
    Getachew Bizuneh Aydagnuhm, Aklile Semu Tefera, Gebru Tesfaw Getahun, Ermiyas Endewunet Melaku
    BMC Gastroenterology.2026;[Epub]     CrossRef
  • Temporal trends and racial/ethnic disparities in hepatocellular carcinoma incidence in the US between 2000-2022
    Wenzhan Jing, Hang Pham, Samuel So
    JHEP Reports.2026; 8(4): 101754.     CrossRef
  • Pirfenidone as a Pleiotropic Antifibrotic Agent in Metabolic Steatohepatitis: From Mechanisms to Clinical Evidence
    Mariana M. Ramírez-Mejía, Guadalupe Ponciano-Rodríguez, Jorge L. Poo, Nahum Méndez-Sánchez
    Archives of Medical Research.2026; 57(4): 103387.     CrossRef
  • Long-term dementia risk in metabolic dysfunction-associated steatotic liver disease: a population-based study
    Andreas Bartholdy, Kristine Frøsig Moseholm, Pernille Yde Nielsen, Nicolai J. Wewer Albrechtsen, Lise Lotte Gluud, Majken Karoline Jensen
    Metabolic Brain Disease.2026;[Epub]     CrossRef
  • Outils diagnostiques de la fibrose hépatique dans la stéatohépatite dysmétabolique
    Candice Gea, Guillaume Feugray, Valéry Brunel
    Revue Francophone des Laboratoires.2026; 2026(579): 36.     CrossRef
  • Mitochondrial dysfunction in MASH: Focusing on chronic inflammation and intercellular communication
    Wanyi Luo, Muxin Yu, Chuwei Zheng, Xiaowen Li, Xiaotian Ma, Guocheng Zeng, Jinming Zhang, Xia Ji, Liyan Sun
    Biochemical and Biophysical Research Communications.2026; 804: 153356.     CrossRef
  • Noninvasive Testing for Metabolic Dysfunction-Associated Steatohepatitis (MASH) and Fibrosis
    Markos Kalligeros, Laurent Castera, Emmanuel A. Tsochatzis, Naim Alkhouri
    Clinics in Liver Disease.2026; 30(2): 323.     CrossRef
  • La ballonisation hépatocytaire : une nouvelle cible thérapeutique dans la Physiopathologie de la MASH
    Arthur Cens, Bart Staels, Réjane Paumelle
    Revue Francophone des Laboratoires.2026; 2026(579): 28.     CrossRef
  • Febuxostat Improves MASLD in Male Rats: Roles of XOR Inhibition and Associated JNK/NRF2/HO-1 Pathway Changes
    Zhiyu Pu, Yangyang Cen, Bowen Yang, Kaijun Xing, Linxi Lian, Xi Chi, Jianjun Yang, Yannan Zhang
    International Journal of Molecular Sciences.2026; 27(2): 1069.     CrossRef
  • Association between blood heavy metal levels and subtypes of steatotic liver disease: A nationally representative cross-sectional analysis in South Korea
    Ji Hye Choi, Juyeong Kim, Yesol Yim, Hyunjee Kim, Jiyoung Hwang, Ho Geol Woo, Sang Youl Rhee, Yerin Hwang, Dong Keon Yon
    Medicine.2026; 105(4): e47365.     CrossRef
  • Biological aging across the metabolic dysfunction–associated steatotic liver disease spectrum: A systematic review
    Chukwuemeka E. Ogbu, Stella C. Ogbu, Chidera P. Ogbu, Chinazor Umerah
    iLIVER.2026; 5(1): 100222.     CrossRef
  • Fermented Foods and the Gut–Liver Axis: Modulation of MASLD Through Gut Microbiota
    Agnieszka Wesołek-Leszczyńska, Dawid Rosiejka, Kalina Bogdańska, Paweł Bogdański
    Nutrients.2026; 18(3): 542.     CrossRef
  • Association of four insulin resistance indices with liver‐related adverse outcomes: A prospective cohort study
    Xiao‐Meng Wang, Hao Yan, Wen‐Fang Zhong, Jia‐Hao Xie, Huan Chen, Jun‐Jie Wang, Wei‐Qi Song, Dong Shen, Pei‐Dong Zhang, Xi‐Ru Zhang, Jiao‐Jiao Ren, Dan Liu, Zhi‐Hao Li, Chen Mao
    Diabetes, Obesity and Metabolism.2026; 28(5): 3598.     CrossRef
  • Efficacy of empagliflozin in patients with metabolic dysfunction-associated steatotic liver disease with or without diabetes: a systematic review and meta-analysis of randomized controlled trials
    Khalid I. AlHussaini
    Frontiers in Medicine.2026;[Epub]     CrossRef
  • Association of Metabolic Dysfunction-Associated Steatotic Liver Disease with Extrahepatic Cancers and Sarcopenia
    Yusuf Yilmaz, Alina M. Allen, Jérôme Boursier, Juan P. Arab
    Clinics in Liver Disease.2026; 30(2): 289.     CrossRef
  • Associations of relative fat mass with metabolic dysfunction–associated steatotic liver disease and liver fibrosis: evidence from the U.S. NHANES 2017–2023
    Hai-Yuan Zhong, Ling-Dan Ma, Jin-Cheng Li, Dan Jiang, Yu-Mei Qin, Ming-Yu Lai, Guang Xiong
    BMC Gastroenterology.2026;[Epub]     CrossRef
  • Gut microbiota, liver disease, and perioperative anesthesia: interactions, risks, and therapeutic opportunities
    Lei Shi, Ye Yu, Zihan Ma, Weiyi Jiang
    Frontiers in Cellular and Infection Microbiology.2026;[Epub]     CrossRef
  • Lessons learned from viral hepatitis testing that inform law and policy responses to steatotic liver disease
    Jeffrey V. Lazarus, Christopher J. Kopka, Aina Nicolàs, Safura Abdool Karim, Meena B. Bansal, Michael Betel, John F. Dillon, Pere Gines, Aleksander Krag, Veronica Miller, Cynthia A. Moylan, Alisa Pedrana, Paula Petrone, Jörn M. Schattenberg, Sunil S. Solo
    Nature Reviews Gastroenterology & Hepatology.2026; 23(4): 355.     CrossRef
  • SIRT3 ameliorates hepatic inflammation, oxidative stress, and fibrosis in HFD- or MCD diet-fed mice
    Huifang Lv, Wenyue Sun, Cuixia Tian, Chunyong Bian, Zhongting Lu, Xin Guo
    The Journal of Nutritional Biochemistry.2026; 152: 110276.     CrossRef
  • Paulobutalipin, a Lipid Accumulation Inhibitor from a Streptomyces sp.
    Thanh-Hau Huynh, Hoseo Lee, Sangwook Kang, Jeong-Hyeon Kim, Huiyeong Ju, Ki-Bong Oh, Sang-Jip Nam, Ja Hyun Koo, Dong-Chan Oh
    Journal of Natural Products.2026; 89(2): 682.     CrossRef
  • MASLD, MASH, and the CKM Spectrum
    Faiez Zannad, Muhammad Shahzeb Khan, Nisha Bansal, Michael Böhm, Sven M. Francque, Nicolas Girerd, James L. Januzzi, Veronica Miller, Marie-Eve Piché, Vlad Ratziu, Bart Staels, Harriette G.C. Van Spall, Arun J. Sanyal, Javed Butler
    JACC.2026; 87(15): 2006.     CrossRef
  • Polyunsaturated fatty acids as a potential preventive and therapeutic intervention for metabolic dysfunction–associated steatotic liver disease and its progression to hepatocellular carcinoma
    Thomai Kouti, Panayiota Christodoulou, Stephanos Christodoulides, Foula Protopapa, Charalambos Michaeloudes, Paraskevi A. Farazi
    Frontiers in Nutrition.2026;[Epub]     CrossRef
  • Providing holistic care for patients with metabolic dysfunction‐associated steatotic liver disease/metabolic dysfunction‐associated steatohepatitis: Key aspects of clinical assessment and how to develop individualised care plans for surveillance and inter
    Lanlan Chen, Paul Horn, Frank Tacke
    Diabetes, Obesity and Metabolism.2026; 28(S2): 46.     CrossRef
  • MASH in Type 2 Diabetes: Pathophysiology, Diagnosis, and Therapeutic Management—A Narrative Review
    Adela Gabriela Ştefan, Adina Mitrea, Diana Clenciu, Ionela Mihaela Vladu, Maria Magdalena Roşu, Diana Cristina Protasiewicz-Timofticiuc, Theodora Claudia Radu-Gheonea, Ion-Cristian Efrem, Anca Maria Amzolini, Beatrice Elena Vladu, Ana-Maria Efrem, Delia-V
    Medicina.2026; 62(2): 325.     CrossRef
  • The active components of the Danshen-Shanzha herb-pair exert a protective effect on MASLD by synergistically promoting fatty acid oxidation via the activation of PPARα, Plin-5 and Plin-2
    Ying Yang, Yaxing Li, Zirong Zhou, Hui Li, Yihan Ma, Wenjie Bi, Mengjiao Li, Xiaoli Liu, Qiang Jia, Liwen Han, Songsong Wang
    Journal of Ethnopharmacology.2026; 362: 121374.     CrossRef
  • Efficacy and Safety of Statins in MASLD and Other Chronic Liver Diseases
    I. Commins, D. Clayton-Chubb, N. Janko, A. Majeed, W. Kemp, S. K. Roberts
    Medical Sciences.2026; 14(1): 84.     CrossRef
  • Detection of hepatic steatosis with ultrasound-guided attenuation parameter (UGAP) in metabolic dysfunction-associated steatotic liver disease (MASLD) compared with proton density fat fraction (PDFF): Impact of measurement number and region of interest (R
    Marie Byenfeldt, Christer Grönlund, Patrik Nasr, Anna Lindam, Mattias Ekstedt, Peter Lundberg, Johan Kihlberg
    Ultrasound.2026;[Epub]     CrossRef
  • Artificial intelligence and digital transformation of gastroenterology and hepatology: A critical review of clinical applications and future challenges
    Miguel Suarez, Raquel Martínez, Félix González-Martínez, Ana María Torres, Jorge Mateo
    World Journal of Hepatology.2026;[Epub]     CrossRef
  • Efficacy of ursodeoxycholic acid in metabolic dysfunction-associated steatotic liver disease: an umbrella review of meta-analyses on liver enzymes
    Alsu R. Khurmatullina, Dmitrii N. Andreev, Igor V. Maev, Andrey V. Zaborovsky, Yury A. Kucheryavyy, Petr A. Beliy, Philipp S. Sokolov
    Frontiers in Medicine.2026;[Epub]     CrossRef
  • Panax notoginseng Saponins Ameliorate High‐Fat Diet‐Induced Liver Injury via Mechanisms Involving TLR4‐Mediated Signaling and Lipid Metabolism
    Rong Li, Junyu Ma, Mengyao Li, Bangzhao Zeng, Xuexun Li, Xiaoyan Bi, Xin Zhao, Qin Gao, Yanling Yao, Yang Jiang, Chunmei Zhang, Fuli Ya
    Food Science & Nutrition.2026;[Epub]     CrossRef
  • MicroRNA-146a Protects against Hepatocellular Carcinoma through Suppression of CCL5
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    Cancer Research Communications.2026; 6(2): 359.     CrossRef
  • Imaging in MASLD
    Sudhakar K. Venkatesh
    Expert Review of Gastroenterology & Hepatology.2026; 20(3): 257.     CrossRef
  • Beyond Taste: The Impact of Chocolate on Cardiovascular and Steatotic Liver Disease Risk Factors
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    Nutrients.2026; 18(4): 636.     CrossRef
  • Occurrence and prognosis of metabolic dysfunction-associated steatosis liver disease and gastrointestinal tumors: a systematic review and meta-analysis
    Siyu Duan, Yiyi Wei, Zhuoyu Ding, Chaomin Pan, Li Yang, Yan Gu, Xinke Wang
    PeerJ.2026; 14: e20616.     CrossRef
  • Liver involvement in dengue virus infection: a narrative review
    Madunil Anuk Niriella, Ravini Amila Premaratna, Shashini Hathurusinghe, Ranjan Premaratna, Anuradha Supun Dassanayake, Hithanadura Janaka de Silva
    Journal of Clinical Virology Plus.2026; 6(2): 100247.     CrossRef
  • Toll Like Receptor 4: A Potential Link Between Obesity and Metabolic Diseases
    Ghadeer Alhamar, Joanna Razafiarison, Fawaz Alzaid, Fahd Al‐Mulla, Rasheed Ahmad
    Obesity Reviews.2026;[Epub]     CrossRef
  • Editorial: Pharmacological and nutritional approaches to metabolic associated fatty liver disease: a step towards achieving SDG 3
    Mahmut Bodur, Bojana Vidović, Anastasios Nikolaou, Birsen Yilmaz
    Frontiers in Pharmacology.2026;[Epub]     CrossRef
  • Impact of newer antihyperglycemic agents on hepatic complications: A systematic review and meta-analysis of data from 5.3 million patients with type 2 diabetes mellitus
    Jiwon Yang, Yeongseok Hwang, Jin-Sung Ju, Seungbong Han, Jihyun An, Ju Hyun Shim
    Hepatology.2026;[Epub]     CrossRef
  • A novel C/EBPα–miR-335-5p–PRKAA2 regulatory axis drives hepatic lipid accumulation in MASLD
    Xiying Zeng, Yajing Xu, Sufang You, Honghong Duan, Qingyan Cai, Huibin Huang
    Scientific Reports.2026;[Epub]     CrossRef
  • Altered Tryptophan–Kynurenine Pathway and Low-Grade Inflammation in Metabolic Dysfunction–Associated Steatotic Liver Disease (MASLD): Insights from LC–MS/MS–Based Metabolite Profiling
    Kübranur Ünal, Leyla İbrahimkhanlı, Mehmet Emre Erol, Nemat İbrahimkhanlı, Sabri Engin Altıntop, Mahi Nur Cerit, Ethem Turgay Cerit, Halit Nahit Şendur
    International Journal of Tryptophan Research.2026;[Epub]     CrossRef
  • Modulation of metabolic, inflammatory, fibrotic, and cell death pathways by resmetirom in metabolic dysfunction-associated steatohepatitis (MASH): a transcriptomic profiling study
    Chen-yang He, Zhi-hua Wang, Jian-ping Weng, Hans Strijdom, Suo-wen Xu
    Acta Pharmacologica Sinica.2026; 47(4): 1070.     CrossRef
  • From HBV to MASLD Cirrhosis: Mechanistic Insights and Therapeutic Strategies
    Hanqi Yu, Hongfan Ding, Yang Huang, Haoze Cao, Yuan Ding, Weilin Wang
    Portal Hypertension & Cirrhosis.2026; 5(2): 170.     CrossRef
  • Inflammation burden index as a complementary marker for the assessment of hepatic steatosis and fibrosis: evidence from NHANES 2017–2018
    Shaoguang Chen, Lixiao Zhu, Yulou Jiang
    Abdominal Radiology.2026;[Epub]     CrossRef
  • Deubiquitinase USP2 promotes hepatic stellate cell activation via p300 stabilization
    Seunghee Byun, Hyunsik Kim, Sun‐Ho Lee, Jae‐Hwan Kwon, Hyunseung Kim, Jung‐Yoon Yoo, Soo‐Yeon Park, Ho‐Geun Yoon
    FEBS Letters.2026; 600(9): 1318.     CrossRef
  • Epidemiological Trajectories and Quality of Care Disparities of MASLD in Asia, 1990–2023
    Kexin Zhang, Wei Xu, Chengxia Kan, Sufang Sheng, Fang Han, Jian Chen, Xuan Li, Ningning Hou, Xiaodong Sun, Ying Xue
    Digestive Diseases and Sciences.2026;[Epub]     CrossRef
  • Impact of different subtypes of steatotic liver disease on immune checkpoint inhibitor-related drug-induced liver injury: a retrospective study
    Tianyi Ma, Zhanfang Guo, Haijia Bi, Huawei Yuan, Yu Li, Mei Sun
    European Journal of Gastroenterology & Hepatology.2026; 38(3): 351.     CrossRef
  • Triglyceride glucose index—a body shape index (TyG-ABSI) outperforms traditional obesity indices in predicting all-cause and cardiovascular mortality in metabolic-dysfunction associated steatotic liver disease: the mediating role of biological aging
    Guodong Yang, Wenli He, Xin Qiu, Shuang Shen, Peishu Li, Yifei Feng, Jiayuan Zhang, Bangde Xiang
    Cardiovascular Diabetology.2026;[Epub]     CrossRef
  • The relationship between acromegaly and hepatic steatosis: insights from FibroScan imaging
    Tugce Apaydin, Haluk Tarik Kani, Caglayan Keklikkiran, Yusuf Yilmaz, Dilek Gogas Yavuz
    Journal of Endocrinological Investigation.2026; 49(5): 1029.     CrossRef
  • From Childhood to Old Age: Current Knowledge and Practical Approaches to Metabolic Dysfunction-Associated Steatotic Liver Disease
    Iwona Gorczyca-Głowacka, Michał Tarnowski, Anna Zmelonek-Znamirowska, Przemysław Wolak
    Journal of Clinical Medicine.2026; 15(4): 1536.     CrossRef
  • Development of a Lipidomics-Based Cell Screening Platform for Indirect Antioxidants Targeting Oxidized Lipid Droplet Formation and Mitochondrial Membrane Abnormality
    Yuzu Shibata, Toshihiro Sakurai, Akiko Sakurai, Misuzu Sato, Shu-Ping Hui
    Nutrients.2026; 18(5): 719.     CrossRef
  • Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD): A Multisystemic Narrative Review of Cardiovascular and Oncological Implications
    Menatalla M. A. Mohamed, Maha M. M. I. Taha, Mohnd M. M. R. Ibrahim
    ASIDE Gastroenterology.2026; 2(2): 15.     CrossRef
  • Effects of pemafibrate on liver fibrosis in patients with MASLD and hypertriglyceridemia: A 2-year retrospective observational study using MR elastography
    Hidenao Noritake, Takafumi Inoue, Takashi Yonekura, Hiroki Tamakoshi, Yuya Ida, Moe Matsumoto, Tomohiko Hanaoka, Maho Yamashita, Masahiro Umemura, Kazuyoshi Ohta, Takeshi Chida, Kazuhito Kawata
    Journal of Clinical Lipidology.2026; 20(5): 947.     CrossRef
  • Fecal microbiota transplantation alleviates steatosis and inflammation in high-fat and high-sugar diet-induced fatty liver in mice
    Fangxia Mi, Jinglu Guo, Wentao Zheng, Jianwei Shen, Hua Ye
    Frontiers in Cell and Developmental Biology.2026;[Epub]     CrossRef
  • Coagulation protease-activated receptor-2 (PAR2) promotes dyslipidemia, obesity and MASLD through repression of the hepatic pioneer factor HNF4α
    Xinru Chen, Nga Nguyen, Susan E. Turner, Albert K. Tai, Manal F. Abdelmalek, Lidija Covic, Athan Kuliopulos
    JHEP Reports.2026; 8(6): 101796.     CrossRef
  • Real-world comparison of GLP-1 agonists versus physical activity in metabolic dysfunction-associated steatotic liver disease
    Jason N. Chen, Bulent Tolga Delibasi, James Wang, Thomas Tran, Connie Hu, Charles W. Randall
    BMC Gastroenterology.2026;[Epub]     CrossRef
  • Rab5 nucleotide binding promotes oxidative metabolism to fuel hepatocellular carcinoma cell proliferation
    Kelly O. Otakhor, Mohd Ali Abbas Zaidi, Rebecca E. Oberley-Deegan, Moorthy P. Ponnusamy, Kurt W. Fisher, Micah B. Schott
    Journal of Biological Chemistry.2026; 302(4): 111321.     CrossRef
  • Using an integrative multi-omics and in vitro approach to investigate the role of tris(2-butoxyethyl) phosphate in promoting hepatic steatosis
    Gang Zhou, Xihan Gu, Xinyao Zhou, Shuai Chen, Hanyang Liu, Jing Wang
    BMJ Open Gastroenterology.2026; 13(1): e002123.     CrossRef
  • Epigenetic regulation in MASLD – insight for therapeutic target discovery
    Jan H. Britsemmer, Nuria Lopez Alcantara, Henriette Kirchner
    Epigenomics.2026; 18(3): 311.     CrossRef
  • Astaxanthin alleviates altered hepatic lipid metabolism and oxidative stress in animals fed a high-sucrose diet
    Matias Rodrigo Vargas, María del Rosario Ferreira, Paola Inés Ingaramo, Pablo Collins, María Eugenia D’Alessandro
    Frontiers in Nutrition.2026;[Epub]     CrossRef
  • Metabolic Dysfunction-Associated Steatotic Liver Disease in Africa
    Mohamed El-Kassas, C. Wendy Spearman, Manal El-Sayed, Zobair M. Younossi
    Clinics in Liver Disease.2026; 30(2): 513.     CrossRef
  • Patients’ Experience of Stigma as the Hidden Burden of Metabolic Dysfunction-Associated Steatotic Liver Disease: A Descriptive Qualitative Study with Thematic Analysis
    Johanne Lisa Jensen-LeBlanc, Pernille Andreassen, Mette Munk Lauridsen, Lea Ladegaard Grønkjær
    Healthcare.2026; 14(5): 579.     CrossRef
  • Targeting magnesium homeostasis: a novel therapeutic strategy for liver diseases
    Lili Ji, Hanhan Yu, Ruwen Wang, Hongmei Yan, Xiaofeng Yin, Shanshan Guo, Ru Wang
    Frontiers in Nutrition.2026;[Epub]     CrossRef
  • The Role of Butyrate in People with Metabolic Dysfunction-Associated Steatotic Liver Disease and Related Metabolic Comorbidities: A Systematic Review
    Alicia González-González, Virginia Soria-Utrilla, María Isabel Fontalba-Romero, María Ángeles Núñez-Sánchez, Antonio Adarve-Castro, María Isabel Queipo-Ortuño, Bruno Ramos-Molina, José Ignacio Martínez-Montoro, José Carlos Fernández-García
    Current Obesity Reports.2026;[Epub]     CrossRef
  • Creatinine-to-body weight ratio as an independent predictor of hepatic steatosis severity in metabolic dysfunction-associated steatotic liver disease: a cross-sectional study
    Xiaoning Sun, Xiaozhong Wang, Ayesha Younas, Shuanghu Wang, Muhammad Sohail, Jiaojian Lv, Zuxiu Huang, Yunxiao Liu
    BMC Gastroenterology.2026;[Epub]     CrossRef
  • Metabolic liver imaging: What you need to know
    Luigi Asmundo, Amirkasra Mojtahed, Samay Prakash, Theodore T. Pierce, Jingwei Wei, Angelo Vanzulli
    Digestive and Liver Disease.2026; 58(4): 433.     CrossRef
  • Gut microbiota supportive dietary pattern associated with reduced MASLD risk mediated by metabolomic profiles: a prospective cohort study
    Dong-Run Li, Ke-Ru Li, Ying Wang, Jia-Qi Zheng, Wen-Rui Zheng, Bang-Quan Liu, Jia-Cheng Liu, Rui-Han Bao, Ting-Ting Gong, Qiu-Ju Sheng, Shan-Yan Gao, Qi-Jun Wu
    Nutrition Journal.2026;[Epub]     CrossRef
  • Metabolic Dysfunction-Associated Steatotic Liver Disease in Latin America
    Claudia P. Oliveira, Mario Guimarães Pessoa, Luis Antonio Diaz, Juan Pablo Arab, Adrian Gadano, Marco Arrese
    Clinics in Liver Disease.2026; 30(2): 529.     CrossRef
  • Integrated lifestyle management to mitigate MASLD risk in patients with chronic kidney disease: a prospective cohort study
    Chao Yan, Xinxin Shen, Shaojie Han, Jinzheng He, Tongxu Wang, Xiaobing Gong, Jindong Ding Petersen
    Journal of Translational Medicine.2026;[Epub]     CrossRef
  • Retatrutide in type 2 diabetes mellitus and obesity: an overview
    Theodoros Panou, Evanthia Gouveri, Djordje S. Popovic, Nikolaos Papanas
    Expert Review of Clinical Pharmacology.2026; 19(4): 313.     CrossRef
  • Impact of Documented Social Vulnerability on Clinical Outcomes in Metabolic Dysfunction‐Associated Steatotic Liver Disease
    Pojsakorn Danpanichkul, Yanfang Pang, Maria Inggriani, Supapitch Sirimangklanurak, Matheus Souza, Ahmad Anouti, Andrew F. Ibrahim, Nikki Duong, Thomas G. Cotter, Thomas A. Kerr, Donghee Kim, Mazen Noureddin, Karn Wijarnpreecha
    Liver International.2026;[Epub]     CrossRef
  • Optimal screening criteria for metabolic dysfunction-associated steatotic liver disease with fibrosis
    Byeong Geun Song, Myung Ji Goh, Wonseok Kang, Geum-Youn Gwak, Yong-Han Paik, Moon Seok Choi, Joon Hyeok Lee, Dong Hyun Sinn
    Annals of Hepatology.2026; 31(2): 102199.     CrossRef
  • The role and possible mechanism of intestinal fungi in the progression of chronic liver diseases
    Yirui Hu, Ye Yang, Shuyan Wang, Huikuan Chu
    npj Biofilms and Microbiomes.2026;[Epub]     CrossRef
  • Effect of Hormone Replacement Therapy on Liver and Cardiometabolic Outcomes in Peri‐Menopausal MASLD
    Alex E. Henney, Jo Wilson, David R. Riley, Uazman Alam, Daniel J. Cuthbertson
    Liver International.2026;[Epub]     CrossRef
  • Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) and Risk of Gynecologic Cancer: A Nationwide Cohort Study
    Min Jin Jeong, Yong Seok Lee, Youn Jin Choi, Kyung Do Han
    Cancers.2026; 18(6): 894.     CrossRef
  • Association of Metabolic Dysfunction-Associated Steatohepatitis with Metabolic-Related Diseases
    Leonidas Diamantopoulos, Markos Kalligeros, Scott D. Isaacs, Didac Mauricio
    Clinics in Liver Disease.2026; 30(2): 271.     CrossRef
  • Hospitalization Trends Due to Chronic Liver Diseases: Vicious Circle of Co-Morbidities and Hospitalization Length
    Ivana Pantic, Nikola Grubor, Sofija Lugonja, Nina Rajovic, Svetlana Miltenovic, Marija Brankovic, Tijana Gmizic, Tamara Milovanovic
    Clinics and Practice.2026; 16(3): 57.     CrossRef
  • Integrated multi-omics analysis identifies and validates endoplasmic reticulum stress and mitophagy-related biomarkers in MASLD
    Quanrun Chen, Limin Liu, Jinqiu Feng, Chong Zhang, Zongming Zhang
    Scientific Reports.2026;[Epub]     CrossRef
  • Non-invasive risk stratification of metabolic dysfunction-associated steatotic liver disease and liver fibrosis in adults with type 1 diabetes
    Manuel Ramón García-Sáenz, Marilu Cervantes-Maldonado, Luis Angel López-Cruz, Eduardo Salif Luna-Avila, Paulo César Gete Palacios, Cristina Martínez-Berdeja, Omar Jaime-Leal, Aldo Ferreira-Hermosillo
    Frontiers in Endocrinology.2026;[Epub]     CrossRef
  • MEANDERLINE BASED MICROSTRIP ANTENNA DESIGN FOR LIVER TUMOR DETECTION
    Volkan Akdoğan, Fatih Özkan Alkurt
    Kahramanmaraş Sütçü İmam Üniversitesi Mühendislik Bilimleri Dergisi.2026; 29(1): 401.     CrossRef
  • Metabolic-associated steatotic liver disease in children and adolescents: a scoping review and narrative synthesis of epidemiology, risk factors, and screening approaches with emerging implications for sub-Saharan Africa
    Bruno Basil, Peace Ngozi Okoro
    Frontiers in Endocrinology.2026;[Epub]     CrossRef
  • Metabolic Dysfunction-Associated Steatohepatitis (MASH)-Cirrhosis Clinical Trials: Lessons Learned and Future Directions
    Rashmee Patil, Winston Dunn, Mazen Noureddin, Naim Alkhouri
    Drugs.2026; 86(5): 627.     CrossRef
  • The Gut‐Liver Axis in Metabolic Dysfunction‐Associated Steatotic Liver Disease: From Mechanistic Insights to Precision Therapeutics
    Shaoliang Zhu, Mengjie Zou, Qijun Wu, Yan Zou, Tingting Tan, Zhangnan Huang, Zheng Gong, Honglin Luo, Xiaofeng Dong
    The FASEB Journal.2026;[Epub]     CrossRef
  • Pharmacologic Treatment of Metabolic Dysfunction-Associated Steatotic Liver Disease in the Context of Type 2 Diabetes
    Konstantinos Malandris, Konstantinos Charalampidis, Rohit Loomba, Emmanouil Sinakos
    Current Diabetes Reports.2026;[Epub]     CrossRef
  • Association between weekend catch-up sleep and Metabolic dysfunction-associated steatotic liver disease in US adults
    Jinlong Chen, Wei Wang, Jie He, Xinxin Fang
    Clinical and Experimental Medicine.2026;[Epub]     CrossRef
  • Ginsenoside Rg1 alleviates MASH by targeting GLS2 to enhance PINK1/Parkin-mediated mitophagy and improve mitochondrial function
    Zhijian Wang, Yinuo Wang, Peiyun Peng, Huating Luo, Liuling Xiao, Wenxiang Huang
    Biochemical Pharmacology.2026; 249: 117891.     CrossRef
  • Heterogeneous associations of regional adipose depots with liver fibrosis in U.S. adults
    Kuan-Yu Lai, Chun-Yi Wang, Hsian-Han Kao, Wen-Yuan Lin, Tsung-Po Chen
    Metabolism Open.2026; 30: 100461.     CrossRef
  • MASLD In Children - A Distinct Phenotype?
    Pervej Alom Barbhuiya, Manash Pratim Pathak
    Current Obesity Reports.2026;[Epub]     CrossRef
  • DNA hypermethylation of choline kinases drives blockage of choline-phosphatidylcholine biosynthesis: lipidomic biomarkers and epigenetic insights of hepatic steatosis induced by arsenic
    Qiwen Fu, Qi Wang, Dingyi Song, Xingcheng Zhou, Hualin Chen, Shaofeng Wei, Lu Ma
    BMC Medicine.2026;[Epub]     CrossRef
  • Comments on “Long-term serum ferritin dynamics in patients receiving antiviral treatment for hepatitis C virus infection”
    Preeti Lamba
    Journal of the Formosan Medical Association.2026;[Epub]     CrossRef
  • Association between triglyceride glucose-body mass index and metabolic dysfunction-associated steatotic liver disease in South Korean pregnant women
    Yuqin Shen, Dongqian Yang, Li Zhang, Rong Shuai
    Scientific Reports.2026;[Epub]     CrossRef
  • Combined effect of MASLD and low muscle strength on the risk of osteoporotic fractures: A UK Biobank cohort study
    Yongin Cho, Jong Hyun Jhee, Jong Ho Jhee, Hye-Sun Park
    European Journal of Endocrinology.2026; 194(3): 357.     CrossRef
  • Hepatoprotective Effects of Combined Inulin-Glucomannan Non-Starch Polysaccharide Against Western Diet-Induced Metabolic Dysfunction-Associated Steatotic Liver Disease
    I Gede Putu Adhi Wedharga, Made Cahyani Trisna Ananda, Nadilla Faiza Richadini, Bernadette Dian Novita, Herjunianto Herjunianto, Silvia Sutandhio, Adi Pramono Hendrata, Mulya Dinata, Yu Hirata, Suryo Kuncorojakti, Hendy Wijaya, Dawei Chen, Ester Natalia D
    Journal of Pharmaceutical Innovation.2026;[Epub]     CrossRef
  • Broccoli-Derived Exosome-like Nanoparticles Alleviates Metabolic Dysfunction-Associated Steatotic Liver Disease Through Modulating the Gut–Liver Axis
    Feng Zhang, Ruolan Liu, Tongxiao Xu, Wentao Xu, Kunlun Huang, Xiaoyun He
    Nutrients.2026; 18(6): 953.     CrossRef
  • Therapeutic targets for metabolic dysfunction-associated steatohepatitis: a personalized approach to disease management
    Mary E. Rinella, Silvia Sookoian
    Nature Reviews Gastroenterology & Hepatology.2026; 23(6): 460.     CrossRef
  • Association of Metabolic Dysfunction-Associated Steatotic Liver Disease and Kidney Failure in the CKD Population
    Jin Kyung Kwon, Minsang Kim, Jinsun Lee, Jae-ik Oh, Jung Hun Koh, Min Woo Kang, Jeong Min Cho, Seong Geun Kim, Hyuk Huh, Sehyun Jung, Semin Cho, Soojin Lee, Eunjeong Kang, Yaerim Kim, Dong Ki Kim, Kyungdo Han, Sehoon Park
    Kidney International Reports.2026; 11(5): 106414.     CrossRef
  • Hepatic Outcomes in Lean Versus Nonlean Metabolic Dysfunction–Associated Steatotic Liver Disease: Propensity‐Matched Cohort Study
    Rishi Chowdhary, Manjeet Kumar Goyal, Ashita Rukmini Vuthaluru, Megh Patel, Tanisha Sehgal, Kirti Arora, Rahul Chowdhary, Varun Mehta, Akash Batta, Omesh Goyal
    Hepatology Research.2026; 56(6): 1026.     CrossRef
  • Cytoglobin in Hepatic Stellate Cells Plays Anti-Fibrotic Role in Chronic Liver Injury
    Norifumi Kawada
    Antioxidants.2026; 15(3): 383.     CrossRef
  • Capabilities of magnetic resonance imaging in quantitative assessment hepatic steatosis in patients with different body mass index
    Yu. N. Savchenkov, G. E. Trufanov, V. A. Fokin, E. A. Ionova, T. A. Anosova, A. V. Anisonyan, E. S. Sbikina, O. V. Bodrova
    Medical alphabet.2026; (4): 40.     CrossRef
  • MASLD as a systemic metabolic disease: expanding the scope of cardiovascular-kidney-metabolic (CKM) syndrome
    Xiao-Dong Zhou, Qiong-Yue Fan, Giovanni Targher, Christopher D. Byrne, Qin-Fen Chen, Michael D. Shapiro, Yuxing Dong, Ki-Chul Sung, Gregory Y. H. Lip, Jeffrey V. Lazarus, Ming-Hua Zheng
    Science China Life Sciences.2026; 69(6): 1950.     CrossRef
  • Frailty, cardiovascular health, and the risk of mortality and extrahepatic diseases in patients with metabolic dysfunction-associated steatotic liver disease
    Jie Li, Jiang Li, Xiaoqin Xu, Ningjian Wang, Bin Wang, Yingli Lu
    Maturitas.2026; 208: 108917.     CrossRef
  • Myeloid KIF13B suppresses the STT3A/CTSD/THBS1 axis to prevent MASH
    Kaikai Lu, Xianqin Shen, Ziyang Guo, Jingxuan Chen, Lei He, Aiden Xian, Si Mei, Yufei Han, Yinqi Zhao, Jinxuan Chen, Sijing Shi, Guolin Miao, Yitong Xu, Zihao Zhou, Lianxin Zhang, Chao Zhai, Ziwei Wang, Ling Zhang, Minghua Zheng, Lin Yao, Wei Huang, Yuhui
    Hepatology.2026;[Epub]     CrossRef
  • Association of serum uric acid and serum uric acid/creatinine ratio with metabolic dysfunction-associated fatty liver disease in young adults: a retrospective study
    Yue Li, Zixian Li, Siyu Wu, Ling Cao, Beibei Qian, Junxian Tao, Zhimin Qian, Li Xie, Xiaoli Cai, Xiaofang Sun, Ying Li, Zhenwen Zhang, Caifeng Yan, Dunmin She
    BMC Endocrine Disorders.2026;[Epub]     CrossRef
  • Niacin Derivatives in MASLD: Metabolic and Therapeutic Insights
    Marina Idalia Rojo-López, Julia Niño-Narvión, Maria Antentas, Berta Fernández-Camins, Elizabeth Martínez-Rojo, Maria Poca, María Antonia Martínez-Sánchez, Bruno Ramos-Molina, Joana Rossell, Didac Mauricio, Josep Julve
    Nutrients.2026; 18(6): 996.     CrossRef
  • Metabolic Dysfunction-Associated Steatotic Liver Disease
    James M. Paik, Linda Henry, Khalid AlNaamani, Ariana Nader, Maria Stepanova, Mei-Hsuan Lee, Ming-Lung Yu, Zobair M. Younossi
    Clinics in Liver Disease.2026; 30(2): 241.     CrossRef
  • Assessing the Relationship Between Steatotic Liver Disease and Barrett’s Esophagus: A Cross-Sectional Analysis of 5507 Screening Participants
    Nikolaus Götz, Andreas Völkerer, Hannah Hofer, Sarah Wernly, Franz Singhartinger, Ewald Wöll, Elmar Aigner, Maria Flamm, Christian Datz, Bernhard Wernly
    Zeitschrift für Gastroenterologie.2026; 64(05): 470.     CrossRef
  • Prevotella‐Derived Butyrate Inhibits CD8+ T‐Cell Glycolysis via AKT/mTOR Signalling to Alleviate MASH
    Feixiang Xiong, Fengna Yan, Yuyong Jiang, Xiaomin Ji, Tong Wu, Yang Zhou, Xuejie Zhang, Dandan Chen, Yixin Hou
    Liver International.2026;[Epub]     CrossRef
  • CT-assessed abdominal visceral adiposity and MASLD: a sex-stratified cross-sectional analysis
    Linying Xu, Ting Chen, Yitian Xie, Xueyu Xiang, Yupeng Liu, Chongyong Xu, Shuran Wang
    Frontiers in Nutrition.2026;[Epub]     CrossRef
  • MetALD at the crossroads of metabolic and alcohol-related liver disease
    Gustavo Ayares, Luis Antonio Díaz, Juan Pablo Arab, Marco Arrese
    Trends in Endocrinology & Metabolism.2026;[Epub]     CrossRef
  • Placebo-associated changes in MRI-PDFF and metabolic parameters in MASLD patients from phase Ib/IIa clinical trials: implications for early-phase trial design and translational endpoint interpretation
    Mengdi Lu, Hong Zhang, Xiaoxue Zhu, Jia Xu, Lin Xiang, Yue Hu, Jixuan Sun, Jiajia Mai, Yanhua Ding
    Frontiers in Pharmacology.2026;[Epub]     CrossRef
  • Aging-related skeletal muscle loss on the incidence of chronic kidney disease in patients with metabolic dysfunction-associated steatotic liver disease
    Aryoung Kim, Danbee Kang, Sung Chul Choi, Dong Hyun Sinn, Hye Ryoun Jang, Geum-Youn Gwak
    The Journal of nutrition, health and aging.2026; 30(5): 100827.     CrossRef
  • Multi-omics integration reveals ANXA6-high γδ T cell–endothelial communication as a potential link between periodontitis and MASLD
    Zhongxuan Zhang, Zihan Ma, Ruidong Zhang, Min Ye, Zhongyu Shi, Miao Yu, Lingling Ou
    npj Systems Biology and Applications.2026;[Epub]     CrossRef
  • Creatinine clearance rate predicts all-cause and cardiovascular mortality in patients with MASLD: a Shanghai cohort study
    Yingqi Hou, Yanqiu Huang, Chenghao Zhang, Wen Gu, Yadan Xu, Shuli Li, Jugang Wu, Jibin Liu, Honglin Liu
    Frontiers in Medicine.2026;[Epub]     CrossRef
  • Metabolic dysfunction-associated steatotic liver disease and acute leukemias – a literature review and future directions
    Tareq Salah, Maximillian Stahl, Jan Philipp Bewersdorf
    Leukemia & Lymphoma.2026; 67(6): 1221.     CrossRef
  • Metabolic dysfunction associated steatotic liver disease: mechanisms, diagnosis, and management in adults
    Tina Reinson, Josh Bilson, Caroline Childs, Ryan M Buchanan, Giovanni Targher, Christopher D Byrne
    BMJ Medicine.2026; 5(1): e002038.     CrossRef
  • XBP1s-Regulated GFPT1 via Facilitating O-GlcNAcylation of FASN S509 Is Involved in Arsenic-Induced MASLD through Promoting Fatty Acid Synthesis in Hepatocytes
    Wenjie Li, Bowen Fan, Han Li, Qiong Du, Jiaheng Lin, Yi Yang, Xiaolin Ding, Haoran Zhang, Haibo Xia, Binafsha Manzoor Syed, Cheng Cheng, Qizhan Liu
    Journal of Agricultural and Food Chemistry.2026; 74(14): 11814.     CrossRef
  • Combination Training Improves Leptin Regulation, Reduces Body Fat, and Increases Skeletal Muscle Mass in Obese Females
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    Physical Education Theory and Methodology.2026; 26(2): 380.     CrossRef
  • Current Trends in the Epidemiology of Obesity and the Association Between Obesity and Metabolic Liver Disease (MASLD/MASH)
    Mirjana Grocic, Madison Nguyen, Arun J. Sanyal
    Diabetes, Obesity and Metabolism.2026; 28(S2): 3.     CrossRef
  • Association of environmental chemical exposure with metabolic dysfunction-associated steatotic liver disease: a cross-sectional and network toxicology analysis
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    European Journal of Medical Research.2026;[Epub]     CrossRef
  • Burden of metabolic dysfunction-associated steatotic liver disease in the Asia-Pacific region from 1990 to 2023
    Xiao-Dong Zhou, Qin-Fen Chen, Giovanni Targher, Christopher D Byrne, Luca Valenti, Mark D Muthiah, Seung Up Kim, Daniel Q Huang, Masato Yoneda, Wenhao Li, Yusuf Yilmaz, Herbert Tilg, Vincent Wai-Sun Wong, Ming-Hua Zheng
    eGastroenterology.2026; 4(1): e100369.     CrossRef
  • Unraveling the Mechanisms of Wuling Powder Against MASLD by Integrated Metabolomics–Gut Microbiota–Serum Pharmacochemistry
    Huan Yang, Yan-Mei Tang, Shao-Cong Han, Peng-Quan Wang, Yu-Xuan Tao, Hui-Qiong Yang, Min Zhang, Min Li, Jie Yu, Xing-Xin Yang
    Pharmaceuticals.2026; 19(4): 557.     CrossRef
  • Crocin II alleviates metabolic dysfunction-associated steatotic liver disease by enhancing autophagic degradation of ANGPTL8
    Rongtian Zhang, Kongdong Li, Ziting Zhao, Xintong Jiang, Rumeng Zhang, Chang Liu, Wenxiang Zhang, Siyu Chen
    Targetome.2026;[Epub]     CrossRef
  • Endocrine disruptors reprogram hepatic metabolic and immune gene networks to promote hepatocellular carcinoma
    Yanggang Hong, Yi Wang, Qingyu Chen, Yirong Wang
    npj Gut and Liver.2026;[Epub]     CrossRef
  • Exercise-responsive skeletal muscle genes mechanistically linked to metabolic dysfunction-associated steatotic liver disease
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    World Journal of Gastroenterology.2026;[Epub]     CrossRef
  • Multimodal assessment of hepatic steatosis heterogeneity: segmental MRI-PDFF and ultrasound attenuation coefficient measurement
    M.M. Zhaivoronok, N.V. Deresh, I. Sporea, O.B. Dynnyk, S.V. Feysa, O.A. Pushkarenko, O.A. Fedusenko, O.V. Shcherbina, N.M. Kobyliak
    INTERNATIONAL JOURNAL OF ENDOCRINOLOGY (Ukraine).2026; 22(2): 103.     CrossRef
  • Metabolic dysfunction-associated steatotic liver disease, biomarkers, and cardiovascular risk factors in children with excess weight
    Elisabeth A. Machado, Beatriz L.C. Themistocles, Jorge M.R. Teixeira, Fernanda M.G. Jannuzzi, Geísa Tomaz, Cecilia L. Oliveira, Isabel R. Madeira, Carlos Terra, Maria das Graças C. Souza, Alexandra Monteiro, Eliete Bouskela, Marise E. Marsillac, Paulo F.
    Jornal de Pediatria.2026; 102(3): 101534.     CrossRef
  • Ubiquitin-Specific Protease 2 (USP2) as a Modulator of Energy Metabolism: A Review of Studies Using Animal and Cellular Models
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    Biomedicines.2026; 14(4): 783.     CrossRef
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    Diabetes, Obesity and Metabolism.2026; 28(6): 5240.     CrossRef
  • Longitudinal performance of vibration controlled transient elastography in pediatric metabolic dysfunction associated steatotic liver disease
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    Journal of Pediatric Gastroenterology and Nutrition.2026; 82(6): 1366.     CrossRef
  • LPCAT3 deficiency Drives phospholipid remodeling and mitochondrial oxidative dysfunction to accelerate MASH-HCC development
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    Journal of Advanced Research.2026;[Epub]     CrossRef
  • Evidence-Based Management of MASLD: GRADE Evaluation of Pharmacological Therapies
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    Pharmaceuticals.2026; 19(4): 605.     CrossRef
  • Studying serum immunoglobulin levels in metabolic dysfunction-associated steatotic liver disease
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    Egyptian Liver Journal.2026;[Epub]     CrossRef
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    Clinical and Experimental Dental Research.2026;[Epub]     CrossRef
  • Endoscopy for Metabolic Diseases
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    Journal of Clinical Medicine.2026; 15(8): 2832.     CrossRef
  • Weekend warrior physical activity pattern and risk of all-cause and cardiovascular mortality among US adults with metabolic dysfunction-associated steatotic liver disease: A prospective cohort study of NHANES 2007–2018
    Mengbiao Cai, Kai Jin, YuLong Wang, Jian Zhu, Changnan Xu, Yi Yang, Zhenxiang Guo
    Science Progress.2026;[Epub]     CrossRef
  • Differential Impact of Metabolic Bariatric Surgery Versus Semaglutide on Adverse Hepatic and Extrahepatic Outcomes in Individuals With Metabolic Dysfunction‐Associated Steatotic Liver Disease and Type 2 Diabetes
    Weronika Stupalkowska, Alex E. Henney, David R. Riley, Eric G. Sheu, Uazman Alam, Daniel J. Cuthbertson
    Diabetes, Obesity and Metabolism.2026; 28(7): 5684.     CrossRef
  • Ferroptosis in MASLD: From molecular mechanisms to therapeutic opportunities
    Xiao-Dong Zhou, Qiong-Yue Fan, Giovanni Targher, Christopher D. Byrne, Wei Xie, Qin-Fen Chen, Yuxing Dong, Fudi Wang, Daolin Tang, Ming-Hua Zheng
    Med.2026; 7(6): 101099.     CrossRef
  • Toxic lipid-induced epigenetic activation of ICAM1 in liver sinusoidal endothelium regulates myeloid-driven fibro-inflammatory response in MASH
    Qianqian Guo, Nantawat Satthawiwat, Akitoshi Sano, Chady Meroueh, Asma Hamdi, Xin Dai, Khaled Warasnhe, Alexander M. Washington, Patrick P. Starlinger, Alex Krivonos, Sheng Cao, Enis Kostallari, Johan W. Jonker, Bart van de Sluis, Feda H. Hamdan, Samar H.
    Hepatology.2026;[Epub]     CrossRef
  • Updates on paediatric MASLD: insights from an endocrine lens
    Natalie Segev, Marialena Mouzaki
    Diabetologia.2026;[Epub]     CrossRef
  • An Integrated Nanozyme‐Exosome Platform for Multi‐Targeted Therapy of Metabolic‐Associated Steatotic Liver Disease
    Kun Yu, Xinwei Li, Yingying Liu, Haonan Zhang, Guojie Liu, Tuo Ji, Yuzhi Gao, Lin Wang, Yuwei Bian, Guohua Chen, Zhiwen Zhao, Feng Wang, Xiaoming Yu, Jiachen He, Xuzhu Gao
    Advanced Healthcare Materials.2026;[Epub]     CrossRef
  • Safety and efficacy of pharmacological interventions for hepatic outcomes of metabolic dysfunction-associated steatotic liver disease: protocol for systematic review and network meta-analysis
    Kiavash Semnani, Farbod Semnani, Seyed Sahab Aarabi, Shirin Esmaeili, Ehsaneh Taheri, Armita Mahdavi-Gorabi, Mohsen Rajabnia, Shirin Djalalinia, Saba Goodarzi, Amir Kasaeian, Mohammad Shadab Siddiqui, Mostafa Qorbani
    BMJ Open.2026; 16(4): e111933.     CrossRef
  • Cholinesterase and the association between hepatic steatosis and liver fibrosis in patients with prior hepatitis E
    Ziteng Wang, Zhe Yu, Wen An, Herui Wei, Jing Luo, Mengqi Li, Lingling He, Jiali Ma, Fan Xiao, Lijuan Sun, Qi Gao, Hui Zhong, Hongshan Wei
    European Journal of Medical Research.2026;[Epub]     CrossRef
  • GLP-1RA plus SGLT2i combination therapy and liver fibrosis progression in MASLD with type 2 diabetes
    Jonggi Choi, Gabby Mitchell, Vy H. Nguyen, Eric Przybyszewski, Jiunn Song, Allison Carroll, Megan Michta, Erik Almazan, Tracey G. Simon, Raymond T. Chung
    Hepatology Communications.2026;[Epub]     CrossRef
  • Analysis of B-Scan Ultrasonography Using Neural Networks to Predict Risk of Fibrosis in Patients With Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)
    Josefine Stansch, Kien Vu Trung, Valentin Blank, Jakob Nikolas Kather, Moritz Herzog, Tobias Seibel, Paul-Henry Koop, Robert Haase, Thomas Berg, Johannes Wiegand, Thomas Karlas
    Ultrasound in Medicine & Biology.2026; 52(7): 1346.     CrossRef
  • Sleeve Gastrectomy Alters Exosomal miR-497-5p Cargo to Ameliorate Metabolic Dysfunction–Associated Steatotic Liver by Targeting GABARAPL1
    Zenghui Li, Chenxu Tian, Mengqin Wang, Zhehong Li, Liang Wang, Zheng Wang, Chengyuan Yu, Dezhong Wang, Dongbo Lian, Nengwei Zhang
    Diabetes, Metabolic Syndrome and Obesity.2026; Volume 19: 1.     CrossRef
  • Hypertension in middle childhood
    Mirjam Močnik, Zala Hrovat, Sonja Golob Jančič, Martina Filipič, Mladen Crnobrnja, Nataša Marčun Varda
    BMC Pediatrics.2026;[Epub]     CrossRef
  • Blood-based non-invasive tests show comparable accuracy in MetALD and MASLD for MRE-defined advanced fibrosis
    Akash Roy, Surabhi Jajodia, Shardhya Chakraborty, Shruti Keyal, Awanish Tewari, Nikhil Sonthalia, Sourish Roy, Rajat Khandelwal, Anand Kulkarni, Uday Chand Ghoshal, Rajender Reddy, Mahesh Kumar Goenka
    BMC Gastroenterology.2026;[Epub]     CrossRef
  • Current Drug Development Pipeline for MASLD and MASH: Focusing on Cardiovascular Comorbidities
    Veronika A. Prikhodko, Sergey V. Okovityi
    Biomedicines.2026; 14(4): 909.     CrossRef
  • Apple polyphenol extract mitigates high-fat diet induced cognitive impairment in C57BL/6 mice via a sex-dependent mechanism
    Jieyu Ma, Jiaxin Li, Le Wang, Jinlin Ma, Shilin Chen, Wenxue Luan, Xintong Tian, Siyuan Shang, Xinli Li
    Food Bioscience.2026; 80: 108892.     CrossRef
  • Current status of research on the risk factors and pathogenesis of metabolic dysfunction-associated steatotic liver disease
    Dan Chen, Lingling Yan, Tong Wu, Junpeng Zhao, Xuebing Xu, Weisong Xu, Hong Zhang, Mingbing Xiao
    Frontiers in Endocrinology.2026;[Epub]     CrossRef
  • Patatin-like phospholipase domain-containing protein 3 rs2896019 and MASLD Susceptibility and Severity in Adults: A Systematic Review and Meta-Analysis of Case–Control Studies
    Wei-Yue Lim, Rosmawati Mohamed, Yuh-Fen Pung, Hak-Keith Leung, Rong-Xiang Ng, Shamsul Mohd Zain
    Metabolic Syndrome and Related Disorders.2026;[Epub]     CrossRef
  • Heterogeneity of hepatic macrophages in MASLD/MASH: Lipid-associated programs, molecular mechanisms, spatial niches, and therapeutic implications
    Kaipeng Hu, Siyuan Liu, Shuyan Sheng, Shaobo Zhang, Binghua Li, Beicheng Sun, Anliang Xia
    iLIVER.2026; 5(2): 100234.     CrossRef
  • Predictors of metabolic dysfunction-associated steatotic liver diseases (MASLD) in Vietnamese population
    Anh Gia Pham, An Vu-Khanh Le, Yen Thi-Hai Pham, Lanh Sy Nguyen, Huong Lan Nguyen, Nghia Chinh Quach, Thau Manh Cao, Hanh Thi Nguyen, Xuan Thanh Thai, Anh Tuan Luong, Thuy Thi Pham, Hai Duy Vu, Hai Thi-Thanh Tran, Lan Thi Le, Hai Vu, Giang Binh Tran, Hung
    Scientific Reports.2026;[Epub]     CrossRef
  • Lactational Western‐Style Fat Exposure in Mice Programs Metabolic Dysfunction‐Associated Steatotic Liver Disease (MASLD) in Male Offspring
    Amy Y. Zhao, Haijing Sun, Leyi Yan, Oyewale Shiyanbola, Dave Bridges, Brigid Gregg
    Molecular Nutrition & Food Research.2026;[Epub]     CrossRef
  • Monocyte reprogramming and trained immunity: Linking metabolism to inflammation in non-alcoholic fatty liver disease
    Stanislav Kotlyarov
    World Journal of Hepatology.2026;[Epub]     CrossRef
  • Exercise as a Metabolic Therapy for MASLD: Beyond Weight Loss Toward Sustainable Exercise Strategies
    Hee-Tae Roh, Ju-Yong Bae
    Medicina.2026; 62(4): 784.     CrossRef
  • Tissue-specific roles of IGFBP2 in glucose and lipid metabolism in obesity-related metabolic diseases
    Xiaoyu Song, Wentao Zhong, Hao Zheng, Xinyang Ou, Dongjin Zheng, Zhuo Li
    Frontiers in Nutrition.2026;[Epub]     CrossRef
  • Outcomes of oral antidiabetic drugs in metabolic dysfunction-associated steatotic liver disease: a nationwide target trial emulation study
    Heejoon Jang, Yeonjin Kim, Yoo Kyoung Lim, Dong Hyeon Lee, Sae Kyung Joo, Bo Kyung Koo, Gi-Ae Kim, Woojoo Lee, Stefano Romeo, Won Kim
    Clinical and Molecular Hepatology.2026; 32(2): 737.     CrossRef
  • High-fat diet, gut dysbiosis, and oxidative stress: A synergistic triangle in metabolic dysfunction-associated steatotic liver disease pathogenesis
    Zi-Rui Zhang, Ling She, Yi-Rong Cao, Yuan-Wen Chen
    World Journal of Hepatology.2026;[Epub]     CrossRef
  • Fibulin-3 as a reliable biomarker of fibrosis in obese subjects with metabolic dysfunction-associated steatotic liver disease
    Allen Anthony Laraño, Silvia Palmisano, Deborah Bonazza, Discipio Marina, Marica Meroni, Anna Ludovica Fracanzani, Lory S Crocè, Claudio Tiribelli, Paola Dongiovanni, Natalia Rosso, Pablo Giraudi
    Annals of Hepatology.2026; : 102206.     CrossRef
  • Alcohol-driven phenotypic transition in MASLD and risk of liver-related events
    Seohui Jang, Jihun Song, Eun Seok Kang, Sangwook Cheon, Taeho Kwak, Yihyun Kim, Seokjin Kong, Jinhyeok Choi, Minjeong Kang, Jaewon Khil, Hye Jun Kim, Jeongin Lee, Hwamin Lee, Seogsong Jeong
    JHEP Reports.2026; 8(7): 101866.     CrossRef
  • Targeting the ASB3-CPT1A axis—a new player in combating metabolic dysfunction-associated steatotic liver disease: Editorial on “Hepatocytic ankyrin repeat and SOCS box protein 3 deficiency alleviates metabolic dysfunction-associated steatotic liver diseas
    Yueying Yang, Ying Yang, Yan Lu
    Clinical and Molecular Hepatology.2026; 32(2): 957.     CrossRef
  • Editorial on “Genome-wide interaction study with body mass index identifies CYP7A1 and GIPR as genetic modulators of metabolic dysfunction-associated steatotic liver disease”
    Julia Kozlitina
    Clinical and Molecular Hepatology.2026; 32(2): 931.     CrossRef
  • Role of MicroRNAs in Precision Hepatology
    Youngwoo Lee, Eunho Choi, Young-Sun Lee
    Journal of Digestive Cancer Research.2026; 14(1): 102.     CrossRef
  • Longitudinal changes in fatty liver index, genetic susceptibility, and incident atrial fibrillation
    Siyang Liu, Houde He, Hualan Chen, Hualin Duan, Ying Sun, Dan Deng, Zihao Gui, Lan Liu, Ningjian Wang, Jie Shen, Heng Wan
    Clinica Chimica Acta.2026; 589: 121028.     CrossRef
  • Bupleuri Radix ameliorates MASLD induced by high-fat diet and circadian disruption in rats: Involvement of the NR1D1–SREBF1/CYP7A1 circadian–metabolic axis
    Shuheng Wang, Shuaidong Bai, Tianhui Zhou, Yukun Wang, Xue Bai, Yiming Wang, Junwen Ma, Xuemei Qin, Xiaoxia Gao
    Journal of Ethnopharmacology.2026; 367: 121770.     CrossRef
  • Comment on “High-normal and abnormal alanine transaminase levels linked to increased risk of hepatoma following treatment for chronic hepatitis C”
    Wen-Rui Li
    Journal of the Formosan Medical Association.2026;[Epub]     CrossRef
  • Calorie restriction mitigates steatotic liver disease in obese rats after bariatric surgery
    Yu-Ning Lin, Chin-Ying Wu, Yin-Ru Hsieh, Yi-Tung Lin, Weu Wang, Chun-Chao Chang, Shih-Yi Huang, Wei-Yu Kao
    Nutrition Research.2026; 151: 52.     CrossRef
  • Fucoxanthin Ameliorates MASLD by Directly Targeting GRP78 to Restore ER Homeostasis and Activate AMPK Signaling
    Lin Zhang, Ruifen Zhang, Yu Wu, Binbin Chen, Chao Wang, Cheng Wang, Zhengshun Wen, Jingui Zhang, Haibin Tong, Liang Hong
    Food Science & Nutrition.2026;[Epub]     CrossRef
  • Familial hypobetalipoproteinemia in pediatric patients with fatty liver: an under-recognized cause
    Nurit Loberman Nachum, Eyal Shteyer, Hofit Cohen, Odelia Chorin, Maya Granot, Batia Weiss
    Frontiers in Medicine.2026;[Epub]     CrossRef
  • The effect of a two-week low glycaemic index, higher fibre diet versus high glycaemic index diet on body composition, ectopic lipids, inflammatory biomarkers, gastrointestinal hormones and gut microbiota in metabolic dysfunction-associated steatotic liver
    Amina A. Al-Awadi, Jane I. Grove, Stephen Bawden, Amrita Vijay, Ana M. Valdes, Penny Gowland, Moira A. Taylor, Guruprasad P. Aithal
    Clinical Nutrition ESPEN.2026; 73: 103306.     CrossRef
  • Di(2-ethylhexyl) phthalate exposure: Association with metabolic associated steatotic liver disease and underlying mechanisms
    Dapeng Yin, Yan Li, Wei Wu, Jiacheng Cheng, Xiaojuan Wang, Junhua He, Yikun Zhu, Jin Li
    Ecotoxicology and Environmental Safety.2026; 317: 120210.     CrossRef
  • Metabolic Dysfunction‐Associated Steatotic Liver Disease and Obesity: Pathogenesis, Diagnostics, Risk Stratification, and Therapeutic Approach
    Beom Kyung Kim
    The Kaohsiung Journal of Medical Sciences.2026;[Epub]     CrossRef
  • Evaluation of Factors Affecting Alpha Fetoprotein Levels in Patients With Hepatocellular Carcinoma in a Large Multicenter Cohort
    Nicole Shu Ying Tang, Ethan Kai Jun Tham, Nicholas Syn, Ken Liu, Gang Chen, Beom Kyung Kim, Mark Muthiah, Takumi Kawaguchi, Asahiro Morishita, Sung Won Lee, Karn Wijarnpreecha, Hirokazu Takahashi, Daniel Q. Huang
    Journal of Gastroenterology and Hepatology.2026; 41(6): 1883.     CrossRef
  • Integrated bioinformatics analysis and experimental validation of SRF as a potential senescence biomarker in MASLD
    Mengyue Li, Chang Gao, Yuhui Shi, Wenyu Peng, Yuan Yin, Bin Lu, Zhang Fu
    Frontiers in Molecular Biosciences.2026;[Epub]     CrossRef
  • The Role of MicroRNAs in the Progression of Metabolic Dysfunction-associated Steatotic Liver Disease
    Jang Hyun Choi
    Journal of Digestive Cancer Research.2026; 14(1): 82.     CrossRef
  • GCSH promotes MASH progression by regulating cuproptosis through the glycine–GSH metabolic pathway
    Xuan Fu, Yunmeng Li, Jing Chen, Baolong Yin, Mahbuba Nasrin, Rui Huo, Shuxin Tian
    Free Radical Biology and Medicine.2026; 252: 1.     CrossRef
  • A Descriptive Analysis of Mediterranean Diet Meal Plans Using the Dietary Inflammatory Index, Dietary Antioxidant Index, and Dietary Lipid Indices: Implications for Dietary Intervention for Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)
    Melvin Bernardino, Claudio Tiribelli, Natalia Rosso
    Nutrients.2026; 18(8): 1281.     CrossRef
  • From Genomic Instability to Epigenetic Signatures: The Evolving Landscape of Circulating Cell‐free DNA in Metabolic Dysfunction‐Associated Steatotic Liver Disease
    Wei‐Yue Lim, Rosmawati Mohamed, Yuh‐Fen Pung, Shamsul Mohd Zain
    Hepatology Research.2026; 56(6): 914.     CrossRef
  • Prediction of trajectories and outcomes in early-stage metabolic dysfunction-associated steatotic liver disease: a narrative review
    Brittany Bromfield, Jeremy Chimene-Weiss, Gregory Gheewalla, Theodore Feldman, Emilie K. Mitten, Piero Portincasa, Gyorgy Baffy
    eClinicalMedicine.2026; 95: 103921.     CrossRef
  • Concerns about the health effects of industrially produced seed oils are without scientific foundation: a scoping narrative review of the clinical and observational evidence
    Matthew Nagra, David M. Goldman, Martha A. Belury, Mark Messina
    Critical Reviews in Food Science and Nutrition.2026; : 1.     CrossRef
  • Neutrophils in Liver Diseases: Functions and Challenging Therapies
    Rui Ma, Haoran Meng, Xiutong Chen, Haiyuan Shen, Li Zuo, Hua Wang
    Seminars in Liver Disease.2026;[Epub]     CrossRef
  • The Degree of Liver Steatosis Is Associated with Abnormally High Serum Levels of Markers of Blood–Brain Barrier Dysfunction and Systemic Inflammation in Patients with Morbid Obesity
    Gabriela Hurtado-Alvarado, Karol Iliana Ávila-Soto, Marlene Monserrat Juárez, Lucía Angélica Méndez-García, Verónica Cevallos-López, Juan Antonio Peralta-Calcaneo, Marcela Esquivel-Velázquez, Antonio González-Chávez, Julio César Zavala-Castillo, Ana Alfar
    Medicina.2026; 62(5): 821.     CrossRef
  • Portal Vein Thrombosis in Cirrhotic Candidates for Liver Transplantation and Its Impact on the Transplant Accessibility
    Simona Parisse, Flaminia Ferri, Adriano De Santis, Fabio Melandro, Mario Corona, Quirino Lai, Pierleone Lucatelli, Gianluca Mennini, Massimo Rossi, Stefano Ginanni Corradini
    Journal of Clinical Medicine.2026; 15(9): 3358.     CrossRef
  • c-FLIP as a master regulator of immune homeostasis and disease mechanisms
    Eliana Urbini, Annalisa Adamo, Yushu Hu, Luca Giacobazzi, Silvia Dusi, Francesco De Sanctis, Carmine Carbone, Davide Gibellini, Sara Pilotto, Vincenzo Corbo, Vincenzo Bronte, Fulvia Vascotto, Stefano Ugel
    Cell Death & Disease.2026;[Epub]     CrossRef
  • Semaglutide 2.4 mg for Obese Patients with MASH: A Cost-Effectiveness Analysis from the Italian NHS Perspective
    Enrico Torre, Sergio Di Matteo, Chiara Martinotti, Giacomo Bruno, Alessandro Cabrino, Emma Fogliati, Andrea Giusti, Marco Barbieri, Luigi Bottaro, Giorgio Colombo
    ClinicoEconomics and Outcomes Research.2026; Volume 18: 1.     CrossRef
  • Clinical differentiation between alcohol-associated and metabolic dysfunction-associated steatotic liver disease: a comparative case report
    Chang-Gue Son
    The Journal of Internal Korean Medicine.2026; 47(1): 70.     CrossRef
  • Bacterial Extracellular Vesicles in Aging: Mechanisms and Therapeutic Prospects
    Junfei Tan, Muhammad Zubair, Lin Zhang, Likang Liu, Kangrong Li, Yihua Wang, Yongmin Yan, Wenyan Xu
    International Journal of Nanomedicine.2026; Volume 21: 1.     CrossRef
  • Elevated liver fat content is independently associated with insulin resistance in people with type 1 diabetes
    Jonathan Mertens, Maarten Spinhoven, Rie Braspenning, Floris Vanhevel, Eveline Dirinck, Christophe De Block, Sven Francque
    JHEP Reports.2026; 8(8): 101887.     CrossRef
  • Metabolic dysfunction-associated steatotic liver disease in cushing’s syndrome: a case controlled FibroScan study
    Tugce Apaydin, Caglayan Keklikkiran, Haluk Tarik Kani, Yusuf Yilmaz, Dilek Gogas Yavuz
    Journal of Endocrinological Investigation.2026;[Epub]     CrossRef
  • Non-Hispanic Black Persons With HIV Have a Lower Risk of Metabolic Dysfunction–Associated Steatotic Liver Disease and Clinically Significant Fibrosis Compared to Non-Hispanic White and Hispanic Individuals
    Tinsay A Woreta, Samer Gawrieh, Laura A Wilson, Yuchen Xin, Eduardo Vilar-Gomez, Kathleen E Corey, Richard K Sterling, Jordan E Lake, Susanna Naggie, Sonya Heath, Holly Crandall, Jennifer C Price, Rohit Loomba, Naga Chalasani, Mark S Sulkowski
    Open Forum Infectious Diseases.2026;[Epub]     CrossRef
  • Development and validation of the HABIT score: a practical and robust tool to predict hepatic steatosis using HbA1c, BMI, and triglycerides in patients with unexplained elevated liver enzymes
    Eike Humbert, Verena Wilkens, Semjon Bugaichuk, Karoline Horvatits, Ansgar W. Lohse, Samuel Huber, Sven Pischke, Thorben Fründt
    Annals of Hepatology.2026; 31(2): 102218.     CrossRef
  • Updated Global Consensus Recommendations for Risk Stratification, Treatment Initiation, and Response Monitoring in Metabolic Dysfunction-Associated Steatotic Liver Disease
    Zobair M. Younossi, Markos Kalligeros, Vincent Wai-Sun Wong, Khalid M. Al-Naamani, Frank Tacke, Emmanouil Tsochatzis, Javier Crespo, Mohamed El-Kassas, Fernando Bril, Marco Arrese, Cyrielle Caussy, C. Wendy Spearman, Amalia Gastaldelli, Mário Guimarães Pe
    Clinical Gastroenterology and Hepatology.2026;[Epub]     CrossRef
  • Overcoming the barriers in the screening, diagnosis, and follow-up of patients with metabolic dysfunction–associated steatotic liver disease (MASLD) and metabolic dysfunction–associated steatohepatitis (MASH)
    Roberto Vettor, Maria Letizia Petroni, Idit Dotan, Gadi Lalazar, Martin Haluzík, C. Wendy Spearman, Joel A. Dave, Faisal Abaalkhail, Salah Abusnana, Ali Alshehri, Radan Bruha, Mariann Harangi, Ahmad Jazzar, Michał Kukla, Shiva Kumar, Vaia Lambadiari, Geor
    Reviews in Endocrine and Metabolic Disorders.2026; 27(2): 213.     CrossRef
  • Advances in Diagnostic and Therapeutic Strategies for Metabolic Dysfunction-Associated Steatotic Liver Disease
    Ryan Njeim, Omar Abureesh, Ali Sohail, Ryan Tam, Liliane Deeb
    Livers.2026; 6(3): 35.     CrossRef
  • The role of the resveratrol-sirtuin axis in the treatment of metabolic dysfunction-associated diseases
    Jiale Yang, Shuping Chen, Tiantian Zeng, Yuxuan Zhang, Zhaoxin Li, Haifang Li
    Exploration of Endocrine and Metabolic Diseases.2026;[Epub]     CrossRef
  • GLP-1 receptor agonist–SGLT-2 inhibitor combination and risk of major adverse liver and cardiovascular outcomes in adults with MASLD and type 2 diabetes
    Xianhua Mao, Hong Fan, Man-Fung Yuen, Ramsey Cheung, Wai-Kay Seto, Mindie H. Nguyen
    Hepatology.2026;[Epub]     CrossRef
  • Relevance of lipid droplets in metabolic dysfunction-associated steatotic liver disease
    Ralf Weiskirchen, Amedeo Lonardo
    Expert Opinion on Therapeutic Targets.2026; 30(5): 473.     CrossRef
  • Weight Loss-Induced Metabolic Remodeling in Metabolic dysfunction-associated steatotic liver disease: A Cohort Study Stratified by Genetic Risk
    J. Troisi, P. Torre, L. Schiavo, B.M. Motta, M. Lombardi, M. Festa, T. Sarcina, M. Masarone, M. Persico
    Clinical Nutrition.2026; 61: 106672.     CrossRef
  • Therapeutic efficacy, biomarker signatures, and translatability of semaglutide in the liver biopsy-confirmed GAN DIO-MASH mouse model
    Jens Bjelke Kristensen, Jacob Nøhr-Meldgaard, Susanne E. Pors, Jenny Norlin, Sanne S. Veidal, Kristian Moss Bendtsen, Kristoffer Niss, Maja W. Andersen, Lea M. Harder, Mathilde Teilmann Dalhoff, Martin Rønn Madsen, Kristoffer Voldum-Clausen, Markus Latta,
    American Journal of Physiology-Gastrointestinal and Liver Physiology.2026; 330(6): G659.     CrossRef
  • Effectiveness of therapeutic strategies based on dietary patterns on cardiovascular and hepatic markers in individuals with metabolic dysfunction-associated steatotic liver disease (MASLD) ‒ A systematic review of clinical trials
    Valeria Antonia Rivera Marín, Camila Sanchez, Andrea Herrera-Santelices, Luisa Amanda Ramírez Araya, Edson Yáñez-Barros, Sebastian Cofré
    Nutrición Hospitalaria.2026;[Epub]     CrossRef
  • Extracellular Vesicle from Chlorella vulgaris Alleviates Hepatic Fibrosis in a Mouse Model of Metabolic Dysfunction-Associated Steatotic Liver Disease Through Modulation of Inflammatory Signaling
    Hinata Harada, Yusuke Ohsaki, Afifah Zahra Agista, Hsin-Jung Ho, Takuo Hirose, Kotaro Yamada, Mutsumi Furukawa, Tomonori Nochi, Wan-Chun Chiu, Ya-Ling Chen, Chiu-Li Yeh, Suh-Ching Yang, Takefumi Mori, Hitoshi Shirakawa
    International Journal of Molecular Sciences.2026; 27(9): 3735.     CrossRef
  • Nitric oxide pathway: Emerging therapeutic strategies for MASLD
    Yanling Zhang, Ying Zhang, Hongjin Chen, Fangfang Qi
    Pathology - Research and Practice.2026; 284: 156516.     CrossRef
  • Distinct Roles of Myeloid‐ and Hepatocyte‐PLA2G6 Deletion in Mice With Metabolic Dysfunction‐Associated Steatotic Liver Disease
    Gang Li, Simone Staffer, Sabine Tuma‐Kellner, Uta Merle, Walee Chamulitrat
    Liver International.2026;[Epub]     CrossRef
  • MASLD Management in Spain: A Nationwide Survey of Gastroenterologists Highlighting Gaps in Risk Assessment and Primary Care Coordination
    Carolina Jiménez-González, Paula Argos Vélez, Lorena Cayón, Ana Belén García-Garrido, Noelia Fontanillas Garmilla, Antonio Cuadrado, Paula Iruzubieta, Javier Crespo
    Journal of Clinical Medicine.2026; 15(9): 3259.     CrossRef
  • Predicting MASLD in People With HIV Using Anthropometric Measures: A Multicenter Cross-Sectional Study
    Jihad Slim, Murad Qirem, Paul Bellafiore, Bereket Tewoldemedhin, Tala B Shahin, Kevin Leyden, Ronald Poblete, Sandhya Nagarakanti, Hugo Vargas
    Open Forum Infectious Diseases.2026;[Epub]     CrossRef
  • Current Trends and Perspectives on Obesity and Metabolic Dysfunction-Associated Steatohepatitis in East Asia
    Soo Lim, Hui Zhou, Wataru Ogawa
    Journal of Obesity & Metabolic Syndrome.2026; 35(2): 130.     CrossRef
  • The gut-liver/bile axis: Gut microbiota and bacterial extracellular vesicles remodeling hepatobiliary pathogenesis
    Siyang Hu, Chunhui He, Kunqi Sun, Hongye Zhou, Xueyan Liu, Hao Wang, Sen Li, Haifeng Yu, Ke Xu, Wei Li
    iScience.2026; 29(5): 115623.     CrossRef
  • Effects of Animal-Based Foods on Metabolic Outcomes in Adults with MASLD and Comorbidities: A Systematic Review of Randomized Controlled Trials (2020–2026)
    Joanna Michalina Jurek, Katarzyna Zablocka-Slowinska, Joanna Pieczynska, Anna Lipert, Helena Clavero-Mestres, Teresa Auguet
    Nutrients.2026; 18(10): 1508.     CrossRef
  • Impact of probiotics and prebiotics on glucose/lipid metabolism in metabolic dysfunction-associated steatotic liver disease: mechanisms and implications
    Yinan Zhao, Ziyan Li, Guoying Yu
    Frontiers in Nutrition.2026;[Epub]     CrossRef
  • Impact of modern glucose-lowering therapies on metabolic dysfunction-associated steatotic liver disease in type 2 diabetes
    A.M. Urbanovych, N.Ya. Sidelnyk, O.Z. Lishchuk
    INTERNATIONAL JOURNAL OF ENDOCRINOLOGY (Ukraine).2026; 22(3): 340.     CrossRef
  • The Economic Burden of Metabolic Dysfunction‐Associated Steatohepatitis (MASH) With Cirrhosis: A Systematic Review
    Jeffrey V. Lazarus, Caroline Freeman, Hannes Hagström, Mazen Noureddin, Riku Ota, Mary E. Rinella, Giada Sebastiani, Fotis Tefos, Zobair M. Younossi
    Liver International Communications.2026;[Epub]     CrossRef
  • Evolving B-mode ultrasound-based techniques for assessing metabolic dysfunction-associated steatotic liver disease: Now and beyond
    Walaa Abdelhamed, Mohamed Elbadry, Mohamed El-Kassas
    Liver Research.2026; 10(2): 109.     CrossRef
  • Comparative effectiveness of tirzepatide versus thiazolidinedione in adults with MASLD: a propensity score-matched cohort study
    Jheng-Yan Wu, Yu-Min Lin, Wan-Hsuan Hsu, Ting-Hui Liu, Ya-Wen Tsai, Po-Yu Huang, Min-Hsiang Chuang, Chih-Cheng Lai
    Frontiers in Pharmacology.2026;[Epub]     CrossRef
  • Association between metabolic dysfunction-associated steatotic liver disease and overactive bladder: A cross-sectional study
    Shengqi Zheng, Xu Cui, Longyao Xu, Hong Chen, Liang Zheng, Chaoming Zhou
    Continence.2026; 18: 102466.     CrossRef
  • Tumor microenvironment and metabolic reprogramming in MASLD-related hepatocellular carcinoma
    Vanilla X. Zhang, Tiffany C.-Y. Yu, Yu M. Tsui, Irene O.-L. Ng
    Trends in Molecular Medicine.2026;[Epub]     CrossRef
  • Trends of metabolic dysfunction-associated steatotic liver disease in Mexico, 1990–2023: insights from the Global Burden of Disease Study
    Israel Rico-Alba, Alberto Retana-Guzmán, Marcela Agudelo-Botero, Claudio Alberto Dávila-Cervantes
    Annals of Hepatology.2026; : 102224.     CrossRef
  • Cross‐Vendor Validation of Proton Density Fat Fraction and T1 Mapping Using a Combined Proton Density Fat Fraction—T1 Phantom
    Jitka Starekova, Sebastian Weingärtner, David R. Rutkowski, Garrett C. Fullerton, Won C. Bae, Hung P. Do, Ananth J. Madhuranthakam, Vadim Malis, Sheng Qing Lin, Suraj D. Serai, Takeshi Yokoo, Scott B. Reeder, Jean H. Brittain, Diego Hernando
    Journal of Magnetic Resonance Imaging.2026;[Epub]     CrossRef
  • ПСИХОЛОГІЧНИЙ СТАН ПАЦІЄНТІВ ЗІ СТЕАТОТИЧНОЮ ХВОРОБОЮ ПЕЧІНКИ, АСОЦІЙОВАНОЮ З МЕТАБОЛІЧНОЮ ДИСФУНКЦІЄЮ, ЗА УМОВ ПОЄДНАННЯ З ГІПЕРУРИКЕМІЄЮ: ПІЛОТНЕ ОДНОЦЕНТРОВЕ КРОС-СЕКЦІЙНЕ ДОСЛІДЖЕННЯ
    Ігор Свінціцький , Валерія Каташинська
    Actual Problems of Nephrology.2026; (36-37): 26.     CrossRef
  • Natural Product Treatment for Metabolic Dysfunction-Associated Steatotic Liver Disease: Targeted Mitochondrial Quality Control
    Jing Liu, Fuxing Li, Qianru Zeng, Wenxiao Hu, Le Yang, Shengping Luo, Fang Lv, Dingxiang Li, Yihui Deng
    Drug Design, Development and Therapy.2026; Volume 20: 1.     CrossRef
  • The Chronic Hepatitis B and Metabolic Dysfunction-Associated Steatotic Liver Disease Paradox: Friend or Foe?
    Shang-Chin Huang, Tai-Chung Tseng
    Gut and Liver.2026; 20(3): 350.     CrossRef
  • KCMF1 promotes MASLD progression via K48-linked ubiquitination and degradation of AMPKα
    Min Tang, Yunqin Ma, Jiaqi Wang, Han Cao, Shuangshuang Yao, Xiaohui Wei, Yijiong Tan, Hua Yang, Yi Lin, Bin Hu, Yang Yu, Jiaying Yang, Yufan Wang, Xingdong Zheng, Xiaofang Tang, Fang Liu, Yongde Peng, Nengguang Fan
    Metabolism.2026; 182: 156651.     CrossRef
  • Liver Disease Diagnosis: Fuzzy c-means and Scoring Ranking Approach
    Gabriel A. Leite, Beatriz Flamia Azevedo, Sofia Ribeiro Ferreira, Maria F. Pacheco, Florbela P. Fernandes, Ana I. Pereira
    SN Computer Science.2026;[Epub]     CrossRef
  • Mitochondrial Dysfunction in MASLD: Evidence in Dietary Models and Potential Therapeutic Interventions
    Elda Cristina Villaseñor-Tapia, Edgar Rubén Mendieta-Condado, David Alejandro Curiel-Pedraza, Edwin Estefan Reza-Zaldívar, Ana Laura Márquez-Aguirre, Venkata Ramireddy Narala
    Biochemistry Research International.2026;[Epub]     CrossRef
  • Protocol for volumetric quantification of intrahepatic triglyceride content in adults with obesity
    Alba Camacho-Cardenosa, Antonio Clavero-Jimeno, Alejandro López-Vázquez, Mara Concepción, José L. Martín-Rodríguez, Idoia Labayen, Jonatan R. Ruiz, Rafael Cabeza
    STAR Protocols.2026; 7(2): 104585.     CrossRef
  • Gut-liver metabolic and enterohormonal remodeling drives progression from metabolic dysfunction-associated steatotic liver disease to steatohepatitis
    Jaclyn A. Rivas, Alexandria C. Murphy, Praveena Prasad, Mahmoud S. Yahia, Siem S. Goitom, Aaron S. Romero, Crystal Madera Enriquez, Brianna B. Maes, Prithvi R. Akepati, Marcus A. Garcia, Fredine T. Lauer, Rama R. Gullapalli, Kristen M. Gonzales, Jessica M
    Metabolism.2026; 181: 156652.     CrossRef
  • Post-Translational Modification Networks in Ferroptosis: Orchestrating Defense, Drug Resistance, and Therapeutic Opportunities in Hepatocellular Carcinoma
    Jie Chen, Lingling Li, Sufang Fang, Haitao Zhou
    Journal of Hepatocellular Carcinoma.2026; Volume 13: 1.     CrossRef
  • Novel Pharmacological and Nanotechnology-Based Therapeutic Strategies for MASLD
    Elda Cristina Villaseñor-Tapia, Adriana Franco-Acevedo, Rebeca Rosas-Campos, Juan Armendariz-Borunda
    Pharmaceutics.2026; 18(5): 584.     CrossRef
  • Improving Care Quality for Metabolic Dysfunction-associated Steatotic Liver Disease Through a Structured Yogic Intervention: Protocol for a Randomised Controlled Trial
    Gautam Panwar, Garima Singh, Kanchan Joshi, Sanjay Gupta, Kuldeep Singh, Vikas Upadhyay
    Annals of Neurosciences.2026;[Epub]     CrossRef
  • The Evolution of MASLD Management: From Revised Nomenclature to Disease-Modifying Therapies
    Karolina Kornatowska, Szymon Kopciał, Mateusz Wiekiera, Adrianna Wiekiera, Paweł Budzik, Mateusz Tyniec, Kamal Morshed
    Gastroenterology Insights.2026; 17(2): 33.     CrossRef
  • Metabolomics-Enhanced Liquid Biopsy Identifies Early Heptocellular Injury in Females with MetALD
    Anika Volkmar, Gregor Mattert, Florian Deisinger, Kornelius Schulze, Asmus Heumann, Werner Dammermann, Selina Strathmeyer, Steffen Heelemann, Thomas Kalinski, Stefan Lüth, Janine Kah
    International Journal of Molecular Sciences.2026; 27(11): 4695.     CrossRef
  • Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD): Clinical Profile, Phenotypes, and Risk Stratification. A Narrative Review
    Zalina Yuryevna Sozaeva, Marina Vsevolodovna Atayeva, Elizaveta Olegovna Salatova, Irina Kazbekovna Alikova, Alexandra Evgenievna Dolgaya, Amin Gasaevich Magomedov, Kamilla Ramisovna Hafsi, Nur-Mukhamed Aslanovich Shomakhov, Elena Mukhadinovna Pshukova, Y
    Journal of Biochemical Technology.2026; 17(2): 30.     CrossRef
  • X-chromosome gene dosage shapes MASLD beyond sex hormones
    Mohamad Jamalinia, Giovanni Targher, Amedeo Lonardo
    Trends in Endocrinology & Metabolism.2026;[Epub]     CrossRef
  • Mediating roles of insulin resistance and inflammatory markers between healthy sleep scores and metabolic dysfunction-associated steatotic liver disease
    Qing-Tao Yu, Yun-Ying Lin, Zi-Hao Gui, Hua-Lin Duan, Jun-Jie Yang, Yuan Meng, Xue-Tao Peng, Lan Liu, Heng Wan, Jie Shen
    World Journal of Gastroenterology.2026;[Epub]     CrossRef
  • Acute Effects of Cannabinoid Combination Therapies in a Western Diet-Induced Murine Model of Metabolic Liver Disease
    Jerome Lian, Mohan Patil, Ricky R. Lareu, Marco Falasca
    International Journal of Molecular Sciences.2026; 27(11): 4872.     CrossRef
  • Dantrolene attenuates steatohepatitis and liver fibrosis by suppressing Ca2+ dysregulation
    Juri Sakamoto, Takeshi Yamamoto, Minami Sato, Ayano Sasakura, Yoshihide Nakamura, Naoomi Tominaga, Masako Inamitsu, Naoki Yamamoto, Taro Takami, Motoaki Sano
    Biochemical and Biophysical Research Communications.2026; 827: 154042.     CrossRef
  • Epigenetic antifibrotic effect of expression of long noncoding RNAs lncR-p21, MEG3, H19 on the development of fibrosis in metabolic dysfunction-associated steatotic liver disease (systematic review and meta-analysis)
    A.E. Abaturov, A.O. Nikulina
    GASTROENTEROLOGY.2026; 60(2): 133.     CrossRef
  • Metabolic dysfunction–associated steatotic liver disease and heart failure with preserved ejection fraction: mechanisms and clinical implications from a heart–liver metabolic axis perspective
    Xuebi Wu, Yongxin Ma, Xueshi Yin, Jianping Liu, Yongheng Zhang
    Frontiers in Pharmacology.2026;[Epub]     CrossRef
  • Impact of severe hepatic iron overload on MR and ultrasound time-harmonic elastography
    Steffen P. Häseli, Jakob Schattenfroh, Tom Meyer, Paul Spiesecke, Tobias Puengel, Florian Roßner, Bernhard Gebauer, Raphael Mohr, Münevver Demir, Frank Tacke, Ingolf Sack, Rolf Reiter
    Journal of the Mechanical Behavior of Biomedical Materials.2026; 180: 107480.     CrossRef
  • Determination of ultrasound diagnostic thresholds for detecting early hepatic steatosis in children: a comparative evaluation of different ultrasound systems using MRI-PDFF as the reference standard
    O.A. Pushkarenko, M.M. Zhaivoronok, O.B. Dynnyk, O.T. Yemets, N.V. Deresh, V.V. Kaliy
    GASTROENTEROLOGY.2026; 60(2): 90.     CrossRef
  • Predictors of Discordance Between Controlled Attenuation Parameter and Magnetic Resonance-Proton Density Fat Fraction in Hepatic Steatosis
    Dong Yun Kim, Hyung-Jin Rhee, Beom Kyung Kim
    Clinical and Translational Gastroenterology.2026;[Epub]     CrossRef
  • Four new amide alkaloids from the fruits of Piper longum and their anti-adipogenic activities
    Xue-Ting Cui, Ling-Yu Li, Jia Liu, Hui-Hui Wang, Tao Zhang, Zhong-Mei Zou
    Journal of Asian Natural Products Research.2026; : 1.     CrossRef
  • Upcycling Agricultural By‐Products: RNA‐Seq‐Based Elucidation of Body Weight‐Independent Hepatoprotective Mechanisms of Cucumis melo var. makuwa Leaf Extract in Diet‐Induced Obese Mice
    Ji Young Hwang, Ji Yun Van, Hyeon Hak Jeong, Yerin Seong, Seokmin Lee, Jaeseong Seo, Bo‐Mi Ryu, Seungjun Lee, Suhyeon Baek, Sanggil Lee, Won‐Kyo Jung, Jae‐Il Kim, Bonggi Lee
    eFood.2026;[Epub]     CrossRef
  • Machine learning-based prediction of hepatocellular carcinoma risk in steatotic liver disease: A nationwide cohort study
    Log Young Kim, Ji Soo Lee, Jeong-Ju Yoo, Eun Ju Cho, Sang Gyune Kim, Young Seok Kim, Tyng-Yuan Jang
    PLOS One.2026; 21(5): e0349593.     CrossRef
  • Rendimiento del puntaje MAFLD-S para el tamizaje no invasivo de esteatosis hepática metabólica en el primer nivel de atención
    J.A. Torres-Díaz, A. Olivas-Martinez, J.A. Ruiz-Manriquez, A. Kammar-García, L.C. Chávez-García, L.F. Uscanga-Domínguez, S.E. Martínez-Vázquez
    Revista de Gastroenterología de México.2026;[Epub]     CrossRef
  • Impact of liver and pancreatic steatosis on behavioral responses in rats under experimental conditions and after cessation of combined exposure to steatogenic factors
    A.M. Halinska, O.A. Maltseva, O.O. Halinskyi
    GASTROENTEROLOGY.2026; 60(2): 82.     CrossRef
  • Emerging Therapeutic Perspectives in Obese Patients with MASLD Leading to Compensated Advanced Chronic Liver Disease
    Roberta Chianetta, Lydia Giannitrapani, Alessio Giuseppe Lipari, Assunta Brunone, Claudia Cannizzo, Roberto Citarrella, Maurizio Soresi, Antonio Liguori, Nadia Panera, Filomena Morisco, Luca Miele, Anna Licata
    Biomolecules.2026; 16(6): 797.     CrossRef
  • EASL position paper on preclinical models of steatotic liver disease
    Suchira Gallage, Rui E. Castro, Jennifer Estall, Ira Tabas, Quentin M. Anstee, Dina G. Tiniakos, Gyongyi Szabo, Jun Yu, Chantal Desdouets, Frank Tacke, Fiona Oakley, Mathias Heikenwalder
    Journal of Hepatology.2026;[Epub]     CrossRef
  • Liver Endothelial Heg1 Signal Limits Hepatic Steatosis via Wnt-Mediated Fatty Acid Oxidation in Hepatocytes
    Xiyun Rao, Qianqian Zhao, Jinbiao Chen, Min Zheng, Mingyue Xing, Yu Feng, Jiayuan Chen, Shichao Zhu, Zhiming Han, Geoffrey W. McCaughan, Xiangjian Zheng
    Cellular and Molecular Gastroenterology and Hepatology.2026; 20(9): 101807.     CrossRef
  • Risk factors for atherosclerotic plaque formation in MASLD patients: insights from cross-sectional and Mendelian randomization analyses
    Wei-hao Peng, Jing Zhang, Yu-hua Ruan, Yan Li, Ye Liu, Ming-jia Dai, Jing-kun Jin, Xue-bin Yan, Fang Ji
    Nutrition, Metabolism and Cardiovascular Diseases.2026; : 104815.     CrossRef
  • Metabolic dysfunction-associated steatotic liver disease: pathogenesis and novel treatment options
    Ruizhe Ren, Xiao Liang, Xiyang Wei
    Molecular Biomedicine.2026;[Epub]     CrossRef
  • Structural characterization of the pectic polysaccharide from corn silk and its protective mechanism against MASLD via regulation of the gut-liver axis
    Haichao Wang, Jiajing Yan, Haolin Jia, Xiaoyan Li, Bingxuan Li, Xuefang Zhang, Shujun Wang, Zheng Li, Yuhong Liu, Yifei Bian
    Carbohydrate Polymers.2026; 388: 125510.     CrossRef
  • Association of Hepatic Steatosis Burden With Microalbuminuria in Patients With Type 2 Diabetes Mellitus: A Cross-Sectional Study
    Komal S Jog, Harini Bopaiah, Guru Yogendra Muthyal, Sai Deepika R
    Cureus.2026;[Epub]     CrossRef
  • Renal Dysfunction Across Etiologies of Chronic Liver Disease: A Cross-Sectional Study From a Tertiary Care Center
    Asha Saranya Rapeti, Rakesh Pilla, Gayathri Chouthai, Abhinav Maharaj Thota, Mrinal Shashidhar, Chaithanya Shanthi Vanamada
    Cureus.2026;[Epub]     CrossRef
  • Steatotic liver disease in Latin America: current views and perspectives
    Francisco Idalsoaga, Luis Antonio Díaz, Francisco Barrera, Adrian Gadano, Claudia P. Oliveira, Juan Pablo Arab, Marco Arrese
    Nature Reviews Gastroenterology & Hepatology.2026;[Epub]     CrossRef
  • Advances in Non-Alcoholic Fatty Liver Disease: Pathophysiology, Diagnosis, and Emerging Therapies
    Ioannis Katsaros, Dimitrios Schizas
    Life.2026; 16(6): 915.     CrossRef
  • Contemporary epidemiology of metabolic dysfunction-associated steatotic liver disease
    Do Han Kim, Donghyun Ko, Aijaz Ahmed, Donghee Kim
    Expert Review of Gastroenterology & Hepatology.2026; 20(6): 603.     CrossRef
  • Post-transplant MASLD: a risk-stratified approach to assessment and personalized management
    He-Yu Huang, Zhong-Qi Fan, Guo-Yue Lv
    Frontiers in Medicine.2026;[Epub]     CrossRef
  • The efficacy of carbohydrate-restricted diets on reducing visceral and liver fat in individuals with overweight and obesity: a systematic review and pairwise and network meta-analyses
    Mousa Khalafi, Aref Habibi Maleki, Mahsa Ehsanifar, Maryam Aghaeinejad, Mohammad Hossein Sakhaei, Sara K. Rosenkranz, Michael E. Symonds, Fatemeh Ramezani
    Critical Reviews in Food Science and Nutrition.2026; : 1.     CrossRef
  • Synbiotics and antioxidants synergistically attenuate disease progression in metabolic dysfunction-associated steatotic liver disease
    Zhilu Xu, Wenyi Zhu, Qiyun Xia, Wenli Huang, Yuanyuan Chi, Haoyu Qi, Oi Yee Pessy Chan, Jessica YL Ching, Francis KL Chan, Nor Norman Chan, Siew C. Ng
    Biomedicine & Pharmacotherapy.2026; 201: 119656.     CrossRef
  • Integrative Multi‐Omics Analysis Elucidates the Progressive Disease Landscape and Reveals Dynamic Protein Biomarkers for MASLD Surveillance
    Kejun Liu, Bozhi Zhang, Yezhen Tang, Zhenyao Tan, Yang Bu, Yongxue Lv
    The FASEB Journal.2026;[Epub]     CrossRef
  • A novel serum metabolite classifier for identifying Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) integrating metabolomics and machine learning
    Binghui Li, Yiru Zhang, Ziyang Li, Zhiyang Chen, Zhe Guo, Weimin Wu, Li Tan, Lini Dong, Xiangyu Zhang, Xing Lyu, Min Hu, Qichen Long
    BMC Gastroenterology.2026;[Epub]     CrossRef
  • Survodutide in adults with obesity and metabolic dysfunction-associated steatotic liver disease: SYNCHRONIZE-MASLD, a randomized, double-blind, placebo-controlled phase 3 trial
    Lee M. Kaplan, Elena Startseva, Carel W. le Roux, Sean Wharton, Biykem Bozkurt, Daniel F. Mazo, Jessica von Schlippenbach, Sandra González Maldonado, Samina Ajaz Hussain, Guy W. Neff, Yaneicy Gonzalez Rojas, Charles Smith, Ramy Younes, Arun J. Sanyal, Ant
    Nature Medicine.2026;[Epub]     CrossRef
  • Bisphenol S induces hepatic steatosis and insulin resistance through AMPK inhibition and endoplasmic reticulum stress
    Vinicius Sepúlveda-Fragoso, Emanuelle Barreto-Reis, Thais de Souza Carvalho-Laureano, Milena Barcza Stockler-Pinto, Eliete Dalla Corte Frantz, Denise Pires de Carvalho, Xavier Palomer, Emma Barroso, Manuel Vázquez-Carrera, Leandro Miranda-Alves, D'Angelo
    Food and Chemical Toxicology.2026; 215: 116222.     CrossRef
  • The association between six heavy metal levels and the risk of liver fibrosis in women without gestational diabetes mellitus
    Juan Yu, Li Wang, Shu-lan Zhu, Min Xiao, Hai-xing Huang, Yan-hong Shao, Qi-chen Bao, Miao-miao Ma, Ying-ying Chen
    The American Journal of the Medical Sciences.2026;[Epub]     CrossRef
  • Strengthening Dietary Antioxidant Capacity in Primary Care: A Low-Cost Strategy to Prevent Metabolic Syndrome and MASLD in Iran
    M Sepehrinia, A Nikparast, J Mirzay Razzaz, Reza Homayounfar
    Iranian Journal of Nutrition Sciences and Food Technology.2026; 20(5): 83.     CrossRef
  • Diversity in metabolic dysfunction-associated steatotic liver disease: a framework for precision medicine
    Donghyun Ko, Jordan Low, Peter Low, Damien Chua, Yock Young Dan, Vincent Chen, Jonathan A. Fallowfield, Timothy J. Kendall, Hirokazu Takahashi, Cheng Han Ng, Nicholas Syn, Mark Muthiah
    npj Gut and Liver.2026;[Epub]     CrossRef
  • Shall You Get an Invasive Examination? An AI-Driven Risk Stratification Model for Individuals with Suboptimal Health Status
    Chia-Yu Lai, Jen Yu, Chieh Lee, Guan-Yu Wang, Shania Andea Perdana, Tsung-Hsing Chen, Ta-Sen Yeh
    Service Science.2026;[Epub]     CrossRef
  • Incorporating Insulin Resistance Biomarkers into Machine Learning Models Enhances Diagnostic Accuracy for Metabolic Dysfunction–Associated Steatotic Liver Disease
    Jingyuan Nie, Jing Zhou, Yuanjia Hu, Changhong Zhang, Pingping Yu, Xun Lei
    Diabetes, Metabolic Syndrome and Obesity.2026; Volume 19: 1.     CrossRef
  • Exposure to Per- and Polyfluoroalkyl Substances and the Risk of Sarcopenia: The Mediating Role of Serum Albumin
    Mingkun Sun, Chu Chu, Kun Zhao, Zhengmin (Min) Qian, Mario Schootman, Stephen Edward McMillin, Jiaxiang Dong, Wenwen Bao, Muhammad Amjad, Haseeb Tufail Moryani, Yang Zhou, Yan Yang, Peipei Wang
    Toxics.2026; 14(6): 478.     CrossRef
  • Non-alcoholic fatty liver disease and Helicobacter pylori infection: problems and solutions. A review
    Elena V. Onuchina
    Consilium Medicum.2026; 28(5): 387.     CrossRef
  • Impact of Volatile Organic Compound Mixtures on Cardiovascular Health in Adults With Metabolic Dysfunction–Associated Fatty Liver Disease: A US Population Study
    Qingping Wu, Meiling Jin, Shan Liu, Yue Wu, Tarek Alshaal
    Indoor Air.2026;[Epub]     CrossRef
  • A Single-Food Substitution Strategy (SFSS) Improves Fat Mass and Metabolic Parameters in MASLD: A Prospective Pilot Study
    Nicole Cerabino, Caterina Bonfiglio, Leonilde Bonfrate, Rosanna Donvito, Pasqua Letizia Pesole, Dolores Stabile, Endrit Shahini, Gianluigi Giannelli
    Nutrients.2026; 18(12): 1873.     CrossRef
  • Limited Agreement of Different Elastography Techniques in Assessing Liver Stiffness in Postmenopausal Women with Early-Stage Metabolic Dysfunction-Associated Steatotic Liver Disease
    Ilias D. Vachliotis, Vasileios Rafailidis, Athanasios D. Anastasilakis, Nikoletta Pyrrou, Stergios A. Polyzos
    Livers.2026; 6(3): 53.     CrossRef
  • Insulin-like growth factor binding proteins in metabolic dysfunction-associated steatotic liver disease
    Kuo Fang, Ji Miao, Guobin Song
    Frontiers in Endocrinology.2026;[Epub]     CrossRef
  • Edible extracellular vesicle-like particles from Exocarpium Citri Grandis: A natural nanoplatform for oral treatment of metabolic dysfunction-associated steatotic liver disease
    Jingxiu Zhao, Tao Huang, Chengshi Fu, Yingjie Xiong, Anran Gao, Kui Wang, Yujia Song, Zanxiang Luo, Xiangyun Teng, Wei Zhao, Jianhua Xu
    International Journal of Biological Macromolecules.2026; 372: 152952.     CrossRef
  • Incidence, prevalence, and prognostic impact of sarcopenia on hepatic and cardiovascular outcomes in non-cirrhotic metabolic dysfunction–associated steatotic liver disease
    Rishi Chowdhary, Manjeet Kumar Goyal, Megh Patel, Rahul Chowdhary, Kirti Arora, Varun Mehta, Akash Batta, Omesh Goyal, Ashita Rukmini Vuthaluru
    Frontiers in Epidemiology.2026;[Epub]     CrossRef
  • Liver steatosis and fibrosis in acromegaly patients with active and controlled disease: a scoping review
    Karol P. Sagan, Zuzanna Lipiec-Rzepecka, Martyna Patalong-Wójcik, Michał P. Wasilewicz, Elżbieta Andrysiak-Mamos, Anhelli Syrenicz
    Journal of Endocrinological Investigation.2026;[Epub]     CrossRef
  • Cardiovascular Risk Factors in Greece: Looking Beyond the Classics. A narrative review.
    George Michas, Grigorios Trikas, Athanasios Trikas
    Hellenic Journal of Cardiology.2026;[Epub]     CrossRef
  • Discordant high remnant cholesterol with LDL-C increases the metabolic dysfunction-associated steatotic liver disease risk in patients with type 2 diabetes mellitus
    Ying Zhao, Zhaoyue Li, Tian Yu, Yan Yang, Tingting Du
    BMJ Open Diabetes Research & Care.2026; 14(3): e005841.     CrossRef
  • Prevalence and Predictors of MASLD and Fibrosis in an Urban Outpatient Setting: A Cross-Sectional Study
    Nicolás Ortiz-López, Daniela Simian, Máximo Cattaneo, Katherine Rojas, Daniel Durán, Martina Contreras, Diego Lizama, María Fernanda Eyssautier, Camila Meza, Catalina Molina, Gerardo Jara, Jaime Poniachik
    Journal of Clinical Medicine.2026; 15(12): 4533.     CrossRef
  • Mortality trends in diabetes with proxy-defined steatotic liver disease in the United States, 1999–2023
    Hongzhou Liu, Ru Wang, Liqin Cui, Linlin Wang, Jia Liu, Yangfan Du, Song Dong, Kaide Xia
    Frontiers in Endocrinology.2026;[Epub]     CrossRef
  • Nanoformulations for obesity-driven MASLD and MASH: Cell-specific hepatic drug delivery, comorbidity outcomes, and translational perspectives
    Polu Picheswara Rao
    Obesity Medicine.2026; 62: 100720.     CrossRef
  • Fatty acid‑activated proton transporter SR4 prevents hepatic steatosis and metabolic alterations in diabetic mice by improving mitochondria function, energy balance and oxidative stress
    James Figarola, Jyotsana Singhal, Sharad Singhal
    Experimental and Therapeutic Medicine.2026; 32(1): 1.     CrossRef
  • Non-Invasive Tests in the Management of Metabolic Dysfunction-Associated Steatotic Liver Disease: From Diagnosis to Treatment Monitoring
    Han Ah Lee, Young Youn Cho, Hyung Joon Kim
    Clinical Ultrasound.2026; 11(1): 1.     CrossRef
  • Selenoprotein P deficiency in MASLD: association with insulin resistance and liver fibrosis: a prospective case-control study
    Mona A Hegazy, Samar Saad Mohamed, Eman H Saad, Ahmed Abdelghani, Dalia Abd el Fattah, Mohamed Ahmed Elsayed Mekki, Mona Fathy, Nora Hassan, Omar Ashoush
    BMC Gastroenterology.2026;[Epub]     CrossRef
  • MASLD and sarcopenia research (2012–2025): a multi-database bibliometric analysis
    Keyan Gao, Liwen Xun, Shalei Hao, Min An, Lingfeng Zuo, Jiayu Wang, Ying Wang, Junhua He
    Frontiers in Nutrition.2026;[Epub]     CrossRef
  • Integrating UHPLC-Q-TOF/MS and multi-omics to elucidate the regulatory mechanisms of Xiong's Shiwei Wendan decoction in MASLD
    Miao Jiang, Qiu Wu, Rong Yu, Zehua Zhang, Ge Wen, Yuan Zhong, Zhoujin Tan, Zhijian Li, Xuejiao Xie
    Journal of Chromatography B.2026; 1281: 125181.     CrossRef
  • Korean red ginseng saponins ameliorate metabolic dysfunction-associated steatohepatitis in mice by inhibiting caspase-11 and NLRP3 inflammasomes
    Eojin Kim, Hee Ryeong Lim, Deok-Hyeong Choi, Young-Su Yi
    Journal of Ginseng Research.2026; : 101075.     CrossRef
  • Assessment of Esophageal and Gastric Varices in Patients With Cirrhosis for Clinical Trials: A Centralized Blinded Evaluation System
    Naim Alkhouri, Raj Vuppalanchi, Mazen Noureddin, Eric Lawitz, Edward Mena, Nadege T. Gunn, Khurram Jamil, Seth Zuckerman, Stephen A. Harrison, Naga Chalasani
    Gastro Hep Advances.2026; 5(8): 101004.     CrossRef
  • Integrating the Fatty Liver Index into Primary Care: A Low-Cost Strategy for Early Identification of Chronic Kidney Disease Risk in Iran
    S Bazmi, M Farjam, J Mirzay Razzaz, matin Sepehrinia, R Homayounfar
    Iranian Journal of Nutrition Sciences and Food Technology.2026; 20(5): 117.     CrossRef
  • Obesity Management in Primary Care: Clinical Approaches and Policy Implications in the Era of Incretin-Based Therapies
    Chung-woo Lee
    Korean Journal of Family Practice.2026; 16(2): 81.     CrossRef
  • A celastrol derivative–based multifunctional nanozyme for oxidative stress scavenging and lipid metabolism regulation in metabolic dysfunction-associated steatotic liver disease
    Haoran Yang, Xue Cui, Kun Yu, Zhiwen Zhao, Longlong Jin, Qing Wang, Huiying Yang, Xinwei Li, Xuzhu Gao, Xianfu Wu
    Biomaterials Advances.2026; 188: 215027.     CrossRef
  • Hepatoprotective effects of the branched-chain fatty acids 12-methylmyristic and 13-methylmyristic against palmitate-induced lipotoxicity
    Sara Rico-Chazarra, Carmen García-Melgares, Inmaculada Ros-Madrid, María A. Martínez-Sánchez, Lidia Sánchez-Alcoholado, Alba Oliva-Bolarín, Virginia E. Fernández-Ruiz, Mercedes Ferrer-Gómez, Antonio J. Ruiz-Alcaraz, Carlos M. Martínez, Adriana Mika, María
    Biomedicine & Pharmacotherapy.2026; 201: 119687.     CrossRef
  • Reshaping the Future of MASLD - From Pathophysiological Mechanisms to New Therapeutic Horizons
    Dimitrios Patoulias, Manfredi Rizzo
    Current Pharmaceutical Design.2026; 32(20): 1537.     CrossRef
  • Steatotic Shadows: The Dark Link Between Metabolic Dysfunction-associated Steatotic Liver Disease and Cancer Risk
    Shakta Mani Satyam, Mohamed El-Tanani, Syed Arman Rabbani, Alaa A. Aljabali, Yahia El-Tanani, Dimitrios Patoulias, Manfredi Rizzo
    Current Pharmaceutical Design.2026; 32(20): 1539.     CrossRef
  • Circulating Estradiol as an Independent Risk Factor for Metabolic Dysfunction–Associated Steatotic Liver Disease and Fibrosis Risk in Women: Evidence From a Multicenter Health-Checkup Cohort
    Hyo Jung Cho, Seong Hee Kang, Hye Yeon Chon, SungA Bae, Eunju Kim, Seong Kyun Na, Su Jin Kim, Dooyeon Kim, Hye Ri Ahn, Huigyeong Kim, Jae Youn Cheong, Soon Koo Baik, Young Kul Jung, Soon Sun Kim, Hyung Joon Yim
    Journal of Korean Medical Science.2026;[Epub]     CrossRef
  • LY6D promotes hepatic steatosis via the GRB2–AMPK–SREBP1 signaling axis
    Qiurong Zhao, Linxin Chen, Sha Xie, Juanjuan Meng, Wei Cui, Yao Wu, Ting Zeng, Huaming Mou, Xiaohe Luo
    International Journal of Obesity.2026;[Epub]     CrossRef
  • The Hepato-Exposome Axis: How Endocrine Disruptors Hijack Liver Receptors to Drive MASLD
    M. Martín-Grau, J.H. Kamstra, T. Hyötyläinen, M. Orešič, Y. Song, N. Veličković, A. Djordjevic, D. Vojnović Milutinović, R.F. Jackson, R. van Vorstenbosch, J. Massart, A. Vidal-Puig, S. Carobbio
    Journal of Hepatology.2026;[Epub]     CrossRef
  • Association of metabolic dysfunction-associated steatotic liver disease trajectories with incident liver cancer: a UK Biobank cohort study
    Ryuk Jun Kwon, Yohwan Lim
    Frontiers in Endocrinology.2026;[Epub]     CrossRef
  • Therapeutic effects and mechanisms of Artemisia species on metabolic diseases: A systematic review
    Naiyu Wang, Minmin Li, Mingjing Lu, Zheng Wang, Hualin Wang, Meiyue Yao, Hailing Ding, Muhammad Shahbaz, Muhammad Ijaz
    Medicine.2026; 105(25): e49379.     CrossRef
  • Dysregulated Lipid Metabolism in Hepatocellular Carcinoma: Mechanisms and Therapeutic Strategies
    Yi Yi, Xi Liu, Xi Zhang, Yongsheng Li, Huakan Zhao
    MedComm – Oncology.2026;[Epub]     CrossRef
  • Fibroblast- and Macrophage-Derived Thrombospondin-1 Orchestrates the Fibroinflammatory Niche in Metabolic Dysfunction-Associated Steatohepatitis-Induced Fibrosis
    Sung Woo Cho, Jung Hoon Cha, Deok Wha Seo, Mi Hyun Kwon, Kwon Yong Tak, Hee Sun Cho, Keungmo Yang, Seo Young Jung, SuHyun Hwangbo, Jae Yong Ryu, Si Hyun Bae, Pil Soo Sung
    Diabetes & Metabolism Journal.2026;[Epub]     CrossRef
  • Quantitative Systems Toxicology Model Predicts Obeticholic Acid‐Associated Liver Injury in Metabolic Dysfunction‐Associated Steatotic Liver Disease
    Abigail K. Mayo, James J. Beaudoin, Jeffrey L. Woodhead, Paul B. Watkins, Kim L. R. Brouwer
    Clinical Pharmacology & Therapeutics.2026;[Epub]     CrossRef
  • Divergent risk profiles for cause-specific mortality in MASLD and MetALD: a nationwide population-based study
    Hyuk Kim, Jeong-Ju Yoo, Young Chang, Jae Young Jang, Tom Ryu, Soung Won Jeong, Sang Gyune Kim, Young Seok Kim, Suyeon Park
    Frontiers in Medicine.2026;[Epub]     CrossRef
  • Therapeutic Effects of Glucagon-like Peptide-1 Receptor Agonists in Non-Alcoholic Fatty Liver Disease: A Systematic Review
    Dina Mahoon, Fares Kellany, Imad Khan, Somieya Khan, Alexandra E. Butler
    International Journal of Molecular Sciences.2026; 27(12): 5618.     CrossRef
  • Stage-dependent dynamics of Apolipoprotein C3 across the spectrum of MASLD
    Eva Katharina Messer, Janett Fischer, Toni Herta, Albrecht Boehlig, Madlen Matz-Soja, Adrienn Tuennemann-Tarr, Susanne Gaul, Ulrich Laufs, Thomas Berg, Pavel Strnad
    PLOS One.2026; 21(6): e0349666.     CrossRef
  • Aging and Western Diet Synergistically Impair Hepatic Thyroid Hormone Signaling to Promote Metabolic Dysfunction‐Associated Steatotic Liver Disease (MASLD) in Mice
    Xinru Zhang, Madhulika Tripathi, Chun Ting Goh, Chee Seng Chan, Anita Boelen, Paul M. Yen, Brijesh Kumar Singh, Eveline Bruinstroop
    Aging Cell.2026;[Epub]     CrossRef
  • Cost‐Effectiveness of Pharmacologic Therapies for Metabolic Dysfunction–Associated Steatohepatitis With Significant Fibrosis in the United States
    Ali A. Abdeen, Turgay Ayer, Aanan Biswas, Chase J. Wehrle, Sobia N. Laique, Ali Aminian
    Diabetes, Obesity and Metabolism.2026;[Epub]     CrossRef
  • Trends in MASLD-related cirrhosis and liver cancer across diverse populations, 2010–2023
    Jialin Wu, Bonan Chen, Fuda Xie, Jiahui Hu, Mingyu Liang, Yang Lyu, Peiyao Yu, Tiejun Feng, Muyang Huang, Canbin Fang, Ka Fai To, Terry Cheuk-Fung Yip, Xingxin Wang, Wei Kang
    Hepatology International.2026;[Epub]     CrossRef
  • Letter to the Editor: Steatotic liver disease in chronic hepatitis C - a marker of systemic risk, not direct-acting antiviral treatment failure
    Abdo Imad El Tawil, Claudia Alexandra Pontes Ivantes
    World Journal of Hepatology.2026;[Epub]     CrossRef
  • Metabolic Dysfunction-Associated Steatotic Liver Disease in Inflammatory Bowel Disease: A Cross-Sectional Study of Prevalence and Associated Factors
    Hüseyin Aykut, Nermin Mutlu Bilgiç, Duygu Demirtaş, Süleyman Sayar, Kamil Özdil
    Metabolites.2026; 16(7): 450.     CrossRef
  • Pharmacological treatment of metabolic dysfunction–associated steatotic liver disease: a narrative review
    Jeong-Hwan Lee, Jeong-Ju Yoo, Sang Gyune Kim, Young Seok Kim
    Journal of the Korean Medical Association.2026; 69(6): 492.     CrossRef
  • Decoding the Gut–Fat–Heart Axis: From Molecular Communication Networks to Clinical Translation Strategies
    Zijin Sun, Wei Shao, Haojia Zhang, Kai Wang, Yongchao Liu, Rui Zhou
    International Journal of Molecular Sciences.2026; 27(12): 5596.     CrossRef
  • Macrophage–neutrophil crosstalk via the Selplg–Sell–YAP axis drives NETosis and MASH-associated liver fibrosis
    Fulin Nian, Chen Wu, Dejun Wu, Yifan Ma, Yueying Chen, Lin Xu, Yuqin Li, Ling Dong, Wujun Xiong
    Hepatology.2026;[Epub]     CrossRef
  • Diagnostic Performance of Ultrasound-Guided Attenuation Parameter (UGAP) for Hepatic Steatosis Assessment: Comparison with MRI-PDFF and Evaluation of Cohort-Derived Thresholds
    Dimitrios Kavvadas, Natalia-Valeria Pentara, Dimitrios Kourdakis, Aris Liakos, Emmanouil Sinakos, Panos Prassopoulos, Vasileios Rafailidis
    Diagnostics.2026; 16(13): 2006.     CrossRef
  • Metabolic Dysfunction Associated Fatty Liver Disease (MAFLD), Metabolic Dysfunction Associated Steatotic Liver Disease (MASLD), Metabolic Associated Steatohepatitis (MASH) and Obesity
    Davor Štimac
    Best Practice & Research Clinical Gastroenterology.2026; : 102116.     CrossRef
  • Ammonia in the crosshairs: microbial targets for metabolic dysfunction–associated steatohepatitis prevention
    Vanessa A. Leone, Arion Kennedy
    Journal of Clinical Investigation.2026;[Epub]     CrossRef
  • Fibrosis and Perinatal Features Correlated with Telomere Shortening in Pediatric Metabolic Dysfunction-Associated Steatotic Liver Disease
    Maria Rita Braghini, Salvatore Daniele Bianco, Marzia Bianchi, Giulia Andolina, Antonella Mosca, Cristiano De Stefanis, Michela Piccione, Paola Francalanci, Clara Balsano, Luca Miele, Tommaso Mazza, Anna Alisi
    Life.2026; 16(7): 1068.     CrossRef
  • The economic burden of MASH: comparison of healthcare resource utilization and costs in patients with probable MASH, without MASH, and with diagnosed MASH
    Caichen Zhong, Nana Boame, Semiu O. Gbadamosi, Maximilian Jara, Rakesh Luthra, Alex Salamun, Yu Hong, Abdalla Aly, Fernando Bril, Mary E. Rinella
    Expert Review of Pharmacoeconomics & Outcomes Research.2026;[Epub]     CrossRef
  • Editorial: Advancing immune research in chronic liver diseases through new approach methodologies
    Sara Massironi, Ana C. Maretti-Mira
    Frontiers in Immunology.2026;[Epub]     CrossRef
  • Association of Sleep Characteristics With Suspected Metabolic Dysfunction-Associated Fatty Liver Disease (MAFLD) Risk Among Adults Attending a Community Health Center
    Tushar Prabhakar, Gahan S Jois, Satya V Singh, Bronica Saini, Adarsh Mohan
    Cureus.2026;[Epub]     CrossRef
  • Vitamin E dosing study (VEDS) in patients with metabolic dysfunction–associated steatotic liver disease with elevated aminotransferases: A multicenter, randomized, placebo-controlled trial
    Srinivasan Dasarathy, Emily P. Mitchell, Laura A. Wilson, Brent A. Neuschwander-Tetri, Naga Chalasani, Jeanne M. Clark, Anna Mae Diehl, Bilal Hameed, Rohit Loomba, Liyun Yuan, Kris V. Kowdley, Arun J. Sanyal
    Hepatology.2026;[Epub]     CrossRef
  • MASH‐Related Liver Cancer Estimates Need Aetiology‐Specific Validation in the Asia‐Pacific Region
    Haoyang Hu
    Liver International.2026;[Epub]     CrossRef
  • Liver fibrosis in metabolic dysfunction-associated steatotic liver disease: epidemiology, risk stratification and therapeutics
    Fuliang Li, Hongmei Li, Dulguun Juramt, Kai Kou, Frank Tacke, Lanlan Chen
    BMJ Open Gastroenterology.2026; 13(1): e002343.     CrossRef
  • Interplay between MASLD, obesity and type 2 diabetes: epidemiology, shared pathways and clinical implications
    Kenneth Tachi, Adwoa Agyei-Nkansah, Yacoba Atiase, Bright Forkuo, Victoria Akosua Agyen-Frimpong
    BMJ Open Gastroenterology.2026; 13(1): e002294.     CrossRef
  • Artificial intelligence predicts sex-specific risk of metabolic dysfunction-associated steatotic liver disease
    Mohamad Jamalinia, Giovanni Targher, Amedeo Lonardo, Seyed Taghi Heydari, Kamran Bagheri Lankarani
    Biology of Sex Differences.2026;[Epub]     CrossRef
  • A carotenoid-rich functional tomato sauce (OsteoCol®) reduces liver fat content in adults with metabolic dysfunction-associated steatotic liver disease: a randomized clinical trial
    Rosario Mare, Yvelise Ferro, Samantha Maurotti, Elisa Mazza, Alberto Castagna, Carmelo Pujia, Francesca Rita Noto, Angelo Galluccio, Angela Mirarchi, Giuseppe Andrea Giampà, Marta Moraca, Tiziana Montalcini, Arturo Pujia
    European Journal of Nutrition.2026;[Epub]     CrossRef
  • Association of the cholesterol-HDL-glucose index with prevalent metabolic dysfunction-associated steatotic liver disease and its incremental metabolic-hepatic assessment value: a hospital-based cross-sectional study
    Ziqian Song, Hao Sun, Cai Wang, Yuantao Qi, Yuan Liu
    Frontiers in Nutrition.2026;[Epub]     CrossRef
  • Apigenin attenuates hepatocyte senescence in metabolic dysfunction-associated steatotic liver disease by targeting the TGF-β signaling pathway
    Lijun Cao, Yongna Zhao
    Cytotechnology.2026;[Epub]     CrossRef
  • A TyG–UHR-based machine learning model for screening lean MAFLD: development and external validation
    Yansong Ji, Hui Zhang, Jingjing Xia, Guilian Chen, Hong Li
    BioMedical Engineering OnLine.2026;[Epub]     CrossRef
  • Intermittent fasting strategies for metabolic dysfunction-associated steatotic liver disease: A systematic review and frequentist network meta-analysis of randomized controlled trials
    Husam Abu Suilik, Ahmed Farid Gadelmawla, Mohamed Rifai, Moayad Alhawi, Abdellrahman Ashour, Hassan Abdalshafy, Omar Abdullah Bataineh, Hazem Rezq, Anas Bani Hani, Ismail Elkhattib, Mohamed Abuelazm
    Clinical Nutrition ESPEN.2026; 75: 103415.     CrossRef
  • Non-alcoholic fatty liver disease: Modern approaches to therapy and possibilities of using tirzepatide
    V. V. Gorban, E. V. Gorban, P. E. Kocherga
    Meditsinskiy sovet = Medical Council.2026; (8): 126.     CrossRef
  • Progression of Metabolic Dysfunction–Associated Steatohepatitis in US Adults Using Linked Records and Claims
    Yestle Kim, Romina Fakhraei, John C. O’Donnell, Karissa Johnston, Melissa Bather, Reem Mustafa, Andrew R. Kennedy, Amreen Dinani
    Gastro Hep Advances.2026; 5(9): 101031.     CrossRef
  • Interactive Roles of Metabolic Dysfunction‐Associated Steatotic Liver Disease and Nutritional Status in the Prognosis of Patients With Hepatocellular Carcinoma After Surgical Resection
    Chun‐Ting Ho, Chien‐An Liu, Chia‐Jung Ho, Yi‐Chen Lin, Shin‐Yu Tsai, Hao‐Jan Lei, Shu‐Cheng Chou, Yi‐Hsiang Huang, Ming‐Chih Hou, Jaw‐Ching Wu, Chien‐Wei Su
    The Kaohsiung Journal of Medical Sciences.2026;[Epub]     CrossRef
  • Comparative performance of insulin resistance-related indices in predicting adverse cardiovascular events among individuals with NAFLD and MASLD: a multi-center cohort study
    Yanqiu Huang, Yadan Xu, Chenghao Zhang, Wen Gu, Yue Li, Haojia Zhang, Tian Wang, Tangyi Su, Yangchen Lhamu, Yichen Chen, Liang Zhou, Lipeng Hao, Yang Yang, Hui Wang
    Cardiovascular Diabetology.2026;[Epub]     CrossRef
  • Piezo1 as a novel therapeutic target of salvianolic acid B for metabolic dysfunction-associated steatotic liver disease
    Yuxue Zhang, Chang Liu, Weiyi He, Wenhui Li, Wentao Duan, Chaofeng Wu, Hui Jia, Jieying Lan, Zeyu Tong, Qiaohui Du, Haiyan Lin, Zhuowei Gao, Wenxia Zhao, Piao Luo, Lei Gao
    Phytomedicine.2026; : 158546.     CrossRef
  • Phellinus igniarius Polysaccharides Ameliorate Nonalcoholic Fatty Liver Disease Through Suppressing SREBP1
    Ying‐Jun Zhang, Kai‐Yue He, Wei‐Tao Yin, Qing‐Chun Zhao, Xiong‐Yan Xiang, Jun‐Qi Li, Zhi‐Feng Zhang, Yong‐Ping Jian, Zhi‐Xiang Xu
    Food Frontiers.2026;[Epub]     CrossRef
  • Development and validation of an explainable machine learning model using routine laboratory biomarkers for identifying prevalent MASLD: Evidence from two observational studies
    Jialin Wu, Wenting Wei, Terry Cheuk-Fung Yip, Xinyi Deng, Bonan Chen, Yang Lyu, Peiyao Yu, Tiejun Feng, Fuda Xie, Ge Zhang, Kangmin Zhuang, Aimin Li, Wei Kang
    Clinical and Experimental Medicine.2026;[Epub]     CrossRef
  • Weight loss and alcohol reduction synergize for hepatic steatosis remission in elderly patients with metabolic alcohol-associated liver disease (MetALD): a retrospective cohort study
    Tianxiang Lin, Xiaoxue Yuan, Yanrong Zhao, Wei Wang, Chen Wu, Song Yang, Yinwei Qiu
    International Journal of Obesity.2026;[Epub]     CrossRef
  • Hepatic and Cardiovascular Outcomes in Primary Biliary Cholangitis With Metabolic‐Dysfunction Associated Steatotic Liver Disease
    Jarell Jie‐Rae Tan, Joo Wei Ethan Quek, Sean Shao Wei Lam, Ming‐Hua Zheng, Christophe Corpechot, Aldo J. Montano‐Loza, Yu Jun Wong
    Liver International.2026;[Epub]     CrossRef
  • A Simple Clinical Prediction Model for Metabolic Dysfunction-Associated Steatotic Liver Disease in Adolescents with Obesity
    Yang Liao, Fei Wang, Ting-Ting Tian, Xiu-Fen Li
    Indian Journal of Pediatrics.2026;[Epub]     CrossRef
  • Esteatosis hepática metabólica en el síndrome cardio-reno-metabólico: la «H» silenciada
    Javier Crespo, Paula Iruzubieta, Tomas de Vega, Jose Luis Calleja
    Medicina Clínica.2026; 166(9): 107536.     CrossRef
  • Association of sleep patterns and disorders with metabolic dysfunction-associated steatotic liver disease and liver fibrosis in contemporary American adults
    Guannan Zong, Wangjia Mao, Ming Wen, Xiaoyun Cheng, Guanghui Liu
    Annals of Hepatology.2025; 30(2): 101583.     CrossRef
  • Phthalates exposure, biological aging, and increased risks of insulin resistance, prediabetes, and diabetes in adults with metabolic dysfunction-associated steatotic liver disease
    Yueru Yang, Shuhui Wan, Linling Yu, Wei Liu, Jiahao Song, Da Shi, Yongfang Zhang, Weihong Chen, Weihong Qiu, Bin Wang
    Diabetes & Metabolism.2025; 51(1): 101602.     CrossRef
  • High-Intensity Interval Training Reduces Liver Enzyme Levels and Improves MASLD-Related Biomarkers in Overweight/Obese Girls
    Wissal Abassi, Nejmeddine Ouerghi, Mohamed Bessem Hammami, Nidhal Jebabli, Moncef Feki, Anissa Bouassida, Katja Weiss, Beat Knechtle
    Nutrients.2025; 17(1): 164.     CrossRef
  • Hepatic Estrogen Receptor Alpha Overexpression Protects Against Hepatic Insulin Resistance and MASLD
    Ester S. Alves, Jessica D. M. Santos, Alessandra G. Cruz, Felipe N. Camargo, Carlos H. Z. Talarico, Anne R. M. Santos, Carlos A. A. Silva, Henrique J. N. Morgan, Sandro L. Matos, Layanne C. C. Araujo, João Paulo Camporez
    Pathophysiology.2025; 32(1): 1.     CrossRef
  • Correlation of sarcopenia with progression of liver fibrosis in patients with metabolic dysfunction-associated steatotic liver disease: a study from two cohorts in China and the United States
    Fan Zhang, Longgen Liu, Wenjian Li
    Nutrition Journal.2025;[Epub]     CrossRef
  • The association between working hours and working type with non-alcoholic fatty liver disease: results from the NHANES 1999-2014
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    Frontiers in Endocrinology.2025;[Epub]     CrossRef
  • Genetic risk amplifies lifestyle effects on hepatic steatosis and its progression: Insights from a population-based cohort
    Xin Zhang, Haili Wang, Chengnan Guo, Shuzhen Zhao, Yi Li, Zhenqiu Liu, Tiejun Zhang
    Digestive and Liver Disease.2025;[Epub]     CrossRef
  • Tetrahydrocurcumin Alleviates Metabolic Dysfunction-Associated Steatohepatitis in Mice by Regulating Serum Lipids, Bile Acids, and Gut Microbiota
    Shang Peng, Moran Meng, Ping Luo, Jiao Liu, Junjun Wang, Yong Chen
    International Journal of Molecular Sciences.2025; 26(3): 895.     CrossRef
  • Novel translational mouse models of metabolic dysfunction-associated steatotic liver disease comparable to human MASLD with severe obesity
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    Molecular Metabolism.2025; 93: 102104.     CrossRef
  • Cigarette Smoke Contributes to the Progression of MASLD: From the Molecular Mechanisms to Therapy
    Jiatong Xu, Yifan Li, Zixuan Feng, Hongping Chen
    Cells.2025; 14(3): 221.     CrossRef
  • Association of high-sensitivity C-reactive protein with hepatic fibrosis in patients with metabolic dysfunction-associated steatotic liver disease
    Yunfei Wu, Guojun Zheng, Fan Zhang, Wenjian Li
    Frontiers in Immunology.2025;[Epub]     CrossRef
  • Liver fibrosis progression analyzed with AI predicts renal decline
    Dan-Qin Sun, Jia-Qi Shen, Xiao-Fei Tong, Ya-Yun Ren, Hai-Yang Yuan, Yang-Yang Li, Xin-Lei Wang, Sui-Dan Chen, Pei-Wu Zhu, Xiao-Dong Wang, Christopher D. Byrne, Giovanni Targher, Lai Wei, Vincent W.S. Wong, Dean Tai, Arun J. Sanyal, Hong You, Ming-Hua Zhen
    JHEP Reports.2025; 7(5): 101358.     CrossRef
  • Lean MASLD and IBD: Exploring the Intersection of Metabolic Dysfunction and the Gut–Liver Axis
    Adrian Rotaru, Remus Stafie, Ermina Stratina, Sebastian Zenovia, Robert Nastasa, Horia Minea, Laura Huiban, Tudor Cuciureanu, Cristina Muzica, Stefan Chiriac, Irina Girleanu, Ana-Maria Singeap, Catalin Sfarti, Carol Stanciu, Anca Trifan
    Life.2025; 15(2): 288.     CrossRef
  • Sex differences in diet-induced MASLD – are female mice naturally protected?
    Jana Meyer, Ana Mendes Teixeira, Sandy Richter, Dean P. Larner, Asifuddin Syed, Nora Klöting, Madlen Matz-Soja, Susanne Gaul, Anja Barnikol-Oettler, Wieland Kiess, Diana Le Duc, Melanie Penke, Antje Garten
    Frontiers in Endocrinology.2025;[Epub]     CrossRef
  • Low HDL cholesterol levels in women and hypertriglyceridemia in men: predictors of MASLD onset in individuals without steatosis
    Tsubasa Tsutsumi, Takumi Kawaguchi, Hideki Fujii, Yoshihiro Kamada, Yuichiro Suzuki, Koji Sawada, Miwa Tatsuta, Tatsuji Maeshiro, Hiroshi Tobita, Takemi Akahane, Chitomi Hasebe, Miwa Kawanaka, Takaomi Kessoku, Yuichiro Eguchi, Hayashi Syokita, Atsushi Nak
    Journal of Gastroenterology.2025; 60(7): 891.     CrossRef
  • Association of High‐Sensitivity Troponins in Metabolic Dysfunction‐Associated Steatotic Liver Disease With All‐Cause and Cause‐Specific Mortality
    Donghee Kim, Pojsakorn Danpanichkul, Karn Wijarnpreecha, George Cholankeril, Aijaz Ahmed
    Alimentary Pharmacology & Therapeutics.2025; 61(11): 1785.     CrossRef
  • A Narrative Review on the Risk Factors and Healthcare Disparities of Type 2 Diabetes
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    Diabetology.2025; 6(4): 25.     CrossRef
  • Metabolic dysfunction-associated steatotic liver disease and malignancies: Unmasking a silent saboteur
    Stergios A. Polyzos, Christos S. Mantzoros
    Metabolism.2025; 168: 156253.     CrossRef
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    Yilong Chen, Shuixiu Bian, Jiamei Le
    Genes.2025; 16(4): 399.     CrossRef
  • Significance of FXR agonists in MASLD treatment: a deep dive into lipid alteration by analytical techniques
    Pirangi Srikanth, Khaja Moinuddin Shaik, Vijay Patibandla, Deepak Kumar, Sukhendu Nandi
    Exploration of Endocrine and Metabolic Diseases.2025;[Epub]     CrossRef
  • Editorial: Chrononutrition and MASLD—Its About Time (Restricted Feeding)!
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    Alimentary Pharmacology & Therapeutics.2025; 61(9): 1565.     CrossRef
  • The socioeconomic and environmental determinants of metabolic dysfunction-associated steatotic liver disease: understanding inequalities in prevalence and outcomes
    Dominika Lorek, Krzysztof Łupina, Wiktoria Bisaga, Dominik Malicki, Weronika Stępień, Laura Kumor, Jakub Janczura
    Korean Journal of Family Medicine.2025; 46(2): 61.     CrossRef
  • Advancing precision medicine in metabolic dysfunction-associated steatotic liver disease
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    Trends in Endocrinology & Metabolism.2025; 36(11): 1000.     CrossRef
  • Use of Hepatoscope 2DTE for non-invasive assessment of liver stiffness among Mexican immigrant adults in a community-based setting
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    Clinics and Research in Hepatology and Gastroenterology.2025; 49(5): 102581.     CrossRef
  • Potential bidirectional communication between the liver and the central circadian clock in MASLD
    Frédéric Gachon, Elisabetta Bugianesi, Gabriele Castelnuovo, Henrik Oster, Julie S. Pendergast, Sara Montagnese
    npj Metabolic Health and Disease.2025;[Epub]     CrossRef
  • Impact of Severity of Metabolism-Related Fatty Liver Disease Based on Pathologic Grading on Outcomes after Sleeve Gastrectomy
    云飞 曲
    Journal of Clinical Personalized Medicine.2025; 04(02): 826.     CrossRef
  • GOLM1 and bile acid synthesis: Correspondence to editorial on “GOLM1 promotes cholesterol gallstone formation via ABCG5-mediated cholesterol efflux in MASH livers”
    Yi-Tong Li, Wei-Qing Shao, Zhen-Mei Chen, Jing Lin, Jin-Hong Chen
    Clinical and Molecular Hepatology.2025; 31(2): e189.     CrossRef
  • Prevalence of steatotic liver disease and associated fibrosis in the general population: An epidemiological survey: Letter to the editor on “Epidemiology of metabolic dysfunction-associated steatotic liver disease”
    Lin Guan, Xinhe Zhang, Shanghao Liu, Xiaolong Qi, Yiling Li
    Clinical and Molecular Hepatology.2025; 31(2): e145.     CrossRef
  • Prognostic impact of body composition in hepatocellular carcinoma patients undergoing interventional and systemic therapy
    Yun Feng, Bingran Yu, Anxiao Liu, Chongpeng Cai, Changming Zhou, Tong Tong, Lu Wang, Qi Pan
    Frontiers in Nutrition.2025;[Epub]     CrossRef
  • The Unequal Burden of Metabolic Dysfunction‐Associated Steatotic Liver Disease in 204 Countries and Territories From 1990 to 2021
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    Liver International.2025;[Epub]     CrossRef
  • Chronic Hepatitis B and MASLD: Growing Awareness and Unmet Clinical Needs
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    Liver International.2025;[Epub]     CrossRef
  • Multi‐Center, Multi‐Vendor Validation of Simultaneous MRI‐Based Proton Density Fat Fraction and R2* Mapping Using a Combined Proton Density Fat Fraction‐R2* Phantom
    Jitka Starekova, David Rutkowski, Won C. Bae, Hung Do, Ananth J. Madhuranthakam, Vadim Malis, Sheng Qing Lin, Suraj Serai, Takeshi Yokoo, Scott B. Reeder, Jean H. Brittain, Diego Hernando
    Journal of Magnetic Resonance Imaging.2025; 62(3): 800.     CrossRef
  • Overcoming barriers to unlock the therapeutic potential of saroglitazar for the management of metabolic dysfunction-associated steatotic liver disease
    Murali Krishna Moka, Deepalaxmi Rathakrishnan, D.K. Sriram, Melvin George
    Clinical Nutrition.2025; 49: 52.     CrossRef
  • Targeting Metabolism: Innovative Therapies for MASLD Unveiled
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    International Journal of Molecular Sciences.2025; 26(9): 4077.     CrossRef
  • Psoriasis, metabolic syndrome and methotrexate: Is this association suitable for a new subcategory in steatotic liver disease?
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    World Journal of Hepatology.2025;[Epub]     CrossRef
  • Evaluating the RESET care program: Advancing towards scalable and effective healthcare solutions for metabolic dysfunction-associated liver disease
    Mariana M Ramírez-Mejía, Froylan D Martínez-Sánchez, Jacqueline Córdova-Gallardo, Nahum Méndez-Sánchez
    World Journal of Hepatology.2025;[Epub]     CrossRef
  • Association between glucose time-in-range and the severity of metabolic dysfunction-associated steatotic liver disease in Chinese adults with type 2 diabetes mellitus
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    BMC Endocrine Disorders.2025;[Epub]     CrossRef
  • Gut microbiota in patients with metabolic, dysfunction-associated steatotic liver disease
    Lissette Duarte, Fabien Magne, Martin Gotteland
    Current Opinion in Clinical Nutrition & Metabolic Care.2025; 28(4): 307.     CrossRef
  • Characteristics of serum bile acid profiles among individuals with metabolic dysfunction-associated steatotic liver disease
    Sheng Lyu, Jiani Yang, Xin Xin, Qinmei Sun, Beiyu Cai, Xin Wang, Ziming An, Jian Sun, Yiyang Hu, Lei Shi, Qin Feng, Xiaojun Gou
    BMC Gastroenterology.2025;[Epub]     CrossRef
  • Harnessing nutrition to combat MASLD: a comprehensive guide to food-based therapeutic strategies
    Claudia Reytor-González, Daniel Simancas-Racines, Martín Campuzano-Donoso, Janeth Castano Jimenez, Náthaly Mercedes Román-Galeano, Gerardo Sarno, Evelyn Frias-Toral
    Food and Agricultural Immunology.2025;[Epub]     CrossRef
  • Association between urinary albumin-to-creatinine ratio and all-cause and cardiovascular-cause mortality among MASLD: NHANES 2001–2018
    Zhengjin Wang, Zhangxin Chen, Hanxu Zhuang
    Frontiers in Nutrition.2025;[Epub]     CrossRef
  • Anthropometric Measures and Mortality Risk in Individuals With Metabolic Dysfunction‐Associated Steatotic Liver Disease (MASLD): A Population‐Based Cohort Study
    Yee Hui Yeo, Yixuan Zhu, Jingli Gao, Shanghao Liu, Wenjing Ni, Fajuan Rui, Xue Bai, Nan Geng, Rui Jin, Elizabeth K. Speliotes, Chao Wu, Junping Shi, Xiaolong Qi, Vincent L. Chen, Philip N. Newsome, Jie Li
    Alimentary Pharmacology & Therapeutics.2025; 62(2): 168.     CrossRef
  • Association of gut microbiota dietary index with metabolic dysfunction-associated steatotic liver disease: the mediating roles of inflammation and body mass index
    Yu Pu, Zongbiao Tan, Yanrui Wu, Suqi Zeng, Haodong He, Jixiang Zhang, Weiguo Dong
    Frontiers in Nutrition.2025;[Epub]     CrossRef
  • Association of sarcopenia and physical activity on the severity of metabolic dysfunction-associated steatotic liver disease among United States adults: NHANES 2017 - 2018
    Xiaodie Wei, Xiaohui Liu, Jinhan Zhao, Yang Zhang, Lixia Qiu, Jing Zhang
    Frontiers in Aging.2025;[Epub]     CrossRef
  • Low carbohydrate and low-calorie diets reduce liver fat and lower brain glutamate and myo-inositol levels in patients with Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)
    Andreana P. Haley, Jack Knight-Scott, Marie Caillaud, Isabelle Gallagher, Jessica Park, Yanrong Li, Tianyu Wang, Hirofumi Tanaka, Jeffrey D. Browning
    Metabolic Brain Disease.2025;[Epub]     CrossRef
  • FGF21 reverses MASH through coordinated actions on the CNS and liver
    Jesse P. Rose, Donald A. Morgan, Andrew I. Sullivan, Xiaorong Fu, Melissa Inigo-Vollmer, Shawn C. Burgess, David K. Meyerholz, Kamal Rahmouni, Matthew J. Potthoff
    Cell Metabolism.2025; 37(7): 1515.     CrossRef
  • Liver cirrhosis in metabolic dysfunction-associated steatohepatitis
    Donghyun Ko, Do Han Kim, Pojsakorn Danpanichkul, Masahito Nakano, Chitchai Rattananukrom, Karn Wijarnpreecha, Cheng Han Ng, Mark D Muthiah
    Gastroenterology Report.2025;[Epub]     CrossRef
  • From liver to limb: Exploring the association between fatty liver disease and peripheral artery disease—A systematic review
    Vera Ciornolutchii, Abdulrahman Ismaiel, Jennifer Bogdan, Stefan‐Lucian Popa, Teodora Surdea‐Blaga, Dan L. Dumitrascu
    European Journal of Clinical Investigation.2025;[Epub]     CrossRef
  • Developing and validating a predictive model for all-cause mortality in patients with metabolic dysfunction-associated steatotic liver disease
    Fan Zhang, Longgen Liu, Wenjian Li
    Diabetology & Metabolic Syndrome.2025;[Epub]     CrossRef
  • The Roles of T Cells in the Development of Metabolic Dysfunction‐Associated Steatohepatitis
    Zhifa Ge, Qingwei Wu, Chengyu Lv, Qifeng He
    Immunology.2025; 176(2): 145.     CrossRef
  • Chronic Inflammation and Immune Dysregulation in Metabolic-Dysfunction-Associated Steatotic Liver Disease Progression: From Steatosis to Hepatocellular Carcinoma
    Young-Min Jee, Jeong-Yoon Lee, Tom Ryu
    Biomedicines.2025; 13(5): 1260.     CrossRef
  • Pruritus and Fatigue in Patients With Metabolic Dysfunction-Associated Steatotic Liver Disease: A Study of Turkish Patients From the Global NASH/MASH Registry
    Yusuf Yilmaz, Caglayan Keklikkiran, Andrei Racila, Maria Stepanova, Zobair M. Younossi
    Clinical and Translational Gastroenterology.2025; 16(6): e00844.     CrossRef
  • Impact of Metabolic Dysfunction–associated Steatotic Liver Disease on Cardiovascular Structure, Function, and the Risk of Heart Failure
    Bhavik Bansal, Fannie Lajeunesse-Trempe, Neil Keshvani, Carl J. Lavie, Ambarish Pandey
    Canadian Journal of Cardiology.2025; 41(9): 1777.     CrossRef
  • Pathogenesis and Treatment of Hepatocellular Carcinoma Associated with Nonalcoholic Steatohepatitis
    舒惟 梁
    Advances in Clinical Medicine.2025; 15(05): 2063.     CrossRef
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    James M. Paik, Kathryn Hobbs, Amolika Gupta, Rand Jamal Alkalbani, Manuel Alexander Reyes, Zobair M. Younossi
    Journal of Clinical Gastroenterology.2025;[Epub]     CrossRef
  • Association between weight fluctuation and the risk of metabolic dysfunction-associated steatotic liver disease
    Jin-Ping Wang, Jia-Yang Wang, Pei-Qi Sun, Xue-Wei Wang, Ze-Ting Yuan, Qin Cao, Shu-Ming Pan, Yuan-Ye Jiang
    World Journal of Hepatology.2025;[Epub]     CrossRef
  • Increased prevalence and risk of atherosclerotic cardiovascular disease in individuals with Type 1 diabetes and metabolic dysfunction-associated steatotic liver disease
    Jonathan Mertens, Jonas Weyler, Eveline Dirinck, Luisa Vonghia, Wilhelmus J. Kwanten, Luc F. Van Gaal, Benedicte Y. De Winter, Sven Francque, Christophe De Block
    Cardiovascular Diabetology.2025;[Epub]     CrossRef
  • The Significance of the Presence of Gilbert's Syndrome in Patients With Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD): A Retrospective Cohort Study
    Arjuna P De Silva, Krishanni Prabagar, Anuradha S Wickramasinghage, Aruni A Wanniarachchi, Dileepa S Ediriweera, Madunil A Niriella, Hithanadura J De Silva
    Cureus.2025;[Epub]     CrossRef
  • GLP-1 and Glucagon Receptor Dual Agonists in the Management of Metabolic Dysfunction-associated Steatotic Disease (MASLD)
    Laura Pagès, Aina Martí-Carretero, Diego Rojo, Clara Sabiote, Farnaz Faninam, Sophia C. Parks, María Martínez-Gómez, M Serra Cusidó, Neda Akhlaghi, Sergio Muñoz-Martínez, Alba Jiménez-Masip, Juan M. Pericàs
    Current Hepatology Reports.2025;[Epub]     CrossRef
  • Challenges in applying MASLD risk algorithms in pregnancy: A call for adaptation and inclusion
    Nina Rodriguez, Cecilia Katzenstein, Marcia Lange, Jeanette Rios, Tatyana Kushner, Rachel Meislin, Emma Rosenbluth, Carin Carroll, Theresa Worthington, Shaelyn O’Hara, Joanne Stone, Sonam Rosberger, Keith Sigel, Rhoda Sperling, Norah A. Terrault
    Journal of Hepatology.2025; 83(5): e236.     CrossRef
  • Immunopathogenic mechanisms and immunoregulatory therapies in MASLD
    Yong He, Yingfen Chen, Shengying Qian, Schalk van Der Merwe, Debanjan Dhar, David A. Brenner, Frank Tacke
    Cellular & Molecular Immunology.2025; 22(10): 1159.     CrossRef
  • Association between trans-palmitoleic acid and metabolic dysfunction-associated steatotic liver disease-related hepatocellular carcinoma: NHANES 1999–2018
    Qirui Li, Luqi Zhan, Qian Li, Shuai Zhu, Shuaihui Liu, He Jiang, Jinlin Cheng, Lanjuan Li
    Frontiers in Nutrition.2025;[Epub]     CrossRef
  • To sleeve or not to sleeve: Validation of liver transplantation with sleeve gastrectomy
    Linda W. Moore, Elizabeth W. Brombosz, R. Mark Ghobrial
    Journal of Hepatology.2025; 83(3): 625.     CrossRef
  • Redefining Diagnosis and Management in Hepatology with Multiparametric Ultrasound
    Yolande Chalmers
    EMJ Hepatology.2025; : 66.     CrossRef
  • Incretins and MASLD: at the Crossroads of Endocrine and Hepatic Disorders
    Marwin A. Farrugia, Enzo Pini, Albert Tran, Nicolas Chevalier, Rodolphe Anty, Philippe Gual
    Current Obesity Reports.2025;[Epub]     CrossRef
  • Steatotic Liver Disease in Older Adults: Clinical Implications and Unmet Needs
    Daniel Clayton-Chubb, William W. Kemp, Ammar Majeed, Peter W. Lange, Jessica A. Fitzpatrick, Karl Vaz, John S. Lubel, Alexander D. Hodge, Joanne Ryan, John J. McNeil, Alice J. Owen, Robyn L. Woods, Stuart K. Roberts
    Nutrients.2025; 17(13): 2189.     CrossRef
  • Metabolic dysfunction-associated steatotic liver disease is associated with the risk of severe liver fibrosis in pediatric population
    Wei Li, Lina Jiang, Meiling Li, Chen Lin, Li Zhu, Bokang Zhao, Yisi Liu, Yan Li, Yiyun Jiang, Shuhong Liu, Ping Liang, Junqi Niu, Jingmin Zhao
    Gastroenterology Report.2025;[Epub]     CrossRef
  • Extracellular Vesicles as Biomarkers in Chronic Hepatobiliary Diseases: An Overview of Their Interplay
    Eleni Myrto Trifylli, Sotirios P. Fortis, Anastasios G. Kriebardis, Nikolaos Papadopoulos, Evangelos Koustas, Panagiotis Sarantis, Spilios Manolakopoulos, Melanie Deutsch
    International Journal of Molecular Sciences.2025; 26(13): 6333.     CrossRef
  • Relationship between metabolic dysfunction-associated steatotic liver disease and sarcopenia: A systematic review and meta-analyses
    Ninglin Xia, Jiwei Wang, Qian Lu, Xue Fan, Zhenzhou Jiang, Qinwei Yu
    Clinical Nutrition ESPEN.2025; 68: 679.     CrossRef
  • Time trends and health inequalities of cirrhosis caused by metabolic Dysfunction-associated steatotic liver disease from 1990 to 2021: A global burden of disease study
    Min Wu, Yifeng Li, Dong Liu, Weinong Wen, Yan Min, Qiang Su, Zhenxiang An, Xiaofang Yang
    Journal of Endocrinological Investigation.2025; 48(11): 2599.     CrossRef
  • Therapeutic horizons in metabolic dysfunction–associated steatohepatitis
    Philip N. Newsome, Rohit Loomba
    Journal of Clinical Investigation.2025;[Epub]     CrossRef
  • High Prevalence of Fatty Liver in Bangladeshi Adolescents and Young Adults with Type 2 Diabetes: Key Predictors and Screening Recommendations
    Kishore Shil, Mashfiqul Hasan, Nusrat Sultana, Sayad Salam, Syeda Mostafa, Muhammad Hasanat
    Diabetes, Metabolic Syndrome and Obesity.2025; Volume 18: 2019.     CrossRef
  • Adipose Tissue Dysfunction and Hepatic Steatosis in New-Onset Diabetes
    Emilia Rusu, Mariana Jinga, Raluca Cursaru, Georgiana Enache, Adrian Costache, Ioana Verde, Andra Nica, Anca Alionescu, Florin Rusu, Gabriela Radulian
    Diabetology.2025; 6(7): 70.     CrossRef
  • Food Nutrients and Bioactive Compounds for Managing Metabolic Dysfunction-Associated Steatotic Liver Disease: A Comprehensive Review
    Erdenetsogt Dungubat, Kohei Fujikura, Masahiko Kuroda, Toshio Fukusato, Yoshihisa Takahashi
    Nutrients.2025; 17(13): 2211.     CrossRef
  • Altered HDL Phospholipid and Fatty Acid Profile in MASLD: A Possible Explanation for the Increased CVD Risk
    Sofia Kartsoli, Christina E. Kostara, Athanasios Papathanasiou, Vasilis Tsimihodimos, Eleni T. Bairaktari, Dimitrios K. Christodoulou
    International Journal of Molecular Sciences.2025; 26(13): 6148.     CrossRef
  • Pan-immune-inflammation value and mortality in the US adult MASLD: a nonlinear NHANES analysis
    Qing Zhou, Jisu Xue, Lu Hao
    BMC Gastroenterology.2025;[Epub]     CrossRef
  • Association between body roundness index and risks of all-cause and cardiovascular mortality in adults with metabolic dysfunction-associated steatotic liver disease: NHANES 1999–2018
    Yanshan Yi, Li Yang
    Frontiers in Nutrition.2025;[Epub]     CrossRef
  • Metabolic dysfunction-associated steatotic liver disease: Mechanisms, metabolic reprogramming, and therapeutic insights
    Wan-Qi Yang, Ling-Ling Xue, Jing-Lin Wang
    World Journal of Gastroenterology.2025;[Epub]     CrossRef
  • Steatosis non-invasive tests accurately predict metabolic dysfunction-associated steatotic liver disease, while fibrosis non-invasive tests fall short: Validation in U.S. adult population
    Ayesha Sualeheen, Sze-Yen Tan, Robin M. Daly, Ekavi Georgousopoulou, Gavin Abbott, Stuart K. Roberts, Jacob George, Elena S. George
    Clinics and Research in Hepatology and Gastroenterology.2025; 49(7): 102649.     CrossRef
  • Quantitative US in Metabolic Dysfunction–Associated Steatotic Liver Disease
    Manjiri Dighe, Manish Dhyani
    Radiology.2025;[Epub]     CrossRef
  • Metabolic dysfunction-associated steatotic liver disease and gastrointestinal cancer risk in youth: is it time to unveil a hidden link?
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    Expert Review of Gastroenterology & Hepatology.2025; : 1.     CrossRef
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    Rahul Kumar, Ashwin Chinala, Dhruv Grandhe, S. Joseph Endicott, Marcus A. Garcia, Matthew J. Campen, Rama R. Gullapalli
    Environmental Pollution.2025; 383: 126844.     CrossRef
  • La alimentación es pieza clave en la patogénesis de la enfermedad hepática esteatósica asociada a disfunción metabólica en la población pediátrica
    R. Vázquez-Frias
    Revista de Gastroenterología de México.2025; 90(3): 347.     CrossRef
  • Non-invasive tests of fibrosis in the management of MASLD: revolutionising diagnosis, progression and regression monitoring
    Gong Feng, Vincent Wai-Sun Wong, Giovanni Targher, Christopher D Byrne, Ming-Hua Zheng
    Gut.2025; 74(10): 1741.     CrossRef
  • Intestinal TM6SF2 and the gut-liver axis in MASLD: new insights
    Markos Kalligeros, Linda L. Henry, Zobair M. Younossi
    Metabolism and Target Organ Damage.2025;[Epub]     CrossRef
  • Pemafibrate Ameliorates Steatotic Liver Disease Regardless of Endothelial Dysfunction in Mice
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    Antioxidants.2025; 14(7): 891.     CrossRef
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    Biomedicine & Pharmacotherapy.2025; 190: 118375.     CrossRef
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    Behavioural Neurology.2025;[Epub]     CrossRef
  • Analysis of gastric electrical rhythm in patients with metabolic dysfunction-associated steatotic liver disease and type 2 diabetes mellitus
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    World Journal of Hepatology.2025;[Epub]     CrossRef
  • Gradual DNA methylation changes reveal transcription factors implicated in metabolic dysfunction-associated steatotic liver disease progression and epigenetic age acceleration
    Evelien Van Dijck, Steven Van Laere, Emilie Logie, Steven Timmermans, Erik Fransen, Joe Ibrahim, Timothy J. Kendall, Jonathan A. Fallowfield, Ligia M. Mateiu, Claude Libert, Guy Van Camp, An Verrijken, Luc Van Gaal, Sven Francque, Wim Van Hul, Wim Vanden
    Clinical Epigenetics.2025;[Epub]     CrossRef
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    Current Issues in Molecular Biology.2025; 47(8): 630.     CrossRef
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    Phytomedicine.2025; 146: 157140.     CrossRef
  • Optimal Vegetable Intake for Metabolic-Dysfunction-Associated Steatotic Liver Disease (MASLD) Prevention: Insights from a South Italian Cohort
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    Nutrients.2025; 17(15): 2477.     CrossRef
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    Liver International.2025;[Epub]     CrossRef
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    Journal of Medicinal Chemistry.2025; 68(16): 17457.     CrossRef
  • Adipokine and Hepatokines in Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD): Current and Developing Trends
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    Biomedicines.2025; 13(8): 1854.     CrossRef
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    Metabolites.2025; 15(8): 528.     CrossRef
  • Association of chronic kidney disease and type 2 diabetes mellitus with metabolic dysfunction-associated steatotic liver disease and liver fibrosis assessed by transient elastography: a cross-sectional study based on NHANES 2017–2020
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    Diabetes Research and Clinical Practice.2025; 227: 112418.     CrossRef
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    Pharmaceutics.2025; 17(8): 1036.     CrossRef
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    Hongpeng Lu, Xiaoyun Ding, Peifei Li
    Journal of International Medical Research.2025;[Epub]     CrossRef
  • Multi-omics integration reveals the impact of mediterranean diet on hepatic metabolism and gut microbiota in mice with metabolic dysfunction-associated steatotic liver disease
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    Frontiers in Nutrition.2025;[Epub]     CrossRef
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    Pharmaceuticals.2025; 18(8): 1196.     CrossRef
  • Non-invasive biomarkers for monitoring portal hypertension in metabolic dysfunction-associated steatotic liver disease (MASLD)
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    Expert Review of Gastroenterology & Hepatology.2025; 19(9): 1021.     CrossRef
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    Pediatric Blood & Cancer.2025;[Epub]     CrossRef
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    Diabetes & Metabolism.2025; 51(6): 101698.     CrossRef
  • MIND diet score and its association with metabolic dysfunction-associated steatotic liver disease and gut microbiota profiles: a cross-sectional study
    Shengbo Yang, Litao Zhang, Mingli Hu, Weina He
    Frontiers in Nutrition.2025;[Epub]     CrossRef
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    International Journal of Molecular Sciences.2025; 26(17): 8426.     CrossRef
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    Food Science & Nutrition.2025;[Epub]     CrossRef
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    Liver International.2025;[Epub]     CrossRef
  • Metabolic Dysfunction-Associated Steatotic Liver Disease as a Risk Factor for Chronic Kidney Disease: A Narrative Review
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    Biomedicines.2025; 13(9): 2162.     CrossRef
  • Mediation analysis of the molecular phenotypes in a severe MASH-like liver injury mouse model
    Zhuolin Song, Volodymyr P Tryndyak, Rose A Willett, Igor P Pogribny, Ivan Rusyn, Fred A Wright
    Toxicological Sciences.2025; 208(1): 155.     CrossRef
  • Patatin-Like Phospholipase Domain-Containing Protein 3 (PNPLA3) rs738409 Variant and Non-Alcoholic Fatty Liver Disease Risk in Vietnamese Working-Age Adults: A Case-Control Study with Metabolic Insights
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    Clinical and Experimental Gastroenterology.2025; Volume 18: 191.     CrossRef
  • Narrative review of metabolic syndrome and its relationships with non-alcoholic fatty liver disease, gonadal dysfunction and obstructive sleep apnea
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    Diabetology & Metabolic Syndrome.2025;[Epub]     CrossRef
  • Metabolic dysfunction-associated steatotic liver disease in patients with prediabetes and type 2 diabetes mellitus
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    Terapevticheskii arkhiv.2025; 97(8): 689.     CrossRef
  • Tirzepatide in metabolic dysfunction-associated steatotic liver disease and steatohepatitis: a novel star on the horizon?
    Amedeo Lonardo, Ralf Weiskirchen
    Exploration of Drug Science.2025;[Epub]     CrossRef
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    Medicina.2025; 61(9): 1527.     CrossRef
  • Steatotic liver disease and cancer: from pathogenesis to therapeutic targets
    Zhihong Yang, Zhenjie Liu, Wanqing Liu, Xiaocheng Charlie Dong
    eGastroenterology.2025; 3(3): e100218.     CrossRef
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    Catheterization and Cardiovascular Interventions.2025; 106(6): 3136.     CrossRef
  • Prenatal Choline Attenuates the Elevated Adiposity and Glucose Intolerance Caused by Prenatal Alcohol Exposure
    Susan M. Smith, Carolyn A. Munson, George R. Flentke, Sandra M. Mooney
    Cells.2025; 14(18): 1429.     CrossRef
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    Liver International.2025;[Epub]     CrossRef
  • MASLD Under the Microscope: How microRNAs and Microbiota Shape Hepatic Metabolic Disease Progression
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    International Journal of Molecular Sciences.2025; 26(17): 8633.     CrossRef
  • Diet is a key factor in the pathogenesis of metabolic dysfunction-associated steatotic liver disease in the pediatric population
    R. Vázquez-Frias
    Revista de Gastroenterología de México (English Edition).2025; 90(3): 347.     CrossRef
  • Exploring the Role of Extra Virgin Olive Oil (EVOO) in MASLD: Evidence from Human Consumption
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    Nutrients.2025; 17(18): 2932.     CrossRef
  • Refining the Classification of Steatotic Liver Disease: Beyond Self-Reported Alcohol Intake
    Won-Mook Choi
    Gut and Liver.2025; 19(5): 639.     CrossRef
  • Immunonutrition: Another Player on the MASLD Field
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    International Journal of Molecular Sciences.2025; 26(18): 8928.     CrossRef
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    Diagnostics.2025; 15(18): 2346.     CrossRef
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    Frank Lin, Ayah Obeid, Mehak Sharma, Parampreet Kaur, Kimberly Chaput, Hammad Liaquat
    JGH Open.2025;[Epub]     CrossRef
  • The Combination Empagliflozin/Metformin Attenuates the Progression of Metabolic Dysfunction-Associated Steatotic Liver Disease in a Diet-Induced Experimental Rat Model
    Oscar René Zambrano-Vásquez, Fernando Cortes-Camacho, Juan Carlos Cabrera-Angeles, Ana Lilia Hernández-Alba, Fernando Enrique García-Arroyo, Jorge Ismael Castañeda-Sánchez, Elena Aréchaga-Ocampo, Omar Emiliano Aparicio-Trejo, Leonardo Del Valle-Mondragón,
    International Journal of Molecular Sciences.2025; 26(18): 9010.     CrossRef
  • Curcumin Attenuates Liver Steatosis via Antioxidant and Anti-Inflammatory Pathways in Obese Patients with Type 2 Diabetes Mellitus: A Randomized Controlled Trial
    Metha Yaikwawong, Khanittha Kamdee, Somlak Chuengsamarn
    International Journal of Molecular Sciences.2025; 26(19): 9286.     CrossRef
  • A Systematic Review and Meta-Analysis of Cannabis Use Frequency and Metabolic Dysfunction-Associated Steatotic Liver Disease: Scapegoat or Healer?
    Néstor Israel Quinapanta Castro, Abdel Bermúdez-del Sol
    Cureus.2025;[Epub]     CrossRef
  • Cumulative Effect of Metabolic Factors on Hepatic Steatosis
    Anna Egresi, Brigitta Kozma, Márton Karácsony, Aladár Rónaszéki, Klára Werling, Barbara Csongrády, Pál Kaposi Novák, Anikó Folhoffer, Attila Szijártó, Krisztina Hagymási
    Diagnostics.2025; 15(18): 2406.     CrossRef
  • A non-apoptotic caspase-8–meteorin pathway in hepatocytes promotes MASH fibrosis
    Xiaobo Wang, Mary P. Moore, Hongxue Shi, Yang Xiao, Jiayu Zhang, Lanuza A. P. Faccioli, Zhiping Hu, Shareef Khalid, Danish Saleheen, Dwayne G. Stupack, Tatiana Kisseleva, Alejandro Soto Gutierrez, Mitchell A. Lazar, Ira Tabas
    Nature Metabolism.2025; 7(10): 2067.     CrossRef
  • The impact of aging on liver health and the development of liver diseases
    Sha Neisha Williams, Wen-Xing Ding
    Hepatology Communications.2025;[Epub]     CrossRef
  • Timosaponin AIII from Anemarrhena asphodeloides binds and inhibits S100A8-mediated neutrophil infiltration and NET formation ameliorates MASH
    Yunfan Bai, Jingxin Ju, Ruishi Xie, Jing Li, Xinyi Zhao, Xiaoxue Fang, Ming Zhu, Xintian Lan, Haoming Luo
    International Immunopharmacology.2025; 166: 115539.     CrossRef
  • Clinacanthus nutans leaf extract prevents metabolic dysfunction-associated steatotic liver (MASL) to metabolic dysfunction-associated steatohepatitis (MASH) progression in western diet-fed C57BL/6 mice
    Nurina Hasanatuludhhiyah, Arifa Mustika, Viskasari Pintoko Kalanjati, Muhammad Miftahussurur, Hirokazu Wakuda, Naoto Uemura
    Pharmacia.2025; 72: 1.     CrossRef
  • The role of hypothalamus in the pathophysiological process of MASLD and advances in drug discovery
    Shizhang Wei, Yuan Dong, Yanping Wang, Guohui Li, Yanling Zhao, Ruimao Zheng
    Pharmacological Research.2025; 221: 107972.     CrossRef
  • BMI mediates the association of CALLY index with liver steatosis and fibrosis
    Si-Hua Wen, Tao Tang, Zheng-Rong Ye
    Scientific Reports.2025;[Epub]     CrossRef
  • Era of metabolic dysfunction-associated steatotic liver disease and impact on the liver donor pool
    Juanita Pérez-Escobar, Aline Huerta-Álvarez, Graciela Elia Castro-Narro, María Isabel Astudillo-Delgado, Paulina Carpinteyro-Espin
    World Journal of Gastroenterology.2025;[Epub]     CrossRef
  • Editorial: Metabolic dysfunction-associated steatotic liver disease (MASLD) - pathogenesis, prevention and treatment
    Stanisław Surma, Łukasz Bułdak
    Frontiers in Endocrinology.2025;[Epub]     CrossRef
  • Comment on ‘Association Between Handgrip Strength and Cardiovascular Disease Risk in MASLD: A Prospective Study From UK Biobank’ by T. S. Lim et al.—Authors' Reply
    Tae Seop Lim, Sujin Kwon, Sung A Bae, Hye Yeon Chon, Seol A. Jang, Ja Kyung Kim, Chul Sik Kim, Seok Won Park, Kyoung Min Kim
    Journal of Cachexia, Sarcopenia and Muscle.2025;[Epub]     CrossRef
  • Advances in understanding the mechanism of noncoding RNA (ncRNA)-mediated regulation of macrophage polarization in NAFLD
    Chang Ge, Yi Yuan, Xiaoning Li, Jianmin Zhang, Jitao Ling, Xuehong Zheng, Yuting Wu, Xin Huang, Pingping Yang, Xiao Liu, Deju Zhang, Jianping Liu, Jing Zhang, Peng Yu
    Biochemical Pharmacology.2025; 242: 117372.     CrossRef
  • Association of serum trace elements with non-invasive fibrosis scores in metabolic dysfunction-associated steatotic liver disease
    Erfan Banisefid, Sahand Karkon Zonouzi, Sina Hamzehzadeh, Zeinab Nikniaz, Seyedehyasmin Moghaddamziabari, Leila Alizadeh
    Scientific Reports.2025;[Epub]     CrossRef
  • Metabolic dysfunction-associated steatotic liver disease: epidemiological trends, risk factors, and the role of gut microbiota in disease progression (a literature review)
    А.А. Antoniv, L.V. Kanovska, O.V. Kaushanska, Yu.M. Yarinich
    INTERNATIONAL JOURNAL OF ENDOCRINOLOGY (Ukraine).2025; 21(6): 656.     CrossRef
  • Preventing false positive imaging diagnosis of HCC: differentiating HCC from mimickers and practical strategies
    Ijin Joo
    Journal of Liver Cancer.2025; 25(2): 217.     CrossRef
  • Real-World Lifestyle Interventions are a Practical Model to Improve Liver Stiffness
    Christopher Kasia, Mary Rinella
    Journal of Clinical and Experimental Hepatology.2025; 15(6): 103201.     CrossRef
  • The effects of different exercise intensities on body composition and cardiovascular risk indicators in children with metabolic syndrome: a RCT network meta-analysis
    Yimin Hu, Juan Ouyang, Yi Xia, Yi Sheng
    BMC Sports Science, Medicine and Rehabilitation.2025;[Epub]     CrossRef
  • Sterile inflammation in MASH: emerging role of extracellular RNA and therapeutic strategies
    Sana Raza, Rukshana Mahamood, Pratik Medhe, Ambuj Shahi, Abhishek Yadav, Archana Tewari, Rohit A. Sinha
    npj Metabolic Health and Disease.2025;[Epub]     CrossRef
  • Obesity-Driven Metabolic Disorders: The Interplay of Inflammation and Mitochondrial Dysfunction
    Wooyoung Choi, Gun Ha Woo, Tae-Hwan Kwon, Jae-Han Jeon
    International Journal of Molecular Sciences.2025; 26(19): 9715.     CrossRef
  • Spatial Transcriptomics and snRNA‐seq Expose CAF Niches Orchestrating Dual Stromal‐Immune Barriers in Hepatocellular Carcinoma
    Yingxue Li, Changxiang Huan, Haoting Sun, Wei Zhang, Zhen Guo, Chuanyu Li, Jia Yao, Zhiqi Zhang, Shizhe Yu, Qiongzhu Dong, Lunxiu Qin, Jinze Li, Lianqun Zhou
    Advanced Science.2025;[Epub]     CrossRef
  • Immunosenescence and metabolic reprogramming in MASLD: an age-dependent immunometabolic vicious cycle and therapeutic opportunities
    Yuxin Xu, Qiuxiang Li, Xuehua Jiao
    Frontiers in Cell and Developmental Biology.2025;[Epub]     CrossRef
  • Sex Hormones and Metabolic Dysfunction-Associated Steatotic Liver Disease
    Ralf Weiskirchen, Amedeo Lonardo
    International Journal of Molecular Sciences.2025; 26(19): 9594.     CrossRef
  • Comparative effectiveness of GLP-1 receptor agonists and dual agonists in the treatment of patients with metabolic dysfunction associated steatohepatitis: a systematic review and meta-analysis
    Meng Li, Jianli Hu, Yip Han Chin, Han Shi Jocelyn Chew, Wenru Wang
    Frontiers in Endocrinology.2025;[Epub]     CrossRef
  • Investigation of the Effect of Isotonic Drinks on Quantitative MRI Markers of the Liver and Spleen
    Natassa N. Pittas, Michael Pavlides, Ferenc E. Mózes
    NMR in Biomedicine.2025;[Epub]     CrossRef
  • Physiological roles of phosphoinositides and inositol phosphates: Implications for metabolic dysfunction-associated steatotic liver disease
    Zhili Cheng, Magdalene K Montgomery
    Clinical Science.2025; 139(19): 1095.     CrossRef
  • Naringin mitigates liver damage in a tissue-engineered liver of metabolic dysfunction-associated steatotic liver disease model by promoting autophagy via the mTOR-ULK1 pathway
    Jihui Jia, Yizhi Zhang, Jing Lin, Zhongping Duan, Yu Chen, Xiaohui Zhang
    Molecular Biology Reports.2025;[Epub]     CrossRef
  • Dietary supplementation with a designer metabolic modulator improves MASLD and associated anxiety in mice
    Agnese Segala, Gaia Favero, Emanuela Bottani, Alice Vetturi, Emirena Garrafa, Edoardo Parrella, Chiara Ruocco, Maurizio Ragni, Rita Rezzani, Enzo Nisoli, Alessandra Valerio
    Frontiers in Pharmacology.2025;[Epub]     CrossRef
  • From Steatosis to Immunosenescence: The Impact of Metabolic Dysfunction on Immune Aging in HIV and Non-HIV Populations
    Carlo Acierno, Maria Frontuto, Giulio Francesco De Stefano, Ana Erezanu, Andrea Limone, Simona Morella, Francesco Picaro, Donatella Palazzo, Michele Gilio
    Biomedicines.2025; 13(10): 2513.     CrossRef
  • Constructing biomimetic microenvironments for liver regeneration
    Yawen Zhu, Wanqi Yang, Zhongxia Wang, Dayu Chen, Jinglin Wang, Haozhen Ren
    Journal of Nanobiotechnology.2025;[Epub]     CrossRef
  • Linear association between the composite dietary antioxidant index and the prevalence of sarcopenia in metabolic dysfunction-associated steatotic liver disease
    Jue Zhang, Huan Shi
    Lipids in Health and Disease.2025;[Epub]     CrossRef
  • Research trends on the quality of life in patients with metabolic dysfunction-associated fatty liver diseases: a scientific metrology study
    Can Huang, Meng Chen, Yanfang Sun, Lin Zhang, Wei Liu
    Frontiers in Nutrition.2025;[Epub]     CrossRef
  • 2025 Clinical Practice Guidelines for Diabetes: Management of Metabolic Dysfunction-Associated Steatotic Liver Disease
    Jaehyun Bae
    The Journal of Korean Diabetes.2025; 26(3): 172.     CrossRef
  • Pharmacotherapy of the metabolically associated fatty liver disease
    E.E. Mulyukova, E.L. Novikova, I.A. Skirdov, K.S. Usmanova, N.V. Yusifzade
    Russian Journal of Preventive Medicine.2025; 28(10): 103.     CrossRef
  • Proton Density Fat Fraction and Its Role in Prediction of Metabolic Dysfunction
    Scott B. Reeder, Jitka Starekova
    Radiology.2025;[Epub]     CrossRef
  • Coffee and Tea Intake Is Inversely Associated With Hepatic Fat Deposition, Iron Deposition, and Fibroinflammation in the General Population
    Zhuoshuai Liang, Xiaoyue Sun, Huizhen Jin, Wenhui Gao, Xinmeng Hu, Yi Cheng, Jikang Shi, Yawen Liu
    Molecular Nutrition & Food Research.2025;[Epub]     CrossRef
  • Hydroxytyrosol Improves Metabolic Dysfunction-Associated Fatty Liver Disease Dependent on the Modulation of Gut Microbiota
    Yuji Xiao, Xue Zhang, Bing Shao, Ziyi Wu, Xiao Li, Dongxin Yi, Tao Li, Tao Yang, Jiaxin Zhu, Tiecheng Huang, Yixue Deng, Tianming Qiu, Guang Yang, Xiance Sun, Ningning Wang
    Journal of Agricultural and Food Chemistry.2025; 73(43): 27450.     CrossRef
  • Hepatocellular carcinoma: modern aspects of interdisciplinary management. Part 1. Epidemiology, risk factors, diagnosis
    Yu.M. Stepanov, N.Yu. Zavhorodnia, O.M. Vlasova
    GASTROENTEROLOGY.2025; 59(3): 206.     CrossRef
  • CT-Based Radiomic Models in Biopsy-Proven Liver Fibrosis Staging: Direct Comparison of Segmentation Types and Organ Inclusion
    Andreea Mihaela Morariu-Barb, Tudor Drugan, Mihai Adrian Socaciu, Horia Stefanescu, Andrei Demirel Morariu, Monica Lupsor-Platon
    Diagnostics.2025; 15(21): 2671.     CrossRef
  • Liver-Related COVID-19 Consequences: Dynamics of Liver Health in 2.5 Years
    Ieva Vanaga, Oksana Kolesova, Aleksandrs Kolesovs, Maija Radzina, Davis Simanis Putrins, Jelena Egle, Sniedze Laivacuma, Jelena Storozenko, Ludmila Viksna
    Journal of Clinical Medicine.2025; 14(21): 7604.     CrossRef
  • Metabolic dysfunction–associated steatotic liver disease alters brain function and behavior: Insights from liver-targeted siRNA therapy
    Teresa Cardoso Delgado, Celia Martín-Cuevas, Ana C. Sánchez Hidalgo, Antonio Gil Gómez, Claudia M. Rejano Gordillo, Jon Landa, Rocío Gallego Durán, Naroa Goikoetxea-Usandizaga, Irene González-Recio, Clàudia Gil-Pitarch, L. Estefanía Zapata-Pavas, Jon Ande
    Science Advances.2025;[Epub]     CrossRef
  • Association of Diet Quality, Dietary Acid Load, and Dietary Antioxidant Index With Cardiometabolic and NAFLD Risk Factors Among Patients With Metabolic Syndrome: A Cross‐Sectional Study
    Bijan Ghobadian, Seyedeh Atiye Shahrokhi, Saman Rezaei Talabon, Vahid Notash, Fatemeh Maleki Sedgi, Mehran Rahimlou
    Food Science & Nutrition.2025;[Epub]     CrossRef
  • Quantitative Approaches to Accelerate MASH Drug Discovery and Development
    Yasmeen Abouelhassan, Shailendra Tallapaka, Ramin Mehrani, Scott Q. Siler, Li Qin, Zeyuan Wang, Maria E. Trujillo
    Clinical Pharmacology & Therapeutics.2025; 118(6): 1378.     CrossRef
  • Mitochondrial transplantation and platelet rich plasma for the treatment of non-alcoholic fatty liver disease
    Manuel Alejandro Vargas-Vargas, Marcela González-Montoya, Olin Torres-Isidro, Omar Ortiz-Avila, Elizabeth Calderón-Cortés, Christian Cortés-Rojo
    World Journal of Hepatology.2025;[Epub]     CrossRef
  • Repurposing levothyroxine for managing metabolic dysfunction-associated steatotic liver disease
    Leonidas H. Duntas, Stergios A. Polyzos, Ulrike Gottwald-Hostalek, Bogumila Urgatz, Paul M. Yen
    Endocrine.2025; 90(3): 1043.     CrossRef
  • Genetic polymorphisms associated with metabolic dysfunction-associated steatotic liver disease and cardiometabolic risk susceptibility in the Chinese Han population
    Mingjia Dai, Yan Li, Jing Zhang, Yuhua Ruan, Ye Liu, Jungui Hao, Fang Ji, Xuebing Yan
    Human Genomics.2025;[Epub]     CrossRef
  • Lipid-lowering mechanism of Swietenia macrophylla king leaves through SREBP-1c/FASN axis and RNA sequencing validation
    Yingwei Liu, Yunpeng Sun, Ting Zhou, Xiao Huang, Guokai Wang, Lijuan Sun
    Food Bioscience.2025; 74: 107860.     CrossRef
  • Reconsidering Cardiovascular Risk Assessment in Patients With MASLD
    Ming Hou
    Liver International.2025;[Epub]     CrossRef
  • From steatosis to cirrhosis: the role of obesity in the progression of liver disease
    Klaudia Nowak, Maria Paluch, Maja Cudzik, Klaudia Syska, Wiktoria Gawlikowska, Jakub Janczura
    Journal of Diabetes & Metabolic Disorders.2025;[Epub]     CrossRef
  • Triglyceride-cholesterol-body weight index associated with the risk of metabolic dysfunction-associated steatotic liver disease: a population-based cross-sectional study
    Li Fan, Yongkang Su, Yue Chen, Ling Xu, Hairong Huang, Chunsheng Lu, Jia Peng, Yingbin Sun, Min Jia
    Frontiers in Nutrition.2025;[Epub]     CrossRef
  • Human genetics of steatotic liver disease: insights into insulin resistance and lipid metabolism
    Rosellina M. Mancina, Luca Valenti, Stefano Romeo
    Nature Metabolism.2025; 7(11): 2199.     CrossRef
  • The transition from NAFLD to MASLD: implications for Diagnosis, Prognosis, and Clinical Management
    Carlo Acierno, Riccardo Nevola, Fannia Barletta, Katarzyna Zielińska, Luca Rinaldi, Ferdinando Carlo Sasso, Caterina Conte, Luigi Elio Adinolfi, Alfredo Caturano
    Exploration of Medicine.2025;[Epub]     CrossRef
  • The effects of salvia hispanica (chia seeds) on insulin sensitivity, hematological inflammatory indices and liver function in obese patients with non-alcoholic fatty liver disease (NAFLD)
    Sara Arefhosseini, Maryam Parimi, Helda Tutunchi, Mehrangiz Ebrahimi-Mameghani
    Nutrition & Metabolism.2025;[Epub]     CrossRef
  • Prevalence and Risk Factors of Metabolic Dysfunction–Associated Steatotic Liver Disease in Patients With Type 2 Diabetes Mellitus at a Tertiary Center in Saudi Arabia: Cross-Sectional Questionnaire Study
    Abdulrahman M Elnasieh, Mohammed Almesned, Akram N Al Hazmi, Atheer Alturki, Faisal I Alhawaidi, Razan K Alhadlq, Maryam Alramadhan, Nasser Alobilan, Yasser Sheikh Qroosh
    JMIR Diabetes.2025; 10: e77772.     CrossRef
  • Differentiating MASL and MASH: Clinical Insights from Comparative Case Reports in MASLD
    Chang-Gue Son
    The Journal of Internal Korean Medicine.2025; 46(4): 954.     CrossRef
  • Multi-omics analysis elucidates the therapeutic mechanisms of the Quzhi formula in metabolic dysfunction-associated steatohepatitis targeting gut microbiota, lipid metabolism, and the role of its metabolite fraxin
    Jiao-Xiang Wu, Yue-Lan Wu, Mei-Fang Li, Nian Liu, Ying Liu, Yan-Ping Huang, Yuan Gan, Xiao-Yu Wang, Hai-Sheng Chai, Jin Xu, Qian Xi, Xi-Rong Guo, Hui-Ming Sheng, Ting-Ting Shen, Qin Zhang
    Frontiers in Pharmacology.2025;[Epub]     CrossRef
  • Implications of the Liver-Gut Axis in Liver Disease: From Mechanisms to Therapeutic Targets
    Mariana M. Ramírez-Mejía, Guadalupe Ponciano-Rodríguez, Nahum Méndez-Sánchez
    Archives of Medical Research.2025; 56(8): 103335.     CrossRef
  • Herbal Medicine for Metabolic Dysfunction-Associated Steatotic Liver Disease: Clinical Effectiveness and Research Trends - A Systematic Review and Meta-Analysis
    Min-jo Seo, Su-na Park, Ji-won Lee, So-rim Kim, Jin-hyun Kim, Min-ji Sun, Geon-sik Kong, Yo-sup Choi
    The Journal of Internal Korean Medicine.2025; 46(4): 774.     CrossRef
  • Primary Human Tissue Models for Metabolic Dysfunction‐Associated Liver Disease ‐ toward Streamlining Drug Discovery with Patient‐Derived Assays
    Sonia Youhanna, Nayere Taebnia, Yingxin Liang, Ningtao Cheng, Yi Wang, Maurice Michel, Volker M. Lauschke
    Advanced Biology.2025;[Epub]     CrossRef
  • The Impact of Liraglutide on Patients With Metabolic Dysfunction–Associated Steatotic Liver Disease
    Jae Eun So, Jaehong Jeong, Jung Pyo Hong, Dong Yun Kim, Jae Seung Lee, Mi Na Kim, Beom Kyung Kim, Jun Yong Park, Do Young Kim, Hye Won Lee, Seung Up Kim
    Journal of Gastroenterology and Hepatology.2025; 40(12): 2976.     CrossRef
  • Remnant cholesterol, low-density lipoprotein cholesterol and atherosclerotic cardiovascular disease in metabolic dysfunction-associated steatotic liver disease: a cohort study
    Di Zhou, Mengge Zhou, Shuohua Chen, Chenlu Yang, Yanhong Wang, Yang Zhou, Shutong Wu, Shouling Wu, Li Wang
    Lipids in Health and Disease.2025;[Epub]     CrossRef
  • Effects of long working hours on metabolic dysfunction-associated steatotic liver disease, with and without increased alcohol intake, in healthy workers: A 10-year cohort study
    Yesung Lee, Woncheol Lee, Anna Di Sessa
    PLOS One.2025; 20(11): e0336569.     CrossRef
  • Association between longitudinal weight change and clinical outcome in individuals with MASLD
    Yu Shi, Ruoqi Zhou, Seung Up Kim, Terry Cheuk-Fung Yip, Emmanuel Tsochatzis, Salvatore Petta, Atsushi Nakajima, Hannes Hagström, Elisabetta Bugianesi, Wah-Kheong Chan, Jérôme Boursier, Boon-Bee George Goh, Arun J. Sanyal, Manuel Romero-Gomez, José Luis Ca
    Hepatology.2025;[Epub]     CrossRef
  • Safety and efficacy of weekly pemvidutide versus placebo for metabolic dysfunction-associated steatohepatitis (IMPACT): 24-week results from a multicentre, randomised, double-blind, phase 2b study
    Mazen Noureddin, Stephen A Harrison, Rohit Loomba, Naim Alkhouri, Naga Chalasani, Muhammad Y Sheikh, Shaheen Tomah, Julio A Gutierrez, Silvia Urbina, John J Suschak, Randy Brown, Ozioma Odili, Jay Yang, Stephine Keeton, Guy Neff, Edward Mena, M Scot Rober
    The Lancet.2025; 406(10520): 2644.     CrossRef
  • Impact of Metabolic Dysfunction-Associated Steatotic Liver Disease on Fatigue and Pruritus in Primary Sclerosing Cholangitis: A U.S. Single-Center Study
    Natalia Rojas-Amaris, Ana Marenco-Flores, Carmen Lara-Romero, Romelia Barba, Denisse Rubio-Cruz, Ximena Parraga, Daniela Goyes, John Esli Medina-Morales, Leandro Sierra, Manuel Romero-Gomez, Michelle Lai, Behnam Saberi, Vilas Patwardhan, Alan Bonder
    Journal of Clinical Medicine.2025; 14(22): 8083.     CrossRef
  • Personalized management of metabolic dysfunction-associated steatotic liver disease
    Zhen Sun, Kui Ming Chan, Haojie Jin
    iLIVER.2025; 4(4): 100207.     CrossRef
  • Beyond Discrete Diagnoses: Conceptualizing Obesity-associated Metabolic Disorders as a Unified, Dynamic Continuum
    Cong Xie, Yulian Yuan, Yunjing Wang, Cong Qi, Wei Wang, Chuan An, Aifeila Aikepaer, Yaofu Zhang, Ge Zhang, Xingzhong Feng, Huijuan Gao
    Current Obesity Reports.2025;[Epub]     CrossRef
  • Immunotherapy versus lenvatinib in advanced hepatocellular carcinoma: The critical role of subgroup analyses
    Tingfeng Huang, Jia-Hao Law, Ningqi Pang, Shichuan Tang
    iLIVER.2025; 4(4): 100208.     CrossRef
  • Plasma Extracellular Vesicles Contain Protein Biomarkers for Capturing Stages of Metabolic Dysfunction-Associated Steatotic Liver Disease: A Preliminary Exploratory Study
    Yakun Li, Koen C. van Son, Sandra Serna-Salas, Justina C. Wolters, Nienke P. M. Wassenaar, Stan Driessen, Anne Linde Mak, Anne-Marieke van Dijk, Veera A. T. Houttu, Julia J. Witjes, Diona Zwirs, Michail Doukas, Joanne Verheij, Robin P. F. Dullaart, Hans B
    Biomolecules.2025; 15(11): 1596.     CrossRef
  • Metabolic Dysfunction‐Associated Steatotic Liver Disease (MASLD): Mechanisms, Clinical Implications and Therapeutic Advances
    Dalia M. Miller, Kiana F. McCauley, Kimberly J. Dunham‐Snary
    Endocrinology, Diabetes & Metabolism.2025;[Epub]     CrossRef
  • Liver Transplantation in the Era of Metabolic Dysfunction–Associated Fatty Liver Disease: Challenges, Ethical Dilemmas, and Future Directions
    Said A. Al-Busafi, Mohammed Eslam
    Transplantology.2025; 6(4): 35.     CrossRef
  • The albumin-to-creatinine ratio predicts and explores potential mediation of mortality in metabolic dysfunction-associated steatotic liver disease in U.S. adults: evidence from NHANES 1999–2018
    Huanjie Zhou, Hao Huang, Huiliu Zhao, Naiqi Pang, Meifang Huang, Chao Ou, Ming Lao
    BMC Gastroenterology.2025;[Epub]     CrossRef
  • Signatures of proteomics and glycoproteomics revealed liraglutide ameliorates MASLD by regulating specific metabolic homeostasis in mice
    Yuxuan Chen, Chendong Liu, Qian Yang, Jingtao Yang, He Zhang, Yong Zhang, Yanruyu Feng, Jiaqi Liu, Lian Li, Dapeng Li
    Journal of Pharmaceutical Analysis.2025; 15(11): 101273.     CrossRef
  • К эпидемиологии жировой болезни печени, связанной с метаболической дисфункцией (систематический обзор литературы)
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    Children's medicine of the North-West.2025; 13(3): 108.     CrossRef
  • The shifting burden of gastrointestinal and liver diseases in Southeast Asia and effective control strategies

    Asian Biomedicine.2025; 19(5): 218.     CrossRef
  • An umbrella meta-analysis of microbial therapy on hepatic steatosis, fibrosis, and liver stiffness in metabolic dysfunction-associated steatotic liver disease
    Gvzalnur Kurban, Xiangjun Chen, Xingyi Jin, Hui Xia, Shaokang Wang, Guiju Sun
    Frontiers in Nutrition.2025;[Epub]     CrossRef
  • Linking bisphenol a exposure to MASLD: insights from network toxicology and machine learning based on NHANES 2005–2012 data
    Jiaquan Yuan, Haoyang Xu, Junhong Gan, Haiyan Zhao
    Toxicology Research.2025;[Epub]     CrossRef
  • Curcumin and Tetrahydrocurcumin as Multi-Organ Modulators of the Adipose Tissue–Gut–Liver Axis: Mechanistic Insights, Therapeutic Potential, and Translational Challenges
    Marina Konaktchieva, Radoslav Stojchevski, Nikola Hadzi-Petrushev, Hristo Gagov, Rositza Konakchieva, Vadim Mitrokhin, Gjoko Kungulovski, Mitko Mladenov, Dimiter Avtanski
    Pharmaceuticals.2025; 18(12): 1791.     CrossRef
  • Ten-Year Atherosclerotic Cardiovascular Disease Risk in Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD): Separate Analyses from Romanian and Italian Cohorts Integrating Metabolic, Hepatic, and Gut–Liver Axis Markers
    Naomi-Adina Ciurea, Cristina Monica Pantea, Paul Grama, Irina-Bianca Kosovski, Ilaria Farella, Simona Bataga, Agostino Di Ciaula, Piero Portincasa
    Journal of Clinical Medicine.2025; 14(23): 8361.     CrossRef
  • Ultra-processed food consumption and the risk of developing metabolic dysfunction-associated steatotic liver disease (MASLD): a five-year prospective cohort study in Iranian adults
    Omid Emami, Ali Nikparast, Matin Sepehrinia, Saeid Hadi, Jalaledin Mirzay Razzaz, Reza Homayounfar
    Journal of Health, Population and Nutrition.2025;[Epub]     CrossRef
  • MASLD: Lipotoxicity and Imaging Parallels from Liver Steatosis to Kidney Injury
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    Life.2025; 15(12): 1805.     CrossRef
  • NAD + in fatty liver disease: mechanistic insights and associated targets
    Yaxin Guo, Yuting Wang, Shiran Wu, Yong Wang, Xinde Liu
    Cell Biology and Toxicology.2025;[Epub]     CrossRef
  • The impact of high fructose corn syrup on liver injury and glucose metabolism: a systematic review
    Zane Z. Yu, Sneha Varahala, Sean L. C. Lim, Maimuna C. Marenah, Julia Wattacheril
    Frontiers in Nutrition.2025;[Epub]     CrossRef
  • Association Between Subclinical Hypothyroidism and MASLD: A Systematic Review and Meta‐Analysis
    Gedion Yilma Amdetsion, Chun-Wei Pan, Hiwot Tebeje, Abhin Sapkota, Shreyas Nandyal, Vikram Kotwal, Fortofoiu Mircea-Catalin
    International Journal of Hepatology.2025;[Epub]     CrossRef
  • Roles of short-chain fatty acids in metabolic dysfunction-associated steatotic liver disease and metabolic dysfunction-associated steatohepatitis
    Chun-Ye Zhang, Shuai Liu, Yu-Xiang Sui, Ming Yang
    World Journal of Hepatology.2025;[Epub]     CrossRef
  • Liver fibrosis index and mortality in metabolic dysfunction–associated steatotic liver disease: a Korean cohort study
    Yesung Lee, Woncheol Lee
    Scientific Reports.2025;[Epub]     CrossRef
  • Macrophage-tregs crosstalk: the “hub” of the immune network in MASLD
    Huihui Zhao, Weili Wang, Pengchao Zhu, Zhaohong Shi
    Frontiers in Immunology.2025;[Epub]     CrossRef
  • Proteolysis targeting chimera degraders target pseudokinases to treat metabolic dysfunction-associated steatohepatitis and fibrosis: Mechanisms and therapeutic insights
    Yibing Wang, Jiajing Peng
    Pharmacological Research.2025; 222: 108054.     CrossRef
  • Metabolic dysfunction-associated steatotic liver disease is associated with androgenetic alopecia in adults with stronger effects in women and unhealthy lifestyles
    Sina Bazmi, Mohammad Saeed Soleimani-Meigoli, Mohammadreza Fardaei, Zahra Mohammadi, Reza Homayounfar, Maryam Kazemi, Babak Pezeshki, Mojtaba Farjam
    Scientific Reports.2025;[Epub]     CrossRef
  • Nutritional and Fasting Strategies for the Management of MASLD/MASH: An Integrative Review
    Diya Tawk, Ghalia Ghader, Yasmina Khatib, Philippe Attieh, Tya Youssef, Mahmoud Othman, Frederic Harb, Sami Azar, Hilda E. Ghadieh
    JGH Open.2025;[Epub]     CrossRef
  • Effects of glucagon-like peptide-1 receptor agonists on patients with metabolic dysfunction-associated steatohepatitis: protocol for a systematic review and sequential meta-analysis
    Mei-jun Wang, Yu-nuo Jiang, Pei-pei Li, Yuan-jie Wu
    Systematic Reviews.2025;[Epub]     CrossRef
  • A network meta-analysis of the clinical efficacy of different dietary patterns in the treatment of adult metabolic dysfunction-associated steatotic liver diseases
    Diwen Yu, Peipei Yu, Wanting Huang, Pengwei Zhang, Li Li
    Clinical Nutrition Open Science.2025; 64: 357.     CrossRef
  • Synergistic Impact of Sarcopenia and T2DM on Mortality in Metabolic Dysfunction‐Associated Steatotic Liver Disease (MASLD)
    Qi Zhou, Peiyan Liu, Lixiang Li, Tengfei Yin, Hao Bai, Yanqing Li
    The FASEB Journal.2025;[Epub]     CrossRef
  • Early-Life Nutritional Determinants of Pediatric MASLD
    Johanna K. DiStefano
    Nutrients.2025; 17(24): 3871.     CrossRef
  • From liver to gut: the hidden gastrointestinal impact of pediatric metabolic dysfunction-associated steatotic liver disease
    Gianmario Forcina, Vittoria Frattolillo, Maria De Cesare, Assunta Floriano, Rosamaria Palma, Federica Casamassima, Mario Bartiromo, Pierluigi Marzuillo, Emanuele Miraglia del Giudice, Anna Di Sessa
    Expert Review of Gastroenterology & Hepatology.2025; 19(12): 1329.     CrossRef
  • The association of multiple metabolic disorders with the severity of fasting blood glucose and hepatic steatosis in a Chinese population with MAFLD: a cross-sectional study of over 3000 participants
    Xue Qu, Shanshan Jin, Yuqing Shi, Weisong Zhang, Delong Cong, Yangyang Liu
    Scientific Reports.2025;[Epub]     CrossRef
  • Changes in liver enzymes and cardiometabolic markers in individuals with obesity and metabolic-dysfunction-associated steatohepatitis treated with semaglutide
    Husam Albarmawi, Firas Dabbous, Abdalla Aly, Alia Yousif, Samuel Huse, Maximilian Jara, Andres Quintero, Eric Lawitz
    Current Medical Research and Opinion.2025; 41(11): 2089.     CrossRef
  • Cross-sectional and longitudinal associations between fatty liver index and kidney function using updated MASLD and CKD–EPI 2021 definitions: a population-based study with region-specific cutoffs
    Sina Bazmi, Mohammadreza Fardaei, Reza Homayounfar, Maryam Kazemi, Babak Pezeshki, Reza Malekzadeh, Nasrollah Ghahramani, Mojtaba Farjam
    European Journal of Medical Research.2025;[Epub]     CrossRef
  • The Impact of the Mediterranean Diet, Physical Activity, and Nutrition Education on Pediatric Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD): A Review
    Melvin Bernardino, Claudio Tiribelli, Natalia Rosso
    Nutrients.2025; 18(1): 28.     CrossRef
  • Machine learning-based model for predicting metabolic dysfunction-associated steatotic liver disease using non-invasive parameters in young adults
    Kyungchul Song, Yu-Jin Kwon, Eunju Lee, Young Hoon Youn, Su Jung Baik, Hye Sun Lee, Hyun Wook Chae
    Frontiers in Endocrinology.2025;[Epub]     CrossRef
  • Soft drink consumption and liver fibrosis in type 2 diabetes
    Arianna Ferro, Martina Bollati, Gian Paolo Caviglia, Angelo Armandi, Stefania Bellini, Selene Limoncelli, Giulio Mengozzi, Federica Barutta, Fabio Broglio, Guglielmo Beccuti, Elisabetta Bugianesi, Marilena Durazzo, Gabriella Gruden
    Frontiers in Nutrition.2025;[Epub]     CrossRef
  • Artificial intelligence applications for managing metabolic dysfunction-associated steatotic liver disease: Current status and future prospects
    Jian-Jun Lou, Jing Zeng
    World Journal of Gastroenterology.2025;[Epub]     CrossRef
  • Dual target, dual benefit: real-world effects of SGLT2 inhibitors and GLP-1 receptor agonists on the FIB-4 score in people with type 2 diabetes mellitus
    Virginia Markoutsaki, Georgios Dimakopoulos, Emmanouil Sinakos, Kalliopi Kotsa, Theocharis Koufakis
    Hormones.2025;[Epub]     CrossRef
  • Metabolic dysfunction-associated steatotic liver disease and risk of heart failure: a nationwide cohort study
    Chan Kyeol Kim, Sangyong Jo, Kyupin Ha, Bongjo Kim, Hyeon Ji Kim, Sang Yi Moon, Byoung-Gwon Kim, Kyungil Park, Jong Sung Park, Young Rak Cho, Tae-Ho Park, Kyunghee Lim, Minkook Son
    Heart.2025; : heartjnl-2025-327102.     CrossRef
  • Association between vitamin D and metabolic-associated steatotic liver disease in type 2 diabetes mellitus patients: a systematic review and meta-analysis
    Bruno Basil, Winifred Adiri, Ejike Lawrence Ugwu, Ngozi Ijeoma Okoro
    Diabetology & Metabolic Syndrome.2025;[Epub]     CrossRef
  • Association between atherosclerosis-related indicators and fatty liver: a population-based observational study
    Xiaoping Liu, Ping Yuan, Ying Huang
    European Journal of Medical Research.2025;[Epub]     CrossRef
  • Associations Between Systemic Inflammatory Markers, Metabolic Dysfunction, and Liver Fibrosis Scores in Patients with MASLD
    Ragaey Ahmad Eid, Ahmed Moheyeldien Hamed, Sara O. Elgendy, Khalid M. Orayj, Ahmed R. N. Ibrahim, Ahmed M. Abdel Hamied, Engy A. Wahsh, Maha Youssif, Hoda Rabea, Yasmin M. Madney, Dina Attia, Shaymaa Nafady
    Metabolites.2025; 16(1): 25.     CrossRef
  • Phase III, multicenter, randomized, double-blind, placebo-controlled study of norursodeoxycholic acid in metabolic dysfunction-associated steatotic liver disease patients
    Veerendra Kumar Panuganti, Chandrasekhar Varma Alluri, Javeed Mohammad, Mamatha Reddy Dundigalla, Pavan Kumar Madala, Sanyasirao KSSVV, Althaf Shaik
    World Journal of Hepatology.2025;[Epub]     CrossRef
  • Interplay between intestinal permeability and metabolic dysfunction-associated steatotic liver disease: Could there be a role for extra virgin olive oil consumption?
    Lydia Giannitrapani, Marinella Ferraro, Aurelio Seidita, Anna Licata, Maurizio Soresi
    World Journal of Hepatology.2025;[Epub]     CrossRef
  • Does Continuous Positive Airway Pressure Improve Liver Outcomes in MASLD with Obstructive Sleep Apnea? A Systematic Review
    Theja V. Channapragada, Clinton R. Brenner, Keven Guruswamy, Rewanth Katamreddy, Alwyn T. Pandian, Vyshnavi Pendala, Jaydon J. Sam, Jonathan G. Stine, Michael J. Brenner, Vinciya Pandian
    Journal of Clinical Medicine.2025; 15(1): 225.     CrossRef
  • Independent and Combined Effects of Resistance Training and Whey Protein on Skeletal Muscle Mass and Function in Individuals with MASLD Under Caloric Restriction
    Chae-Been Kim, Jinwoo Sung, Dohyun Ahn, Eun-Ah Jo, Kyung-Wan Baek, Hae-Ri Heo, Ju-Hwan Oh, Fengrui Zhang, Hyoung-Su Park, Hong-Soo Kim, Jung-Jun Park
    Nutrients.2025; 18(1): 83.     CrossRef
  • SGLT2 Inhibitors as Systemic Metabolic Modulators: Linking Glucose Excretion to Liver Function Restoration
    Seung Wan Noh, Han Sol Ryu, Yong-Ho Kim, Byung-Chul Oh
    Endocrinology and Metabolism.2025; 40(6): 851.     CrossRef
  • Impact of liraglutide and dapagliflozin on steatosis, fibrosis, aminotransferases, and lipid profile in patients with metabolic dysfunction-associated steatotic liver disease and type 2 diabetes mellitus: results of a 6-month randomized study
    V.V. Cherniavskyi, A.I. Akimov, V.V. Tishchenko, L.M. Parunian
    GASTROENTEROLOGY.2025; 59(4): 269.     CrossRef
  • Circulating histones as potential biomarkers of MASLD-MASH-HCC progression
    Desislava K. Tsoneva, Diana Buzova, Salvatore Daniele Bianco, Maria Rita Braghini, Giulia Andolina, Antonio Liguori, Francesca D’ Ambrosio, Andrea Urbani, Antonio Gasbarrini, Maurizio Pompili, Anna Alisi, Jan Cerveny, Tommaso Mazza, Manlio Vinciguerra, Lu
    Epigenomics.2025; 17(18): 1435.     CrossRef
  • Modelos Animais de MASLD/NAFLD: uma revisão narrativa do estado atual e perspectivas futuras
    Gabriel dos Santos, Fabio de Castro Machado, Ana Beatriz Serrato Carmo, Alvaro Ivanski Sabedotti, Laura Moscardi Milléo, Lorenzo Cultz, Mateus Baptista Pizyblski, Leonardo Henrique de Figueiredo Lima, Mário Cláudio Soares Sturzeneker
    Cuadernos de Educación y Desarrollo.2025; 17(12): e10446.     CrossRef
  • THE EFFECT OF S-ADENOSYLMETHIONINE ON LIPID PROFILE PARAMETERS IN PATIENTS WITH MULTIPLE MYELOMA AND CONCOMITANT METABOLIC DYSFUNCTION–ASSOCIATED STEATOTIC LIVER DISEASE DURING CHEMOTHERAPY
    Y. Stadnik, G. Maslova
    Актуальні проблеми сучасної медицини: Вісник Української медичної стоматологічної академії.2025; 25(4): 76.     CrossRef
  • Serum Biomarkers for Hepatocellular Carcinoma: A Comparative Review of Traditional and Emerging Markers
    Min Kyung Park
    Journal of Digestive Cancer Research.2025; 13(3): 242.     CrossRef
  • Cardiovascular–kidney–metabolic syndrome and the risk of liver fibrosis progression and liver-related events in MASLD
    Xiao-Dong Zhou, Qin-Fen Chen, Qiong-Yue Fan, Seung Up Kim, Terry Cheuk-Fung Yip, Salvatore Petta, Atsushi Nakajima, Emmanuel Tsochatzis, Jérôme Boursier, Elisabetta Bugianesi, Hannes Hagström, Wah-Kheong Chan, Manuel Romero-Gomez, José Luis Calleja, Victo
    Hepatology.2025;[Epub]     CrossRef
  • Risk Factors for Liver Fibrosis in Patients with Type 2 Diabetes Mellitus and Metabolic Dysfunction–Associated Steatotic Liver Disease in Brazzaville
    Farel Elilie Mawa Ongoth, Rudel Godrèche Kondo, Philestine Clausina Mikolélé Ahoui Apendi, Nestor Ghislain Andzouana Mbamognoua, Raïssa Laure Mayanda Ohouana, Aymande Okoumou-Moko, Ornella Marline Yvonne Dinghat, Joël Rudy Ekoundzola, Sévérin Nkoua Eloi,
    Open Journal of Endocrine and Metabolic Diseases.2025; 15(08): 142.     CrossRef
  • Kidney function mediates the association of per- and poly-fluoroalkyl substances (PFAS) and heavy metals with hepatic fibrosis risk
    Zhengqi Wei, Jincheng Liu, Na Wang, Keke Wei
    Environmental Research.2024; 263: 120092.     CrossRef
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    Fahad Lakhdhir, Agha Syed Muhammad, Ahmed Nasir Qureshi, Imran A Shaikh, Imran Joher, Jawaria Majeed, Javaria Khan
    Cureus.2024;[Epub]     CrossRef
  • Leukocyte telomere shortening in metabolic dysfunction-associated steatotic liver disease and all-cause/cause-specific mortality
    Donghee Kim, Pojsakorn Danpanichkul, Karn Wijarnpreecha, George Cholankeril, Aijaz Ahmed
    Clinical and Molecular Hepatology.2024; 30(4): 982.     CrossRef
  • Understanding the epidemiology of metabolic dysfunction-associated steatotic liver disease is essential for its management: need for attention to accurate diagnostic coding and classification
    Han Ah Lee
    The Korean Journal of Internal Medicine.2024; 39(6): 869.     CrossRef
  • AI in Hepatology: Revolutionizing the Diagnosis and Management of Liver Disease
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    Journal of Clinical Medicine.2024; 13(24): 7833.     CrossRef
  • 65,535 View
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Letter to the Editor

Steatotic liver disease

Equivalent prevalence and progression of chronic kidney disease in non-alcoholic fatty liver disease and metabolic dysfunction-associated steatotic liver disease
Hiroyuki Suzuki, Tsubasa Tsutsumi, Machiko Kawaguchi, Keisuke Amano, Takumi Kawaguchi
Clin Mol Hepatol 2024;30(4):962-964.
Published online May 20, 2024
DOI: https://doi.org/10.3350/cmh.2024.0264

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  • Metabolic dysfunction‐associated steatotic liver disease (SLD) and alcohol‐associated liver disease, but not SLD without metabolic dysfunction, are independently associated with new onset of chronic kidney disease during a 10‐year follow‐up period
    Kazuma Mori, Marenao Tanaka, Tatsuya Sato, Yukinori Akiyama, Keisuke Endo, Toshifumi Ogawa, Toru Suzuki, Hiroki Aida, Wataru Kawaharata, Kei Nakata, Itaru Hosaka, Araya Umetsu, Nagisa Hanawa, Masato Furuhashi
    Hepatology Research.2025; 55(1): 34.     CrossRef
  • Metabolic dysfunction-associated steatotic liver disease and risk of four intrahepatic and extrahepatic diseases
    Yiyuan Xiao, Sihua Xu, Wenyan Hu, Jiapeng Huang, Deke Jiang, Rong Na, Zhaoqing Yin, Jingjing Zhang, Haitao Chen
    Annals of Hepatology.2025; 30(1): 101750.     CrossRef
  • Chronic Kidney Disease Risk Associated With Metabolic Dysfunction‐Associated Steatotic Liver Disease: A Nationwide Cohort Study in Korea
    Dong Wook Kim, Minkook Son, Hye Jung Lee, Chi Hyeon Choi, Yeo Wool Kang, Sang Yi Moon, Myeongseok Koh, Jong Yoon Lee, Yang Hyun Baek, Won Suk An
    Hepatology Research.2025; 55(9): 1239.     CrossRef
  • Changes in the epidemiological trends of primary liver cancer in the Asia–Pacific region
    Pojsakorn Danpanichkul, Kanokphong Suparan, Banthoon Sukphutanan, Chuthathip Kaeosri, Primrose Tothanarungroj, Supapitch Sirimangklanurak, Markos Kalligeros, Natchaya Polpichai, Yanfang Pang, Karn Wijarnpreecha, Pimsiri Sripongpun, Naichaya Chamroonkul, M
    Scientific Reports.2024;[Epub]     CrossRef
  • Pemafibrate Reduced Liver Stiffness in Patients with Metabolic Dysfunction-associated Steatotic Liver Disease Complicated with Hyperlipidemia and Liver Fibrosis with a Fibrosis-4 Index Above 1.3
    Tatsuki Ichikawa, Mio Yamashima, Shinobu Yamamichi, Makiko Koike, Yusuke Nakano, Hiroyuki Yajima, Osamu Miyazaki, Tomonari Ikeda, Takuma Okamura, Naohiro Komatsu, Sayuri Sugio, Miruki Yoshino, Hisamitsu Miyaaki
    Internal Medicine.2024;[Epub]     CrossRef
  • 6,114 View
  • 120 Download
  • 5 Web of Science
  • Crossref

Original Article

Steatotic liver disease

Global prevalence of metabolic dysfunction-associated fatty liver disease-related hepatocellular carcinoma: A systematic review and meta-analysis
Harry Crane, Guy D. Eslick, Cameron Gofton, Anjiya Shaikh, George Cholankeril, Mark Cheah, Jian-Hong Zhong, Gianluca Svegliati-Baroni, Alessandro Vitale, Beom Kyung Kim, Sang Hoon Ahn, Mi Na Kim, Simone I Strasser, Jacob George
Clin Mol Hepatol 2024;30(3):436-448.
Published online April 16, 2024
DOI: https://doi.org/10.3350/cmh.2024.0109
Background/Aims
The global proportion of hepatocellular carcinoma (HCC) attributable to metabolic dysfunction-associated fatty liver disease (MAFLD) is unclear. The MAFLD diagnostic criteria allows objective diagnosis in the presence of steatosis plus defined markers of metabolic dysfunction, irrespective of concurrent liver disease. We aimed to determine the total global prevalence of MAFLD in HCC cohorts (total-MAFLD), including the proportion with MAFLD as their sole liver disease (single-MAFLD), and the proportion of those with concurrent liver disease where MAFLD was a contributary factor (mixed-MAFLD).
Methods
This systematic review and meta-analysis included studies systematically ascertaining MAFLD in HCC cohorts, defined using international expert panel criteria including ethnicity-specific BMI cut-offs. A comparison of clinical and tumour characteristics was performed between single-MAFLD, mixed-MAFLD, and non-MAFLD HCC.
Results
22 studies (56,565 individuals with HCC) were included. Total and single-MAFLD HCC prevalence was 48.7% (95% confidence interval [CI] 34.5–63.0%) and 12.4% (95% CI 8.3–17.3%), respectively. In HCC due to chronic hepatitis B, C, and alcohol-related liver disease, mixed-MAFLD prevalence was 40.0% (95% CI 30.2–50.3%), 54.1% (95% CI 40.4–67.6%) and 64.3% (95% CI 52.7–75.0%), respectively. Mixed-MAFLD HCC had significantly higher likelihood of cirrhosis and lower likelihood of metastatic spread compared to single-MAFLD HCC, and a higher platelet count and lower likelihood of macrovascular invasion compared to non-MAFLD HCC.
Conclusions
MAFLD is common as a sole aetiology, but more so as a co-factor in mixed-aetiology HCC, supporting the use of positive diagnostic criteria.

Citations

Citations to this article as recorded by  Crossref logo
  • Astragaloside IV alleviates metabolic associated fatty liver disease by regulating ferroptosis via the SLC7A11/GPX4 pathway
    Sitong CHEN, Hanying XU, Zipei ZHANG, Xiaonan LI, Xiaolei TANG, Dashi YING
    Chinese Journal of Analytical Chemistry.2026; 54(2): 100625.     CrossRef
  • Even Lower Alcohol Intake Might Be Harmful for East Asian Males With MASLD Spectrum
    Byungyoon Yun, Juyeon Oh, Heejoo Park, Jian Lee, Beom Kyung Kim, Jin-Ha Yoon
    Clinical Gastroenterology and Hepatology.2026; 24(6): 1644.     CrossRef
  • Obstructive sleep apnea is associated with greater MASH and significant fibrosis severity in patients with obesity: A prospective clinicopathological study
    Jia Feng, Wenhui Chen, Zunhao Zhang, Fuqing Zhou, Yang Liu, Zhirui Qiu, Yan Liu, Zhiyong Dong, Cunchuan Wang, Hao Wang, Yi Ma
    Diabetes, Obesity and Metabolism.2026; 28(3): 1972.     CrossRef
  • Rising burden of MASLD and CKM syndrome in Asia: A decade of trends and future projections
    Tianqi Duo, Yun Wen, Yu Bian, Yizheng Wang, Xiaofang Zhang, Jin Ju, Yanjie Lu, Zhiguo Wang, Jinghao Wang, Baofeng Yang
    Metabolism.2026; 178: 156549.     CrossRef
  • Integrating body composition analysis and machine learning for non-invasive identification of metabolic dysfunction-associated fatty liver disease: a large-scale health examination-based study
    Yaxuan He, Yu Cao, Zekai Chen, Rong Xiang, Fang Wang
    Scientific Reports.2026;[Epub]     CrossRef
  • Comparison of patients with HCC with and without MASLD after surgical resection
    Chia-Jung Ho, Hao-Jan Lei, Chun-Ting Ho, Gar-Yang Chau, Shu-Cheng Chou, Elise Chia-Hui Tan, Pei-Chang Lee, Yi-Hsiang Huang, Ying-Ying Yang, Teh-Ia Huo, Ming-Chih Hou, Jaw-Ching Wu, Chien-Wei Su
    JHEP Reports.2026; 8(4): 101768.     CrossRef
  • Diagnosis and management of metabolic dysfunction-associated steatohepatitis in patients with chronic hepatitis B infection
    Talal K Bhatti, Joseph K Lim
    World Journal of Gastroenterology.2026;[Epub]     CrossRef
  • Comparison of the efficacy of transarterial chemoembolization combined with radiofrequency ablation or sintilimab and bevacizumab for unresectable hepatocellular carcinoma
    Tingting Li, Hongyi Zhao, Chengbin Dong, Yang Song, Miaomiao Li
    BMC Gastroenterology.2026;[Epub]     CrossRef
  • Integrative Multiomics Analysis Reveals the Ameliorative Effects of Astragalus membranaceus Extract on Metabolic Dysfunction-Associated Steatotic Liver Disease
    Jiayi An, Yi Li, Zunhan Zhang, Yaru Chang, Guanxiu Xiao
    Molecules.2026; 31(7): 1120.     CrossRef
  • Noncanonical function of epigenetic reader YTHDF1 inhibits MASLD progression by maintaining peroxisomes and mitochondrial homeostasis
    Chenyang Mu, Jian Tan, Yuefan Wang, Haozan Yin, Zhihui Dai, Zenghan Wang, Dongyang Ding, Zhichao Zhang, Sijie Wang, Hui Liu, Fu Yang
    Experimental & Molecular Medicine.2026; 58(4): 1172.     CrossRef
  • ​​Integrating machine learning and spatial transcriptomics uncovers shared immunomodulatory deubiquitinases in MAFLD and HCC
    Yu-xi Han, Hongze Li, Wendi Xia, Junyi Ma, Jiaqi Zhang, Yiling Li
    Human Genetics.2026;[Epub]     CrossRef
  • Role of the NF-κB signaling pathway in vascular endothelial cell injury associated with metabolic dysfunction-associated steatotic liver disease under hypoxia
    Jingxuan Zhang, Chenguang Zhang, Chao Yang, Yongjun Miao, Xiaomeng Wei, Zijian Zhang, Zihan Shen, Guodan Bao
    Biochemical and Biophysical Research Communications.2026; 817: 153710.     CrossRef
  • Metabolic Dysfunction‐Associated Steatotic Liver Disease and Obesity: Pathogenesis, Diagnostics, Risk Stratification, and Therapeutic Approach
    Beom Kyung Kim
    The Kaohsiung Journal of Medical Sciences.2026;[Epub]     CrossRef
  • Association Between Uric‐Acid‐to‐HDL Ratio and Hepatic Steatosis Diagnosed by Liver Ultrasound Transient Elastography
    Lili Chu, Meng Wu, Bo Zhang, Jinger Lu, Ying Chen, Zhiwen Luo
    International Journal of Clinical Practice.2026;[Epub]     CrossRef
  • Risk factors for non-alcoholic fatty liver disease in pregnant women as a basis for in-depth examination and prevention of obstetric complications
    Elena V. Mozgovaya, Marina A. Kryshnia
    Journal of obstetrics and women's diseases.2026; 75(2): 42.     CrossRef
  • Reply to “Enhancing Capsule on Liver CT: Implications for Steatotic Liver Disease”
    Se Jin Choi, Dong Hwan Kim, Jae Ho Byun
    American Journal of Roentgenology.2026;[Epub]     CrossRef
  • Valerenic acid attenuates chronic stress-exacerbated metabolic dysfunction-associated steatotic liver disease via the estrogen receptor α-GDF15 axis
    Xingli Wu, Yuzi Jiang, Junmin Wang, Simin Gu, Yanping Wang, Ning Li, Chunmei Qian, Hongming Nie, Yiyuan Zheng, Yong Li
    European Journal of Pharmacology.2026; 1030: 179106.     CrossRef
  • Traditional Chinese Medicines for Metabolic Dysfunction‐Associated Steatotic Liver Disease: A Mixed‐Method Systematic Review
    Zhipeng Wei, Liping Guo, Guohua Zhang, Yicheng Qian, Zhou Lan, Kehu Yang
    Journal of Evidence-Based Medicine.2026;[Epub]     CrossRef
  • Association of the Number of Concurrent Metabolic Syndrome Risk Factors with Textbook Outcomes Following Liver Resection for Patients with Hepatocellular Carcinoma: A Multicenter Study
    Zhan-Cheng Qiu, Jun-Long Dai, Yu Zhang, Fei Xie, Yu Yu, Shu-Sheng Leng, Tian-Fu Wen, Chuan Li
    Annals of Surgical Oncology.2025; 32(1): 399.     CrossRef
  • Deciphering the roles of neddylation modification in hepatocellular carcinoma: Molecular mechanisms and targeted therapeutics
    Wenxin Wu, Xuanyi Wang, Ruijie Ma, Shuhong Huang, Hongguang Li, Xinxing Lyu
    Genes & Diseases.2025; 12(4): 101483.     CrossRef
  • Alterations of Krüppel-like Factor Signaling and Potential Targeted Therapy for Hepatocellular Carcinoma
    Rongfei Fang, Chunxiu Sha, Qun Xie, Dengfu Yao, Min Yao
    Anti-Cancer Agents in Medicinal Chemistry.2025; 25(2): 75.     CrossRef
  • Associations of MAFLD subtypes and air pollutants with multi-system morbidity and all-cause mortality: A prospective cohort study
    Jingyi Zhang, Shanshan Ran, Shengtao Wei, Fei Tian, Lan Chen, Zijun Yang, Ge Chen, Hualiang Lin
    Ecotoxicology and Environmental Safety.2025; 291: 117893.     CrossRef
  • Global burden and international disparities in NASH-associated liver Cancer: mortality trends (1990–2021) and future projections to 2045
    Qilong Nie, Yongwen Jiang, Mingyang Li, Qiuyan Liang, Xiaoai Mo, Tengyu Qiu, Qunfang Jiang, Kaizhou Huang, Youqing Xie, Ying Chen, Xiaojun Ma, Jianhong Li, Kaiping Jiang
    Frontiers in Public Health.2025;[Epub]     CrossRef
  • Exploring emerging frontiers in hepatology: iLIVER's continuing journey
    Ming-Da Wang, Xin-Fei Xu, Lei Cai, Tian Yang
    iLIVER.2025; 4(1): 100148.     CrossRef
  • A review of image guidance and localization methods for liver puncture robots
    Yongde Zhang, Jiabin Yang, Xuequan Huang, Chuang He
    Journal of Robotic Surgery.2025;[Epub]     CrossRef
  • Comparative Hepatic Outcomes of SGLT2i or DPP4i Compared to GLP‐1RA in CHB and T2DM Patients
    Byungyoon Yun, Juyeon Oh, Heejoo Park, Jian Lee, Beom Kyung Kim, Jin‐Ha Yoon
    Liver International.2025;[Epub]     CrossRef
  • Cardiovascular implications of metabolic dysfunction-associated fatty liver disease and type 2 diabetes mellitus: A meta-analysis
    Sahana Shetty, Renuka Suvarna, Vanessa Ambrose Fistus, Shivam Modi, Joseph M Pappachan
    World Journal of Hepatology.2025;[Epub]     CrossRef
  • Characterisation of non-cirrhotic MAFLD-related hepatocellular carcinoma: a retrospective cohort study
    Shadi Zerehpooshnesfchi, Fatema Safri, Ziyan Pan, Romario Nguyen, Lawrence Yuen, Vincent Lam, Christopher Nahm, Tony Pang, Golo Ahlenstiel, Jacob George, Mohammed Eslam, Liang Qiao
    Therapeutic Advances in Chronic Disease.2025;[Epub]     CrossRef
  • Case Report: Amelioration of severe metabolic dysfunction-associated steatohepatitis after switching from conventional GLP-1RAs to tirzepatide
    Yuki Oe, Takashi Omori, Eriko Aimono, Shin Furukawa, Hirohiko Kitakawa, Masatoshi Tateno, Kiyoshi Sakai, Kyu Yong Cho
    Frontiers in Endocrinology.2025;[Epub]     CrossRef
  • Trends and visualization analysis of research on MASLD-Related hepatocellular carcinoma: a bibliometric analysis
    Hongkun Yin, Xusheng Zhang, Qi Wang
    Discover Oncology.2025;[Epub]     CrossRef
  • Overweight and Helicobacter pylori infection: a correlation in metabolic dysfunction-associated fatty liver disease
    Xu Chen, Jiayue Fu, Kejia Jin, Zixuan Yang, Yidan Qian, Kehan Mei, Yihan Wang, Jialei Min, Yilin Du, Zaisheng Zhu, Shengcun Li
    Frontiers in Cellular and Infection Microbiology.2025;[Epub]     CrossRef
  • Hemostatic alterations in metabolic dysfunction-associated steatotic liver disease (MASLD) and their link to venous thromboembolism (VTE)
    David E. González-Mendoza, Francisco Fernández-Nogueira, Misael Uribe, Norberto C. Chávez-Tapia, Natalia Nuño-Lámbarri
    Thrombosis Research.2025; 253: 109395.     CrossRef
  • Rewriting the MASLD‐associated hepatocellular carcinoma script: Targeting epigenetics and metabolism
    Chiara Aiello, Eric Felli, Teresa Musarra, Lorenzo Nevi, Annamaria Altomare, Jordi Gracia‐Sancho, Andrea Baiocchini, Simone Carotti
    International Journal of Cancer.2025; 157(10): 1991.     CrossRef
  • Role of mac-2 binding protein glycosylation isomer in predicting fibrosis in patients with metabolic dysfunction-associated steatotic liver disease
    Thuy Thi Thu Pham, Dat Tan Ho, Chanh Pham, Hoan Phan, Bieu Phu, Toan Nguyen, Dang Nguyen, Hai Thanh Phan, Khue Minh Nguyen
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  • The triadic relationship between nonalcoholic fatty liver disease, type 2 diabetes, and cardiovascular disease: From molecular mechanisms to clinical management
    Yuxi Jin, Mohammed Alissa, Ahmed Ezzat Ahmed, Amin A. Al-Doaiss, Naif Asiri, Yasser Assiri, Shahid Ullah Khan, Munir Ullah Khan, Samuel Joseph
    Current Problems in Cardiology.2025; 50(11): 103170.     CrossRef
  • Exploring the Link Between Irritable Bowel Syndrome and Chronic Diseases: A Narrative Overview
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    Academic Medicine & Surgery.2025;[Epub]     CrossRef
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    Junzhao Ye, Rui Song, Xiaorong Gong, Xin Li, Congxiang Shao, Bihui Zhong
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  • Lipid metabolism in cancer cells: Its role in hepatocellular carcinoma progression and therapeutic resistance
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  • Hepatocellular carcinoma: modern aspects of interdisciplinary management. Part 1. Epidemiology, risk factors, diagnosis
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    GASTROENTEROLOGY.2025; 59(3): 206.     CrossRef
  • Protective effect and mechanisms of puerarin in metabolic dysfunction-associated steatotic liver disease: A systematic review and meta-analysis of animal studies
    Xiang-yun Zou, Yu-cheng Yang, Xue-han Liu, Wen-ying Qi, Xiao-bin Zao, Xiao-ke Li, Yong’an Ye
    Pharmacological Research.2025; 222: 108024.     CrossRef
  • A comprehensive bibliometric and visual analysis of tumor-associated macrophages in hepatocellular carcinoma
    GuanBo Zhang, Gang Li, JinSong Li, Jie Zhang, Zhi Yang, Lin Yang, ShiJie Jiang, ShiFan Zhu, JiaXing Wang
    Discover Oncology.2025;[Epub]     CrossRef
  • Targeting Ferroptosis: New Insights and Therapeutic Advances in MAFLD Complicating T2DM
    Fang Yao, Gaochao Wang, Fan Ning, Yanbo Shi
    Frontiers in Bioscience-Landmark.2025;[Epub]     CrossRef
  • Lean Metabolic Dysfunction‐Associated Steatotic Liver Disease: A Wolf in Sheep's Clothing
    Xixi Fang, Chenhao Xu, Jun Lu, Runzhou Zhuang, Xiao Xu, Xuyong Wei
    Cell Biochemistry and Function.2025;[Epub]     CrossRef
  • Glucagon‐Like Peptide‐1 Receptor Agonists and Hepatocellular Carcinoma Prevention: A Meta‐Analysis and Clinical Decision Framework
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    Cancer Medicine.2025;[Epub]     CrossRef
  • Mechanistic roles and intervention strategies involving gut microbiota, amino acid metabolism, and the tumor immune microenvironment in MAFLD-HCC progression
    Ziwei Guo, Ziang Yao, Xiaohan Chen, Dongjie Wu, Yaqi Ouyang, Yaocun Shen, Yi Wang, Houyan Zhang, Yanping Lu, Wenliang Lv
    Clinical and Experimental Medicine.2025;[Epub]     CrossRef
  • Splanchnic inflammatory syndrome and the not-so-silent risk of cancer
    Richard C Semelka MD, Miguel Ramalho MD
    Gastroenterology & Hepatology: Open access.2024; 15(3): 63.     CrossRef
  • Metabolic dysfunction-associated fatty liver disease is a ubiquitous latent cofactor in viral- and alcoholic-related hepatocellular carcinoma: Editorial on “Global prevalence of metabolic dysfunction-associated fatty liver disease-related hepatocellular c
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    iLIVER.2024; 3(3): 100113.     CrossRef
  • Impact of occult hepatitis B virus infection and high-fat diet on hepatocellular carcinoma development
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    Hepatoma Research.2024;[Epub]     CrossRef
  • Metabolic (dysfunction)-associated fatty liver disease metrics and contributions to liver research
    Maito Suoh, Saeed Esmaili, Mohammed Eslam, Jacob George
    Hepatology International.2024; 18(6): 1740.     CrossRef
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  • 51 Web of Science
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Letter to the Editor

Steatotic liver disease

Changing from NAFLD to MASLD: Similar prognosis of patients with HCC under atezolizumab/bevacizumab treatment between NAFLD and MASLD
Hiroyuki Suzuki, Shigeo Shimose, Hideki Iwamoto, Takashi Niizeki, Takumi Kawaguchi
Clin Mol Hepatol 2024;30(2):263-265.
Published online January 18, 2024
DOI: https://doi.org/10.3350/cmh.2023.0557

Citations

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  • Metabolic dysfunction-associated steatotic liver disease and risk of four intrahepatic and extrahepatic diseases
    Yiyuan Xiao, Sihua Xu, Wenyan Hu, Jiapeng Huang, Deke Jiang, Rong Na, Zhaoqing Yin, Jingjing Zhang, Haitao Chen
    Annals of Hepatology.2025; 30(1): 101750.     CrossRef
  • Role of noninvasive tests in the prognostication of metabolic dysfunction-associated steatotic liver disease
    Yue Wang, Sherlot Juan Song, Yichong Jiang, Jimmy Che-To Lai, Grace Lai-Hung Wong, Vincent Wai-Sun Wong, Terry Cheuk-Fung Yip
    Clinical and Molecular Hepatology.2025; 31(Suppl): S51.     CrossRef
  • Pathogenic Mechanisms of Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)-Associated Hepatocellular Carcinoma
    Toru Nakamura, Atsutaka Masuda, Dan Nakano, Keisuke Amano, Tomoya Sano, Masahito Nakano, Takumi Kawaguchi
    Cells.2025; 14(6): 428.     CrossRef
  • Efficacy of measuring natural killer-activating receptor ligands to predict the pathogenesis of metabolic dysfunction-associated steatotic liver disease
    Jun Arai, Akinori Okumura, Satoshi Kimoto, Kazumasa Sakamoto, Tomoya Kitada, Rena Kitano, Tadahisa Inoue, Sayaka Nishimura, Noriko Inden, Yukiko Muraki, Naoya Kato, Kiyoaki Ito
    Hepatology International.2025; 19(4): 836.     CrossRef
  • C-C motif chemokines ligand 7 contributes to metabolic dysfunction-associated steatotic liver disease by enabling redox-sensitive induction of hypermethylated in cancer 1
    Xinyue Sun, Jinge Wu, Huiqian Lv, Ben Wang, Xuelian Chen, Wenjing Ren, Xiulian Miao, Yan Guo, Xiaocen Kong, Huihui Xu, Zeqing Bao, Yong Xu, Zilong Li
    Metabolism.2025; 168: 156242.     CrossRef
  • Association between nonalcholic fatty liver disease and pancreatic cancer: Epidemiology, mechanisms, and antidiabetic medication
    Takahiko Sakaue, Hiroya Terabe, Hidetoshi Takedatsu, Takumi Kawaguchi
    Hepatology Research.2024; 54(8): 729.     CrossRef
  • Usefulness of health checkup‐based indices in identifying metabolic dysfunction‐associated steatotic liver disease
    Takao Miwa, Satoko Tajirika, Nanako Imamura, Miho Adachi, Ryo Horita, Tatsunori Hanai, Cheng Han Ng, Mohammad Shadab Siddiqui, Taku Fukao, Masahito Shimizu, Mayumi Yamamoto
    JGH Open.2024;[Epub]     CrossRef
  • Disparities in metabolic dysfunction-associated steatotic liver disease and cardiometabolic conditions in low and lower middle-income countries: a systematic analysis from the global burden of disease study 2019
    Pojsakorn Danpanichkul, Kanokphong Suparan, Priyata Dutta, Chuthathip Kaeosri, Banthoon Sukphutanan, Yanfang Pang, Narathorn Kulthamrongsri, Methasit Jaisa-aad, Cheng Han Ng, Margaret Teng, Masahito Nakano, Asahiro Morishita, Naim Alkhouri, Ju Dong Yang,
    Metabolism.2024; 158: 155958.     CrossRef
  • Changing from NAFLD to MASLD: Prevalence and progression of ASCVD risk are similar between NAFLD and MASLD in Asia
    Hiroyuki Suzuki, Tsubasa Tsutsumi, Machiko Kawaguchi, Keisuke Amano, Takumi Kawaguchi
    Clinical and Molecular Hepatology.2024; 30(3): 577.     CrossRef
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    JGH Open.2024;[Epub]     CrossRef
  • Equivalent prevalence and progression of chronic kidney disease in non-alcoholic fatty liver disease and metabolic dysfunction-associated steatotic liver disease
    Hiroyuki Suzuki, Tsubasa Tsutsumi, Machiko Kawaguchi, Keisuke Amano, Takumi Kawaguchi
    Clinical and Molecular Hepatology.2024; 30(4): 962.     CrossRef
  • 7,278 View
  • 164 Download
  • 12 Web of Science
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Correspondence

Steatotic liver disease

Correspondence on Letter regarding “Waiting for the changes after the adoption of steatotic liver disease”
Eileen L. Yoon, Dae Won Jun
Clin Mol Hepatol 2024;30(1):126-128.
Published online November 28, 2023
DOI: https://doi.org/10.3350/cmh.2023.0500
  • 7,904 View
  • 60 Download

Special Review

Steatotic liver disease

Waiting for the changes after the adoption of steatotic liver disease
Eileen L. Yoon, Dae Won Jun
Clin Mol Hepatol 2023;29(4):844-850.
Published online September 6, 2023
DOI: https://doi.org/10.3350/cmh.2023.0291
Steatotic liver disease was suggested as an overarching term encompassing various etiologies of hepatic steatosis. Experts from multinational liver societies went through the Delphi process, including four rounds of surveys, and consented to adopt a new nomenclature and definition instead of the conventional nonalcoholic fatty liver disease (NAFLD). This was to improve the understanding of the patients and primary care physicians, with an explanation of the pathophysiology in the name of the disease. Also, it could minimize the stigmatization of patients by using the histological neutral term “steatosis” instead of “fatty”. Herein, we will discuss the changes and continuity between the two nomenclatures, metabolic dysfunction-associated steatotic liver disease (MASLD) and NAFLD, as well as the challenges to MASLD which need to be addressed in future.

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  • Association between dietary amino acid intake and the risk of metabolic dysfunction-associated steatotic liver disease
    Ruoqi Zhou, Xinrong Zhang, Xinxin Liu, Rui Huang, Yuwei Wang, Dajing Xia, Xue Li, Yihua Wu, Yu Shi
    Journal of Advanced Research.2026; 80: 893.     CrossRef
  • Aspirin and hepatocellular carcinoma risk in metabolic dysfunction-associated steatotic liver disease: nationwide cohort study with genetic risk analysis
    Juhee Ahn, Moon Haeng Hur, Hyunjae Shin, Min Kyung Park, Sungho Won, Jeayeon Park, Yunmi Ko, Youngsu Park, Yun Bin Lee, Eun Ju Cho, Jeong-Hoon Lee, Su Jong Yu, Jung-Hwan Yoon, Yoon Jun Kim
    Clinical and Molecular Hepatology.2026; 32(1): 339.     CrossRef
  • Association between diabetes and in‐hospital outcomes in patients with metabolic dysfunction‐associated steatotic liver disease hospitalized for cardiovascular disease: A nationwide database study
    Soichi Komaki, Michikazu Nakai, Yunosuke Matsuura, Kinuko Yamamoto, Hiroki Tanaka, Yuri Komaki, Masashi Yamaguchi, Kohei Moribayashi, Takeshi Ideguchi, Hiroshi Kawakami, Toshihiro Tsuruda, Koichi Kaikita
    Diabetic Medicine.2026;[Epub]     CrossRef
  • Targeted Food-Grade Delivery Systems for Liver Injury Intervention: A Comprehensive Review of Nanocarrier Strategies
    Jixian Zhang, Jieyu Wang, Guoyan Liu, Xin Xu, Chaoting Wen
    Advanced Functional Foods.2026; 2(2): 98.     CrossRef
  • Reply to: “Is liver fibrosis more advanced in MetALD than in MASLD?”
    Joo Hyun Oh, Dae Won Jun
    Journal of Hepatology.2025; 82(1): e58.     CrossRef
  • Statin use and liver-related prognosis among patients with MASLD
    Byungyoon Yun, Heejoo Park, Jian Lee, Beom Kyung Kim, Jin-Ha Yoon
    JHEP Reports.2025; 7(4): 101313.     CrossRef
  • Performance of Noninvasive Indices for Discrimination of Metabolic Dysfunction-Associated Steatotic Liver Disease in Young Adults
    Jaejun Lee, Chang In Han, Dong Yeup Lee, Pil Soo Sung, Si Hyun Bae, Hyun Yang
    Gut and Liver.2025; 19(1): 116.     CrossRef
  • Optimal BMI cutoff for lean MASLD/MetALD and adverse hepatic outcomes in East-Asian populations
    Byungyoon Yun, Juyeon Oh, Heejoo Park, Beom Kyung Kim, Jin-Ha Yoon
    European Journal of Internal Medicine.2025; 133: 141.     CrossRef
  • Cigarette Smoke Contributes to the Progression of MASLD: From the Molecular Mechanisms to Therapy
    Jiatong Xu, Yifan Li, Zixuan Feng, Hongping Chen
    Cells.2025; 14(3): 221.     CrossRef
  • Psychosocial risks in metabolic dysfunction-associated steatotic liver disease
    Hanne Åström, Christine Takami Lageborn, Hannes Hagström
    Expert Review of Gastroenterology & Hepatology.2025; 19(3): 273.     CrossRef
  • Is type 2 diabetes a link between lung function and metabolic dysfunction–associated steatotic liver disease? Insights from population studies and Mendelian randomization
    Runmin Cao, Yurun Zhang, Ling Cao, Honghe Jiang
    European Journal of Gastroenterology & Hepatology.2025; 37(5): 652.     CrossRef
  • A novel 11β-HSD1 inhibitor ameliorates liver fibrosis by inhibiting the notch signaling pathway and increasing NK cell population
    Ji Eun Kim, Yun Kim, Jiwon Bae, Eileen Laurel Yoon, Hyun Sung Kim, Sung Ryol Lee, Tae Hyun Yoon, Dae Won Jun
    Archives of Pharmacal Research.2025; 48(2): 166.     CrossRef
  • Molecular Clustering of Metabolic Dysfunction-Associated Steatotic Liver Disease Based on Transcriptome Analysis
    Gina Ryu, Eileen Laurel Yoon, Wankyu Kim, Dae Won Jun
    Diagnostics.2025; 15(3): 342.     CrossRef
  • Dietary Patterns Rich in Soybean Products, Vegetables, Fish, Fruits, and Miso Soup Were Inversely Associated with Fatty Liver Index: The Nagahama Study
    Yoko UEBA, Kaori IKEDA, Yasuharu TABARA, Takeo NAKAYAMA, Daisuke TANAKA, Yoshimitsu TAKAHASHI, Shinji KOSUGI, Kazuya SETOH, Takahisa KAWAGUCHI, Fumihiko MATSUDA, Nobuya INAGAKI
    Journal of Nutritional Science and Vitaminology.2025; 71(1): 25.     CrossRef
  • Identification of Novel Therapeutic Targets for MAFLD Based on Bioinformatics Analysis Combined with Mendelian Randomization
    Jialin Ren, Min Wu
    International Journal of Molecular Sciences.2025; 26(7): 3166.     CrossRef
  • Comparative Hepatic Outcomes of SGLT2i or DPP4i Compared to GLP‐1RA in CHB and T2DM Patients
    Byungyoon Yun, Juyeon Oh, Heejoo Park, Jian Lee, Beom Kyung Kim, Jin‐Ha Yoon
    Liver International.2025;[Epub]     CrossRef
  • Future Perspectives of Liver Research in the Asia‐Pacific Region: Focus on Hepatitis B and C
    Beom Kyung Kim
    Journal of Gastroenterology and Hepatology.2025; 40(8): 1855.     CrossRef
  • Navigating the Paradox of IL‐22: Friend or Foe in Hepatic Health?
    Jianqi Qin, Weixiong Zhu, Wence Zhou
    Journal of Gastroenterology and Hepatology.2025; 40(6): 1393.     CrossRef
  • Metabolic Dysfunction-Associated Steatotic Liver Disease, Recent Revision of Terminology and Its Implications
    Hyo Young Lee, Eileen L. Yoon
    The Korean Journal of Gastroenterology.2025; 85(2): 126.     CrossRef
  • Young Adults With Metabolic Dysfunction–Associated Steatotic Liver Disease Have an Increased Risk of Early-Onset Cancer: A Nationwide Cohort Study Differentiating the Risk of 23 Site-Specific Cancers
    Joon Ho Moon, Seogsong Jeong, Heejoon Jang, Dong Hyeon Lee, Sae Kyung Joo, Bo Kyung Koo, Qiang Xia, Meng Sha, Yoosoo Chang, Won Kim
    Clinical Gastroenterology and Hepatology.2025; 23(13): 2540.     CrossRef
  • The Role of Global Physical Capacity Score in Key Parameters of Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)
    Nicola Verrelli, Caterina Bonfiglio, Isabella Franco, Claudia Beatrice Bagnato, Dolores Stabile, Endrit Shahini, Antonella Bianco
    Journal of Clinical Medicine.2025; 14(11): 3821.     CrossRef
  • Cost-effectiveness analysis of MASLD screening using FIB-4 based two-step algorithm in the medical check-up
    Mimi Kim, Huiyul Park, Eileen L. Yoon, Ramsey Cheung, Donghee Kim, Hye-Lin Kim, Dae Won Jun
    Scientific Reports.2025;[Epub]     CrossRef
  • Gut-Liver Axis: The Role of Intestinal Microbiota and Their Metabolites in the Progression of Metabolic Dysfunction-Associated Steatotic Liver Disease
    Chao Cui, Shuai Gao, Jingfei Shi, Kai Wang
    Gut and Liver.2025; 19(4): 479.     CrossRef
  • Comparison of the Efficacy of Dipeptidyl Peptidase-4 Inhibitors and Sodium-Glucose Cotransporter-2 Inhibitors in Diabetic Patients with Steatotic Liver Disease
    Yunmi Ko, Moon Haeng Hur, Youngsu Park, Jeayeon Park, Hyunjae Shin, Yun Bin Lee, Eun Ju Cho, Jeong-Hoon Lee, Su Jong Yu, Jung-Hwan Yoon, Yoon Jun Kim
    Gut and Liver.2025; 19(5): 758.     CrossRef
  • Misclassification of Alcohol Use Disorder in MASLD and MetALD: Prevalence, Clinical Characteristics, and Outcomes
    Jun-Hyuk Lee, Sung-Ho Ahn, Jimin Park, So Young Jeon, Eileen L. Yoon, Hye Sun Lee, Dae Won Jun
    Gut and Liver.2025; 19(5): 735.     CrossRef
  • Paired snRNA-seq and scRNA-seq analysis of MASLD patients to identify early-stage markers for disease progression
    Suebin Park, Su-Hyeon Lee, Se-eun Han, Beom Kyung Kim, Byungjin Hwang
    Hepatology Communications.2025;[Epub]     CrossRef
  • Changing from NAFLD to MASLD: Similar prognosis of unresectable extrahepatic gastrointestinal cancer under chemotherapy between NAFLD and MASLD
    Hiroyuki Suzuki, Toshimitsu Tanaka, Shotaro Yamaguchi, Keisuke Miwa, Takumi Kawaguchi
    Journal of Hepatology.2024; 80(4): e150.     CrossRef
  • Three-Step Algorithm for Screening High-Risk Group of Metabolic Dysfunction-Associated Steatotic Liver Disease in General Population
    Joo Hyun Oh, Dae Won Jun
    Gut and Liver.2024; 18(2): 197.     CrossRef
  • Changing from NAFLD to MASLD: Similar prognosis of patients with HCC under atezolizumab/bevacizumab treatment between NAFLD and MASLD
    Hiroyuki Suzuki, Shigeo Shimose, Hideki Iwamoto, Takashi Niizeki, Takumi Kawaguchi
    Clinical and Molecular Hepatology.2024; 30(2): 263.     CrossRef
  • Clinical impact of five cardiometabolic risk factors in metabolic dysfunction-associated steatotic liver disease (MASLD): Insights into regional and ethnic differences
    Joo Hyun Oh, Dae Won Jun
    Clinical and Molecular Hepatology.2024; 30(2): 168.     CrossRef
  • Similar respiratory function including chronic obstructive pulmonary disease between non-alcoholic fatty liver disease and metabolic dysfunction-associated steatotic liver disease
    Tsubasa Tsutsumi, Dan Nakano, Machiko Kawaguchi, Hirokazu Takahashi, Takumi Kawaguchi
    Clinical and Molecular Hepatology.2024; 30(2): 266.     CrossRef
  • Prognosis of biopsy-confirmed metabolic dysfunction- associated steatotic liver disease: A sub-analysis of the CLIONE study
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    Clinical and Molecular Hepatology.2024; 30(2): 225.     CrossRef
  • Changes in the terminology and diagnostic criteria of non-alcoholic fatty liver disease: Implications and opportunities
    Muhammed Mubarak
    World Journal of Gastrointestinal Pathophysiology.2024;[Epub]     CrossRef
  • Diagnostic performances of Fibrosis‐4 index and nonalcoholic fatty liver disease fibrosis score in metabolic dysfunction‐associated steatotic liver disease in Asian primary care clinics
    Huiyul Park, Mimi Kim, Hye‐Lin Kim, Seon Cho, Eileen L. Yoon, Dae Won Jun
    Hepatology Research.2024; 54(11): 1027.     CrossRef
  • Metabolic dysfunction-associated steatotic liver disease: Evolution of the final terminology
    Piero Portincasa, Gyorgy Baffy
    European Journal of Internal Medicine.2024; 124: 35.     CrossRef
  • Revisiting the steatosis‐associated fibrosis estimator score in young Asian subjects with steatotic liver disease and consideration for population variability
    Jiwon Yang, Won‐Mook Choi, Danbi Lee, Ju Hyun Shim, Kang Mo Kim, Young‐Suk Lim, Han Chu Lee, Jonggi Choi
    Journal of Gastroenterology and Hepatology.2024; 39(10): 2112.     CrossRef
  • Barriers to care linkage and educational impact on unnecessary MASLD referrals
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    Frontiers in Medicine.2024;[Epub]     CrossRef
  • A New Korean Nomenclature for Steatotic Liver Disease

    The Korean Journal of Gastroenterology.2024; 84(1): 1.     CrossRef
  • A New Korean Nomenclature for Steatotic Liver Disease

    The Korean Journal of Medicine.2024; 99(4): 189.     CrossRef
  • Metabolic Dysfunction-Associated Steatotic Liver Disease Is Associated with Increased Risk of Kidney Cancer: A Nationwide Study
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    Cancers.2024; 16(18): 3161.     CrossRef
  • A New Korean Nomenclature for Steatotic Liver Disease

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  • A new Korean nomenclature for steatotic liver disease

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  • Combi-Elastography versus Transient Elastography for Assessing the Histological Severity of Metabolic Dysfunction-Associated Steatotic Liver Disease
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    Gut and Liver.2024; 18(6): 1048.     CrossRef
  • Establishment and characterization of mouse metabolic dysfunction-associated steatohepatitis-related hepatocellular carcinoma organoids
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    Scientific Reports.2024;[Epub]     CrossRef
  • Metabolic Dysfunction-associated Steatotic Liver Disease–related Hepatocellular Carcinoma: Current Research Insights
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    Journal of Digestive Cancer Research.2024; 12(3): 184.     CrossRef
  • From metabolic dysfunction-associated fatty liver disease to metabolic dysfunction-associated steatotic liver disease: Controversy and consensus
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  • Letter regarding “Waiting for the changes after the adoption of steatotic liver disease”
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  • Correspondence on Letter regarding “Waiting for the changes after the adoption of steatotic liver disease”
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    Clinical and Molecular Hepatology.2023; 30(1): 126.     CrossRef
  • Changing from NAFLD to MASLD: Similar cumulative incidence of reflux esophagitis between NAFLD and MASLD
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    Clinical and Molecular Hepatology.2023; 30(1): 121.     CrossRef
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Editorial

Steatotic liver disease

Citations

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    Xuanlin Wu, Tao Pan, Zhihao Fang, Titi Hui, Xiaoxiao Yu, Changxu Liu, Zihao Guo, Chang Liu
    Journal of Inflammation Research.2025; Volume 18: 1639.     CrossRef
  • Molecular Clustering of Metabolic Dysfunction-Associated Steatotic Liver Disease Based on Transcriptome Analysis
    Gina Ryu, Eileen Laurel Yoon, Wankyu Kim, Dae Won Jun
    Diagnostics.2025; 15(3): 342.     CrossRef
  • Metabolic Dysfunction-Associated Steatotic Liver Disease, Recent Revision of Terminology and Its Implications
    Hyo Young Lee, Eileen L. Yoon
    The Korean Journal of Gastroenterology.2025; 85(2): 126.     CrossRef
  • Association of elevated Alpha-1-Acid glycoprotein with MAFLD prevalence in young and middle-aged women: a cross-sectional study based on NHANES 2017–2020
    Yi Xiao, Xian Luo, Yinghao Fu, Haijuan Huang, Qiaoping Gao, Jiansong Liu, Daxin Pang, Xiaolu Liang, Huadi Chen, Hao Xu
    Diabetology & Metabolic Syndrome.2025;[Epub]     CrossRef
  • The emerging phenotype of nonalcoholic fatty liver disease in lean individuals: what’s different?
    Priyankar Dey
    Frontiers in Endocrinology.2025;[Epub]     CrossRef
  • Laboratory monitoring in patients with moderate to severe plaque psoriasis
    Jonathan M. Fenkel, John A. Osborne, April W. Armstrong, Bruce Strober, Linda Stein Gold, Michael Cameron, Mark Lebwohl
    Journal of Dermatological Treatment.2025;[Epub]     CrossRef
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Reviews

Chronic hepatitis B with concurrent metabolic dysfunction-associated fatty liver disease: Challenges and perspectives
Shang-Chin Huang, Chun-Jen Liu
Clin Mol Hepatol 2023;29(2):320-331.
Published online February 1, 2023
DOI: https://doi.org/10.3350/cmh.2022.0422
The prevalence of metabolic dysfunction-associated fatty liver disease (MAFLD) has increased among the general population and chronic hepatitis B (CHB) patients worldwide. Although fatty liver disease is a well-known risk factor for adverse liver outcomes like cirrhosis and hepatocellular carcinoma, its interactions with the hepatitis B virus (HBV) and clinical impacts seem complex. The presence of hepatic steatosis may suppress HBV viral activity, potentially leading to attenuated liver injury. In contrast, the associated co-morbidities like diabetes mellitus or obesity may increase the risk of developing adverse liver outcomes. These findings implicate that components of MAFLD may have diverse effects on the clinical manifestations of CHB. To this end, a clinical strategy is proposed for managing patients with concurrent CHB and MAFLD. This review article discusses the updated evidence regarding disease prevalence, interactions between steatosis and HBV, clinical impacts, and management strategies, aiming at optimizing holistic health care in the CHB population.

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Citations to this article as recorded by  Crossref logo
  • Unraveling the metabolic thread: Type 2 diabetes and fibrosis in chronic hepatitis B with steatosis
    Won-Mook Choi, Wai-Kay Seto
    Hepatology.2026; 83(5): 1046.     CrossRef
  • Risk Factors of Metabolic Dysfunction-associated Steatotic Liver Disease in a Cohort of Patients With Chronic Hepatitis B
    Maria Kalafateli, Roberta Forlano, Eleanor Barnes, Laura Martinez-Gili, Madeleine Lacey, Giordano Sigon, Benjamin H. Mullish, Vincent Mallet, Lucia Parlati, Paul Richardson, Niamh Forde, Gaetano Serviddio, Rosanna Villani, Sabela Lens, Maria Buti, Elena V
    Clinical Gastroenterology and Hepatology.2026; 24(3): 701.     CrossRef
  • Triglyceride-based lipotoxicity in the pathophysiology of chronic diseases
    Junjun Liu, Xiude Fan, Yongfeng Song, Jiajun Zhao
    Trends in Endocrinology & Metabolism.2026; 37(4): 371.     CrossRef
  • CRISPR: a precise genome editing strategy for the treatment of hepatocellular carcinoma
    Subhrojyoti Mukherjee, Manish Kumar
    Expert Review of Anticancer Therapy.2026; 26(5): 599.     CrossRef
  • Metabolic health in antiviral era of chronic hepatitis B: Editorial on “Impacts of metabolic syndrome diseases on long-term outcomes of chronic hepatitis B patients treated with nucleos(t)ide analogues”
    Shang-Chin Huang, Jia-Horng Kao
    Clinical and Molecular Hepatology.2026; 32(1): 423.     CrossRef
  • The impact of metabolic dysfunction-associated steatotic liver disease on the efficacy of pegylated interferon-based therapy in patients with chronic hepatitis B
    Jiaxin Han, Lianxin Xu, Yuqin Li, Ziling Wang, Minghui Zeng, Jieru Gao, Yuqiang Mi, Wentao Kuai, Huiling Xiang, Liang Xu
    Frontiers in Immunology.2026;[Epub]     CrossRef
  • Association between fatty liver and risk of liver failure in patients with acute hepatitis B: a retrospective cohort study
    Xiao-hao Wang, Yu-nan Chang, Lu Zhang, Yan-li Yang, Lu-wen Liang, Yi Zeng, Zhi Zhou, Shan Zhong, Hu Li
    Frontiers in Cellular and Infection Microbiology.2026;[Epub]     CrossRef
  • Viral hepatitis and liver disease in the Mongolian community in London ('MoLo'): A mixed methods study protocol to investigate the epidemiology and burden of disease to inform clinical and public health interventions
    Emily Martyn, Nara Dashdorj, Jessica Carter, Indrajit Ghosh, Enkh-Oyun Amarbayasgalan, Khadija Said Mohammed, Elizabeth Waddilove, Marion Delphin, Kathryn Jack, Camila Picchio, Joy Ko, Michelle Berkeley, Rubin Rose-Key, Eleni Nastouli, Sema Mandal, Monica
    Wellcome Open Research.2026; 11: 72.     CrossRef
  • Clinical and histopathological features of chronic hepatitis B with normal alanine aminotransferase levels with or without concomitant non-alcoholic fatty liver disease
    Wencong Li, Shiheng Liu, Weiguang Ren, Xiaoxiao Zhang, Lingdi Liu, Fang Han, Ying Zhang, Yuemin Nan, Suxian Zhao
    Frontiers in Medicine.2026;[Epub]     CrossRef
  • Association between diabetes and in‐hospital outcomes in patients with metabolic dysfunction‐associated steatotic liver disease hospitalized for cardiovascular disease: A nationwide database study
    Soichi Komaki, Michikazu Nakai, Yunosuke Matsuura, Kinuko Yamamoto, Hiroki Tanaka, Yuri Komaki, Masashi Yamaguchi, Kohei Moribayashi, Takeshi Ideguchi, Hiroshi Kawakami, Toshihiro Tsuruda, Koichi Kaikita
    Diabetic Medicine.2026;[Epub]     CrossRef
  • Hepatitis B virus exposure and metabolic dysfunction-associated steatotic liver disease in U.S. adults: A nationally representative analysis from NHANES 2017-2020
    Youping Lin, Yanjuan Song, Qiuming Lin, Minran Li
    The American Journal of the Medical Sciences.2026; 372(1): 52.     CrossRef
  • Nomogram integrating serological markers and clinical parameters for predicting severe hepatic steatosis in patients with abnormal glucose metabolism
    Ping Hu, Ao Zhong, Yuting Shen, Yinchen Yuan, Qing Jin, Quan Chen
    Diabetology & Metabolic Syndrome.2026;[Epub]     CrossRef
  • Steatosis paradox: Unraveling pathways of suppressive effect of hepatic steatosis on hepatitis B virus
    Shang-Chin Huang, Jia-Horng Kao
    Biomedical Journal.2026; 49(3): 100969.     CrossRef
  • Periodontitis and Chronic Liver Disease: Mechanistic Insights Focusing on Porphyromonas gingivalis—A Narrative Review
    Yue Ying, Yuwei Nie, Jiahui Zhao, Qin Dong, Meixian Chen, Aijia Jiang, Nan Liu, Tong Xu, Junchao Liu, Yaping Pan, Li Lin, Dongmei Zhang
    Microorganisms.2026; 14(4): 736.     CrossRef
  • Predicting the highly imbalanced hepatitis B virus infection outcome in Chinese middle-aged and older adults using an ensemble machine learning approach
    Chen Sun, Xiaohan Yi, Nyi Nyi Soe, Phyu Mon Latt, Biying Wang, Zhongqun Zhao, Zhen Yu, Xianglong Xu
    Discover Public Health.2026;[Epub]     CrossRef
  • The stealthy saboteur: hepatic steatosis and its erosion of APRI and FIB-4 accuracy
    Huaying Zhou, Yuhong Li, Maoping Li, Jing Ma
    Frontiers in Medicine.2026;[Epub]     CrossRef
  • Mechanisms and Management Strategies of Hepatocarcinogenesis Driven by Chronic Hepatitis B Comorbid with Type 2 Diabetes
    Qin Lou, Jiarong Cai, Jianhua Yin
    Microorganisms.2026; 14(4): 853.     CrossRef
  • Treatment strategies for patients with hepatitis B virus infection coexisting with hepatitis C virus or metabolic dysfunction-associated steatotic liver disease
    Chieh Liu, Yi-Fen Shih, Chun-Jen Liu
    Clinical and Molecular Hepatology.2026; 32(2): 565.     CrossRef
  • Retrospective analysis of predictors for significant hepatic inflammation in metabolic-associated fatty liver disease with chronic hepatitis B
    Long Hao Xu, Run Yan He, Yan Neng Kang, Heng Hong Lin, Jia En Yang, Hua Xiao Chen, Xue Ting Huang, Xiao Lu Wu, Bao Hui Pei, Chao Zhou, Min Wang
    PeerJ.2026; 14: e21186.     CrossRef
  • Diagnosing and defining MASLD in people living with chronic hepatitis B
    Emily Martyn, Alejandro Arenas-Pinto, Richard Gilson, Nomathemba Chandiwana, Stuart Flanagan, Douglas MacDonald, Emmanuel A. Tsochatzis, W. D. Francois Venter, Jennifer Manne-Goehler, Philippa C. Matthews
    Communications Medicine.2026;[Epub]     CrossRef
  • Limited Utility of Serum Scores vs. Shear Wave Elastography for Graft Fibrosis in Adult and Pediatric Liver Transplant Recipients
    Si-Rui Wang, Shu-Chun Wang, Zhan-Xiong Yi, En-Hui He, Jun-Feng Zhao, Xiang-Dong Hu
    Ultrasound in Medicine & Biology.2026; 52(8): 1671.     CrossRef
  • The Chronic Hepatitis B and Metabolic Dysfunction-Associated Steatotic Liver Disease Paradox: Friend or Foe?
    Shang-Chin Huang, Tai-Chung Tseng
    Gut and Liver.2026; 20(3): 350.     CrossRef
  • Knowledge, attitude, and practice towards fatty liver disease among the general population in Shanghai, China: a community-based cross-sectional study
    Xue Yang, Hui Chang, Limei Feng, Bin Wang
    Frontiers in Public Health.2026;[Epub]     CrossRef
  • What is the impact of metabolic dysfunction-associated steatotic liver disease (MASLD) on outcomes in people living with chronic hepatitis B (CHB)? An umbrella review protocol
    Emily Martyn, Jessica Carter, Maeve Barlow, Flora Olcott, Indrajit Ghosh, Elizabeth Waddilove, Alejandro Arenas-Pinto, Richard Gilson, Stuart Flanagan, WD Francois Venter, Jennifer Manne-Goehler, Sally Hargreaves, Emmanouil Tsochatizis, Douglas MacDonald,
    Wellcome Open Research.2026; 11: 285.     CrossRef
  • Coexistent Hepatitis B Virus and Metabolic Dysfunction-Associated Steatotic Liver Disease Under the New Definition: A New Era for Established Diseases
    Ahmed Tawheed, Abdulla A. Mahmoud, Hussein Hassan Aly, Mohamed El-Kassas
    Livers.2026; 6(3): 44.     CrossRef
  • Beyond fibrosis: The imperative for dual steatosis and fibrosis assessment in chronic hepatitis B and metabolic dysfunction-associated steatotic liver disease co-pathology
    Francesco Giangregorio, Elisa Civaschi, Samanta Mazzocchi, Davide Romano, Paolo Clini, Esther Centenara, Umberto Casale, Davide Catucci
    World Journal of Hepatology.2026;[Epub]     CrossRef
  • Aloe emodin isolated from Cassiae semen upregulates IFITM1 to suppress hepatitis B virus replication via the interferon signaling pathway
    Xin Wen, Xincan Yu, Yuxin Hu, Jiamin Chen, Dongwei Zhang, Yalin Hou, Shui Liu, Xuemeng Shi, Jun Xu, Felicia Goodrum
    mSphere.2026;[Epub]     CrossRef
  • Metabolic dysfunction-associated fatty liver disease in chronic hepatitis B: dual effects on hepatocarcinogenesis and evolving strategies for risk prediction
    Huihui Tao, Yuxin Duan, Guoyang Yu, Wei Yan, Jianhua Yin
    Frontiers in Immunology.2026;[Epub]     CrossRef
  • The coexistence of MAFLD increases fibrosis burden in patients with chronic hepatitis B
    Alaa Mohamed Mostafa, Yasser Fouad, Nadia Abdelaaty Abdelkader, Omar Magdy, Nehal Refaat Raouf, Mohammed Eslam
    Scientific Reports.2026;[Epub]     CrossRef
  • Pre-Existing and New-Onset Metabolic Dysfunctions Increase Cirrhosis and Its Complication Risks in Chronic Hepatitis B
    Shang-Chin Huang, Tung-Hung Su, Tai-Chung Tseng, Sih-Han Liao, Shih-Jer Hsu, Chun-Ming Hong, Ting-Yuan Lan, Chen-Hua Liu, Hung-Chih Yang, Chun-Jen Liu, Jia-Horng Kao
    American Journal of Gastroenterology.2025; 120(2): 401.     CrossRef
  • Trajectories of hepatic steatosis and incidence of cardiovascular disease over a 29‐year follow‐up
    Ming‐Whei Yu, Wan‐Jung Wu, Chih‐Lin Lin, Chun‐Jen Liu, Wei‐Ya Peng, Pin‐Yu Huang, Yi‐Wen Huang, Jui‐Ting Hu, Hung‐Chuen Chang, Jyh‐Ming Liou
    Hepatology Research.2025; 55(1): 46.     CrossRef
  • All-cause and cause-specific mortality in patients with chronic hepatitis B and concurrent steatotic liver disease
    Shang-Chin Huang, Tung-Hung Su, Tai-Chung Tseng, Shih-Jer Hsu, Chun-Ming Hong, Ting-Yuan Lan, Chen-Hua Liu, Hung-Chih Yang, Chun-Jen Liu, Jia-Horng Kao
    Journal of Hepatology.2025; 83(1): 43.     CrossRef
  • Hepatitis B virus infection and metabolic dysfunction associated steatotic liver disease: Rising pandemic with complex interaction
    Ammara A Majeed, Amna S Butt
    World Journal of Hepatology.2025;[Epub]     CrossRef
  • Impact of Metabolic Dysfunction-Associated Fatty/Steatotic Liver Disease on Hepatocellular Carcinoma Incidence and Long-Term Prognosis Post-Liver Resection: A Systematic Review and Meta-Analysis
    Qingyan Kong, Diao Kong, Bei Li, Wei Peng, Zheyu Chen
    Academic Radiology.2025; 32(11): 6514.     CrossRef
  • Hepatocellular carcinoma surveillance after sustained virological response in chronic hepatitis C: Editorial on “Non-invasive prediction of post-sustained virological response hepatocellular carcinoma in hepatitis C virus: A systematic review and meta-ana
    Ho Soo Chun, Minjong Lee
    Clinical and Molecular Hepatology.2025; 31(1): 261.     CrossRef
  • Inflammatory Indices and MAFLD Prevalence in Hypertensive Patients: A Large-Scale Cross-Sectional Analysis from China
    Di Shen, Xintian Cai, Junli Hu, Shuaiwei Song, Qing Zhu, Huimin Ma, Yingying Zhang, Rui Ma, Pan Zhou, Wenbo Yang, Jing Hong, Delian Zhang, Nanfang Li
    Journal of Inflammation Research.2025; Volume 18: 1623.     CrossRef
  • Divergent roles of MASLD components in chronic hepatitis B: A double-edged sword
    Shang-Chin Huang, Tung-Hung Su
    Journal of Hepatology.2025; 83(1): e34.     CrossRef
  • Pathogenic Mechanisms of Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)-Associated Hepatocellular Carcinoma
    Toru Nakamura, Atsutaka Masuda, Dan Nakano, Keisuke Amano, Tomoya Sano, Masahito Nakano, Takumi Kawaguchi
    Cells.2025; 14(6): 428.     CrossRef
  • Association of concomitant MASLD and hepatitis B virus with clinical prognosis in hepatocellular carcinoma after curative resection
    Chih-Jan Ko
    American Journal of Cancer Research.2025; 15(2): 737.     CrossRef
  • Mechanisms of hepatocellular carcinoma and cirrhosis development in concurrent steatotic liver disease and chronic hepatitis B
    Saisai Zhang, Lung-Yi Mak, Man-Fung Yuen, Wai-Kay Seto
    Clinical and Molecular Hepatology.2025; 31(Suppl): S182.     CrossRef
  • SLC22A1 Resists Hepatitis B Virus by Activating the JAK/STAT Pathway and Predicts the Effect of Pegylated Interferon α–Based Therapy on Chronic Hepatitis B
    Huiying Yu, Bin Li, Huili Guo, Lin Li, Xiaoquan Liu, Lili Wu, Na Gao, Qiyi Zhao, Xiuqing Pang, Zhiliang Gao
    The Journal of Infectious Diseases.2025; 232(2): 474.     CrossRef
  • Safety of tenofovir alafenamide in the context of hyperlipidemia and cardiovascular diseases: a nationwide analysis
    Jae-Young Kim, Hyuk Kim, Jeong-Ju Yoo, Sang Gyune Kim, Young-Seok Kim
    Hepatology International.2025; 19(4): 959.     CrossRef
  • Non-invasive Assessment of Advanced Fibrosis and Steatosis in Chronic Hepatitis B Patients with Comorbid NAFLD
    Zhenhua Zhou, Feng Chen, Rongrong Zou, Qianhui Li, Xiaomin Xu
    Hepatitis Monthly.2025;[Epub]     CrossRef
  • Study on Ultrasound-Assisted Diagnosis of CHB Complicated with NAFLD Hepatic Fibrosis Based on Deep Learning
    Xiuling Huang, Shan Huang, Changfeng Dong, Nuo Chen, Yuxuan Wang, Changmiao Wang, Yongquan Zhang, Cheng Feng
    Journal of Imaging Informatics in Medicine.2025; 38(6): 4349.     CrossRef
  • Unraveling Demographic Patterns in Hepatitis B Clinical and Laboratory Profiles: Insights From a Ghanaian Cohort: A Retrospective Study
    Napoleon Bellua Sam, Saeed Folorunsho Majeed, Adams Dramani
    Health Science Reports.2025;[Epub]     CrossRef
  • Molecular mechanisms of pyroptosis in non-alcoholic steatohepatitis and feasible diagnosis and treatment strategies
    Dong-fang Shang, Wen-qian Xu, Qing Zhao, Chen-lu Zhao, Si-ying Wang, Yong-li Han, He-guo Li, Ming-hao Liu, Wen-xia Zhao
    Pharmacological Research.2025; 216: 107754.     CrossRef
  • Racing toward the future of chronic hepatitis B management: Achieving functional cure and enhancing hepatocellular carcinoma surveillance through precision medicine
    Yaru Shi, Rong Fan
    Interdisciplinary Medicine.2025;[Epub]     CrossRef
  • The Associations of Serum Folate Forms with Metabolic Dysfunction-Associated Fatty Liver Disease and Liver Fibrosis: A Nationwide Cross-Sectional Study
    Hai Zhao, Wei Fan, Yan Yan, Yuxing Liu, Xuejun Kang
    Metabolites.2025; 15(6): 370.     CrossRef
  • Managing Metabolic Dysfunction-associated Steatotic Liver Disease (MASLD) in Primary Care Settings: A Review
    Vignesh Rajan, Ambarish Das, J. Venkatachalam, K. K. Lohani, Chandrakant Lahariya
    Preventive Medicine: Research & Reviews.2025; 2(4): 183.     CrossRef
  • Hepatitis B virus promotes liver cancer by modulating the immune response to environmental carcinogens
    Mei Huang, Dongyao Wang, Jiao Huang, An-Na Bae, Yun Xia, Xutu Zhao, Mahsa Mortaja, Marjan Azin, Michael R. Collier, Yevgeniy R. Semenov, Jong Ho Park, Shadmehr Demehri
    Nature Communications.2025;[Epub]     CrossRef
  • Natural active botanical metabolites: targeting AMPK signaling pathway to treat metabolic dysfunction-associated fatty liver disease
    Hualing Wang, Xinyu Liu, Chunyi Wang, Shishuang Yu, Xiuli Yang, Xiyu Cao, Maocai Luo, Shiwei Liu, Chuantao Zhang
    Frontiers in Pharmacology.2025;[Epub]     CrossRef
  • The Role of Chinese Medicine in the Treatment of Chronic Hepatitis B
    Shihao Zheng, Qiuyue Wang, Wenying Qi, Jinchi Xie, Xiaobin Zao, Xiaoke Li, Peng Zhang, Yongan Ye
    The American Journal of Chinese Medicine.2025; 53(05): 1285.     CrossRef
  • Steatotic Liver Disease‐Related Polygenetic Risk Score Prediction of Hepatocellular Carcinoma in Nucleotide/Nucleoside Analog‐Treated Chronic Hepatitis B
    Tyng‐Yuan Jang, Chih‐Wen Wang, Po‐Cheng Liang, Yu‐Ju Wei, Ming‐Lun Yeh, Yi‐Hung Lin, Chao‐Kuan Huang, Pei‐Chien Tsai, Yu‐Min Ko, Yi‐Shan Tsai, Kuan‐Yu Chen, Ching‐Chih Lin, Zu‐Yau Lin, Jee‐Fu Huang, Chia‐Yen Dai, Chung‐Feng Huang, Wan‐Long Chuang, Ming‐Lu
    Journal of Gastroenterology and Hepatology.2025; 40(9): 2290.     CrossRef
  • Association between dietary inflammatory index and hepatic steatosis: cross-sectional evidence from the NHANES 2007–2020
    Zhounan Wu, Yuhang Liang, Li Zeng, Jiayi Fang, Jinshen He
    Journal of Health, Population and Nutrition.2025;[Epub]     CrossRef
  • HBV and host metabolic crosstalk: Reprogramming pathways for viral replication and pathogenesis
    YanYing Yan, Zhiqiang Wei, Min Zheng, Mengji Lu, Xueyu Wang
    Virologica Sinica.2025; 40(5): 685.     CrossRef
  • Predictive Value of Hepatic Steatosis for Postoperative Recurrence in Hepatitis B-Related Hepatocellular Carcinoma: Development of a Machine Learning-Based Prognostic Model
    Aoyun Hao, Changlei Li, Ruitao Sun, Bin Tan, Guanming Shao, Kun Li, Na Li, Weiyu Hu, Chao Qu, Jingyu Cao
    Journal of Hepatocellular Carcinoma.2025; Volume 12: 2459.     CrossRef
  • Identification and Validation of Lipid Metabolism-Related Biomarkers GPD1 and CEBPD in Metabolic Dysfunction-Associated Steatohepatitis
    Jianyu Zhou, Chunying Xiao, Bin Huang, Fenfang Chen
    Journal of Inflammation Research.2025; Volume 18: 14805.     CrossRef
  • Knowledge, attitudes, and practices toward fatty liver disease in patients with hepatitis B combined fatty liver disease
    Qian Li, Yongping Qiu, Lang Xiao, Lijian Ran, Hongli Deng, Xin Lu, Shilian Li, Yan Guo, Maolan Fu, Xuqing Zhang, Jie Xia, Huimin Liu
    Scientific Reports.2025;[Epub]     CrossRef
  • Effects of Non-Alcoholic Fatty Liver Disease on Baseline Histology and 96-Week Entecavir Response in Treatment-Naïve Chronic Hepatitis B
    Xiaohui Gu, Weiguang Yang, Yue Hu, Yixin Li, Liwei Zheng, Bei Jiang
    Infection and Drug Resistance.2025; Volume 18: 6817.     CrossRef
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    Hepatology Research.2024; 54(2): 131.     CrossRef
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    Journal of Gastroenterology and Hepatology.2024; 39(1): 193.     CrossRef
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    BMC Public Health.2024;[Epub]     CrossRef
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    Clinical Gastroenterology and Hepatology.2024; 22(6): 1275.     CrossRef
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    Scientific Reports.2024;[Epub]     CrossRef
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    Ağrı Tıp Fakültesi Dergisi.2024; 2(3): 113.     CrossRef
  • Effect of dyslipidemia on HBsAg clearance in nucleos(t)ide analogues-experienced chronic hepatitis B patients treated with peginterferon alfa
    Kaimin Song, Lan Ren, Yunyun Qian, Huitong Wang, Zhixiang Guo, Huatang Zhang, Yijie Lin, Yijuan Zheng, Dawu Zeng, Yongjun Zhou, Zhijun Su, Xueping Yu
    BMC Infectious Diseases.2024;[Epub]     CrossRef
  • Effect of tenofovir versus entecavir on the long-term prognosis in hepatocellular carcinoma patients with concurrent metabolic dysfunction-associated steatotic liver disease and hepatitis B
    Qingyan Kong, Qianqian Gao, Wenjie Li, Zheyu Chen
    Asian Journal of Surgery.2024; 47(11): 4725.     CrossRef
  • Retrospective cohort evaluation study in terms of cardiovascular and metabolic diseases in chronic hepatitis B patients
    Aysun Yakut
    Frontiers in Endocrinology.2024;[Epub]     CrossRef
  • An insight into the updated pharmacotherapy of metabolic-associated fatty liver disease (MAFLD) or metabolic dysfunction-associated steatohepatitis (MASH) in lean individuals: a review
    Sanjay Bandyopadhyay, Shambo Samrat Samajdar, Sirshendu Chaudhuri, Saibal Das
    Hospital Practice.2024; 52(4-5): 123.     CrossRef
  • Impact of concurrent MASLD on early-stage HCC following curative resection in chronic hepatitis B
    Cao-Ngoc Huynh
    American Journal of Cancer Research.2024; 14(9): 4567.     CrossRef
  • Obesity and risk for liver disease: a two-sample Mendelian randomisation study
    Wen An, Jing Luo, Zhe Yu, Mengqi Li, Herui Wei, Aqian Song, Yuanpeng Mao, Hao Bian, Lingling He, Fan Xiao, Hongshan Wei
    British Journal of Nutrition.2024; 132(10): 1403.     CrossRef
  • Comparison of lipid profile alterations in chronic hepatitis b patients receiving tenofovir alafenamide or tenofovir disoproxil fumarate
    Shenglong Lin, Wanlong Huang, Ziyuan Liao, Huaxi Ma, Wenjun Wu, Minghua Lin, Defu Huang, Haibing Gao
    Scientific Reports.2024;[Epub]     CrossRef
  • Revolutionizing the understanding of liver disease: Metabolism, function and future
    Arnulfo E Morales-Galicia, Mariana M Ramírez-Mejía, Guadalupe Ponciano-Rodriguez, Nahum Méndez-Sánchez
    World Journal of Hepatology.2024; 16(12): 1365.     CrossRef
  • Changing the nomenclature from nonalcoholic fatty liver disease to metabolic dysfunction-associated fatty liver disease is more than a change in terminology
    Eileen Laurel Yoon, Dae Won Jun
    Clinical and Molecular Hepatology.2023; 29(2): 371.     CrossRef
  • Distinct effects of hepatic steatosis and metabolic dysfunction on the risk of hepatocellular carcinoma in chronic hepatitis B
    Shang-Chin Huang, Tung-Hung Su, Tai-Chung Tseng, Chi-Ling Chen, Shih-Jer Hsu, Sih-Han Liao, Chun-Ming Hong, Chen-Hua Liu, Ting-Yuan Lan, Hung-Chih Yang, Chun-Jen Liu, Pei-Jer Chen, Jia-Horng Kao
    Hepatology International.2023; 17(5): 1139.     CrossRef
  • Reply to: ‘A risk prediction model for hepatocellular carcinoma after hepatitis B surface antigen seroclearance: Has the correct patient cohort been targeted?’
    Hyun Yang, Ji Hoon Kim, Ji Won Han, Soon Kyu Lee, Jeong Won Jang
    Journal of Hepatology.2023; 79(4): e155.     CrossRef
  • Diabetic MAFLD is associated with increased risk of hepatocellular carcinoma and mortality in chronic viral hepatitis patients
    Mi Na Kim, Kyungdo Han, Juhwan Yoo, Seong Gyu Hwang, Xuehong Zhang, Sang Hoon Ahn
    International Journal of Cancer.2023; 153(8): 1448.     CrossRef
  • 20,909 View
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  • 92 Web of Science
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Steatotic liver disease

Liver transplantation for non-alcoholic fatty liver disease: indications and post-transplant management
Sara Battistella, Francesca D’Arcangelo, Marco Grasso, Alberto Zanetto, Martina Gambato, Giacomo Germani, Marco Senzolo, Francesco Paolo Russo, Patrizia Burra
Clin Mol Hepatol 2023;29(Suppl):S286-S301.
Published online December 28, 2022
DOI: https://doi.org/10.3350/cmh.2022.0392
Non-alcoholic fatty liver disease (NAFLD) is currently the fastest growing indication to liver transplantation (LT) in Western Countries, both for end stage liver disease and hepatocellular carcinoma. NAFLD/non-alcoholic steatohepatitis (NASH) is often expression of a systemic metabolic syndrome; therefore, NAFLD/NASH patients require a multidisciplinary approach for a proper pre-surgical evaluation, which is important to achieve a post-transplant outcome comparable to that of other indications to LT. NAFLD/NASH patients are also at higher risk of post-transplant cardiovascular events, diabetes, dyslipidemia, obesity, renal impairment and recurrent NASH. Lifestyle modifications, included diet and physical activity, are key to improve survival and quality of life after transplantation. A tailored immunosuppressive regimen may be proposed in selected patients. Development of new drugs for the treatment of recurrent NASH is awaited.

Citations

Citations to this article as recorded by  Crossref logo
  • Metabolic dysfunction-associated steatotic liver disease management in Saudi Arabia: A modified Delphi-based adaptation of international standards
    Faisal Abaalkhail, Faisal M. Sanai, Khalid AlSwat, Adnan Alzanbagi, Ahmed Aljedai, Ali Alshehri, Assim Alfadda, Hamdan Alghamdi, Majid Almadi, Mohammad Aleissa, Mona Ismail, Saud Alsifri, Turki Alzahrani, Saleh Alqahtani, Waleed Al Hamoudi
    Saudi Journal of Gastroenterology.2026; 32(2): 104.     CrossRef
  • Deep learning-enhanced quantitative evaluation of hepatic ischemia–reperfusion injury and steatosis via near-infrared hyperspectral imaging
    Zichen Wang, Zhan Qu, Chen Chen, Jian Du, Jian Zhang, Tao Li, Jianhua Shi, Chun Zhang, Jianwen Lu, Min Tian, Lu Lu, Boyan Tian, Zhen Zhao, Fan Mu, Lexuan Xu, Xin Zhang, Yimeng Wang, Cuiping Yao, Hao Sun, Yi Lyu, Bo Wang, Liangshuo Hu
    International Journal of Surgery.2026; 112(5): 11274.     CrossRef
  • Rehabilitation challenges and enablers for exercise in post-liver transplant patients with metabolic syndrome: a qualitative study
    Mingyan Shen, Zuxin Shi, Yanping Shen, Pengxia Wan, Xiaoxiao Zhu
    BMC Nursing.2026;[Epub]     CrossRef
  • Effectiveness of nutrition education program and omega-3 supplementation on body weight, liver enzyme, lipid profile among non-alcoholic fatty liver disease patients
    Dilkhosh Shamal Ramadhan, Ibrahim Hasan Mustafa
    BMC Nutrition.2026;[Epub]     CrossRef
  • Liver transplantation in Japan: Achievements, limitations, and future perspectives
    Yasuhiko Sugawara
    BioScience Trends.2026;[Epub]     CrossRef
  • Engineering Immunoregenerative Therapy via an Immunomodulatory Binary Pharmacology Hydrogel Depot for Prolonged Allograft Survival
    Ning Wang, Ruiqi Sun, Yang Fu, Zhonghan Wu, Xinyu Tong, Hong Tang, Wentao Zhao, Zhi Liang, Jintao Zheng, Yanan Guan, Ke Zhou, Penghong Song, Shusen Zheng, Hangxiang Wang, Haiyang Xie
    Advanced Science.2026;[Epub]     CrossRef
  • Examining the prevalence of hepatic steatosis and advanced fibrosis using non-invasive measures across Canada: A national estimate using the Canadian Health Measures Survey (CHMS) from 2009-2019
    Jacob Romano, Jessica Burnside, Giada Sebastiani, Alnoor Ramji, Keyur Patel, Mark Swain, Sahar Saeed
    Annals of Hepatology.2025; 30(1): 101757.     CrossRef
  • Macronutrient Modulation in Metabolic Dysfunction-Associated Steatotic Liver Disease—the Molecular Role of Fatty Acids compared with Sugars in Human Metabolism and Disease Progression
    Sinéad M Mullin, Aidan J Kelly, Méabh B Ní Chathail, Suzanne Norris, Christopher E Shannon, Helen M Roche
    Advances in Nutrition.2025; 16(3): 100375.     CrossRef
  • Metabolic Dysfunction-Associated Steatotic Liver Disease: Pathogenetic Links to Cardiovascular Risk
    Vlad Alexandru Ionescu, Gina Gheorghe, Nicolae Bacalbasa, Camelia Cristina Diaconu
    Biomolecules.2025; 15(2): 163.     CrossRef
  • Metabolic dysfunction-associated steatotic liver disease correlates with higher lower graft survival in liver transplant recipients with hepatocellular carcinoma
    Marwan Alsaqa, Leandro Sierra, Ana Marenco-Flores, Ximena Parraga, Romelia Barba, Daniela Goyes, N. Begum Ozturk, Michael P. Curry, Alan Bonder, Behnam Saberi
    European Journal of Gastroenterology & Hepatology.2025; 37(4): 497.     CrossRef
  • Clinical and Economic Burden of Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) in a Spanish Mediterranean Region: A Population-Based Study
    Javier Díaz Carnicero, Inma Saurí-Ferrer, Josep Redon, Jorge Navarro, Gonzalo Fernández, Carlos Hurtado, Karine Ferreira, Carolina Alvarez-Ortega, Antón Gómez, Carlos J. Martos-Rodríguez, David Martí-Aguado, Desamparados Escudero, Marta Cedenilla
    Journal of Clinical Medicine.2025; 14(7): 2441.     CrossRef
  • MASLD or MAFLD: fatty liver by any name will pose the same challenge
    Anil Chandra Anand, Dibyalochan Praharaj
    Metabolism and Target Organ Damage.2025;[Epub]     CrossRef
  • Cardiac Remodeling and Arrhythmic Burden in Pre-Transplant Cirrhotic Patients: Pathophysiological Mechanisms and Management Strategies
    Charilila-Loukia Ververeli, Yannis Dimitroglou, Stergios Soulaidopoulos, Evangelos Cholongitas, Constantina Aggeli, Konstantinos Tsioufis, Dimitris Tousoulis
    Biomedicines.2025; 13(4): 812.     CrossRef
  • Correspondence to letter to the editor on “Optimal tacrolimus levels for reducing CKD risk and the impact of intrapatient variability on CKD and ESRD development following liver transplantation”
    Soon Kyu Lee, Jong Young Choi
    Clinical and Molecular Hepatology.2025; 31(2): e212.     CrossRef
  • Risk Factors Related to the Development of Nonalcoholic Fatty Liver: A Systematic Review
    Omaira Valencia, Carolina López, Esteban Vanegas-Duarte, Carolina Fillizola, Diana Fernanda Bejarano Ramírez, Nicolás Andrés Cortés Mejía, Alonso Vera Torres, Kevork M. Peltekian
    Canadian Journal of Gastroenterology and Hepatology.2025;[Epub]     CrossRef
  • Safety, efficacy, and outcomes of invasive coronary angiography in liver transplant candidates
    Carme Ginard, Giulia Pagano, Salvatore Brugaletta, Annabel Blasi, Marta Sánchez-Ric, Ander Regueiro, Roger Pujol, Sergio Rodriguez-Tajes, Pablo Ruiz, Jordi Colmenero, Gonzalo Crespo
    JHEP Reports.2025; 7(7): 101428.     CrossRef
  • The Relationships Between MASLD, Extrahepatic Multimorbidity, and All-Cause Mortality in the UK Biobank Cohort
    Qi Feng, Chioma N Izzi-Engbeaya, Andrea D Branch, Benjamin H Mullish, Pinelopi Manousou, Mark Woodward
    The Journal of Clinical Endocrinology & Metabolism.2025; 111(1): e58.     CrossRef
  • MAFLD as a Cardiovascular Risk Factor: An Extended Retrospective Study with a Control Group
    Małgorzata Szymala-Pędzik, Marcin Piersiak, Maciej Pachana, Karolina Lindner-Pawłowicz, Wioletta Szczepaniak, Małgorzata Sobieszczańska
    Journal of Clinical Medicine.2025; 14(12): 4181.     CrossRef
  • Metabolic-associated fatty liver disease: Noninvasive diagnosis and assessment of liver fibrosis
    O. O. Karshina, I. S. Sabirov
    Meditsinskiy sovet = Medical Council.2025; (8): 72.     CrossRef
  • Are we standing on the shifting sands of post-transplant metabolic-associated steatotic liver disease?
    Renata Zatta, Luana S da Silva, Guilherme Felga, Carolina FMG Pimentel
    World Journal of Hepatology.2025;[Epub]     CrossRef
  • Corrected T1 (cT1) is the most appropriate diagnosis and monitoring tool for widespread adoption of resmetirom treatment in the United States
    Marika Hancock, Cayden Beyer, Michael Fuchs, Mukesh Harisinghani, Prasun Jalal, Michael Ndaa, Niharika Samala, Jose D. Vargas, Arjun Jayaswal
    Journal of Medical Economics.2025; 28(1): 1370.     CrossRef
  • Integrated Genomic Analysis Reveals the Synergistic Role of PNPLA3 and ABCC8 Variants in Diabetic MASLD in Pakistan
    Asma Shabbir, Ambrina Khatoon, Zaigham Abbas, Sucheta Srivastava, Talat Mirza
    Medical Sciences.2025; 13(3): 178.     CrossRef
  • Sex-Stratified Prediction Models for 5-Year Nonalcoholic Fatty Liver Disease Risk in Thyroid Cancer Patients: A Nationwide Cohort Study
    Young Bin Cho, Kyoung Sik Park
    Biomedicines.2025; 13(9): 2250.     CrossRef
  • Genome-Based Mexican Diet Bioactives Target Molecular Pathways in HBV, HCV, and MASLD: A Bioinformatic Approach for Liver Disease Prevention
    Leonardo Leal-Mercado, Arturo Panduro, Alexis José-Abrego, Sonia Roman
    International Journal of Molecular Sciences.2025; 26(18): 8977.     CrossRef
  • Validation of MELD 3.0 and ReMELD-Na scoring systems: a German clinical cohort study
    Aghnia J. Putri, Decan Jiang, Zoltan Czigany, Arianeb Mehrabi, Markus Wolfgang Buechler, Uta Merle, Christoph Michalski, Peri Husen
    Langenbeck's Archives of Surgery.2025;[Epub]     CrossRef
  • A Multi-Modal Deep Fusion Network: Enhancing Graft Survival Prediction in Non-Alcoholic Fatty Liver Disease Patients Prior to Liver Transplantation
    Devi Rajeev, S Remya, Anand Nayyar
    IEEE MultiMedia.2025; 32(4): 68.     CrossRef
  • Investigating the Effect of Two Types of Aerobic Exercise on SIRT1 and AMPK Gene Expression Regulation in an Animal Model of Non-Alcoholic Fatty Liver Disease
    Masoumeh Sadat Foroughi Rahaghi, Lida Moradi, Bahram Abedi, Mohammad Ali Azarbaijani
    Journal of Shahrekord University of Medical Sciences.2025; 27(4): 192.     CrossRef
  • How best to combine liver transplantation and bariatric surgery?—Results from a global, web‐based survey
    Jeannette Widmer, Janina Eden, Fariba Abbassi, Roberta Angelico, Fabian Rössler, Beat Müllhaupt, Philipp Dutkowski, Marco Bueter, Andrea Schlegel
    Liver International.2024; 44(2): 566.     CrossRef
  • Exploring the effects of epigallocatechin gallate on lipid metabolism in the rat steatotic liver during normothermic machine perfusion: Insights from lipidomics and RNA sequencing
    Shuxuan Li, Yao Zhi, Wentao Mu, Mingqian Li, Guoyue Lv
    European Journal of Pharmacology.2024; 964: 176300.     CrossRef
  • Exploring the Multifaceted Landscape of MASLD: A Comprehensive Synthesis of Recent Studies, from Pathophysiology to Organoids and Beyond
    Allison Soto, Colby Spongberg, Alessandro Martinino, Francesco Giovinazzo
    Biomedicines.2024; 12(2): 397.     CrossRef
  • Metabolic dysfunction-associated steatotic liver disease: A silent pandemic
    Arghya Samanta, Moinak Sen Sarma
    World Journal of Hepatology.2024; 16(4): 511.     CrossRef
  • Plasma ALS and Gal-3BP differentiate early from advanced liver fibrosis in MASLD patients
    David Pérez Compte, Lucas Etourneau, Anne-Marie Hesse, Alexandra Kraut, Justine Barthelon, Nathalie Sturm, Hélène Borges, Salomé Biennier, Marie Courçon, Marc de Saint Loup, Victoria Mignot, Charlotte Costentin, Thomas Burger, Yohann Couté, Christophe Bru
    Biomarker Research.2024;[Epub]     CrossRef
  • Cardiac abnormalities pre- and post-liver transplantation for metabolic dysfunction-associated steatohepatitis – Evidence and special considerations
    Steven M. Elzein, Elizabeth W. Brombosz, Sudha Kodali
    Journal of Liver Transplantation.2024; 15: 100228.     CrossRef
  • Serum Creatinine as an Independent Predictor of Moderate to Severe Fibrosis in Chinese American Non-obese Metabolic Dysfunction-Associated Steatotic Liver Disease
    Michael Sun, Vincent J Yao, Aivi A Rahman, Kevin Liu, Saud Rehman, Amber Sun, Alan C Yao
    Cureus.2024;[Epub]     CrossRef
  • Recent trends and new developments in liver transplantation
    Yasuhiko Sugawara, Taizo Hibi
    BioScience Trends.2024; 18(3): 206.     CrossRef
  • Cenicriviroc Suppresses and Reverses Steatohepatitis by Regulating Macrophage Infiltration and M2 Polarization in Mice
    Guanliang Chen, Yanwen Yu, Yuqin Zhu, Mayumi Nagashimada, Yajiao Wang, Naoto Nagata, Liang Xu
    Endocrinology.2024;[Epub]     CrossRef
  • Metabolic bariatric surgery, alcohol misuse and liver cirrhosis: a narrative review
    Matthew L. Basa, Danielle S. Cha, David P. Mitchell, Daniel L. Chan
    Metabolism and Target Organ Damage.2024;[Epub]     CrossRef
  • The interrelation of cardiometabolic risk factors and metabolic dysfunction-associated steatotic liver disease subtypes
    A. Yu. Ishchenko, M. Yu. Galushko, I. G. Bakulin
    Meditsinskiy sovet = Medical Council.2024; (15): 146.     CrossRef
  • Cardio-metabolic disorders in a patient with non-alcoholic fatty liver disease and normal body weight
    Svetlana V. Turkina, Mikhail E. Statsenko, Irina A. Tyshchenko, Marina N. Titarenko, Marina A. Kosivtsova, Elena E. Gorbacheva
    Journal of Volgograd State Medical University.2024; 21(3): 109.     CrossRef
  • Exploring the knowledge and attitudes towards metabolic dysfunction associated fatty liver disease (MAFLD): Validation and correlations of MAFLD-knowledge questionnaire and MAFLD-attitude questionnaire
    Samah Al Tawil, Mohamad Abdelkhalik, Adam El Fouani, Nour Allakiss, Lama Mattar, Wissam H. Faour, Rajaa Chatila
    Heliyon.2024; 10(22): e40217.     CrossRef
  • Weight Loss After Sleeve Gastrectomy According to Metabolic Dysfunction-Associated Steatotic Liver Disease Stage in Patients with Obesity: A Liver Biopsy-Based Prospective Study
    José Ignacio Martínez-Montoro, Isabel Arranz-Salas, Carolina Gutiérrez-Repiso, Ana Sánchez-García, Luis Ocaña-Wilhelmi, José M. Pinazo-Bandera, Diego Fernández-García, Araceli Muñoz-Garach, Dieter Morales-García, Miren García-Cortés, Eduardo García-Fuente
    Nutrients.2024; 16(22): 3857.     CrossRef
  • Liver transplantation for alcohol-related liver disease in Korea: The need for patient management guidelines
    Soon Kyu Lee
    Annals of Liver Transplantation.2024; 4(2): 40.     CrossRef
  • Post-transplant complications in alcohol- and metabolic-associated steatotic liver disease
    Shekhar Singh Jadaun, Sanjiv Saigal
    Metabolism and Target Organ Damage.2024;[Epub]     CrossRef
  • How to optimize the outcome of liver transplantation for non-alcoholic fatty liver disease
    Byeong Geun Song, Dong Hyun Sinn
    Clinical and Molecular Hepatology.2023; 29(2): 411.     CrossRef
  • Liver fibrosis and MAFLD: the exploration of multi-drug combination therapy strategies
    Qingfu Dong, Haolin Bao, Jiangang Wang, Wujiang Shi, Xinlei Zou, Jialin Sheng, Jianjun Gao, Canghai Guan, Haoming Xia, Jinglin Li, Pengcheng Kang, Yi Xu, Yunfu Cui, Xiangyu Zhong
    Frontiers in Medicine.2023;[Epub]     CrossRef
  • Diabetes and Metabolic Disorders: Their Impact on Cardiovascular Events in Liver Transplant Patients
    Simone Di Cola, Giulia Cusi, Lucia Lapenna, Jakub Gazda, Stefano Fonte, Marco Mattana, Gianluca Mennini, Patrizio Pasqualetti, Manuela Merli, Xingshun Qi
    Canadian Journal of Gastroenterology and Hepatology.2023; 2023: 1.     CrossRef
  • Evaluation and Management of Nutritional Consequences of Chronic Liver Diseases
    Silvia Espina, Diego Casas-Deza, Vanesa Bernal-Monterde, María José Domper-Arnal, Sandra García-Mateo, Alberto Lué
    Nutrients.2023; 15(15): 3487.     CrossRef
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    Journal of Clinical Medicine.2023; 12(17): 5586.     CrossRef
  • Outcomes in elderly patients undergoing hepatic resection compared to liver transplant for hepatocellular carcinoma
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  • 14,964 View
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Original Article

Forecasted 2040 global prevalence of nonalcoholic fatty liver disease using hierarchical bayesian approach
Michael H. Le, Yee Hui Yeo, Biyao Zou, Scott Barnet, Linda Henry, Ramsey Cheung, Mindie H. Nguyen
Clin Mol Hepatol 2022;28(4):841-850.
Published online September 19, 2022
DOI: https://doi.org/10.3350/cmh.2022.0239
Background/Aims
Due to increases in obesity and type 2 diabetes, the prevalence of nonalcoholic fatty liver disease (NAFLD) has also been increasing. Current forecast models may not include non-obese NAFLD. Here, we used the Bayesian approach to forecast the prevalence of NAFLD through the year 2040.
Methods
Prevalence data from 245 articles involving 2,699,627 persons were used with a hierarchical Bayesian approach to forecast the prevalence of NAFLD through 2040. Subgroup analyses were performed for age, gender, presence of metabolic syndrome, region, and smoking status. Sensitivity analysis was conducted for clinical setting and study quality.
Results
The forecasted 2040 prevalence was 55.7%, a three-fold increase since 1990 and a 43.2% increase from the 2020 prevalence of 38.9%. The estimated average yearly increase since 2020 was 2.16%. For those aged <50 years and ≥50 years, the 2040 prevalence were not significantly different (56.7% vs. 61.5%, P=0.52). There was a significant difference in 2040 prevalence by sex (males: 60% vs. 50%) but the trend was steeper for females (annual percentage change: 2.5% vs. 1.5%, P=0.025). There was no difference in trends overtime by region (P=0.48). The increase rate was significantly higher in those without metabolic syndrome (3.8% vs. 0.84%, P=0.003) and smokers (1.4% vs. 1.1%, P=0.011). There was no difference by clinical/community setting (P=0.491) or study quality (P=0.85).
Conclusion
By 2040, over half the adult population is forecasted to have NAFLD. The largest increases are expected to occur in women, smokers, and those without metabolic syndrome. Intensified efforts are needed to raise awareness of NAFLD and to determine long-term solutions addressing the driving factors of the disease.

Citations

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  • Prevention of liver cancer in the era of next-generation antivirals and obesity epidemic
    Hiroyuki Suzuki, Naoto Fujiwara, Amit G. Singal, Thomas F. Baumert, Raymond T. Chung, Takumi Kawaguchi, Yujin Hoshida
    Hepatology.2026; 84(1): 292.     CrossRef
  • Optimized motion‐insensitive PDFF mapping of the liver
    Jiayi Tang, Daiki Tamada, Raphael do Vale Souza, Aaron Faacks, Jitka Starekova, Julius F. Heidenreich, Lukas Müller, Garrett C. Fullerton, Collin J. Buelo, Jeff Kammerman, Jean H. Brittain, Scott B. Reeder, Diego Hernando
    Magnetic Resonance in Medicine.2026; 95(1): 249.     CrossRef
  • The global cardiovascular–liver–metabolic syndemic: epidemiology, trends and challenges
    Nicholas W. S. Chew, Anurag Mehta, Rachel Goh, Jaycie Koh, Yiming Chen, Bryan Chong, Mark Y. Chan, Muhammad Shahzeb Khan, Mark D. Muthiah, Javed Butler, Arun J. Sanyal, Laurence S. Sperling
    Nature Reviews Cardiology.2026; 23(4): 219.     CrossRef
  • Proanthocyanidins from Iris lactea Pall. var. chinensis (Fisch.) Koidz alleviate non-alcoholic fatty liver disease by regulating lipid metabolism via AMPK/SREBP-1c signalling pathway
    Fangfang Tie, Lichengcheng Ren, Yidan Gao, Yun Wu, Qi Dong, Honglun Wang, Na Hu
    Journal of Ethnopharmacology.2026; 356: 120784.     CrossRef
  • Menopause May Partially Explain Age-Related Increased Risk of MASLD Fibrosis: A Causal Mediation Analysis
    Itunu O. Sokale, Yan Liu, Hashem B. El-Serag, Fasiha Kanwal, Aaron P. Thrift, Maya Balakrishnan
    Clinical Gastroenterology and Hepatology.2026; 24(6): 1729.     CrossRef
  • Impact of SGLT2i and GLP-1RA on liver-related events in patients with MASLD and type 2 diabetes: A network meta-analysis
    Lu Li, Xianhua Mao, Chi Ho Lee, David Tak Wai Lui, Rex Wan-Hin Hui, Lung-Yi Mak, Man-Fung Yuen, Ka Shing Cheung, Wai-Kay Seto
    JHEP Reports.2026; 8(1): 101661.     CrossRef
  • Management of Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD): Facts and Hopes
    Luigi E. Adinolfi, Aldo Marrone, Antonio Izzi, Antonio Craxì
    Journal of Clinical and Experimental Hepatology.2026; 16(1): 103411.     CrossRef
  • Improving surgical treatments for hepatocellular carcinoma
    Abdullah K. Malik, Daniel Geh, Thomas R. Jeffry Evans, Pierce K. H. Chow, Derek A. Mann, Steven A. White
    Nature Reviews Gastroenterology & Hepatology.2026; 23(3): 208.     CrossRef
  • Charge-based supramolecular peptide nanocomplexes for oral delivery via transporter-driven endocytosis
    So-Hyeon Park, Gaeun Ma, Seong Jin Park, Seong-Bin Yang, Minho Seo, Jun-Hyuck Lee, Seho Kweon, Jooho Park
    Biomaterials.2026; 329: 123903.     CrossRef
  • Salty taste preference, genetic susceptibility, and risk of metabolic dysfunction-associated steatotic liver disease: insights from three prospective cohorts
    Shunming Zhang, Yan Yan, Yeqing Gu, Hongmei Wu, Qing Zhang, Li Liu, Yan Borné, Lu Qi, Tao Huang, Yu-Ming Chen, Kaijun Niu, Le Ma, the China Cohort Consortium
    Food & Function.2026; 17(1): 120.     CrossRef
  • Hepatic HMGCS2-derived β-hydroxybutyrate attenuates hippocampal insulin resistance and neuroinflammation to promote MASLD-induced cognitive function
    Lijuan Nie, Jing Sun, Weilong Xu, Xinyi Yang, Gaoxiang Wang, Ying Wang, Tao Jiang, Yutian Cao, Hao Chen, Qingrong Xia, Xiqiao Zhou
    Communications Biology.2026;[Epub]     CrossRef
  • Comparison of diagnostic value of abdominal obesity and metabolism-related indicators for non-alcoholic fatty liver disease in lean individuals
    Hailong Zhang, Meng Guo, Xiao Liang, Dan Wan, Chunli Zhang, Fanfan Liang, Sijia Chen, Qian Wang, Zongfang Li
    BMC Gastroenterology.2026;[Epub]     CrossRef
  • Impact of multidisciplinary steatotic liver disease management on bariatric surgery referral and clinical outcomes: A retrospective cohort study
    Andrew W Schwartz, Emily Y Park, Ysabel C Ilagan-Ying, Zoe E Zimmerman, Bryan Bollinger, Lee D Ying, Yanhong D Deng, Andrew J Duffy, John M Morton, Wajahat Z Mehal, Albert Do, Bubu A Banini
    World Journal of Hepatology.2026;[Epub]     CrossRef
  • CD36–PPARγ–SPP1 axis mediates hepatocyte–macrophage coordination to drive MASLD-related liver fibrosis
    Zhe Dai, Xiaoman Liu, Yining Liang, Guangde Zhou, Fengjuan Chen, Wei Xie, Si-Yi Lei, Li-You Lian, Sui-Dan Chen, Mark Dhinesh Muthiah, Xinshou Ouyang, Ming-Hua Zheng, Yijin Wang
    JHEP Reports.2026; 8(4): 101745.     CrossRef
  • Clinical biomarkers and biosensors for early detection of metabolic dysfunction-associated steatohepatitis (MASH): a translational perspective
    Fareeha Arshad, Raja Chinnappan, Dieter C. Broering, Dimitri Aristotle Raptis, Tanveer Ahmad Mir, Mohammed Imran Khan, Ahmed Yaqinuddin
    Frontiers in Bioengineering and Biotechnology.2026;[Epub]     CrossRef
  • EMMPRIN deficiency alleviated metabolic-associated steatohepatitis progression via regulation of the UBA52–MCT1 axis
    Linying Lai, Baoyuan Huang, Ziping Song, Xinyan Zhu, Wenzhuo Yang
    Frontiers in Pharmacology.2026;[Epub]     CrossRef
  • The Role of Primary Care and Noninvasive Testing in the Early Diagnosis of Metabolic-Associated Steatotic Liver Disease (MASLD)
    Alina Mihaela Constantin, Mirela Maria Nedelescu, Raluca Tatar, Corina Silvia Pop, Andrea Elena Neculau, Sorina Maria Aurelian, Corina Oancea, Justin Aurelian, Sandra Monica Gîdei, Irina Mihaela Stoian
    Gastroenterology Insights.2026; 17(1): 11.     CrossRef
  • Pathogenesis and intervention strategies for metabolic dysfunction–associated fatty liver disease from the perspective of the gut–microbiota–liver axis
    Jiabao Liao, Ze Zhou, You Lv, Yiting Zhang, Siyi Liu, Haixia Tang, Fei Qv, Si Wang, Lianhao Yang, Yanming Lu, Zhixia Yang, Xuehua Xie, Mengqiu Shao
    Frontiers in Immunology.2026;[Epub]     CrossRef
  • Association of Metabolic Dysfunction-Associated Steatotic Liver Disease with Extrahepatic Cancers and Sarcopenia
    Yusuf Yilmaz, Alina M. Allen, Jérôme Boursier, Juan P. Arab
    Clinics in Liver Disease.2026; 30(2): 289.     CrossRef
  • MASH in Type 2 Diabetes: Pathophysiology, Diagnosis, and Therapeutic Management—A Narrative Review
    Adela Gabriela Ştefan, Adina Mitrea, Diana Clenciu, Ionela Mihaela Vladu, Maria Magdalena Roşu, Diana Cristina Protasiewicz-Timofticiuc, Theodora Claudia Radu-Gheonea, Ion-Cristian Efrem, Anca Maria Amzolini, Beatrice Elena Vladu, Ana-Maria Efrem, Delia-V
    Medicina.2026; 62(2): 325.     CrossRef
  • Multi-modal AI for opportunistic screening, staging and progression risk stratification of steatotic liver disease
    Yuan Gao, Chunli Li, Wanxing Chang, Bai Du, Xianghua Ye, Yee Hui Yeo, Yingda Xia, Heng Guo, Xiaoming Zhang, Wei Liu, Ruobing Bai, Beibei Li, Yang Hong, Jiawen Yao, Le Lu, Kai Cao, Ke Yan, Jun Chen, Jie Li, Yang Hou, Ling Zhang, Yu Shi
    Nature Communications.2026;[Epub]     CrossRef
  • From HBV to MASLD Cirrhosis: Mechanistic Insights and Therapeutic Strategies
    Hanqi Yu, Hongfan Ding, Yang Huang, Haoze Cao, Yuan Ding, Weilin Wang
    Portal Hypertension & Cirrhosis.2026; 5(2): 170.     CrossRef
  • From Childhood to Old Age: Current Knowledge and Practical Approaches to Metabolic Dysfunction-Associated Steatotic Liver Disease
    Iwona Gorczyca-Głowacka, Michał Tarnowski, Anna Zmelonek-Znamirowska, Przemysław Wolak
    Journal of Clinical Medicine.2026; 15(4): 1536.     CrossRef
  • Serpina3c protects against metabolic dysfunction-associated steatotic liver disease in offspring induced by prenatal prednisone exposure
    Yongguo Dai, Zhengjie Lu, Yu Peng, Kexin Liu, Xiaoqian Lu, Xiaoxiang Sun, Yuxi Wang, Xuerong Yan, Zijie Chen, Ziyi Zhang, Ning Zhang, Aihemaitijiang Ailikaiti, Yiming Chen, Quanrui Yue, Yu Guo, Liaobin Chen, Hui Wang
    Signal Transduction and Targeted Therapy.2026;[Epub]     CrossRef
  • Protective potential of minimally processed, plant-derived foods against steatotic liver disease in early adulthood
    Yasmina Tashkent, Jocelyn M. Choo, Steven L. Taylor, Therese A. O'Sullivan, Dujinthan Jayabalan, Sophie J. Miller, Richard Woodman, Luis Calzadilla-Bertot, Oyekoya T. Ayonrinde, Lawrence J. Beilin, Trevor A. Mori, John K. Olynyk, Alan J. Wigg, Kate R. Mul
    Clinical Nutrition ESPEN.2026; 73: 102987.     CrossRef
  • Diagnosis and management of metabolic dysfunction-associated steatohepatitis in patients with chronic hepatitis B infection
    Talal K Bhatti, Joseph K Lim
    World Journal of Gastroenterology.2026;[Epub]     CrossRef
  • Lianhe Xiaozhi ointment ameliorates metabolic dysfunction-associated steatotic liver disease via peroxisome proliferator-activated receptor alpha pathway activation
    Li-Juan Nie, Gao-Xiang Wang, Xin-Yi Yang, Jing Sun, Yu-Tian Cao, Yan Lou, Yi-Fan Lu, Jiang-Yi Yu, Xi-Qiao Zhou
    World Journal of Gastroenterology.2026;[Epub]     CrossRef
  • Increased Cardiovascular and Cerebrovascular Events in Patients With Lean vs Non-lean MASLD: A Multicenter Analysis
    Omar Al Ta'ani, Yahya Alhalalmeh, Mohammad Alabdallat, Abdallah Naser, Saqr Alsakarneh, Saleh Saleh, Pojsakorn Danpanichkul, Dushyant Dahiya Singh, Basile Njei, Nikki Duong
    Clinical and Translational Gastroenterology.2026; 17(4): e00974.     CrossRef
  • A transdisciplinary framework for managing metabolic dysfunction associated steatotic liver disease
    Sania Kouser, Sanketh V. Sharma, Arun Bhanu, Subrahmanya Kumar Kukkupuni, Chethala N. Vishnuprasad
    Frontiers in Pharmacology.2026;[Epub]     CrossRef
  • Lysophosphatidylethanolamine Degradation Associated with Upregulation of Pnpla6/7 in a Murine Model of Metabolic Dysfunction-Associated Steatohepatitis
    Nao Inoue, Hsin-Jung Ho, Siddabasave Gowda B. Gowda, Miki Eguchi, Minato Masamura-Takeuchi, Hitoshi Chiba, Shu-Ping Hui
    International Journal of Molecular Sciences.2026; 27(4): 1869.     CrossRef
  • Predicting non-alcoholic fatty liver disease (NAFLD) using machine learning algorithms: Evidence from a large-scale community cohort in Taiwan
    Tzu-Chun Lin, Yu-Ju Wei, Po-Cheng Liang, Pei-Chien Tsai, Yi-Hung Lin, Meng-Hsuan Hsieh, Tyng-Yuan Jang, Chih-Wen Wang, Ming-Yen Hsieh, Zu-Yau Lin, Ming-Lun Yeh, Jee-Fu Huang, Chung-Feng Huang, Wan-Long Chuang, Ming-Lung Yu, Chia-Yen Dai, Hon-Yi Shi
    BioScience Trends.2026; 20(1): 80.     CrossRef
  • Dynamic FIB-4 Score Changes and HCC Risk in Patients with MASLD and Elevated Liver Enzymes: A Nationwide Cohort Study
    Yee Hui Yeo, Hsiu J. Ho, Tsai-Wei Huang, Teng-Yu Lee, Ju Dong Yang, George Cholankeril, Chien-Jen Chen, Hawi-I. Yang, Chuen-Fei Chen, Hung-Chuen Chang, Chun-Ying Wu
    Liver Cancer.2026; : 1.     CrossRef
  • Diacerein improves liver fibrosis, steatosis, and atherosclerosis in ApoE knockout mice
    Jie-Eun Lee, Isom Jin, Jung-Jae Lee, Jisu Jung, Jee-In Lee, Bo-Rahm Kim, Tae Jung Oh, Yun Kyung Lee, Sung Hee Choi
    Journal of Molecular Medicine.2026;[Epub]     CrossRef
  • Irregular meal timing and cardiometabolic risk clustering in MASLD: A case-control study
    Enrico Sguazzini, Giuseppe Colucci, Andrea Melissa Martínez, María Elena Plata Alvarado, Maria Conception Vallecillo, Wilber Pereira, Marlon Gaitan, Pietro Lampertico
    Clinics and Research in Hepatology and Gastroenterology.2026; 50(4): 102807.     CrossRef
  • Circulating Liver‐Derived and CD36+ Extracellular Vesicles Correlate With Ectopic Liver Fat and Markers of Fibrosis in Metabolic Dysfunction‐Associated Steatotic Liver Disease and Decrease During Weight Loss Intervention
    Maiken Mellergaard, Anders Askeland, Rikke Wehner Rasmussen, Katja Lund Cliff, Morten Hjuler Nielsen, Rikke Bülow Eschen, Gunna Christiansen, Peter Vestergaard, Jens Brøndum Frøkjær, Aase Handberg
    Journal of Extracellular Vesicles.2026;[Epub]     CrossRef
  • Multimodal assessment of hepatic steatosis heterogeneity: segmental MRI-PDFF and ultrasound attenuation coefficient measurement
    M.M. Zhaivoronok, N.V. Deresh, I. Sporea, O.B. Dynnyk, S.V. Feysa, O.A. Pushkarenko, O.A. Fedusenko, O.V. Shcherbina, N.M. Kobyliak
    INTERNATIONAL JOURNAL OF ENDOCRINOLOGY (Ukraine).2026; 22(2): 103.     CrossRef
  • The correlation between the trajectory of plasma atherosclerosis-inducing index in the examination population and the risk of developing metabolic dysfunction-associated steatotic liver disease
    Yongxin Li, Changying Zhao, Jun Wang, Tao Shi
    Frontiers in Endocrinology.2026;[Epub]     CrossRef
  • Electroacupuncture activates the TET1/PPARα pathway to protect mitochondrial function in MASLD
    Shurui Yang, Yiwen Li, Bowen Lu, Congcong Cheng, Yayuan Wang, Li Chen
    Journal of Inflammation.2026;[Epub]     CrossRef
  • Exposure to Environmental Pollutants and Nonalcoholic Fatty Liver Disease: A Cross‐Sectional Study
    Ying Zhang, Han‐Xu Zhu, Feng Zhang, Chao Cui, Yu‐Chen Fan, Shuai Gao, Kai Wang
    The FASEB Journal.2026;[Epub]     CrossRef
  • Cognitive-Enhancing Effects of Bioactive Compounds and Traditional Herbal Medicines in Elderly Patients with Metabolic Syndrome
    Pouria Sefidmooye Azar, Shiva Akhlaghi, Zia Shariat-Madar, Fakhri Mahdi
    Biomolecules.2026; 16(4): 535.     CrossRef
  • The HepG2 Cell Line as a Model for Studying Metabolic Dysfunction-Associated Steatotic Liver Disease
    Anna Kotlyarova, Aleksandra Iskrina, Stanislav Kotlyarov
    International Journal of Molecular Sciences.2026; 27(8): 3399.     CrossRef
  • Metabolic Dysfunction-Associated Steatotic Liver Disease and Atherosclerotic Cardiovascular Disease: Shared Pathophysiology, Biomarkers, and Emerging Therapeutic Strategies
    Madison S. Drogy, Shenelle T. Minto, William H. Frishman
    Cardiology in Review.2026;[Epub]     CrossRef
  • Critical role of interleukin-33 in pathogenesis and progression of metabolic dysfunction-associated steatotic liver disease
    Chunmei Ran, Xiaoyan Gao, Yongqin Zhou, Chibing Dai
    Frontiers in Medicine.2026;[Epub]     CrossRef
  • Metabolic dysfunction associated steatotic liver disease: mechanisms, diagnosis, and management in adults
    Tina Reinson, Josh Bilson, Caroline Childs, Ryan M Buchanan, Giovanni Targher, Christopher D Byrne
    BMJ Medicine.2026; 5(1): e002038.     CrossRef
  • Role of the NF-κB signaling pathway in vascular endothelial cell injury associated with metabolic dysfunction-associated steatotic liver disease under hypoxia
    Jingxuan Zhang, Chenguang Zhang, Chao Yang, Yongjun Miao, Xiaomeng Wei, Zijian Zhang, Zihan Shen, Guodan Bao
    Biochemical and Biophysical Research Communications.2026; 817: 153710.     CrossRef
  • Crocin II alleviates metabolic dysfunction-associated steatotic liver disease by enhancing autophagic degradation of ANGPTL8
    Rongtian Zhang, Kongdong Li, Ziting Zhao, Xintong Jiang, Rumeng Zhang, Chang Liu, Wenxiang Zhang, Siyu Chen
    Targetome.2026;[Epub]     CrossRef
  • Cost-Effectiveness of Blood-Based Fibrosis Screening in High-Risk Metabolic Liver Diseases With Emerging Therapies
    Wanyi Chen, Stephanie T. Chang, Ramsey C. Cheung, Donald B. Chalfin, Kinpritma Sangha, Szu-Yu Zoe Kao, Artem T. Boltyenkov
    Gastro Hep Advances.2026; 5(5): 100923.     CrossRef
  • Association between the visceral fat area-to-skeletal muscle mass ratio and the severity of hepatic steatosis and fibrosis among young and middle-aged adults with MASLD: a cross-sectional study
    Congfang Guo, Yudong Rong, Lili Wang, Yuting Bai, Yirui Guo, Fenghua Guo, Li Zhang, Peirong Bai, Minying Zhang, Xin Li
    European Journal of Medical Research.2026;[Epub]     CrossRef
  • Discovery of Active Compounds in Qigui Jiangzhi Formula for Metabolic Dysfunction‐Associated Steatotic Liver Disease by a Multidimensional Phenotypic Analysis
    Xianghao Xu, Fanxing Zhou, Zhe Wu, Yi Zhou, Yanying Zhang, Miao Xu, Xudong Xing, Ping Li, Guangji Wang, Hua Yang
    Phytochemical Analysis.2026;[Epub]     CrossRef
  • TyG-WHtR predicts incident type 2 diabetes mellitus in NAFLD: a 12-year prospective cohort study
    Nan’nan Chen, Jiang Li, Gang Li, Faming Zhao
    Frontiers in Endocrinology.2026;[Epub]     CrossRef
  • Ergothioneine alleviates hepatic steatosis by modulating PCYT2 to restore the phosphatidylethanolamine-ACOT8 homeostasis
    Rongyi Ye, Yihan Wang, Kebo Wang, Nan Huang, Guo Liu, Dexin Gao, Xinru Li, Mengxue Yang, Jing Wang, Chen Chen
    Phytomedicine.2026; 158: 158238.     CrossRef
  • Benzo[a]pyrene induces non-alcoholic fatty liver disease by exacerbating hepatic senescence and disrupting gut-liver axis in zebrafish
    Yang Shu, Kaiwen Hu, Chenxin Gong, Yingying Yu, Conghui Shan, Xinrui Ge, Haibin Yu, Wei Shi, Guangxu Liu
    Journal of Hazardous Materials.2026; 512: 142365.     CrossRef
  • Expert panel perspectives on improving the diagnosis and management of metabolic dysfunction-associated steatohepatitis in Denmark
    Aleksander Krag, Jens Søndergaard, Mette Theil, Mette Lehmann Andersen, Frede Lyck, Lone McColaugh, Katrine Prier Lindvig, Lise Lotte Gluud
    Scandinavian Journal of Gastroenterology.2026; : 1.     CrossRef
  • Regression of Metabolic Dysfunction–Associated Steatotic Liver Disease in Older Adults: Short- and Long-Term Prediction Models in the NHIS-Senior and UK Biobank Cohorts
    Taeho Kwak, Eun Seok Kang, Jihun Song, Batuhan Gökbulut, Seohui Jang, Minjeong Kang, Jeongin Lee, Seokjin Kong, Yihyun Kim, Jin-Hyun Park, Sangwook Cheon, Jinhyeok Choi, Jaewon Khil, Hye Jun Kim, Bilguuntuguldur Samaindagva, Hwamin Lee, Yohwan Lim, Seogso
    Nutrition, Metabolism and Cardiovascular Diseases.2026; : 104816.     CrossRef
  • The Liver-brain Axis: A Three-stage Model Linking MASLD to Cognitive Impairment and Dementia
    Lijuan Nie, Yinglian Zhao, Wanbin Liu, Xiqiao Zhou, Qingrong Xia
    Journal of Molecular Neuroscience.2026;[Epub]     CrossRef
  • Evaluation of Sarcopenic Obesity in Patients with MASLD
    Niki G. Mourelatou, Triada Bali, Magdalini Adamantou, Lampros Chrysavgis, Christos Chologkitas, Margarita Sarri, Dimitra Pavlopoulou, Georgios Schinas, Theodoros Androutsakos, Georgia Sypsa, Dimitrios S. Karagiannakis, George Papatheodoridis, Nikolaos Ten
    Medical Sciences.2026; 14(2): 257.     CrossRef
  • Attenuation of diet-induced hepatic steatosis by capric acid-rich MLM structured lipids in an obese mouse model
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    The Journal of Nutritional Biochemistry.2026; 157: 110419.     CrossRef
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    Jens Bjelke Kristensen, Jacob Nøhr-Meldgaard, Susanne E. Pors, Jenny Norlin, Sanne S. Veidal, Kristian Moss Bendtsen, Kristoffer Niss, Maja W. Andersen, Lea M. Harder, Mathilde Teilmann Dalhoff, Martin Rønn Madsen, Kristoffer Voldum-Clausen, Markus Latta,
    American Journal of Physiology-Gastrointestinal and Liver Physiology.2026; 330(6): G659.     CrossRef
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    Karolina Kornatowska, Szymon Kopciał, Mateusz Wiekiera, Adrianna Wiekiera, Paweł Budzik, Mateusz Tyniec, Kamal Morshed
    Gastroenterology Insights.2026; 17(2): 33.     CrossRef
  • Arachidonoyl-taurine is elevated in human MASLD and protects against hepatic steatosis and inflammation in preclinical models
    Katharina B. Kuentzel, Samuel A.J. Trammell, Anna S. Hassing, Ivan Bradić, Michelle Damgaard, Emma B. Fals, Katja T. Michler, Matthew Dooley, Jens C.B. Jacobsen, Malte P. Suppli, Mikkel P. Werge, Cameron J. Mitchell, Nicolai J. Wewer Albrechtsen, Lise L.
    Journal of Hepatology.2026;[Epub]     CrossRef
  • Microbial Metabolomic Signatures Reveal Underlying Phenotypic Divergence in Lean and Obese Mice with MASH under Identical Dietary Stress
    Tanuja Mohanty, Anil Kumar Baidya, Palok Aich
    Journal of the American Society for Mass Spectrometry.2026;[Epub]     CrossRef
  • Multi-modal machine learning highlights recipient genetic and clinical factors as primary drivers of post-transplant MASLD: A two-center study
    Soumita Ghosh, Khairunnadiya Prayitno, Saba Maleki, Amirhossein Azhie, Lila González Hodár, Bima J. Hasjim, Shlok Panchal, Jason M. Vanatta, Quynh T. Tran, Sanjaya K. Satapathy, Yaron Rotman, Mamatha Bhat
    Liver Transplantation.2026;[Epub]     CrossRef
  • Nitric oxide pathway: Emerging therapeutic strategies for MASLD
    Yanling Zhang, Ying Zhang, Hongjin Chen, Fangfang Qi
    Pathology - Research and Practice.2026; 284: 156516.     CrossRef
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    Juhui Jin, Morgan Sotzen, Daphne K. Weikart, Tai‐Jung Lee, Kumble Sandeep Prabhu, Joshua D. Lambert
    Molecular Nutrition & Food Research.2026;[Epub]     CrossRef
  • Extracellular Vesicle from Chlorella vulgaris Alleviates Hepatic Fibrosis in a Mouse Model of Metabolic Dysfunction-Associated Steatotic Liver Disease Through Modulation of Inflammatory Signaling
    Hinata Harada, Yusuke Ohsaki, Afifah Zahra Agista, Hsin-Jung Ho, Takuo Hirose, Kotaro Yamada, Mutsumi Furukawa, Tomonori Nochi, Wan-Chun Chiu, Ya-Ling Chen, Chiu-Li Yeh, Suh-Ching Yang, Takefumi Mori, Hitoshi Shirakawa
    International Journal of Molecular Sciences.2026; 27(9): 3735.     CrossRef
  • Metabolic dysfunction-associated steatotic liver disease: pathogenesis and novel treatment options
    Ruizhe Ren, Xiao Liang, Xiyang Wei
    Molecular Biomedicine.2026;[Epub]     CrossRef
  • Effectiveness of sodium–glucose cotransporter 2 inhibitors in patients with metabolic dysfunction-associated steatotic liver disease: systematic review and meta-analysis of randomized controlled trials
    Milena Ramos Tomé, Jingying Elena Chen, Alana Vitória Santos de Jesus, Wellgner Fernandes Oliveira Amador, Gustavo Procópio Silva, Igor Boechat Silveira, Arthur Victor de Holanda Sampaio, Guilherme Grossi Lopes Cançado
    European Journal of Gastroenterology & Hepatology.2026;[Epub]     CrossRef
  • La endocrinología en el epicentro de la esteatosis hepática metabólica
    Miguel Ángel Rubio-Herrera, Javier Escalada San Martín
    Endocrinología, Diabetes y Nutrición.2026; 73(6): 501847.     CrossRef
  • Impact of Volatile Organic Compound Mixtures on Cardiovascular Health in Adults With Metabolic Dysfunction–Associated Fatty Liver Disease: A US Population Study
    Qingping Wu, Meiling Jin, Shan Liu, Yue Wu, Tarek Alshaal
    Indoor Air.2026;[Epub]     CrossRef
  • Endocrinology at the epicenter of metabolic associated steatotic liver disease
    Miguel Ángel Rubio-Herrera, Javier Escalada San Martín
    Endocrinología, Diabetes y Nutrición (English ed.).2026; 73(6): 501847.     CrossRef
  • Hepatoprotective effects of the branched-chain fatty acids 12-methylmyristic and 13-methylmyristic against palmitate-induced lipotoxicity
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    Biomedicine & Pharmacotherapy.2026; 201: 119687.     CrossRef
  • Alcohol intake reprograms hepatic immune-metabolic circuits to exacerbate murine atherosclerosis and human cardiovascular risk
    Constanze Hoebinger, Georg Semmler, Oleksandr Petrenko, Dragana Rajcic, Dorothea Katharina Hoffelner, Tereza Duckova, Taras Baranovskyi, Laura Goederle, My Phung Khuu, Christoph Reinhardt, Petra Pjevac, Joana Séneca, Kamil Mieczkowski, Katharina Burger, I
    JHEP Reports.2026; : 101932.     CrossRef
  • The association between six heavy metal levels and the risk of liver fibrosis in women without gestational diabetes mellitus
    Juan Yu, Li Wang, Shu-lan Zhu, Min Xiao, Hai-xing Huang, Yan-hong Shao, Qi-chen Bao, Miao-miao Ma, Ying-ying Chen
    The American Journal of the Medical Sciences.2026;[Epub]     CrossRef
  • The mineralocorticoid receptor and its antagonist finerenone regulate hepatic lipid accumulation via the AMPK/SREBP1/FASN signaling
    Shanpan Fu, Mingyan Zhang, Kai Wang, Shuai Huang, Yuemei Xi, Jiayu Chen, De Xie, Qian Zhang, Wanling Que, Xueling Ye, Shuyi Chen, Yayan Liu, Mengni Wu, Liushuang Xu, Cuiying Ye, Tetsuya Yamamoto, Hidenori Koyama, Changgui Li, Yanhui Wu, Jidong Cheng
    Molecular and Cellular Endocrinology.2026; 620: 112845.     CrossRef
  • Emerging metabolic hormone therapeutics for metabolic dysfunction-associated steatohepatitis: incretin-based drugs, fibroblast growth factor analogs, and liver-targeting strategies
    Sukwoo Han, Jaehee Shin, Jae Cheon Kim, Dong Hee Na
    Journal of Pharmaceutical Investigation.2026;[Epub]     CrossRef
  • Walking the VLDL tightrope in cardiometabolic diseases
    Mindy Kim, Ze Zheng
    Trends in Endocrinology & Metabolism.2025; 36(3): 278.     CrossRef
  • Evolving Global Etiology of Hepatocellular Carcinoma (HCC): Insights and Trends for 2024
    Abraham Koshy
    Journal of Clinical and Experimental Hepatology.2025; 15(1): 102406.     CrossRef
  • Appendicular skeletal muscle mass is associated with metabolic dysfunction-associated steatotic liver disease severity in young men: a cross-sectional and longitudinal study
    Jaejun Lee, Jinson So, Chang In Han, Hyun Yang, Pil Soo Sung, Si Hyun Bae, Do Seon Song
    Hepatology International.2025; 19(1): 181.     CrossRef
  • Statin Therapy is Associated With Lower Risk of Mortality Among Liver Transplant Candidates With Metabolic Dysfunction-associated Steatohepatitis
    Katherine M. Cooper, Ami K. Patel, Christopher A. Zammitti, Ellen Murchie, Alessandro Colletta, Deepika Devuni
    Journal of Clinical and Experimental Hepatology.2025; 15(2): 102427.     CrossRef
  • The Changing Demographics and Epidemiology of Hepatocellular Carcinoma
    Rushabh Gujarathi, Jeremy A. Klein, Chih-Yi Liao, Anjana Pillai
    Clinics in Liver Disease.2025; 29(1): 1.     CrossRef
  • Lipotoxicity-driven metabolic dysfunction-associated steatotic liver disease (MASLD)
    Santiago Iturbe-Rey, Claudia Maccali, Marco Arrese, Patricia Aspichueta, Claudia P. Oliveira, Rui E. Castro, Ainhoa Lapitz, Laura Izquierdo-Sanchez, Luis Bujanda, Maria J. Perugorria, Jesus M. Banales, Pedro M. Rodrigues
    Atherosclerosis.2025; 400: 119053.     CrossRef
  • The impact of resistance training in patients diagnosed with metabolic dysfunction-associated steatotic liver disease: a systematic review
    Daniele Gorski Medeiros, Luis Fernando Ferreira, Jessica da Silva Lamp, Luis Henrique Telles da Rosa
    European Journal of Gastroenterology & Hepatology.2025; 37(2): 129.     CrossRef
  • Meta‐Analysis: Global Prevalence and Mortality of Cirrhosis in Metabolic Dysfunction‐Associated Steatotic Liver Disease
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    Alimentary Pharmacology & Therapeutics.2025; 61(3): 433.     CrossRef
  • Interdisciplinary perspectives on the co-management of metabolic dysfunction-associated steatotic liver disease and coronary artery disease
    Jacob J Gries, Jeffrey V Lazarus, Paul N Brennan, Mohammad S Siddiqui, Giovanni Targher, Chim C Lang, Salim S Virani, Carl J Lavie, Scott Isaacs, Juan Pablo Arab, Kenneth Cusi, Chayakrit Krittanawong
    The Lancet Gastroenterology & Hepatology.2025; 10(1): 82.     CrossRef
  • Cardiovascular-Liver-Metabolic Health: Recommendations in Screening, Diagnosis, and Management of Metabolic Dysfunction-Associated Steatotic Liver Disease in Cardiovascular Disease via Modified Delphi Approach
    Nicholas W.S. Chew, Anurag Mehta, Rachel Sze Jen Goh, Audrey Zhang, Yiming Chen, Bryan Chong, Han Shi Jocelyn Chew, Asim Shabbir, Adrian Brown, Georgios K. Dimitriadis, Daniel Q. Huang, Roger Foo, Carel W. le Roux, Gemma A. Figtree, Marat Fudim, Ambarish
    Circulation.2025; 151(1): 98.     CrossRef
  • The evolving role of liver biopsy: Current applications and future prospects
    Purva Gopal, Xiaobang Hu, Marie E. Robert, Xuchen Zhang
    Hepatology Communications.2025;[Epub]     CrossRef
  • Associations of the Intake of Individual and Multiple Flavonoids with Metabolic Dysfunction Associated Steatotic Liver Disease in the United States
    Chen Wang, Mengchu Li, Jiali Zhang, Hongguang Li, Yue Li, Siyu Huang, Huilian Zhu, Zhaoyan Liu
    Nutrients.2025; 17(2): 205.     CrossRef
  • Performance of Noninvasive Indices for Discrimination of Metabolic Dysfunction-Associated Steatotic Liver Disease in Young Adults
    Jaejun Lee, Chang In Han, Dong Yeup Lee, Pil Soo Sung, Si Hyun Bae, Hyun Yang
    Gut and Liver.2025; 19(1): 116.     CrossRef
  • Comparison of Referral Rates and Costs Using Fibrosis-4 and Enhanced Liver Fibrosis (ELF) Testing Strategies for Initial Evaluation of Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) in a Veteran Population
    Samrat Yeramaneni, Stephanie T Chang, Ramsey C Cheung, Donald B Chalfin, Kinpritma Sangha, H Roma Levy, Artem T Boltyenkov
    The Journal of Applied Laboratory Medicine.2025; 10(3): 593.     CrossRef
  • Meta‐Analysis of Placebo‐Treated Patients: Dropout Rates From Treatment in MASH Randomised Controlled Trials
    Matheus Souza, Marcio J. M. Amaral, Luan C. V. Lima, Cristiane Alves Villela‐Nogueira
    Alimentary Pharmacology & Therapeutics.2025; 61(5): 776.     CrossRef
  • PBCS-ConvNeXt: Convolutional Network-Based Automatic Diagnosis of Non-alcoholic Fatty Liver in Abdominal Ultrasound Images
    Shang-Yu Chiang, You-Wei Wang, Pei-Yuan Su, Yuan-Yen Chang, Hsu-Heng Yen, Ruey-Feng Chang
    Journal of Imaging Informatics in Medicine.2025; 38(5): 2878.     CrossRef
  • A complement to epigenetics in metabolic dysfunction-associated steatotic liver disease: Editorial on “DNA methylome analysis reveals epigenetic alteration of complement genes in advanced metabolic dysfunction-associated steatotic liver disease”
    Johanna K. DiStefano, Glenn S. Gerhard
    Clinical and Molecular Hepatology.2025; 31(1): 297.     CrossRef
  • Association of prebiotic/probiotic intake with MASLD: evidence from NHANES and randomized controlled trials in the context of prediction, prevention, and a personalized medicine framework
    Senlin Wang, Ruimin Zhang, Peisen Guo, Huawu Yang, Yanjun Liu, Hongmei Zhu
    EPMA Journal.2025; 16(1): 183.     CrossRef
  • Insights into the results of Resmetirom trials: Can a thyroid hormone receptor agonist be the holy grail of MASH therapy?
    Konstantinos Arvanitakis, Theocharis Koufakis, Evangelos Cholongitas, Sven Francque, Georgios Germanidis
    Pharmacology & Therapeutics.2025; 268: 108811.     CrossRef
  • Association between the Fatty Liver Index, Metabolic Dysfunction-Associated Steatotic Liver Disease, and the Risk of Kidney Stones
    Fan Zhang, Wenjian Li
    Kidney and Blood Pressure Research.2025; 50(1): 115.     CrossRef
  • Psychosocial risks in metabolic dysfunction-associated steatotic liver disease
    Hanne Åström, Christine Takami Lageborn, Hannes Hagström
    Expert Review of Gastroenterology & Hepatology.2025; 19(3): 273.     CrossRef
  • Glucagon like peptide-1 receptor agonists as a promising therapeutic option of metabolic dysfunction associated steatotic liver disease and obesity: hitting two targets with one shot
    Eda Kaya, Wing-Kin Syn, Paul Manka
    Current Opinion in Gastroenterology.2025; 41(3): 104.     CrossRef
  • Metabolic dysfunction-associated steatotic liver disease (MASLD): a systemic disease with a variable natural history and challenging management
    Luigi Elio Adinolfi, Aldo Marrone, Luca Rinaldi, Riccardo Nevola, Antonio Izzi, Ferdinando Carlo Sasso
    Exploration of Medicine.2025;[Epub]     CrossRef
  • Analyzing MASLD interventional clinical trial registration based on the ClinicalTrials.gov database
    Hui Du, Jihan Huang, Youhua Wang, Chunyan Wang, Yiqun Wang, Luming Hou, Yali Li, Ying Li, Qianmin Su
    BMC Gastroenterology.2025;[Epub]     CrossRef
  • The relationship between the ratio of non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol (NHHR) and both MASLD and advanced liver fibrosis: evidence from NHANES 2017–2020
    Juyi Li, Chunjia Kou, Yuwei Chai, Yuchen Li, Xue Liu, Li Zhang, Haiqing Zhang
    Frontiers in Nutrition.2025;[Epub]     CrossRef
  • Therapeutic Potential of GLP-1 Receptor Agonists in Metabolic Associated Steatotic Liver Disease
    Klaudia Nowak, Krzysztof Łupina, Anna Romac, Aleksandra Kalisz, Łucja Ilkiewicz, Jakub Janczura
    Annals of Pharmacotherapy.2025; 59(10): 928.     CrossRef
  • miR-125b-5p regulates FFA-induced hepatic steatosis in L02 cells by targeting estrogen-related receptor alpha
    Fen Gao, Yanhua Ma, Chun Yu, Qianchen Duan
    Gene.2025; 959: 149419.     CrossRef
  • Epidemiology of metabolic dysfunction-associated steatotic liver disease
    Zobair M. Younossi, Markos Kalligeros, Linda Henry
    Clinical and Molecular Hepatology.2025; 31(Suppl): S32.     CrossRef
  • Unraveling the molecular mechanisms of Fufangduzhong formula in alleviating high-fat diet-induced non-alcoholic fatty liver disease in mice
    Yu Mou, Yao Tang, Xiuyan Zheng, Xiang Liu, Xuemei Wu, Hongji Wang, Jie Zeng, Qing Rao, Yaacov Ben-David, Yanmei Li, Lei Huang
    Frontiers in Pharmacology.2025;[Epub]     CrossRef
  • Steatotic Liver Disease in Younger Adults is Associated With Altered Gut Microbiology
    Yasmina Tashkent, Jocelyn M. Choo, Alyson Richard, Zhengyi Wang, Luis Calzadilla‐Bertot, Egi Vasil, Sophie Miller, Steven L. Taylor, Kerry L. Ivey, Richard Woodman, Brendan Adler, Oyekoya T. Ayonrinde, John K. Olynyk, Lawrence J. Beilin, Trevor A. Mori, A
    Liver International.2025;[Epub]     CrossRef
  • Low HDL cholesterol levels in women and hypertriglyceridemia in men: predictors of MASLD onset in individuals without steatosis
    Tsubasa Tsutsumi, Takumi Kawaguchi, Hideki Fujii, Yoshihiro Kamada, Yuichiro Suzuki, Koji Sawada, Miwa Tatsuta, Tatsuji Maeshiro, Hiroshi Tobita, Takemi Akahane, Chitomi Hasebe, Miwa Kawanaka, Takaomi Kessoku, Yuichiro Eguchi, Hayashi Syokita, Atsushi Nak
    Journal of Gastroenterology.2025; 60(7): 891.     CrossRef
  • The emerging role of E3 ubiquitin ligases and deubiquitinases in metabolic dysfunction-associated steatotic liver disease
    Yu Zhang, Jiahui Yang, Jiali Min, Shan Huang, Yuchen Li, Shanshan Liu
    Journal of Translational Medicine.2025;[Epub]     CrossRef
  • MASLD: Prevalence, Mechanisms, and Sex-Based Therapies in Postmenopausal Women
    Ilaria Milani, Marianna Chinucci, Frida Leonetti, Danila Capoccia
    Biomedicines.2025; 13(4): 855.     CrossRef
  • C-C motif chemokines ligand 7 contributes to metabolic dysfunction-associated steatotic liver disease by enabling redox-sensitive induction of hypermethylated in cancer 1
    Xinyue Sun, Jinge Wu, Huiqian Lv, Ben Wang, Xuelian Chen, Wenjing Ren, Xiulian Miao, Yan Guo, Xiaocen Kong, Huihui Xu, Zeqing Bao, Yong Xu, Zilong Li
    Metabolism.2025; 168: 156242.     CrossRef
  • Neutrophils in MASLD and MASH
    Sanjeeb Shrestha, Jae-Han Jeon, Chang-Won Hong
    BMB Reports.2025; 58(3): 116.     CrossRef
  • ROS Signaling Controls Lipid Accumulation in HepG2 Cells Driven by Doxorubicin-Induced Senescence
    Chawon Yun, Seung Jun Noh, Hamed Kazemi Zahrani, Sou Hyun Kim, Young-Suk Jung
    Drug Targets and Therapeutics.2025; 4(1): 1.     CrossRef
  • Construction and evaluation of a diagnostic model for metabolic dysfunction-associated steatotic liver disease based on advanced glycation end products and their receptors
    Xiao Cao, Xiaohua Xiao, Peipei Jiang, Nian Fu
    Frontiers in Medicine.2025;[Epub]     CrossRef
  • Clinical Insights on Resmetirom
    Eda Kaya, Yusuf Yilmaz, Naim Alkhouri
    Journal of Clinical Gastroenterology.2025; 59(5): 412.     CrossRef
  • Ernährung und körperliches Training bei Lebererkrankungen
    Thomas-Matthias Scherzer, Bettina Knabl, Benedikt Mehl
    Journal für Gastroenterologische und Hepatologische Erkrankungen.2025; 23(1): 12.     CrossRef
  • Are glyphosate or glyphosate-based herbicides linked to metabolic dysfunction-associated steatotic liver disease (MASLD)? The weight of current evidence
    Luana Riechelmann-Casarin, Leticia Cardoso Valente, Rosemari Otton, Luís Fernando Barbisan, Guilherme Ribeiro Romualdo
    Environmental Toxicology and Pharmacology.2025; 116: 104705.     CrossRef
  • Sex differences in the mediation of the MASLD - Depression association by fat distribution in U.S. adults
    Changhuai He, Liuxin Zhou, Tianming Gao, Runmin Cao, Chuanqi Cai, Guoqing Jiang
    Acta Psychologica.2025; 256: 105041.     CrossRef
  • Association of biological aging and the prevalence of nonalcoholic fatty liver disease: a population-based study
    Gang Liu, Qingsong Mao, Xinling Tian, Chenwei Zhang, Yukai Zhang, Jiarong He, Yuzhe Kong
    BMC Gastroenterology.2025;[Epub]     CrossRef
  • Association Between Uric Acid to HDL-C Ratio and Metabolic Dysfunction-Associated Steatotic Liver Disease in Type 2 Diabetes Mellitus: A Cross-Sectional Study
    Xiangyun Zhu, Han Yin, Jing Han, Xiaoyan Zhang, Qing Han, Weixia Sun, Yijun Liu, Wenxuan Tao, Xinliang Liu, Guofeng Wang, Ling Li
    Diabetes, Metabolic Syndrome and Obesity.2025; Volume 18: 1459.     CrossRef
  • Association of PNPLA3 Genetic Polymorphism with Non-Alcoholic Fatty Liver Disease in Sikkim: A Pilot Study
    Vaishnavi Singh, Arundhati Bag, Bidita Khandelwal, Debarghya Sutradhar
    National Academy Science Letters.2025;[Epub]     CrossRef
  • Increased Mortality Among Lean Versus Non‐Lean Adults With MASLD: A Multicenter Study
    Leith Ghani, Majd B. Aboona, Claire S. Faulkner, Pooja Rangan, Moises Nevah Rubin, Ma Ai Thanda Han, Michael B. Fallon, Vincent L. Chen, Karn Wijarnpreecha
    Journal of Gastroenterology and Hepatology.2025; 40(8): 1919.     CrossRef
  • A potential herbal component for the future treatment of fatty liver disease: Geniposide from gardenia
    Qinyao Zhang, Ziyan Li, Lina Wang
    Frontiers in Pharmacology.2025;[Epub]     CrossRef
  • In vitro antioxidant effects and in vivo hepatoprotective effects of Osbeckia octandra, Vernonia cinerea and Atalantia ceylanica on a high fat diet induced metabolic dysfunction-associated steatotic liver disease mouse model
    Anuththara Upamali Abeykoon, Madhavi Priyanka Paranagama, Kavindra Kumara Wijesundera, Onela Canith Pathirana, Thilini Anupama Mahakapuge, Jayantha Rajapakse
    BMC Complementary Medicine and Therapies.2025;[Epub]     CrossRef
  • Pruritus and Fatigue in Patients With Metabolic Dysfunction-Associated Steatotic Liver Disease: A Study of Turkish Patients From the Global NASH/MASH Registry
    Yusuf Yilmaz, Caglayan Keklikkiran, Andrei Racila, Maria Stepanova, Zobair M. Younossi
    Clinical and Translational Gastroenterology.2025; 16(6): e00844.     CrossRef
  • Omega-3 polyunsaturated fatty acids and nonalcoholic fatty liver disease in adults: A meta-analysis of randomized controlled trials
    Su Jin Kim, Su Hwan Cho, Jae Moon Yun
    Clinical Nutrition.2025; 50: 164.     CrossRef
  • Hyperuricemia—Especially “Metabolic Hyperuricemia”—Is Independently Associated with a Higher Risk of Steatotic Liver Disease
    Janis Timsans, Jenni Kauppi, Vappu Rantalaiho, Anne Kerola, Kia Hakkarainen, Mika Paldanius, Hannu Kautiainen, Markku Kauppi
    Metabolites.2025; 15(6): 356.     CrossRef
  • Gut microbiota modulation by Traditional Chinese Medicine: a translational strategy for metabolic dysfunction-associated steatotic liver disease
    Ting Zhou, Ziwen Jin, Rilei Jiang, Weiwei Li
    Frontiers in Pharmacology.2025;[Epub]     CrossRef
  • Oleocanthalic acid improves MASH features via a NOX1-dependent mechanism
    Yahima Frion-Herrera, Ilaria Zanotto, Martina Colognesi, Anna Signor, Doretta Cuffaro, Adriana Chilin, Marco Macchia, Giovanni Marzaro, Maria Digiacomo, Daniela Gabbia, Sara De Martin
    European Journal of Pharmacology.2025; 1002: 177847.     CrossRef
  • Projected Trends in Metabolic Dysfunction–Associated Steatotic Liver Disease Mortality Through 2040
    Xinrong Zhang, Sovann Linden, Charles R. Levesley, Xinyuan He, Zhanpeng Yang, Scott D. Barnet, Ramsey Cheung, Fanpu Ji, Mindie H. Nguyen
    JAMA Network Open.2025; 8(6): e2516367.     CrossRef
  • Association of behavioral factors, liver function and NAFLD: Bayesian Mendelian randomization
    Lei Pu, Cheng Pu, Xiaoyan Zhang
    Nutrition & Metabolism.2025;[Epub]     CrossRef
  • Adding salt to foods and risk of metabolic dysfunction-associated steatotic liver disease and other chronic liver diseases
    Shunming Zhang, Zhenyu Huo, Yan Borné, Emily Sonestedt, Lu Qi
    European Journal of Nutrition.2025;[Epub]     CrossRef
  • A Gastroenterologist’s Approach to Improving Metabolic Health in MASLD
    Eyad Abdulrazzak, Imad Alabdul Razzak, Mazen Noureddin, Hirsh D. Trivedi
    Journal of Clinical Gastroenterology.2025; 59(8): 713.     CrossRef
  • Elucidating the mechanistic interplay of AMPK and Nrf2 in MASLD: A focus on dietary phytochemical modulation of lipid and redox homeostasis
    Cindy H.J. Yu, H.P. Vasantha Rupasinghe
    Biochemical and Biophysical Research Communications.2025; 777: 152300.     CrossRef
  • Association between the dietary index for gut microbiota and all-cause/cardiovascular mortality in patients with metabolic dysfunction-associated steatotic liver disease
    Wenhao Wu, Jiacheng Cheng, Zebin Hou, Qi Yan, Xiaojuan Wang, Junhua He, Yikun Zhu, Jin Li
    Diabetology & Metabolic Syndrome.2025;[Epub]     CrossRef
  • Steatosis non-invasive tests accurately predict metabolic dysfunction-associated steatotic liver disease, while fibrosis non-invasive tests fall short: Validation in U.S. adult population
    Ayesha Sualeheen, Sze-Yen Tan, Robin M. Daly, Ekavi Georgousopoulou, Gavin Abbott, Stuart K. Roberts, Jacob George, Elena S. George
    Clinics and Research in Hepatology and Gastroenterology.2025; 49(7): 102649.     CrossRef
  • A nomogram incorporating clinical and laboratory indicators for predicting metabolic dysfunction‐associated fatty liver disease in newly diagnosed type 2 diabetes patients
    Tingting Li, Yao Wang, Shengnan Zhao, Yuliang Cui, Zhenzhen Qu
    Journal of Diabetes Investigation.2025; 16(10): 1919.     CrossRef
  • Liver disease trends in the Asia-Pacific region for the next 50 years
    Shuichiro Shiina, Javkhlan Maikhuu, Qing Deng, Terguunbileg Batsaikhan, Lariza Marie Canseco, Maki Tobari, Hitoshi Maruyama, Hiroaki Nagamatsu, Diana Alcantara-Payawal, Rino Gani, Yi-Hsiang Huang, Tawesak Tanwandee, Giovanni Galati, Yoon Jun Kim
    Clinical and Molecular Hepatology.2025; 31(3): 671.     CrossRef
  • Association of APOC3 and PNPLA3 genetic polymorphism in adult Pakistani population with non-alcoholic fatty liver disease
    Muhammad Masroor, Zeba Haque, Haya Anwar, Farina Hanif, Waqas Ahmed Farooqui
    Human Gene.2025; 45: 201453.     CrossRef
  • Analysis of the Mitochondrial Dynamics in NAFLD: Drp1 as a Marker of Inflammation and Fibrosis
    Maël Padelli, Jocelyne Hamelin, Christophe Desterke, Mylène Sebagh, Raphael Saffroy, Claudio Garcia Sanchez, Audrey Coilly, Jean-Charles Duclos-Vallée, Didier Samuel, Antoinette Lemoine
    International Journal of Molecular Sciences.2025; 26(15): 7373.     CrossRef
  • Exploring the role of xanthine oxidase and aldehyde oxidase in metabolic dysfunction-associated steatotic liver disease (MASLD)
    Neha Gupta, Kavita Singh
    Journal of Molecular Histology.2025;[Epub]     CrossRef
  • Guideline-directed medical strategies for the co-management of heart failure and metabolic dysfunction-associated steatotic liver disease
    Jacob J. Gries, Bing Chen, Meena B. Bansal, Mario Rodriguez, Saleh A. Alqahtani, Paul N. Brennan, Chim C. Lang, W. H. Wilson Tang, Jeffrey V. Lazarus, Chayakrit Krittanawong
    Communications Medicine.2025;[Epub]     CrossRef
  • Liver sinusoidal endothelial cells: Central mediators of MASLD pathogenesis and sepsis susceptibility
    Yanying Wu, Wenyi Le, Huali Zhang, Yaxi Zhu
    Life Sciences.2025; 379: 123879.     CrossRef
  • The Impact of Menopausal Hormone Therapy on Liver and Biliary Tract Health
    A. O. Bueverov, N. I. Tapilskaya
    Russian Journal of Gastroenterology, Hepatology, Coloproctology.2025; 35(3): 104.     CrossRef
  • Translating Trial to Treatment: A Scoping Review of Resmetirom First Year in Real-World Use for Moderate to Advanced Fibrosis in Metabolic Dysfunction-Associated Steatohepatitis
    Kanika Vats, Mohammad Mazhar Alam
    Cureus.2025;[Epub]     CrossRef
  • Placebo Effect on Changes in Magnetic Resonance-based Endpoints in Patients With MASH: Systematic Review and Meta-analysis
    Matheus Souza, Lubna Al-Sharif, Samira M. Khalil, Ivanna Diaz
    Journal of Clinical and Experimental Hepatology.2025; 15(6): 103173.     CrossRef
  • Automated Detection of Non‐Alcoholic Fatty Liver Disease Using Histopathological Images: A Systematic Review
    Hamed Zamanian, Ahmad Shalbaf, Maryam Parvizi, Roohallah Alizadehsani, Ru‐San Tan, U. Rajendra Acharya
    WIREs Data Mining and Knowledge Discovery.2025;[Epub]     CrossRef
  • Patatin-Like Phospholipase Domain-Containing Protein 3 (PNPLA3) rs738409 Variant and Non-Alcoholic Fatty Liver Disease Risk in Vietnamese Working-Age Adults: A Case-Control Study with Metabolic Insights
    Ha Nguyen, Duong Hoang Huy Le, Thinh Nguyen, Hung Cao Dinh, Tuan Nguyen
    Clinical and Experimental Gastroenterology.2025; Volume 18: 191.     CrossRef
  • Xiaoyao San's dual efficacy in NAFLD and depression: Unraveling the mechanisms via network pharmacology and multi-omics
    Yunxiao Liu, Xiaomei Ding, Ayesha Younas, Xiaoning Sun, Xiaofen Ni, Shuanghu Wang, Jiaojian Lv, Zhiyong Li, Chuxiao Shao
    Phytomedicine.2025; 147: 157221.     CrossRef
  • Burden and trends of nonalcoholic steatohepatitis-related liver cancer in China: A population-based observational study using GBD 2021 data
    Meng-Xiang Xiang, Peng Yan, Bin Lan, Jiang-Bei Deng, Jie Tan
    Medicine.2025; 104(37): e44515.     CrossRef
  • Hepatic Insulin Resistance and Steatosis in Metabolic Dysfunction-Associated Steatotic Liver Disease: New Insights into Mechanisms and Clinical Implications
    Xuan Trong Truong, Dae Ho Lee
    Diabetes & Metabolism Journal.2025; 49(5): 964.     CrossRef
  • Sex Differences in MASLD After Age 50: Presentation, Diagnosis, and Clinical Implications
    Ilaria Milani, Maria Eugenia Parrotta, Luca Colangeli, Marianna Chinucci, Simonetta Palleschi, Barbara Rossi, Paolo Sbraccia, Alessandro Mantovani, Frida Leonetti, Valeria Guglielmi, Danila Capoccia
    Biomedicines.2025; 13(9): 2292.     CrossRef
  • The impact of the Mediterranean diet on liver steatosis and fibrosis in patients with type 2 diabetes and metabolic dysfunction-associated steatotic liver disease
    Simona Cernea, Danusia Onișor, Andrada Larisa Roiban
    Acta Marisiensis - Seria Medica.2025; 71(3): 188.     CrossRef
  • Managing MASLD Through Preventive Hepatology: Integrating Policy Reform, Public Health and Personalised Care
    Zobair M. Younossi, Vincent Wai‐Sun Wong, Emmanuel A. Tsochatzis, Laurent Castera, Michael Betel, Linda Henry, Shira Zelber Sagi
    Liver International.2025;[Epub]     CrossRef
  • Enzyme-responsive oleoylethanolamide-releasing nanomedicine for sustained liver delivery and therapeutic improvement in early-stage metabolic dysfunction-associated steatohepatitis (MASH)
    Yuanyuan Ding, Babita Shashni, Yukio Nagasaki
    Journal of Controlled Release.2025; 387: 114256.     CrossRef
  • Effect of Varying Degrees of Hepatic Impairment on the Pharmacokinetics of Ervogastat, a Diacylglycerol Acyltransferase 2 (DGAT2) Inhibitor, and Clesacostat, an Acetyl‐CoA Carboxylase (ACC) Inhibitor
    Manoli Vourvahis, Arthur J. Bergman, Adam G. Ogden, Jim Hughes, James R. Gosset, Amit S. Kalgutkar, Neeta B. Amin
    The Journal of Clinical Pharmacology.2025; 65(12): 1876.     CrossRef
  • Prevalence of metabolic dysfunction-associated fatty liver disease among health check-up attendees: A retrospective study conducted in Vietnam
    Ngan Lam Lu, Huong Tu Lam, Thong Duy Vo
    World Journal of Gastroenterology.2025;[Epub]     CrossRef
  • The pathogenesis of metabolic dysfunction-associated steatotic liver disease and nucleoside reverse transcriptase inhibitors (NRTIs) -based HIV-antiretroviral regimens: A comprehensive narrative review
    Marilize Horn, Nontobeko Gumede, Mlindeli Gamede
    Biomedicine & Pharmacotherapy.2025; 192: 118633.     CrossRef
  • Metabolic Dysfunction–Associated Steatotic Liver Disease in Pregnancy
    Hannah W. Han, Peter S. Marcus, Tse-Ling Fong
    Obstetrical & Gynecological Survey.2025; 80(10): 647.     CrossRef
  • Prevalence of Fibrosis and Applicability of Lab-Based Noninvasive Tests From Primary to Tertiary Care
    Georg Semmler, Paul Thöne, Jan Embacher, Philipp Hruska, Lucie Simonis, Katharina Stopfer, Laurenz Fritz, Fiona Köck, Lorenz Balcar, Benedikt S. Hofer, Bernhard Wernly, Sophie Gensluckner, Michael Strasser, Andreas Völkerer, Katrine Lindvig, Maja Thiele,
    Clinical Gastroenterology and Hepatology.2025;[Epub]     CrossRef
  • The emerging phenotype of nonalcoholic fatty liver disease in lean individuals: what’s different?
    Priyankar Dey
    Frontiers in Endocrinology.2025;[Epub]     CrossRef
  • Repurposing levothyroxine for managing metabolic dysfunction-associated steatotic liver disease
    Leonidas H. Duntas, Stergios A. Polyzos, Ulrike Gottwald-Hostalek, Bogumila Urgatz, Paul M. Yen
    Endocrine.2025; 90(3): 1043.     CrossRef
  • Triglyceride-cholesterol-body weight index associated with the risk of metabolic dysfunction-associated steatotic liver disease: a population-based cross-sectional study
    Li Fan, Yongkang Su, Yue Chen, Ling Xu, Hairong Huang, Chunsheng Lu, Jia Peng, Yingbin Sun, Min Jia
    Frontiers in Nutrition.2025;[Epub]     CrossRef
  • The Basics of Metabolic Dysfunction–Associated Steatotic Liver Disease for Cardiologists
    Muhammad Shahzeb Khan, Syed Sarmad Javaid, Amreen Dinani, Kara Wegermann, Ambarish Pandey, Ankeet S. Bhatt, Mark Muthiah, Harriette G.C. Van Spall, Faiez Zannad, Javed Butler, Michael L. Volk, Marat Fudim
    JACC.2025; 86(20): 1861.     CrossRef
  • Extracellular Matrix Microstructures Directly Regulate Glutathione Bioavailability in Human Hepatocytes
    John A. Terrell, Chengpeng Chen
    Biomacromolecules.2025; 26(12): 8475.     CrossRef
  • Analysis of Health-Related Quality of Life and Its Influencing Factors Among Patients with Non-Alcoholic Fatty Liver Disease in Hangzhou, China: A Cross-Sectional Study
    Han Fei, Kexin Lv, Jiayin Xu, Haojie Hao, Yidan Quan, Junping Shi, Wei Zhang
    Metabolic Syndrome and Related Disorders.2025; 23(7): 329.     CrossRef
  • CD209a regulates metabolic dysfunction-associated steatotic liver disease development through macrophage STAT3 signaling pathway
    Yishu Chen, Jiaming Zhou, Chenxi Tang, Pengwei Zhu, Zixin Xu, Xin Song, Jie Zhang, Li Cen, Hang Zeng, Yini Ke, Youming Li, Yi Chen, Jinghua Wang
    Cellular & Molecular Biology Letters.2025;[Epub]     CrossRef
  • MASLD: Lipotoxicity and Imaging Parallels from Liver Steatosis to Kidney Injury
    Sarmis Marian Săndulescu, Denisa Ștefania Ghiga, Diana Rodica Tudorașcu, Daniela Larisa Săndulescu, Adrian Mită, Marinela Cristiana Urhuț, Citto-Iulian Taisescu
    Life.2025; 15(12): 1805.     CrossRef
  • Metabolic dysfunction-associated steatotic liver disease in Egypt: Epidemiology, risk factors and management challenges
    Walaa Abdelhamed, Mona Amin, Imam Waked, Mohamed El-Kassas
    World Journal of Gastroenterology.2025;[Epub]     CrossRef
  • Folic Acid Combined with Melatonin Might Prevent Hepatic Steatosis by Alleviating Endoplasmic Reticulum Stress to Promote Lipid Droplet Lipolysis in High-Fat Diet-Fed Mice
    Dan Sun, Yanzhen Ma, Yixian Bai, Xue Bai, Weiheng Liu, Lin Du, Peng Wang, Xi Liang, Hui Liang, Huaqi Zhang
    Nutrients.2025; 17(23): 3641.     CrossRef
  • From liver to gut: the hidden gastrointestinal impact of pediatric metabolic dysfunction-associated steatotic liver disease
    Gianmario Forcina, Vittoria Frattolillo, Maria De Cesare, Assunta Floriano, Rosamaria Palma, Federica Casamassima, Mario Bartiromo, Pierluigi Marzuillo, Emanuele Miraglia del Giudice, Anna Di Sessa
    Expert Review of Gastroenterology & Hepatology.2025; 19(12): 1329.     CrossRef
  • Prevalence and severity of MASLD and fibrosis using transient elastography: A cross-sectional screening in Lower Mainland, British Columbia, Canada
    Kai Zhu, Harjot Bedi, Daljeet Chahal, Josh Kim, Eric M Yoshida, Peter Kwan
    Canadian Liver Journal.2025; 8(4): 580.     CrossRef
  • Transcriptomic Changes Underlying the Anti-Steatotic Effects of DHA Supplementation in Aged Obese Female Mice
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    International Journal of Molecular Sciences.2025; 26(23): 11689.     CrossRef
  • Antioxidant Capacity and Inhibition of Lipid Accumulation Effect of Baccharis articulata and Citrus sinensis Infusions
    Francisco Gualdieri, Gabriela Rocha, Ruben Iacono, Mauricio De Marzi, Liliana N. Guerra
    Plant Foods for Human Nutrition.2025;[Epub]     CrossRef
  • Hepatic steatosis in postmenopausal women is characterized by distinct serum extracellular vesicle proteomic signatures
    Patrick Pirrotte, Brooke Lovell, Siobán D. Harlow, Carrie A. Karvonen-Gutierrez, Michelle M. Hood, Ignazio S. Piras, Xiumei Wu, Melissa N. Martinez, Ritin Sharma, Krystine Garcia-Mansfield, Maya Willey, Johanna K. DiStefano
    BMC Medicine.2025;[Epub]     CrossRef
  • NEDD4L knockdown reduced lipid accumulation in non-alcoholic fatty liver disease by promoting the activity of PI3K/AKT signaling pathway
    Ju Zhou, Wu Li, Xiaowei Chi, Dingchun Li, Chunxia Yang, Zhiwen Duan
    European Journal of Medical Research.2025;[Epub]     CrossRef
  • The Prevalence of Fatty Liver Disease and Its Associated Factors Among Dayak Community in Kuching and Samarahan Division, Sarawak
    Azlan Arif Bolen, Jeffery Anak Stephen, Cheah Whye Lian, Koa Ai Jiun
    Malaysian Journal of Medicine and Health Sciences.2025; 21(2): 21.     CrossRef
  • The liver manifestation of metabolic syndrome is now called MASLD - an up-to-date view of the most common liver disease today
    Václav Šmíd, Karel Dvořák
    Vnitřní lékařství.2024; 70(1): E8.     CrossRef
  • Circulating fatty acids and risk of severe non-alcoholic fatty liver disease in the UK biobank: a prospective cohort of 116 223 individuals
    Pan Zhuang, Yang Ao, Xiaohui Liu, Hao Ye, Haoyu Li, Xuzhi Wan, Yu Zhang, Jingjing Jiao
    Food & Function.2024; 15(20): 10527.     CrossRef
  • The impact of gut microbiome-targeted therapy on liver enzymes in patients with nonalcoholic fatty liver disease: an umbrella meta-analysis
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    Nutrition Reviews.2024; 82(6): 815.     CrossRef
  • A global action agenda for turning the tide on fatty liver disease
    Jeffrey V. Lazarus, Henry E. Mark, Alina M. Allen, Juan Pablo Arab, Patrizia Carrieri, Mazen Noureddin, William Alazawi, Naim Alkhouri, Saleh A. Alqahtani, Quentin M. Anstee, Marco Arrese, Ramon Bataller, Thomas Berg, Paul N. Brennan, Patrizia Burra, Grac
    Hepatology.2024; 79(2): 502.     CrossRef
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    Caecilia HC Sukowati, Korri El-Khobar, Chyntia Olivia Maurine Jasirwan, Juferdy Kurniawan, Rino Alvani Gani
    Annals of Hepatology.2024; 29(1): 101153.     CrossRef
  • Can liquid biopsies for MASH help increase the penetration of metabolic surgery? A narrative review
    Lidia Castagneto-Gissey, Stefan R. Bornstein, Geltrude Mingrone
    Metabolism.2024; 151: 155721.     CrossRef
  • Reply
    Jong Woo Hahn, Soeun Kim, Dong Keon Yon
    Clinical Gastroenterology and Hepatology.2024; 22(4): 905.     CrossRef
  • Metabolic dysfunction associated steatotic liver disease: Current practice, screening guidelines and management in the primary care setting
    Udita Gupta, Thomas Ruli, Danyaal Buttar, Mohamed Shoreibah, Meagan Gray
    The American Journal of the Medical Sciences.2024; 367(2): 77.     CrossRef
  • Exclusive liquor and cocktail consumption is associated with at‐risk fibrosis among nonheavy alcohol users with metabolic dysfunction‐associated steatotic liver disease
    Peng‐sheng Ting, Wei‐Ting Lin, Chiung‐Kuei Huang, Hui‐Yi Lin, Tung‐Sung Tseng, Po‐Hung Chen
    Alcohol: Clinical and Experimental Research.2024; 48(1): 88.     CrossRef
  • Hepatocellular and extrahepatic cancer risk in people with non-alcoholic fatty liver disease
    James A Thomas, Bradley J Kendall, Hashem B El-Serag, Aaron P Thrift, Graeme A Macdonald
    The Lancet Gastroenterology & Hepatology.2024; 9(2): 159.     CrossRef
  • Compensated Advanced Chronic Liver Disease and Steatosis in Patients with Type 2 Diabetes as Assessed through Shear Wave Measurements and Attenuation Measurements
    Mislav Barisic-Jaman, Marko Milosevic, Viktoria Skurla, David Dohoczky, Josip Stojic, Petra Dinjar Kujundzic, Maja Cigrovski Berkovic, Ana Majic-Tengg, Ana Matijaca, Tomo Lucijanic, Mirjana Kardum-Pejic, Vlatka Pandzic Jaksic, Srecko Marusic, Ivica Grgure
    Biomedicines.2024; 12(2): 323.     CrossRef
  • Molecular Insights of Nonalcoholic Fatty Liver Disease Pathogenesis
    Reham Mohammed Dawood, Ghada Maher Salum, Mai Abd El-Meguid, Basma EL-sayed Fotouh
    Journal of Interferon & Cytokine Research.2024; 44(3): 111.     CrossRef
  • Prevalence, distribution, and hepatic fibrosis burden of the different subtypes of steatotic liver disease in primary care settings
    Chul-min Lee, Eileen L. Yoon, Mimi Kim, Bo-Kyeong Kang, Seon Cho, Eun-Hee Nah, Dae Won Jun
    Hepatology.2024; 79(6): 1393.     CrossRef
  • Proanthocyanidins-Based Synbiotics as a Novel Strategy for Nonalcoholic Fatty Liver Disease (NAFLD) Risk Reduction
    Wasitha P. D. W. Thilakarathna, H. P. Vasantha Rupasinghe
    Molecules.2024; 29(3): 709.     CrossRef
  • Suv39h1 contributes to activation of hepatic stellate cells in non-alcoholic fatty liver disease by enabling anaerobic glycolysis
    Xiaoyan Wu, Yuzhou Shen, Yufei Meng, Jinsi Chen, Yongchen Zhang, Sheng Zeng, Huihui Xu
    Life Sciences.2024; 341: 122498.     CrossRef
  • Self-management behaviours in adults with non-alcoholic fatty liver disease: a cross-sectional survey from China
    Run Zhou, Binbin Zhang, Wei Zhang, Tingting Kong, Jie Fu, Jie Li, Junping Shi
    BMJ Open.2024; 14(2): e078333.     CrossRef
  • Updated Insights into Probiotics and Hepatobiliary Diseases
    Xiaoyu Xu, Cheng Zhang, Guoyi Tang, Ning Wang, Yibin Feng
    Biomedicines.2024; 12(3): 515.     CrossRef
  • Disparities among ethnic groups in mortality and outcomes among adults with MASLD: A multicenter study
    Majd B. Aboona, Claire Faulkner, Pooja Rangan, Cheng Han Ng, Daniel Q. Huang, Mark Muthiah, Moises I. Nevah Rubin, Ma Ai Thanda Han, Michael B. Fallon, Donghee Kim, Vincent L. Chen, Karn Wijarnpreecha
    Liver International.2024; 44(6): 1316.     CrossRef
  • Optimizing surveillance of low-risk metabolic dysfunction associated steatotic liver disease using transient elastography
    Harish Gopalakrishna, Gayatri B. Nair, Roham Salman Roghani, Natarajan Ravendhran, Yaron Rotman
    European Journal of Gastroenterology & Hepatology.2024; 36(4): 476.     CrossRef
  • Implications of Protein and Sarcopenia in the Prognosis, Treatment, and Management of Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)
    Avneet Singh, Adam Buckholz, Sonal Kumar, Carolyn Newberry
    Nutrients.2024; 16(5): 658.     CrossRef
  • Proposal of a Novel Serological Algorithm Combining FIB-4 and Serum M2BPGi for Advanced Fibrosis in Nonalcoholic Fatty Liver Disease
    Sang Yi Moon, Yang Hyun Baek, Se Young Jang, Dae Won Jun, Ki Tae Yoon, Young Youn Cho, Hoon Gil Jo, Ae Jeong Jo
    Gut and Liver.2024; 18(2): 283.     CrossRef
  • Comprehensive meta-analysis reveals distinct gene expression signatures of MASLD progression
    Ignazio S Piras, Johanna K DiStefano
    Life Science Alliance.2024; 7(6): e202302517.     CrossRef
  • Global incidence of adverse clinical events in non-alcoholic fatty liver disease: A systematic review and meta-analysis
    Michael H. Le, David M. Le, Thomas C. Baez, Hansen Dang, Vy H. Nguyen, KeeSeok Lee, Christopher D. Stave, Takanori Ito, Yuankai Wu, Yee Hui Yeo, Fanpu Ji, Ramsey Cheung, Mindie H. Nguyen
    Clinical and Molecular Hepatology.2024; 30(2): 235.     CrossRef
  • In response to: Steatotic liver disease-know your enemies
    Michael H. Le, Linda Henry, Mindie H. Nguyen
    Clinical and Molecular Hepatology.2024; 30(2): 284.     CrossRef
  • Antiviral therapy response in patients with chronic hepatitis B and fatty liver: A systematic review and meta‐analysis
    Fajuan Rui, Elizabeth Garcia, Xinyu Hu, Wenjing Ni, Qi Xue, Yayun Xu, Xiaoming Xu, Junping Shi, Mindie H. Nguyen, Ramsey C. Cheung, Jie Li
    Journal of Viral Hepatitis.2024; 31(7): 372.     CrossRef
  • The impact of county-level food access on the mortality and post-transplant survival among patients with steatotic liver disease
    Yutaka Endo, Diamantis I. Tsilimigras, Mujtaba Khalil, Jason Yang, Selamawit Woldesenbet, Kazunari Sasaki, Ashley Limkemann, Austin Schenk, Timothy M. Pawlik
    Surgery.2024; 176(1): 196.     CrossRef
  • Omics-based biomarkers as useful tools in metabolic dysfunction-associated steatotic liver disease clinical practice: How far are we?
    Julieta Trinks, María F Mascardi, Adrián Gadano, Sebastián Marciano
    World Journal of Gastroenterology.2024; 30(14): 1982.     CrossRef
  • Burden of liver disease in Brazil, 1996–2022: a retrospective descriptive study of the epidemiology and impact on public healthcare
    João Sérgio Fonseca Guimarães, Jordana Almeida Mesquita, Thais Yuki Kimura, Ana Luíza Matos Oliveira, M. Fatima Leite, André Gustavo Oliveira
    The Lancet Regional Health - Americas.2024; 33: 100731.     CrossRef
  • The Global Epidemiology of Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis Among Patients With Type 2 Diabetes
    Zobair M. Younossi, Pegah Golabi, Jillian Kallman Price, Soroor Owrangi, Nagashree Gundu-Rao, Romona Satchi, James M. Paik
    Clinical Gastroenterology and Hepatology.2024; 22(10): 1999.     CrossRef
  • Molecular Genealogy of Metabolic-associated Hepatocellular Carcinoma
    Takahiro Kodama, Tetsuo Takehara
    Seminars in Liver Disease.2024; 44(02): 147.     CrossRef
  • Association between biological aging and the risk of mortality in individuals with non-alcoholic fatty liver disease: A prospective cohort study
    Haili Wang, Zhenqiu Liu, Hong Fan, Chengnan Guo, Xin Zhang, Yi Li, Xinyu Han, Tiejun Zhang
    Archives of Gerontology and Geriatrics.2024; 124: 105477.     CrossRef
  • An Electronic Health Record Model for Predicting Risk of Hepatic Fibrosis in Primary Care Patients
    Aaron P. Thrift, Theresa H. Nguyen Wenker, Kyler Godwin, Maya Balakrishnan, Hao T. Duong, Rohit Loomba, Fasiha Kanwal, Hashem B. El-Serag
    Digestive Diseases and Sciences.2024; 69(7): 2430.     CrossRef
  • Liver disease in patients with transfusion-dependent β-thalassemia: The emerging role of metabolism dysfunction-associated steatotic liver disease
    Nikolaos Fragkou, Efthimia Vlachaki, Ioannis Goulis, Emmanouil Sinakos
    World Journal of Hepatology.2024; 16(5): 671.     CrossRef
  • Single nucleotide polymorphisms in the cannabinoid CB2 receptor: Molecular pharmacology and disease associations
    Tahira Foyzun, Maddie Whiting, Kate K. Velasco, Jessie C. Jacobsen, Mark Connor, Natasha L. Grimsey
    British Journal of Pharmacology.2024; 181(15): 2391.     CrossRef
  • Diagnostic indicators and lifestyle interventions of metabolic-associated fatty liver disease
    Tianzhu Chen, Xiang Qin, Jianping Jiang, Beihui He
    Frontiers in Nutrition.2024;[Epub]     CrossRef
  • A global survey on the use of the international classification of diseases codes for metabolic dysfunction-associated fatty liver disease
    Huai Zhang, Giovanni Targher, Christopher D. Byrne, Seung Up Kim, Vincent Wai-Sun Wong, Luca Valenti, Myer Glickman, Jaime Ponce, Christos S. Mantzoros, Javier Crespo, Henning Gronbaek, Wah Yang, Mohammed Eslam, Robert J. Wong, Mariana Verdelho Machado, M
    Hepatology International.2024; 18(4): 1178.     CrossRef
  • Association between hemoglobin and non-alcoholic fatty liver disease (NAFLD) in United States adults: Results from NHANES 2017–2020
    Kang Yao, Zheng Chen, Wei Zhou, Zhihua Liu, Wei Cui
    Preventive Medicine Reports.2024; 44: 102798.     CrossRef
  • Mapping the global research landscape on nonalcoholic fatty liver disease and insulin resistance: A visualization and bibliometric study
    Sa'ed H Zyoud, Omar E Hegazi, Samer O Alalalmeh, Muna Shakhshir, Faris Abushamma, Shadi Khilfeh, Samah W Al-Jabi
    World Journal of Hepatology.2024; 16(6): 951.     CrossRef
  • Diagnostic performance of CT/MRI LI-RADS v2018 in non-cirrhotic steatotic liver disease
    Jennie Cao, Andy Shon, Luke Yoon, Aya Kamaya, Justin R. Tse
    European Radiology.2024; 34(12): 7622.     CrossRef
  • Persons with metabolic dysfunction‐associated steatotic liver disease are at increased risk of severe depression
    Hanne Åström, Ying Shang, Hannes Hagström, Axel Wester
    Liver International.2024; 44(10): 2551.     CrossRef
  • An examination of global research trends for exploring the associations between the gut microbiota and nonalcoholic fatty liver disease through bibliometric and visualization analysis
    Sa’ed H. Zyoud, Samer O. Alalalmeh, Omar E. Hegazi, Muna Shakhshir, Faris Abushamma, Samah W. Al-Jabi
    Gut Pathogens.2024;[Epub]     CrossRef
  • Mechanism of epigallocatechin gallate in treating non-alcoholic fatty liver disease: Insights from network pharmacology and experimental validation
    Danting Mao, Jianwei Guo, Kunli Yang, Fan Yang, Jiaojiao Peng, Xu Jia, Ziren Luo, Lu Liu, Enjie Yang, Rui Tang, Haitao Lan, Qian Zheng
    Biochemical and Biophysical Research Communications.2024; 734: 150424.     CrossRef
  • Dysfunctional VLDL metabolism in MASLD
    Urko M. Marigorta, Oscar Millet, Shelly C. Lu, José M. Mato
    npj Metabolic Health and Disease.2024;[Epub]     CrossRef
  • A systematic review and meta-analysis of randomized controlled trials: effects of mediterranean diet and low-fat diet on liver enzymes and liver fat content of NAFLD
    Yalan Xiong, Xinyu Shi, Xinying Xiong, Shenyu Li, Hanhua Zhao, Hualing Song, Jianying Wang, Lei Zhang, Shengfu You, Guang Ji, Baocheng Liu, Na Wu
    Food & Function.2024; 15(16): 8248.     CrossRef
  • Food inequity and insecurity and MASLD: burden, challenges, and interventions
    Shira Zelber-Sagi, Patrizia Carrieri, Juan M. Pericàs, Dana Ivancovsky-Wajcman, Zobair M. Younossi, Jeffrey V. Lazarus
    Nature Reviews Gastroenterology & Hepatology.2024; 21(10): 668.     CrossRef
  • A Precision Medicine Guided Approach to the Utilization of Biomarkers in MASLD
    Nimish Thakral, Hailemichael Desalegn, Luis Antonio Diaz, Daniel Cabrera, Rohit Loomba, Marco Arrese, Juan Pablo Arab
    Seminars in Liver Disease.2024; 44(03): 273.     CrossRef
  • Resmetirom and Metabolic Dysfunction-Associated Steatohepatitis: Perspectives on Multidisciplinary Management from Global Healthcare Professionals
    Kahei Au, Ming-Hua Zheng, Wei-Jei Lee, Omar M. Ghanem, Kamal Mahawar, Asim Shabbir, Carel W. le Roux, Giovanni Targher, Christopher D. Byrne, Yusuf Yilmaz, Luca Valenti, Giada Sebastiani, Sombat Treeprasertsuk, Hannah Xiaoyan Hui, Nasser Sakran, Manoel Ga
    Current Obesity Reports.2024; 13(4): 818.     CrossRef
  • Immune system dysregulation in the pathogenesis of non-alcoholic steatohepatitis: unveiling the critical role of T and B lymphocytes
    Merve Cebi, Yusuf Yilmaz
    Frontiers in Immunology.2024;[Epub]     CrossRef
  • Synergistic association of sodium-glucose cotransporter-2 inhibitor and metformin on liver and non-liver complications in patients with type 2 diabetes mellitus and metabolic dysfunction-associated steatotic liver disease
    Xianhua Mao, Xinrong Zhang, Leslie Kam, Nicholas Chien, Rongtao Lai, Ka-Shing Cheung, Man-Fung Yuen, Ramsey Cheung, Wai-Kay Seto, Mindie H Nguyen
    Gut.2024; 73(12): 2054.     CrossRef
  • Pathophysiological Relationship between Type 2 Diabetes Mellitus and Metabolic Dysfunction-Associated Steatotic Liver Disease: Novel Therapeutic Approaches
    Shifat-E Ferdous, Jessica M. Ferrell
    International Journal of Molecular Sciences.2024; 25(16): 8731.     CrossRef
  • Novel insights into causal effects of maternal nonalcoholic fatty liver disease on adverse pregnancy outcomes: evidence from Human Genetics and Mendelian Randomization Study
    Qiuyan Luo, Guoting Liu, Qiulan Li, Jinghong Lu, Wenjing Zheng, Yukui Huang, Cun Li
    European Journal of Clinical Nutrition.2024; 78(12): 1041.     CrossRef
  • Role of Growth Hormone Therapy in Metabolic-Dysfunction-Associated Steatotic Liver Disease: A Systematic Review and Meta-Analysis
    Deep Dutta, Lakshmi Nagendra, Ritin Mohindra, Saptarshi Bhattacharya, Ameya Joshi, ABM Kamrul-Hasan
    Indian Journal of Endocrinology and Metabolism.2024; 28(4): 336.     CrossRef
  • Meta-analysis of randomized controlled trials of the effects of synbiotics, probiotics, or prebiotics in controlling glucose homeostasis in non-alcoholic fatty liver disease patients
    Siqi Ding, Qing Hong, Yuanyue Yao, Minwen Gu, Jie Cui, Wenhui Li, Jian Zhang, Chengcheng Zhang, Jinchi Jiang, Yonghong Hu
    Food & Function.2024; 15(19): 9954.     CrossRef
  • The Clínica Universidad de Navarra-Body Adiposity Estimator index is a reliable tool for screening metabolic dysfunction-associated steatotic liver disease: an analysis from a gender perspective
    Chao Wang, Xin Huang, Shiming He, Maobin Kuang, Guobo Xie, Guotai Sheng, Yang Zou
    Lipids in Health and Disease.2024;[Epub]     CrossRef
  • Systemic treatment of hepatocellular carcinoma secondary to non-alcoholic fatty liver disease
    Karolina Rzeniewicz, Rohini Sharma
    World Journal of Clinical Oncology.2024; 15(11): 1394.     CrossRef
  • Invited Commentary: Radiology at the Forefront in the Fight against Metabolic Dysfunction–associated Steatotic Liver Disease
    Sudhakar K. Venkatesh
    RadioGraphics.2024;[Epub]     CrossRef
  • Visceral Obesity and Its Association with Severe Coronary Artery Calcification in Patients with Metabolic Dysfunction-Associated Steatotic Liver Disease
    Min Kyu Kang, Jeung Eun Song, Young Oh Kweon, Won Young Tak, Soo Young Park, Yu Rim Lee, Jung Gil Park
    Diagnostics.2024; 14(20): 2305.     CrossRef
  • Metabolic-associated fatty liver disease is less effective in predicting mortality than non-alcoholic fatty liver disease and metabolic dysfunction-associated steatotic liver disease: Letter to the editor on “Prognosis of biopsy-confirmed metabolic dysfun
    Yixuan Zhu, Xiaoyan Ma, Wenjing Ni, Yee Hui Yeo, Junping Shi, Jie Li
    Clinical and Molecular Hepatology.2024; 30(4): 974.     CrossRef
  • Incidence rates of hepatocellular carcinoma based on risk stratification in steatotic liver disease for precision medicine: A real-world longitudinal nationwide study
    Rongtao Lai, Scott Barnett, Xinrong Zhang, Leslie Yeeman Kam, Ramsey Cheung, Qing Xie, Mindie H. Nguyen, Gilaad G. Kaplan
    PLOS Medicine.2024; 21(10): e1004479.     CrossRef
  • DNA methylome analysis reveals epigenetic alteration of complement genes in advanced metabolic dysfunction-associated steatotic liver disease
    Amal Magdy, Hee-Jin Kim, Hanyong Go, Jun Min Lee, Hyun Ahm Sohn, Keeok Haam, Hyo-Jung Jung, Jong-Lyul Park, Taekyeong Yoo, Eun-Soo Kwon, Dong Hyeon Lee, Murim Choi, Keon Wook Kang, Won Kim, Mirang Kim
    Clinical and Molecular Hepatology.2024; 30(4): 824.     CrossRef
  • Modelo Wistar de doença hepática gordurosa não alcoólica: indução por fonte natural de colesterol
    Maysa Ortolani Matera, Gabriel dos Santos, Maíza Pelissari Migliorini, Karyn Maria Wenglarek, Thais de Lima da Silva, Flávia Cristina Colmenero, Isabela Hess Justus, Bruna Karas, Marcelo de Oliveira Dreweck, Sérgio Ossamu Ioshii, Mario Claudio Soares Stur
    Cuadernos de Educación y Desarrollo.2024; 16(11): e6263.     CrossRef
  • Machine-Learning Application for Predicting Metabolic Dysfunction-Associated Steatotic Liver Disease Using Laboratory and Body Composition Indicators
    Fatemeh Masaebi, Mehdi Azizmohammad Looha, Morteza Mohammadzadeh, Vida Pahlevani, Mojtaba Farjam, Farid Zayeri, Reza Homayounfar
    Archives of Iranian Medicine.2024; 27(10): 551.     CrossRef
  • Coexisting metabolic dysfunction-associated steatotic liver disease exacerbates in-hospital outcomes in patients with heat stroke
    Ping Zhang, Guo Tang, Hongguang Gao, Tianshan Zhang, Sha Yang, Tao Cheng, Rong Yao
    Frontiers in Medicine.2024;[Epub]     CrossRef
  • Trends in Hepatocellular Carcinoma Mortality Rates in the US and Projections Through 2040
    Sikai Qiu, Jiangying Cai, Zhanpeng Yang, Xinyuan He, Zixuan Xing, Jian Zu, Enrui Xie, Linda Henry, Custis R. Chong, Esther M. John, Ramsey Cheung, Fanpu Ji, Mindie H. Nguyen
    JAMA Network Open.2024; 7(11): e2445525.     CrossRef
  • Doença hepática gordurosa não alcoólica experimental induzida por dieta rica em colesterol
    Maíza Pellissari Migliorini, Gabriel dos Santos, Maysa Ortolani Matera, Karyn Maria Wenglarek, Thais de Lima da Silva, Jaqueline Meert Parlow, Isabela Hess Justus, Flávia Cristina Colmenero, Marcelo de Oliveira Dreweck, Sérgio Ossamu Ioshii, Mário Cláudio
    Cuadernos de Educación y Desarrollo.2024; 16(11): e6598.     CrossRef
  • Comparative analysis of NAFLD-related health videos on TikTok: a cross-language study in the USA and China
    Hongyu Wu, Jialun Peng, Shengwei Li, Xiong Ding, Tao Zhong, Qilong Zhai, Changjie Du, Jiajun Yuan, Can Cai, Jinzheng Li
    BMC Public Health.2024;[Epub]     CrossRef
  • Contribution of Sex Differences to Development of Cardiovascular Disease in Metabolic-Associated Steatotic Liver Disease (MASLD)
    Lucy C. Taylor, Gertrude Arthur, Marcella de Carvalho Cruz, David E. Stec, Olufunto O. Badmus
    International Journal of Translational Medicine.2024; 4(4): 782.     CrossRef
  • Metabolic dysfunction associated fatty liver disease identifies subjects with cardiovascular risk better than non‐alcoholic fatty liver disease
    Ho Soo Chun, Minjong Lee, Jae Seung Lee, Hye Won Lee, Beom Kyung Kim, Jun Yong Park, Do Young Kim, Sang Hoon Ahn, Yong‐Ho Lee, Ji‐Hye Kim, Seung Up Kim
    Liver International.2023; 43(3): 608.     CrossRef
  • Correspondence on Editorial regarding “Screening and prediction of nonalcoholic fatty liver disease using a peripheral insulin resistance index: Potential benefits and limitations”
    Jun-Hyuk Lee, Kyongmin Park, Hye Sun Lee, Hoon-Ki Park, Jee Hye Han, Sang Bong Ahn
    Clinical and Molecular Hepatology.2023; 29(1): 185.     CrossRef
  • Clinical Implications of Cardiac Symptoms and Electrocardiographic Abnormalities for Advanced Liver Fibrosis in Patients with Nonalcoholic Fatty Liver Disease
    Min-Kyu Kang, Min-Cheol Kim
    Medicina.2023; 59(2): 375.     CrossRef
  • The independent effect of exercise on biopsy-proven non-alcoholic fatty liver disease: A systematic review
    George Chen, Bubu Banini, Albert Do, Joseph K. Lim
    Clinical and Molecular Hepatology.2023; 29(Suppl): S319.     CrossRef
  • Global incidence and prevalence of nonalcoholic fatty liver disease
    Margaret LP Teng, Cheng Han Ng, Daniel Q. Huang, Kai En Chan, Darren JH Tan, Wen Hui Lim, Ju Dong Yang, Eunice Tan, Mark D. Muthiah
    Clinical and Molecular Hepatology.2023; 29(Suppl): S32.     CrossRef
  • Noninvasive serum biomarkers for liver steatosis in nonalcoholic fatty liver disease: Current and future developments
    Sang Bong Ahn
    Clinical and Molecular Hepatology.2023; 29(Suppl): S150.     CrossRef
  • The effects of moderate alcohol consumption on non-alcoholic fatty liver disease
    Hyunwoo Oh, Won Sohn, Yong Kyun Cho
    Clinical and Molecular Hepatology.2023; 29(Suppl): S261.     CrossRef
  • Surveillance of the progression and assessment of treatment endpoints for nonalcoholic steatohepatitis
    Yi-wen Shi, Jian-Gao Fan
    Clinical and Molecular Hepatology.2023; 29(Suppl): S228.     CrossRef
  • Risk Stratification for Sarcopenic Obesity in Nonalcoholic Fatty Liver Disease
    Rongtao Lai, Mindie H. Nguyen
    Clinical Gastroenterology and Hepatology.2023; 21(11): 2984.     CrossRef
  • The independent effect of exercise on biopsy proven non-alcoholic fatty liver disease: A systematic review
    Young-Joo Jin
    Clinical and Molecular Hepatology.2023; 29(2): 414.     CrossRef
  • The growing burden of non-alcoholic fatty liver disease on mortality
    Ju-Yeon Cho, Won Sohn
    Clinical and Molecular Hepatology.2023; 29(2): 374.     CrossRef
  • Glucagon-like Peptide-1 Receptor Agonists in Patients with Type 2 Diabetes Mellitus and Nonalcoholic Fatty Liver Disease—Current Background, Hopes, and Perspectives
    Georgiana-Diana Cazac, Cristina-Mihaela Lăcătușu, Gabriela Ștefănescu, Cătălina Mihai, Elena-Daniela Grigorescu, Alina Onofriescu, Bogdan-Mircea Mihai
    Metabolites.2023; 13(5): 581.     CrossRef
  • The Role of Choline, Soy Isoflavones, and Probiotics as Adjuvant Treatments in the Prevention and Management of NAFLD in Postmenopausal Women
    Johanna K. DiStefano
    Nutrients.2023; 15(12): 2670.     CrossRef
  • Mechanisms Linking Metabolic-Associated Fatty Liver Disease (MAFLD) to Cardiovascular Disease
    Olufunto O. Badmus, Terry D. Hinds, David E. Stec
    Current Hypertension Reports.2023; 25(8): 151.     CrossRef
  • Cardiovascular outcomes among persons with HIV and nonalcoholic fatty liver disease
    Sepiso K. Masenga, Lweendo Muchaili, Benson M. Hamooya
    AIDS.2023; 37(8): 1329.     CrossRef
  • Efficacy and safety of tirzepatide for treatment of overweight or obesity. A systematic review and meta-analysis
    Bryan Tan, Xin-Hui Pan, Han Shi Jocelyn Chew, Rachel Sze Jen Goh, Chaoxing Lin, Vickram Vijay Anand, Ethan Cheng Zhe Lee, Kai En Chan, Gwyneth Kong, Christen En Ya Ong, Hui Charlotte Chung, Dan Yock Young, Mark Y. Chan, Chin Meng Khoo, Anurag Mehta, Mark
    International Journal of Obesity.2023; 47(8): 677.     CrossRef
  • Non-Alcoholic Fatty Liver Disease: Translating Disease Mechanisms into Therapeutics Using Animal Models
    Amina Basha, Sarah C. May, Ryan M. Anderson, Niharika Samala, Raghavendra G. Mirmira
    International Journal of Molecular Sciences.2023; 24(12): 9996.     CrossRef
  • Transient elastography with controlled attenuation parameter versus two-dimensional shear wave elastography with attenuation imaging for the evaluation of hepatic steatosis and fibrosis in NAFLD
    Jung Wook Seo, Youe Ree Kim, Jong Keon Jang, So Yeon Kim, Young Youn Cho, Eun Sun Lee, Dong Ho Lee
    Ultrasonography.2023; 42(3): 421.     CrossRef
  • The impact of concomitant metabolic dysfunction-associated fatty liver disease on adverse outcomes in patients with hepatitis B cirrhosis: a propensity score matching study
    Xinyu Wang, Shuhang Wei, Yingnan Wei, Xueqi Wang, Feng Xiao, Yuemin Feng, Qiang Zhu
    European Journal of Gastroenterology & Hepatology.2023; 35(8): 889.     CrossRef
  • Lifestyle interventions in nonalcoholic fatty liver disease
    Zobair M. Younossi, Shira Zelber-Sagi, Linda Henry, Lynn H. Gerber
    Nature Reviews Gastroenterology & Hepatology.2023; 20(11): 708.     CrossRef
  • The latest evidence on the impact of fatty liver on liver-related outcomes and mortality in chronic hepatitis B
    Xianhua Mao, Lung Yi Mak, Wai-Kay Seto
    Clinical and Molecular Hepatology.2023; 29(3): 690.     CrossRef
  • Liver biopsy-based validation, confirmation and comparison of the diagnostic performance of established and novel non-invasive steatotic liver disease indexes: Results from a large multi-center study
    Matina Kouvari, Laura Valenzuela-Vallejo, Valentina Guatibonza-Garcia, Stergios A. Polyzos, Yixiang Deng, Michail Kokkorakis, Melih Agraz, Sophia C. Mylonakis, Angeliki Katsarou, Ornella Verrastro, Georgios Markakis, Mohammed Eslam, Georgios Papatheodorid
    Metabolism.2023; 147: 155666.     CrossRef
  • Ca2+ signaling and the Hippo pathway: Intersections in cellular regulation
    Samar Sayedyahossein, Louise Thines, David B. Sacks
    Cellular Signalling.2023; 110: 110846.     CrossRef
  • The first external validation of the Dallas steatosis index in biopsy-proven Non-alcoholic fatty liver Disease: A multicenter study
    Matina Kouvari, Sophia C. Mylonakis, Angeliki Katsarou, Laura Valenzuela-Vallejo, Valentina Guatibonza-Garcia, Michail Kokkorakis, Ornella Verrastro, Giulia Angelini, Georgios Markakis, Mohammed Eslam, Jacob George, Georgios Papatheodoridis, Geltrude Ming
    Diabetes Research and Clinical Practice.2023; 203: 110870.     CrossRef
  • Uniting to defeat steatotic liver disease: A global mission to promote healthy livers and healthy lives
    Aleksander Krag, Maria Buti, Jeffrey V. Lazarus, Alina M. Allen, Jacqueline Bowman, Patrizia Burra, Giacomo Donnini, Ajay Duseja, Manal H. El-Sayed, Amalia Gastaldelli, Ben Hainsworth, Tom H. Karlsen, Michael Kessler, Marko Korenjak, Henry E. Mark, Jake P
    Journal of Hepatology.2023; 79(5): 1076.     CrossRef
  • Unraveling the link between insulin resistance and Non-alcoholic fatty liver disease (or metabolic dysfunction-associated steatotic liver disease): A Narrative Review
    Fateme Ziamanesh, Mehdi Mohammadi, Sholeh Ebrahimpour, Ozra Tabatabaei-Malazy, Asieh Mosallanejad, Bagher Larijani
    Journal of Diabetes & Metabolic Disorders.2023; 22(2): 1083.     CrossRef
  • Global health burden of cirrhosis and other chronic liver diseases (CLDs) due to non-alcoholic fatty liver disease (NAFLD): A systematic analysis for the global burden of disease study 2019
    Jie Li, Qingzhi Wang, Wenjing Ni, Chuan Liu, Zhihui Li, Xiaolong Qi
    Global Transitions.2023; 5: 160.     CrossRef
  • The Impact of Intermittent Fasting on Non-Alcoholic Fatty Liver Disease in Older Adults: A Review of Clinicaltrials.gov Registry
    Nasser Alorfi, Ahmed Ashour
    Diabetes, Metabolic Syndrome and Obesity.2023; Volume 16: 3115.     CrossRef
  • Update on the Obesity Epidemic: After the Sudden Rise, Is the Upward Trajectory Beginning to Flatten?
    Chrysi Koliaki, Maria Dalamaga, Stavros Liatis
    Current Obesity Reports.2023; 12(4): 514.     CrossRef
  • Metabolic-Dysfunction-Associated Steatotic Liver Disease—Its Pathophysiology, Association with Atherosclerosis and Cardiovascular Disease, and Treatments
    Hidekatsu Yanai, Hiroki Adachi, Mariko Hakoshima, Sakura Iida, Hisayuki Katsuyama
    International Journal of Molecular Sciences.2023; 24(20): 15473.     CrossRef
  • An integrated gene-to-outcome multimodal database for metabolic dysfunction-associated steatotic liver disease
    Timothy J. Kendall, Maria Jimenez-Ramos, Frances Turner, Prakash Ramachandran, Jessica Minnier, Michael D. McColgan, Masood Alam, Harriet Ellis, Donald R. Dunbar, Gabriele Kohnen, Prakash Konanahalli, Karin A. Oien, Lucia Bandiera, Filippo Menolascina, An
    Nature Medicine.2023; 29(11): 2939.     CrossRef
  • Association of nonalcoholic fatty liver disease and growth hormone deficiency: a systematic review and meta-analysis
    Tingting Kong, Yunpeng Gu, Lei Sun, Run Zhou, Jie Li, Junping Shi
    Endocrine Journal.2023; 70(10): 959.     CrossRef
  • Magnetic resonance elastography-based prediction model for hepatic decompensation in NAFLD: A multicenter cohort study
    Beom Kyung Kim, Jaclyn Bergstrom, Rohan Loomba, Nobuharu Tamaki, Namiki Izumi, Atsushi Nakajima, Ramazan Idilman, Mesut Gumussoy, Digdem K. Oz, Ayse Erden, Emily Truong, Ju Dong Yang, Mazen Noureddin, Alina M. Allen, Rohit Loomba, Veeral Ajmera
    Hepatology.2023; 78(6): 1858.     CrossRef
  • The Impact and Burden of Dietary Sugars on the Liver
    Helaina E. Huneault, Ana Ramirez Tovar, Cristian Sanchez-Torres, Jean A. Welsh, Miriam B. Vos
    Hepatology Communications.2023;[Epub]     CrossRef
  • Transcriptomics of MASLD Pathobiology in African American Patients in the Washington DC Area †
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    International Journal of Molecular Sciences.2023; 24(23): 16654.     CrossRef
  • Racial and ethnic differences and the role of unfavorable social determinants of health across steatotic liver disease subtypes in the United States
    Pedro Ochoa-Allemant, Jorge A. Marrero, Marina Serper
    Hepatology Communications.2023;[Epub]     CrossRef
  • The Influence of Coffee on Reducing Metabolic Dysfunction-Associated Steatotic Liver Disease in Patients With Type 2 Diabetes: A Review
    Manpreet Kaur, Shanmathi Murugesan, Sachpreet Singh, Katherine N Uy, Jasjeet Kaur, Navina Mann, Rajneet K Sekhon
    Cureus.2023;[Epub]     CrossRef
  • International diet quality index and revised diet quality index relationship with non-alcoholic fatty liver disease: a case-control study
    Narjes Najibi, Mitra Kazemi Jahromi, Farshad Teymoori, Hossein Farhadnejad, Ammar Salehi-Sahlabadi, Parvin Mirmiran
    BMC Gastroenterology.2023;[Epub]     CrossRef
  • Developmental Programming: Impact of Prenatal Exposure to Bisphenol A on Senescence and Circadian Mediators in the Liver of Sheep
    Giuliana Motta, Soundara Viveka Thangaraj, Vasantha Padmanabhan
    Toxics.2023; 12(1): 15.     CrossRef
  • Nonalcoholic fatty liver disease: a review of physiology, treatments, and market outlook
    Pammar Aryan
    Advances in Tissue Engineering & Regenerative Medicine: Open Access.2023; 9(1): 42.     CrossRef
  • Non-Alcoholic Fatty Liver Disease, Atherosclerosis, and Cardiovascular Disease in Asia
    Yohwan Lim, Seogsong Jeong, Myunghee Hong, Hyun Wook Han
    Reviews in Cardiovascular Medicine.2023;[Epub]     CrossRef
  • 21,920 View
  • 469 Download
  • 274 Web of Science
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Editorials

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  • Association of four insulin resistance indices with liver‐related adverse outcomes: A prospective cohort study
    Xiao‐Meng Wang, Hao Yan, Wen‐Fang Zhong, Jia‐Hao Xie, Huan Chen, Jun‐Jie Wang, Wei‐Qi Song, Dong Shen, Pei‐Dong Zhang, Xi‐Ru Zhang, Jiao‐Jiao Ren, Dan Liu, Zhi‐Hao Li, Chen Mao
    Diabetes, Obesity and Metabolism.2026; 28(5): 3598.     CrossRef
  • Non-linear association of the metabolic score for insulin resistance with obstructive sleep apnea: a cross-sectional study from NHANES 2015–2018
    Zhimao Cai, Jiachen Li, Hui Peng, Ye Ye, Sixia Chen, Lingli Zeng, Jiashuang Lin, Weifeng Chen
    Frontiers in Nutrition.2025;[Epub]     CrossRef
  • Metabolic syndrome, social isolation, and sarcopenia in mild cognitive impairment: A multifaceted analysis of risk factors and mediating pathways
    Shuang Deng, Zhongqiang Guo, Min Liu, Marwan Salih Al-Nimer
    PLOS One.2025; 20(10): e0333266.     CrossRef
  • Association between METS-IR and heart failure: a cross-sectional study
    Xiaozhou Su, Chunli Zhao, Xianwei Zhang
    Frontiers in Endocrinology.2024;[Epub]     CrossRef
  • Understanding Insulin Resistance in NAFLD: A Systematic Review and Meta-Analysis Focused on HOMA-IR in South Asians
    Margeyi Mehta, Jigish Shah, Urvish Joshi
    Cureus.2024;[Epub]     CrossRef
  • Correspondence on Editorial regarding “Screening and prediction of nonalcoholic fatty liver disease using a peripheral insulin resistance index: Potential benefits and limitations”
    Jun-Hyuk Lee, Kyongmin Park, Hye Sun Lee, Hoon-Ki Park, Jee Hye Han, Sang Bong Ahn
    Clinical and Molecular Hepatology.2023; 29(1): 185.     CrossRef
  • Letter regarding “The usefulness of metabolic score for insulin resistance for the prediction of incident non-alcoholic fatty liver disease in Korean adults”
    Hye Won Lee
    Clinical and Molecular Hepatology.2023; 29(1): 169.     CrossRef
  • 7,696 View
  • 97 Download
  • 6 Web of Science
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  • MASLD in the oldest-old: lack of association with cognition or functional autonomy and poor predictive utility of the hepatic steatosis index
    Maximilian Joseph Brol, Martin Groth, Frank Erhard Uschner, Juliana Stadtmann, Tina Schomacher, Jonel Trebicka, Michael Praktiknjo, Elena Vorona
    GeroScience.2025;[Epub]     CrossRef
  • Correspondence on Letter regarding “Non-alcoholic fatty liver disease: Definition and subtypes”
    Seul Ki Han, Soon Koo Baik, Moon Young Kim
    Clinical and Molecular Hepatology.2023; 29(3): 817.     CrossRef
  • Risk of dementia in the elderly with non-alcoholic fatty liver disease: A nested case-control study in the Republic of Korea
    Sung Hwan Yoo, Ju-Young Park, Hye Sun Lee, Hyun Woong Lee, Jung Il Lee
    Annals of the Academy of Medicine, Singapore.2023; 52(11): 570.     CrossRef
  • 6,483 View
  • 93 Download
  • 2 Web of Science
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Original Article

Steatotic liver disease

Prevalence trends of non-alcoholic fatty liver disease among young men in Korea: A Korean military population-based cross-sectional study
Jaejun Lee, Taeyun Kim, Hyun Yang, Si Hyun Bae
Clin Mol Hepatol 2022;28(2):196-206.
Published online January 13, 2022
DOI: https://doi.org/10.3350/cmh.2021.0371
Background/Aims
Non-alcoholic fatty liver disease (NAFLD) has become a major concern in Korea since its emergence as a dominant cause of chronic liver disease. However, no study has explored its prevalence in adults under 30 years of age. Therefore, we performed a cross-sectional study to investigate the prevalence of NAFLD in Korean men in their early 20s.
Methods
We collected data of 596,359 Korean soldiers who participated in a health examination between January 2015 and July 2021. A total of 571,872 individuals were analyzed after excluding those with missing data and hepatitis B antigen positivity. Hepatic steatosis was determined using the hepatic steatosis index (HSI). Participants with HSI >36 were considered to have NAFLD.
Results
All participants were men, and the mean age was 20.9±1.3 years. Of the 571,872 participants screened, 77,020 (13.47%) were classified as having NAFLD. The prevalence of NAFLD consistently increased from 2015 to 2021 (10.66% vs. 16.44%, P<0.001). Increases from 2015 to 2021 were also noted in the prevalence of hypercholesterolemia, hyperglycemia, and hypertension (P<0.001 for all). The mean body mass index also increased from 23.3±3.0 kg/m2 to 23.9±3.1 kg/m2 between 2015 and 2021 (P<0.001).
Conclusions
The prevalence of NAFLD and of other metabolic dysfunctions in Korean men in their early 20s increased from 2015 to 2021.

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Citations to this article as recorded by  Crossref logo
  • PNPLA3 I148M is unrelated to HCC occurrence but associates with poorer tumor differentiation in Korean MASLD: a prospective cohort of 562 patients
    Jaejun Lee, Dong Yeop Lee, Jung Hoon Cha, Hee Sun Cho, Keungmo Yang, Hyun Yang, Mi Young Byun, Seok Keun Cho, Seong Wook Yang, Si Hyun Bae, Pil Soo Sung
    Journal of Liver Cancer.2026; 26(1): 147.     CrossRef
  • Predictive factors of MASLD in young adults: A systematic review and narrative synthesis
    Moirangthem Jeena Devi, Anita Malhotra, Piyush Ranjan, Manisha Sabharwal, Aditi Verma, Nikita Madan, Archana Kumari, Maroof A. Khan, Upendra Baitha, Bindu Prakash
    Diabetes & Metabolic Syndrome: Clinical Research & Reviews.2026; 20(5): 103435.     CrossRef
  • Surgically confirmed severe endometriosis is associated with lower risk of steatotic liver disease: Evidence of estrogen‐linked hepatic–reproductive crosstalk
    Jung Hyun Park, Keungmo Yang, Hyun Yang, Si Hyun Bae, Mee‐Ran Kim, Jaejun Lee
    International Journal of Gynecology & Obstetrics.2026;[Epub]     CrossRef
  • Association Between Thyroid Function Indicators and Metabolic‐Associated Fatty Liver Disease: Effect Modification by Iodine Nutritional Status
    Wei Huang, Jiang Yao, Yunzhen Shi, Heyong Huang, Suraiya Saleem
    International Journal of Endocrinology.2026;[Epub]     CrossRef
  • Appendicular skeletal muscle mass is associated with metabolic dysfunction-associated steatotic liver disease severity in young men: a cross-sectional and longitudinal study
    Jaejun Lee, Jinson So, Chang In Han, Hyun Yang, Pil Soo Sung, Si Hyun Bae, Do Seon Song
    Hepatology International.2025; 19(1): 181.     CrossRef
  • Differential Exercise Requirements for Nonalcoholic Fatty Liver Disease Resolution Across Age Groups: A Longitudinal Study of Korean Military Officers
    Jaejun Lee, Dong Yeup Lee, Jae Hyeop Jung, Eunkyoung Bae, Jeong A. Yu, Hyun Yang
    Journal of Physical Activity and Health.2025; 22(3): 323.     CrossRef
  • Performance of Noninvasive Indices for Discrimination of Metabolic Dysfunction-Associated Steatotic Liver Disease in Young Adults
    Jaejun Lee, Chang In Han, Dong Yeup Lee, Pil Soo Sung, Si Hyun Bae, Hyun Yang
    Gut and Liver.2025; 19(1): 116.     CrossRef
  • A Literature Review of Glutathione Therapy in Ameliorating Hepatic Dysfunction in Non-Alcoholic Fatty Liver Disease
    Michelle Thuy Nguyen, Andrew Lian, Frederick Timothy Guilford, Vishwanath Venketaraman
    Biomedicines.2025; 13(3): 644.     CrossRef
  • Effect of treadmill walking on cardiometabolic risk factors and liver function markers in older adults with MASLD: a randomized controlled trial
    Jiyoun Kim, Sungju Lee, Yong-Seok Jee
    BMC Sports Science, Medicine and Rehabilitation.2025;[Epub]     CrossRef
  • Association Between Nonalcoholic Fatty Liver Disease and Risk of Early-onset Colorectal Cancer
    Seulji Kim, Jin-Hyung Jung, Kyungdo Han, Seong-Joon Koh, Jong Pil Im, Byeong Gwan Kim, Joo Sung Kim, Hyun Jung Lee
    Clinical Gastroenterology and Hepatology.2025; 23(13): 2550.     CrossRef
  • Prevalence of Non-alcoholic Fatty Liver Disease in Iran: A Systematic Review and Meta-analysis
    Seidamir P. Tabaeian, Aziz Rezapour, Samad Azari, Mariano Martini, Maryam Saran, Meysam Behzadifar, Saeed Shahabi, Abdollah Sayyad, Ali Tahernejad, N.L. Bragazzi, S.J. Ehsanzadeh, Masoud Behzadifar
    Journal of Clinical and Experimental Hepatology.2024; 14(1): 101209.     CrossRef
  • Impact of Overseas Deployment on Fatty Liver and Metabolic Diseases Among Korean Soldiers
    Chang In Han, Jaejun Lee
    Military Medicine.2024; 189(7-8): e1621.     CrossRef
  • Impact of Korean Military Service on the Prevalence of Steatotic Liver Disease: A Longitudinal Study of Pre-enlistment and In-Service Health Check-Ups
    Jaejun Lee, Jae Hyeop Jung, Sung Jun Choi, Beomman Ha, Hyun Yang, Pil Soo Sung, Si Hyun Bae, Jeong-A Yu
    Gut and Liver.2024; 18(5): 888.     CrossRef
  • Serum uric acid and nonalcoholic fatty liver disease
    Jia Fan, Dongxu Wang
    Frontiers in Endocrinology.2024;[Epub]     CrossRef
  • Metabolic dysfunction associated fatty liver disease identifies subjects with cardiovascular risk better than non‐alcoholic fatty liver disease
    Ho Soo Chun, Minjong Lee, Jae Seung Lee, Hye Won Lee, Beom Kyung Kim, Jun Yong Park, Do Young Kim, Sang Hoon Ahn, Yong‐Ho Lee, Ji‐Hye Kim, Seung Up Kim
    Liver International.2023; 43(3): 608.     CrossRef
  • Global incidence and prevalence of nonalcoholic fatty liver disease
    Margaret LP Teng, Cheng Han Ng, Daniel Q. Huang, Kai En Chan, Darren JH Tan, Wen Hui Lim, Ju Dong Yang, Eunice Tan, Mark D. Muthiah
    Clinical and Molecular Hepatology.2023; 29(Suppl): S32.     CrossRef
  • Preventive effect of empagliflozin and ezetimibe on hepatic steatosis in adults and murine models
    Dong Yun Kim, Kyu Sik Chung, Jun Yong Park, Heon Yung Gee
    Biomedicine & Pharmacotherapy.2023; 161: 114445.     CrossRef
  • Liver transplantation for non-alcoholic fatty liver disease: indications and post-transplant management
    Sara Battistella, Francesca D’Arcangelo, Marco Grasso, Alberto Zanetto, Martina Gambato, Giacomo Germani, Marco Senzolo, Francesco Paolo Russo, Patrizia Burra
    Clinical and Molecular Hepatology.2023; 29(Suppl): S286.     CrossRef
  • Surveillance of the progression and assessment of treatment endpoints for nonalcoholic steatohepatitis
    Yi-wen Shi, Jian-Gao Fan
    Clinical and Molecular Hepatology.2023; 29(Suppl): S228.     CrossRef
  • Bariatric surgery for non-alcoholic fatty liver disease: Indications and post-operative management
    Anja Geerts, Sander Lefere
    Clinical and Molecular Hepatology.2023; 29(Suppl): S276.     CrossRef
  • The effects of moderate alcohol consumption on non-alcoholic fatty liver disease
    Hyunwoo Oh, Won Sohn, Yong Kyun Cho
    Clinical and Molecular Hepatology.2023; 29(Suppl): S261.     CrossRef
  • Fatty Liver & Diabetes Statistics in Korea: Nationwide Data 2009 to 2017
    Eugene Han, Kyung-Do Han, Yong-ho Lee, Kyung-Soo Kim, Sangmo Hong, Jung Hwan Park, Cheol-Young Park
    Diabetes & Metabolism Journal.2023; 47(3): 347.     CrossRef
  • Low‐quality muscle mass rather than normal‐quality muscle mass determines fibrosis progression in biopsy‐proven NAFLD
    Yun Kyu Lee, Bo Kyung Koo, Sae Kyung Joo, Dong Hyeon Lee, Heejoon Jang, Jee Won Chai, Myoung Seok Lee, Si Won Jang, Young Ho So, Jeong Hwan Park, Mee Soo Chang, Won Kim
    Alimentary Pharmacology & Therapeutics.2023; 58(3): 322.     CrossRef
  • Analysis of risk factors related to nonalcoholic fatty liver disease: a retrospective study based on 31,718 adult Chinese individuals
    Ganggang Wang, Xiaowei Shen, Yicun Wang, Huanhua Lu, Hua He, Xiaoliang Wang
    Frontiers in Medicine.2023;[Epub]     CrossRef
  • A survey on the awareness, current management, and barriers for non-alcoholic fatty liver disease among the general Korean population
    Jun-Hyuk Lee, Jang Han Jung, Huiyul Park, Joo Hyun Oh, Sang Bong Ahn, Eileen Laurel Yoon, Dae Won Jun
    Scientific Reports.2023;[Epub]     CrossRef
  • Muscle Mass Adjusted for Body Weight Is Associated with Significant Liver Fibrosis in Young Adults with Nonalcoholic Fatty Liver Disease: A Cross-Sectional Study from a Korean Military Hospital
    Jaejun Lee, Seongjoo Na, Taeyun Kim, Seong-Woo Lee, Myoung Jung Kim, Chang In Han, Si Hyun Bae
    Journal of Obesity & Metabolic Syndrome.2023; 32(3): 279.     CrossRef
  • Screening and prediction of nonalcoholic fatty liver disease using a peripheral insulin resistance index: Potential benefits and limitations
    Soon Sun Kim, Jae Youn Cheong
    Clinical and Molecular Hepatology.2022; 28(4): 802.     CrossRef
  • 11,681 View
  • 236 Download
  • 27 Web of Science
  • Crossref

Review

Steatotic liver disease

From nonalcoholic fatty liver disease to metabolic-associated fatty liver disease: Big wave or ripple?
Seong Hee Kang, Yuri Cho, Soung Won Jeong, Seung Up Kim, Jin-Woo Lee, On behalf of Korean NAFLD Study Group
Clin Mol Hepatol 2021;27(2):257-269.
Published online March 22, 2021
DOI: https://doi.org/10.3350/cmh.2021.0067
There is some dissatisfaction with the term “nonalcoholic fatty liver disease (NAFLD),” which overemphasizes alcohol and underemphasizes the importance of metabolic risk factors in this disease. Recently, a consensus recommended “metabolic (dysfunction)-associated fatty liver disease (MAFLD)” as a more appropriate term to describe fatty liver diseases (FLD) associated with metabolic dysfunction. During the definition change from NAFLD to MAFLD, subjects with FLD and metabolic abnormalities, together with other etiologies of liver diseases such as alcohol, virus, or medication who have been excluded from the NAFLD criteria, were added to the MAFLD criteria, while subjects with FLD but without metabolic abnormality, who have been included in the NAFLD criteria, were excluded from the MAFLD criteria. This means that there is an emphasis on the metabolic dysfunction in MAFLD which may underestimate the prognostic value of hepatic steatosis itself, whereas the MAFLD criteria might better identify subjects who are at a higher risk of hepatic or cardiovascular outcomes. However, non-metabolic risk NAFLD subjects who are excluded from the MAFLD criteria are missed from the diagnosis, and their potential risk can be the cause of future diseases. Although huge controversies remain, this review focused on summarizing recent studies that compared the clinical and prognostic characteristics between subjects with NAFLD and MAFLD.

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    Gut and Liver.2026; 20(1): 125.     CrossRef
  • Integrating body composition analysis and machine learning for non-invasive identification of metabolic dysfunction-associated fatty liver disease: a large-scale health examination-based study
    Yaxuan He, Yu Cao, Zekai Chen, Rong Xiang, Fang Wang
    Scientific Reports.2026;[Epub]     CrossRef
  • Association between the Zhejiang University index and metabolic dysfunction-associated fatty liver disease as analyzed in National Health and Nutrition Examination Survey: A retrospective observational study
    Wei Fu, Xiaoyue Wu, Guobin Cheng, Linya Lyu, Hulin Wang
    Journal of International Medical Research.2026;[Epub]     CrossRef
  • Association Between Dietary Patterns and Sarcopenia in Patients With Liver Cirrhosis: A Cross‐Sectional Study
    Elham Sobhrakhshankhah, Parvin Hassanzadeh, Soghra Karimi, Mohsen Reza Mansoorian, Naemeh Kolahdoozan, Azam Doustmohammadian
    Health Science Reports.2026;[Epub]     CrossRef
  • Research Progress of the Relationship between Metabolic-Associated Fatty Liver Disease and Colorectal Neoplasia
    杨 包
    Advances in Clinical Medicine.2025; 15(02): 1996.     CrossRef
  • Liver-Kidney Crosstalk in Major Pediatric Diseases: Unraveling the Complexities and Clinical Challenges
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    Journal of Clinical Medicine.2025; 14(11): 3911.     CrossRef
  • The utility of an artificial intelligence model based on decision tree and evolution algorithm to evaluate steatotic liver disease in a primary care setting
    A.C. Goulart, A.P. Alencar, G. Tunes, L.L.T. Bianchi, M.H. Miname, C.M. Padilha, J.M.S. Pescuma, A.L.C.C. Rodrigues, B.B. Henares, M.S. de Almeida, T.A.O. Machado, D.H. Syllos, Y.P. Wang, M. Rienzo
    Brazilian Journal of Medical and Biological Research.2025;[Epub]     CrossRef
  • Prevalence and risk factors of metabolic associated fatty liver disease in lean patients with bipolar disorder: a retrospective cross-sectional study
    Weihong Lei, Jiahuan Li, Yiyi Liu, Ying Wang, Qing Wu
    Frontiers in Endocrinology.2025;[Epub]     CrossRef
  • Tracking Mutual Interactions of Mitochondria/Lysosomes/Lipid Droplets in DILI and NAFLD with a Viscosity and Peroxynitrite-Sensitive Single Fluorescent Probe
    Chunhua Fan, Xionghao Xu, Bo Zhao, Tao Jiang, Tianxin Liu, Chaewoon Cho, Juyoung Yoon, Zhengliang Lu
    Analytical Chemistry.2025; 97(40): 21935.     CrossRef
  • Redefining fatty liver as metabolic dysfunction-associated steatotic liver disease: Implications of nomenclature changes for patients with diabetes
    Tulio L Correa, Nikki Duong
    World Journal of Hepatology.2025;[Epub]     CrossRef
  • Metabolic Dysfunction-Associated Fatty Liver Disease and Chronic Viral Hepatitis: The Interlink
    Cornelius J. Fernandez, Mohammed Alkhalifah, Hafsa Afsar, Joseph M. Pappachan
    Pathogens.2024; 13(1): 68.     CrossRef
  • High prevalence of fatty liver and its association with metabolic syndrome among rural adults with chronic hepatitis C: Implications for primary healthcare
    Ta-Jen Wang, Mei-Yen Chen, Yu-Chih Lin, Wen-Nan Chiu, Tung-Jung Huang, Hsu-Huei Weng
    BMC Public Health.2024;[Epub]     CrossRef
  • Genome-wide association study of metabolic dysfunction-associated fatty liver disease in a Korean population
    Young Lee, Eun Ju Cho, Eun Kyung Choe, Min-Sun Kwak, Jong In Yang, Seung-Won Oh, Jeong Yoon Yim, Goh Eun Chung
    Scientific Reports.2024;[Epub]     CrossRef
  • Prevalence of NAFLD, MAFLD, and MASLD: NHANES 1999-2018
    Jie Pan, Feilong Wu, Mingtao Chen, Jinsen He, Yingying Gu, Lei Pei, Xuye Lai, Zhenfeng Zhang, Lili Yang
    Diabetes & Metabolism.2024; 50(6): 101562.     CrossRef
  • Comparative associations of MASLD and MAFLD with the presence and severity of coronary artery calcification
    Min Kyu Kang, Jeong Eun Song, Rohit Loomba, Soo Young Park, Won Young Tak, Young Oh Kweon, Yu Rim Lee, Jung Gil Park
    Scientific Reports.2024;[Epub]     CrossRef
  • Visceral Obesity and Its Association with Severe Coronary Artery Calcification in Patients with Metabolic Dysfunction-Associated Steatotic Liver Disease
    Min Kyu Kang, Jeung Eun Song, Young Oh Kweon, Won Young Tak, Soo Young Park, Yu Rim Lee, Jung Gil Park
    Diagnostics.2024; 14(20): 2305.     CrossRef
  • Metabolic dysfunction-associated fatty liver disease: bridging cardiology and hepatology
    Xiao-Dong Zhou, Giovanni Targher, Christopher D. Byrne, Michael D. Shapiro, Li-Li Chen, Ming-Hua Zheng
    Cardiology Plus.2024; 9(4): 275.     CrossRef
  • Does metabolic dysfunction-associated fatty liver disease increase the risk of chronic kidney disease? A meta-analysis of cohort studies
    Wanghao Liu, Xiaoying Sun
    BMC Nephrology.2024;[Epub]     CrossRef
  • Leukocyte telomere length decreased the risk of mortality in patients with alcohol-associated liver disease
    Jiahong Yi, Hui Guo, Chang Jiang, Junyi Duan, Ju Xue, Yue Zhao, Wenzhuo He, Liangping Xia
    Frontiers in Endocrinology.2024;[Epub]     CrossRef
  • Nonalcoholic Fatty Liver Disease Without Metabolic-associated Fatty Liver Disease and the Risk of Metabolic Syndrome
    Dong Hyun Sinn, Danbee Kang, Sung Chul Choi, Yun Soo Hong, Di Zhao, Eliseo Guallar, Yewan Park, Juhee Cho, Geum-Youn Gwak
    Clinical Gastroenterology and Hepatology.2023; 21(7): 1873.     CrossRef
  • Non-alcoholic fatty liver disease establishment and progression: genetics and epigenetics as relevant modulators of the pathology
    Camila Cristiane Pansa, Letícia Ramos Molica, Karen C. M. Moraes
    Scandinavian Journal of Gastroenterology.2023; 58(5): 521.     CrossRef
  • Comparable Mortality Between Asian Patients with Chronic Hepatitis B Under Long-Term Antiviral Therapy vs Matched Control: A Population-Based Study
    Byungyoon Yun, Juyeon Oh, Sang Hoon Ahn, Jin-Ha Yoon, Beom Kyung Kim
    American Journal of Gastroenterology.2023; 118(6): 1001.     CrossRef
  • Statin use is associated with better post‐operative prognosis among patients with hepatitis B virus‐related hepatocellular carcinoma
    Byungyoon Yun, Sang Hoon Ahn, Juyeon Oh, Jin‐Ha Yoon, Beom Kyung Kim
    European Journal of Clinical Investigation.2023;[Epub]     CrossRef
  • Lean or diabetic subtypes predict increased all-cause and disease-specific mortality in metabolic-associated fatty liver disease
    Goh Eun Chung, Su Jong Yu, Jeong-Ju Yoo, Yuri Cho, Kyu-na Lee, Dong Wook Shin, Donghee Kim, Yoon Jun Kim, Jung-Hwan Yoon, Kyungdo Han, Eun Ju Cho
    BMC Medicine.2023;[Epub]     CrossRef
  • Metabolic dysfunction associated fatty liver disease identifies subjects with cardiovascular risk better than non‐alcoholic fatty liver disease
    Ho Soo Chun, Minjong Lee, Jae Seung Lee, Hye Won Lee, Beom Kyung Kim, Jun Yong Park, Do Young Kim, Sang Hoon Ahn, Yong‐Ho Lee, Ji‐Hye Kim, Seung Up Kim
    Liver International.2023; 43(3): 608.     CrossRef
  • The independent effect of exercise on biopsy-proven non-alcoholic fatty liver disease: A systematic review
    George Chen, Bubu Banini, Albert Do, Joseph K. Lim
    Clinical and Molecular Hepatology.2023; 29(Suppl): S319.     CrossRef
  • Preventive strategy for nonalcoholic fatty liver disease-related hepatocellular carcinoma
    Yuri Cho, Bo Hyun Kim, Joong-Won Park
    Clinical and Molecular Hepatology.2023; 29(Suppl): S220.     CrossRef
  • Associations between Adipokines and Metabolic Dysfunction-Associated Fatty Liver Disease Using Three Different Diagnostic Criteria
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    Journal of Clinical Medicine.2023; 12(6): 2126.     CrossRef
  • Chinese Visceral Adipose Index Shows Superior Diagnostic Performance in Predicting the Risk of Metabolic Dysfunction Associated Fatty Liver Disease in Early Postmenopausal Chinese Women
    Yayun Lu, Lingxia Ge, Hao Yang, Yufeng He, Yujun Wang
    Diabetes, Metabolic Syndrome and Obesity.2023; Volume 16: 607.     CrossRef
  • Non-invasive imaging biomarkers for liver steatosis in non-alcoholic fatty liver disease: present and future
    Asako Nogami, Masato Yoneda, Michihiro Iwaki, Takashi Kobayashi, Yasushi Honda, Yuji Ogawa, Kento Imajo, Satoru Saito, Atsushi Nakajima
    Clinical and Molecular Hepatology.2023; 29(Suppl): S123.     CrossRef
  • Non-alcoholic fatty liver disease: Definition and subtypes
    Seul Ki Han, Soon Koo Baik, Moon Young Kim
    Clinical and Molecular Hepatology.2023; 29(Suppl): S5.     CrossRef
  • MAFLD: How is it different from NAFLD?
    Cameron Gofton, Yadhavan Upendran, Ming-Hua Zheng, Jacob George
    Clinical and Molecular Hepatology.2023; 29(Suppl): S17.     CrossRef
  • Clinical and histologic factors associated with discordance between steatosis grade derived from histology vs. MRI‐PDFF in NAFLD
    Beom K. Kim, Nicole Bernstein, Daniel Q. Huang, Nobuharu Tamaki, Kento Imajo, Masato Yoneda, Nancy Sutter, Jinho Jung, Khang Nguyen, Leyna Nguyen, Tracy Le, Egbert Madamba, Lisa Richards, Mark A. Valasek, Cynthia Behling, Claude B. Sirlin, Atsushi Nakajim
    Alimentary Pharmacology & Therapeutics.2023; 58(2): 229.     CrossRef
  • Chronic hepatitis B with concurrent metabolic dysfunction-associated fatty liver disease: Challenges and perspectives
    Shang-Chin Huang, Chun-Jen Liu
    Clinical and Molecular Hepatology.2023; 29(2): 320.     CrossRef
  • Impact of metabolic factors on risk of cardiovascular disease in nondiabetic metabolic dysfunction-associated fatty liver disease
    Min Kyu Kang, Yu Rim Lee, Se Young Jang, Won Young Tak, Young Oh Kweon, Jeong Eun Song, Rohit Loomba, Soo Young Park, Jung Gil Park
    Hepatology International.2023; 17(3): 626.     CrossRef
  • Efficacy and safety of tirzepatide for treatment of overweight or obesity. A systematic review and meta-analysis
    Bryan Tan, Xin-Hui Pan, Han Shi Jocelyn Chew, Rachel Sze Jen Goh, Chaoxing Lin, Vickram Vijay Anand, Ethan Cheng Zhe Lee, Kai En Chan, Gwyneth Kong, Christen En Ya Ong, Hui Charlotte Chung, Dan Yock Young, Mark Y. Chan, Chin Meng Khoo, Anurag Mehta, Mark
    International Journal of Obesity.2023; 47(8): 677.     CrossRef
  • Differential risk of 23 site‐specific incident cancers and cancer‐related mortality among patients with metabolic dysfunction‐associated fatty liver disease: a population‐based cohort study with 9.7 million Korean subjects
    Goh Eun Chung, Su Jong Yu, Jeong‐Ju Yoo, Yuri Cho, Kyu‐na Lee, Dong Wook Shin, Yoon Jun Kim, Jung‐Hwan Yoon, Kyungdo Han, Eun Ju Cho
    Cancer Communications.2023; 43(8): 863.     CrossRef
  • MAFLD might be better in identifying subjects with sarcopenia or cardiovascular risk than NAFLD: A nationwide study
    Eugene Han, Ho Soo Chun, Yong‐ho Lee, Jae Seung Lee, Hye Won Lee, Beom Kyung Kim, Jun Yong Park, Do Young Kim, Byung‐Wan Lee, Eun Seok Kang, Bong‐Soo Cha, Sang Hoon Ahn, Seung Up Kim
    Journal of Gastroenterology and Hepatology.2023; 38(9): 1598.     CrossRef
  • Metabolic dysfunction-associated fatty liver disease and the risk of hepatocellular carcinoma
    Byeong Geun Song, Sung Chul Choi, Myung Ji Goh, Wonseok Kang, Dong Hyun Sinn, Geum-Youn Gwak, Yong-Han Paik, Moon Seok Choi, Joon Hyeok Lee, Seung Woon Paik
    JHEP Reports.2023; 5(9): 100810.     CrossRef
  • Nonalcoholic fatty liver disease without overlapping metabolic‐associated fatty liver disease and the risk of incident type 2 diabetes
    Yoosun Cho, Yoosoo Chang, Seungho Ryu, Sarah H. Wild, Christopher D. Byrne
    Liver International.2023; 43(11): 2445.     CrossRef
  • The impact of concomitant metabolic dysfunction-associated fatty liver disease on adverse outcomes in patients with hepatitis B cirrhosis: a propensity score matching study
    Xinyu Wang, Shuhang Wei, Yingnan Wei, Xueqi Wang, Feng Xiao, Yuemin Feng, Qiang Zhu
    European Journal of Gastroenterology & Hepatology.2023; 35(8): 889.     CrossRef
  • Metabolic dysfunction: The silenced connection with fatty liver disease
    Mariana M. Ramírez-Mejía, Xingshun Qi, Ludovico Abenavoli, Manuel Romero-Gómez, Mohammed Eslam, Nahum Méndez-Sánchez
    Annals of Hepatology.2023; 28(6): 101138.     CrossRef
  • Fibrotic Burden in the Liver Differs Across Metabolic Dysfunction-Associated Fatty Liver Disease Subtypes
    Tae Seop Lim, Ho Soo Chun, Soon Sun Kim, Ja Kyung Kim, Minjong Lee, Hyo Jung Cho, Seung Up Kim, Jae Youn Cheong
    Gut and Liver.2023; 17(4): 610.     CrossRef
  • Diabetic MAFLD is associated with increased risk of hepatocellular carcinoma and mortality in chronic viral hepatitis patients
    Mi Na Kim, Kyungdo Han, Juhwan Yoo, Seong Gyu Hwang, Xuehong Zhang, Sang Hoon Ahn
    International Journal of Cancer.2023; 153(8): 1448.     CrossRef
  • Coagulation Dysfunctions in Non-Alcoholic Fatty Liver Disease—Oxidative Stress and Inflammation Relevance
    Madalina Andreea Robea, Ioana-Miruna Balmus, Irina Girleanu, Laura Huiban, Cristina Muzica, Alin Ciobica, Carol Stanciu, Carmen Diana Cimpoesu, Anca Trifan
    Medicina.2023; 59(9): 1614.     CrossRef
  • From Nonalcoholic Steatohepatits to Steatotic Liver Disease: A Long Way
    Helma Cotrim
    Diagnostics.2023; 13(19): 3104.     CrossRef
  • Impact of Porphyromonas gingivalis -odontogenic infection on the pathogenesis of non-alcoholic fatty liver disease
    Linbo Liu, Yan Geng, Chaoliang Xiong
    Annals of Medicine.2023;[Epub]     CrossRef
  • Critical appraisal of metabolic dysfunction-associated steatotic liver disease: Implication of Janus-faced modernity
    Gi-Ae Kim, Joon Ho Moon, Won Kim
    Clinical and Molecular Hepatology.2023; 29(4): 831.     CrossRef
  • Correlation between serum uric acid and body fat distribution in patients with MAFLD
    Min Tao, Jing Liu, Xingyu Chen, Qing Wang, Miao He, Wenwen Chen, Cong Wang, Lili Zhang
    BMC Endocrine Disorders.2023;[Epub]     CrossRef
  • Increased detection rates of advanced colorectal adenoma in women with metabolic dysfunction-associated fatty liver disease
    Yan Gong, Juan Kang, Xinyan Wang, Yansong Zheng, Ying Sui, Wenping Lu
    Heliyon.2023; 9(11): e22391.     CrossRef
  • Inhibition of Dickkopf-1 enhances the anti-tumor efficacy of sorafenib via inhibition of the PI3K/Akt and Wnt/β-catenin pathways in hepatocellular carcinoma
    Sang Hyun Seo, Kyung Joo Cho, Hye Jung Park, Hye Won Lee, Beom Kyung Kim, Jun Yong Park, Do Young Kim, Sang Hoon Ahn, Jae Hee Cheon, Jong In Yook, Man-Deuk Kim, Dong Jin Joo, Seung Up Kim
    Cell Communication and Signaling.2023;[Epub]     CrossRef
  • The relationship between skeletal muscle mass to visceral fat area ratio and metabolic dysfunction-associated fatty liver disease subtypes in middle-aged and elderly population: a single-center retrospective study
    Mengchen Xing, Yanlan Ni, Ye Zhang, Xiaoqian Zhao, Xin Yu
    Frontiers in Nutrition.2023;[Epub]     CrossRef
  • The Transition of Cardiovascular Disease Risks from NAFLD to MAFLD
    Zifeng Yang, Juan Yang, Jingjing Cai, Xiao-Jing Zhang, Peng Zhang, Zhi-Gang She, Hongliang Li
    Reviews in Cardiovascular Medicine.2023;[Epub]     CrossRef
  • Non-Alcoholic Fatty Liver Disease, Atherosclerosis, and Cardiovascular Disease in Asia
    Yohwan Lim, Seogsong Jeong, Myunghee Hong, Hyun Wook Han
    Reviews in Cardiovascular Medicine.2023;[Epub]     CrossRef
  • Prognostic Impact of MAFLD Following Surgical Resection of Hepatitis B Virus-Related Hepatocellular Carcinoma: A Nationwide Cohort Study
    Byungyoon Yun, Sang Hoon Ahn, Juyeon Oh, Jin-Ha Yoon, Beom Kyung Kim
    Cancers.2022; 14(20): 5002.     CrossRef
  • Nonalcoholic Fatty Liver Disease Is a Precursor of New-Onset Metabolic Syndrome in Metabolically Healthy Young Adults
    Jeong-Ju Yoo, Eun Ju Cho, Goh Eun Chung, Young Chang, Yuri Cho, Sang-Hyun Park, Su-Min Jeong, Bo-Yeon Kim, Dong Wook Shin, Yun Joon Kim, Jung-Hwan Yoon, Kyungdo Han, Su Jong Yu
    Journal of Clinical Medicine.2022; 11(4): 935.     CrossRef
  • Non-alcoholic/Metabolic-Associated Fatty Liver Disease and Helicobacter pylori Additively Increase the Risk of Arterial Stiffness
    Ji Min Choi, Hyo Eun Park, Yoo Min Han, Jooyoung Lee, Heesun Lee, Su Jin Chung, Seon Hee Lim, Jeong Yoon Yim, Goh Eun Chung
    Frontiers in Medicine.2022;[Epub]     CrossRef
  • Metabolic dysfunction-associated fatty liver disease and risk of incident chronic kidney disease: A nationwide cohort study
    Chan-Young Jung, Hee Byung Koh, Keun Hyung Park, Young Su Joo, Hyung Woo Kim, Sang Hoon Ahn, Jung Tak Park, Seung Up Kim
    Diabetes & Metabolism.2022; 48(4): 101344.     CrossRef
  • Empirically-Derived Dietary Patterns in Relation to Non-Alcoholic Fatty Liver Diseases Among Adult Participants in Amol, Northern Iran: A Structural Equation Modeling Approach
    Azam Doustmohammadian, Elham Pishgar, Cain C. T. Clark, Elham Sobhrakhshankhah, Mehdi Nikkhah, Amir Hossein Faraji, Nima Motamed, Mohsen Reza Mansourian, Bahareh Amirkalali, Mansooreh Maadi, Maryam Sadat Kasaii, Hamidreza Ebrahimi, Farhad Zamani
    Frontiers in Nutrition.2022;[Epub]     CrossRef
  • MAFLD enhances clinical practice for liver disease in the Asia-Pacific region
    Takumi Kawaguchi, Tsubasa Tsutsumi, Dan Nakano, Mohammed Eslam, Jacob George, Takuji Torimura
    Clinical and Molecular Hepatology.2022; 28(2): 150.     CrossRef
  • The Importance of Metabolic Syndrome Status for the Risk of Non-Viral Hepatocellular Carcinoma: A Nationwide Population-Based Study
    Yuri Cho, Eun Ju Cho, Jeong-Ju Yoo, Young Chang, Goh Eun Chung, In Young Choi, Sang-Hyun Park, Kyungdo Han, Yoon Jun Kim, Jung-Hwan Yoon, Dong Wook Shin, Su Jong Yu
    Frontiers in Oncology.2022;[Epub]     CrossRef
  • Advances in pediatric non-alcoholic fatty liver disease: From genetics to lipidomics
    Simona Riccio, Rosa Melone, Caterina Vitulano, Pierfrancesco Guida, Ivan Maddaluno, Stefano Guarino, Pierluigi Marzuillo, Emanuele Miraglia del Giudice, Anna Di Sessa
    World Journal of Clinical Pediatrics.2022; 11(3): 221.     CrossRef
  • MAFLD Predicts the Risk of Cardiovascular Disease Better than NAFLD in Asymptomatic Subjects with Health Check-Ups
    Hyoeun Kim, Chan Joo Lee, Sang Hoon Ahn, Kwan Sik Lee, Byoung Kwon Lee, Su Jung Baik, Seung Up Kim, Jung Il Lee
    Digestive Diseases and Sciences.2022; 67(10): 4919.     CrossRef
  • From NAFLD to MAFLD: Not just a change in the name
    Jing Zeng, Jian-Gao Fan
    Hepatobiliary & Pancreatic Diseases International.2022; 21(6): 511.     CrossRef
  • I148M variant of PNPLA3-gene is not associated with metabolic syndrome in patients with NAFLD in the Indian ethnicity
    Govardhan Bale, Sasikala Mitnala, Nagaraja Rao Padaki, Mithun Sharma, Anand V. Kulkarni, Smita C. Pawar, Nageshwar Reddy D, Ravikanth Vishnubhotla
    Human Gene.2022; 33: 201073.     CrossRef
  • Metabolic-associated fatty liver disease from childhood to adulthood: State of art and future directions
    Francesca Lanzaro, Stefano Guarino, Elisabetta D'Addio, Alessandra Salvatori, Josè Alberto D'Anna, Pierluigi Marzuillo, Emanuele Miraglia del Giudice, Anna Di Sessa
    World Journal of Hepatology.2022; 14(6): 1087.     CrossRef
  • Metabolic Dysfunction-Associated Fatty Liver Disease Better Predicts Incident Cardiovascular Disease
    Seogsong Jeong, Yun Hwan Oh, Seulggie Choi, Jooyoung Chang, Sung Min Kim, Joung Sik Son, Gyeongsil Lee, Won Kim, Sang Min Park
    Gut and Liver.2022; 16(4): 589.     CrossRef
  • New Insights into Non-Alcoholic Fatty Liver Disease and Coronary Artery Disease: The Liver-Heart Axis
    Georgiana-Diana Cazac, Cristina-Mihaela Lăcătușu, Cătălina Mihai, Elena-Daniela Grigorescu, Alina Onofriescu, Bogdan-Mircea Mihai
    Life.2022; 12(8): 1189.     CrossRef
  • Effect of metabolic dysfunction‐associated fatty liver disease on liver cancer risk in a population with chronic hepatitis B virus infection: A nationwide study
    Byungyoon Yun, Sang Hoon Ahn, Juyeon Oh, Jin‐Ha Yoon, Beom Kyung Kim
    Hepatology Research.2022; 52(12): 975.     CrossRef
  • Ultrasound-Based Hepatic Elastography in Non-Alcoholic Fatty Liver Disease: Focus on Patients with Type 2 Diabetes
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    Biomedicines.2022; 10(10): 2375.     CrossRef
  • Non-alcoholic fatty liver disease: a global concern
    Gerri Mortimore
    Practice Nursing.2022; 33(9): 358.     CrossRef
  • Prevalence and clinical characteristics of patients with metabolic dysfunction‐associated fatty liver disease with hepatitis C virus infection—a population‐based study
    Dina Attia, Shereen Abdel Alem, Wafaa El‐Akel, Wael Abdel‐Razek, Mohamed Eslam, Yasser Fouad, Imam Waked
    Alimentary Pharmacology & Therapeutics.2022; 56(11-12): 1581.     CrossRef
  • Comparison of non-invasive imaging methods and laboratory findings on non-alcoholic fatty liver disease (NAFLD) in childhood
    Caner DOĞAN, Meryem KEÇELİ BAŞARAN, Okan GÜRKAN, Seda GÜLEÇ GEYLANİ
    Journal of Health Sciences and Medicine.2022; 5(6): 1541.     CrossRef
  • Impact of MAFLD on HBV-Related Stage 0/A Hepatocellular Carcinoma after Curative Resection
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    Journal of Personalized Medicine.2021; 11(8): 684.     CrossRef
  • Metabolic Fatty Liver Disease in Children: A Growing Public Health Problem
    Sébastien Le Garf, Véronique Nègre, Rodolphe Anty, Philippe Gual
    Biomedicines.2021; 9(12): 1915.     CrossRef
  • The Risk of Colorectal Adenoma in Nonalcoholic or Metabolic-Associated Fatty Liver Disease
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    Biomedicines.2021; 9(10): 1401.     CrossRef
  • Association between telomere length and hepatic fibrosis in non-alcoholic fatty liver disease
    Hee Kyung Shin, Jeong Hwan Park, Jung Hwan Yu, Young-Joo Jin, Young Ju Suh, Jin-Woo Lee, Won Kim
    Scientific Reports.2021;[Epub]     CrossRef
  • Risk stratification using sarcopenia status among subjects with metabolic dysfunction‐associated fatty liver disease
    Ho Soo Chun, Mi Na Kim, Jae Seung Lee, Hye Won Lee, Beom Kyung Kim, Jun Yong Park, Do Young Kim, Sang Hoon Ahn, Seung Up Kim
    Journal of Cachexia, Sarcopenia and Muscle.2021; 12(5): 1168.     CrossRef
  • Diabetes and metabolic dysfunction-associated fatty liver disease
    Timothy M.E. Davis
    Metabolism.2021; 123: 154868.     CrossRef
  • Functions of two distinct Kupffer cells in the liver
    Chunye Zhang, Shuai Liu, Ming Yang
    Exploration of Medicine.2021; : 511.     CrossRef
  • The Change in Metabolic Syndrome Status and the Risk of Nonviral Liver Cirrhosis
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    Biomedicines.2021; 9(12): 1948.     CrossRef
  • 15,187 View
  • 463 Download
  • 79 Web of Science
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Original Article

Artificial intelligence, epidemiology, methodology, or others

Serum milk fat globule-EGF factor 8 protein as a potential biomarker for metabolic syndrome
Han Ah Lee, Jihwan Lim, Hyung Joon Joo, Young-Sun Lee, Young Kul Jung, Ji Hoon Kim, Hyunggin An, Hyung Joon Yim, Yoon Tae Jeen, Jong Eun Yeon, Do-Sun Lim, Kwan Soo Byun, Yeon Seok Seo
Clin Mol Hepatol 2021;27(3):463-473.
Published online February 15, 2021
DOI: https://doi.org/10.3350/cmh.2020.0351
Background/Aims
Useful biomarkers for metabolic syndrome have been insufficient. We investigated the performance of serum milk fat globule-EGF factor-8 (MFG-E8), the key mediator of inflammatory pathway, in diagnosis of metabolic syndrome.
Methods
Subjects aged between 30 and 64 years were prospectively enrolled in the Seoul Metabolic Syndrome cohort. Serum MFG-E8 levels were measured at baseline.
Results
A total of 556 subjects were included, comprising 279 women (50.2%) and 277 men (49.8%). Metabolic syndrome was diagnosed in 236 subjects (42.4%), and the mean MFG-E8 level of subjects with metabolic syndrome was significantly higher than that of subjects without metabolic syndrome (P<0.001). MFG-E8 level was significantly correlated with all metabolic syndrome components and pulse wave velocity (all P<0.05). Subjects were categorized into two groups according to the best MFG-E8 cut-off value as follows: group 1, MFG-E8 level <4,745.1 pg/mL (n=401, 72.1%); and group 2, MFG-E8 level ≥4,745.1 (n=155, 27.9%). At baseline, metabolic syndrome in group 2 was significantly more prevalent than in group 1 (63.9% vs. 34.2%, P<0.001). During median follow-up of 17 months, metabolic syndrome developed in 122 (38.1%) subjects among 320 subjects without it at baseline. The incidence of metabolic syndrome in group 2 was significantly higher than that in group 1 (55.4% vs. 34.5%, P=0.003). On multivariate analysis, MFG-E8 level ≥4,745.1 pg/mL was an independent predictor for diagnosis and development of metabolic syndrome after adjusting other factors (all P<0.05).
Conclusions
Serum MFG-E8 level is a potent biomarker for the screening and prediction of metabolic syndrome.

Citations

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  • Adipose tissue–derived MFG-E8 promotes hepatic inflammation and fibrosis through macrophage activation in a mouse MASH model
    Masashi Kuroda, Kazuhiro Nomura, Azumi Wada, Yui Hatano, Miki Ogawa, Saya Okamoto, Etsuko Ishikawa, Yuna Izumi-Mishima, Sonoko Yasui-Yamada, Yasuo M. Tsutsumi, Nagakatsu Harada, Rie Tsutsumi, Hiroshi Sakaue
    npj Metabolic Health and Disease.2026;[Epub]     CrossRef
  • Exploring the potential of MFG-E8 in neurodegenerative diseases
    Dan Li, Wang Rongchun, Weihong Lu, Ying Ma
    Critical Reviews in Food Science and Nutrition.2025; 65(28): 5565.     CrossRef
  • Signature gene expression model for quantitative evaluation of MASH-like liver injury in mice
    Volodymyr P. Tryndyak, Rose A. Willett, Zhuolin Song, Kostiantyn Dreval, Jennifer M. Hughes Hanks, Mark I. Avigan, Fred A. Wright, Frederick A. Beland, Ivan Rusyn, Igor P. Pogribny
    Toxicology and Applied Pharmacology.2025; 502: 117442.     CrossRef
  • Elevated circulating HHIP levels in patients with metabolic syndrome
    Jingwei Lei, Yu Yang, Yerui Lai, Dongfang Liu, Cong Wang, Weiwei Xu, Ke Li, Shengbing Li, Mengliu Yang, Ling Li
    Biochemical and Biophysical Research Communications.2024; 736: 150877.     CrossRef
  • MFGE-8 identified in fetal mesenchymal-stromal-cell-derived exosomes ameliorates acute hepatic failure pathology
    Adriana Psaraki, Dimitra Zagoura, Lydia Ntari, Manousos Makridakis, Christina Nikokiraki, Ourania Trohatou, Konstantina Georgila, Christos Karakostas, Ioanna Angelioudaki, Anastasios G. Kriebardis, Roberto Gramignioli, Stratigoula Sakellariou, Maria Xilou
    iScience.2023; 26(11): 108100.     CrossRef
  • Proteomic profiling of serum identifies a molecular signature that correlates with clinical outcomes in COPD
    Rania Dagher, Paul Fogel, Jingya Wang, David Soussan, Chia-Chien Chiang, Jennifer Kearley, Daniel Muthas, Camille Taillé, Patrick Berger, Arnaud Bourdin, Cécile Chenivesse, Sylvie Leroy, Gary Anderson, Alison A. Humbles, Michel Aubier, Roland Kolbeck, Mar
    PLOS ONE.2022; 17(12): e0277357.     CrossRef
  • 11,970 View
  • 189 Download
  • 5 Web of Science
  • Crossref

Editorial

Steatotic liver disease

Probiotics for treatment of nonalcoholic fatty liver disease: It is worth a try
Tian-Yi Ren, Xiao-Yan Li, Jian-Gao Fan
Clin Mol Hepatol 2021;27(1):83-86.
Published online December 3, 2020
DOI: https://doi.org/10.3350/cmh.2020.0298

Citations

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  • Organ cross-talk: molecular mechanisms, biological functions, and therapeutic interventions for diseases
    Huiting Che, Yidan Gao, Yonghu Xu, Hui Xu, Roland Eils, Mei Tian
    Signal Transduction and Targeted Therapy.2026;[Epub]     CrossRef
  • Probiotics as emerging adjuncts in metabolic associated fatty liver disease therapy-a systemic review
    Radha Samyuktha Reddy Narem, Vani Mathakala, Sri Tejaswi Sallabathula, Vijaya Lakshmi Peddiboyina, Uma Maheswari devi Palempalli
    BMC Gastroenterology.2026;[Epub]     CrossRef
  • Lactobacillus plantarum 1-2-3 inhibits ferroptosis by regulating dysregulated fatty acid metabolism to protect mice from high-fat diet-induced MAFLD
    Meihua Zhang, Shuo Zhang, Huixian Wu, Laizhi Xu, Peichao Gao, Yixin Gao, Wentao Fan, Suquan Song
    Free Radical Biology and Medicine.2025; 238: 137.     CrossRef
  • Probiotics as a therapeutic strategy for metabolic dysfunction-associated steatotic liver disease: A systematic review and meta-analysis
    Jing Lu, Xiaoxiao Dong, Ziqi Gao, Huizhen Yan, Dilireba Shataer, Liang Wang, Yanan Qin, Minwei Zhang, Jiayi Wang, Jie Cui, Shengyang Zhou
    Current Research in Food Science.2025; 11: 101138.     CrossRef
  • Metabolic dysfunction-associated steatotic liver disease (MASLD): emerging insights into gut microbiota interactions and therapeutic perspectives
    Wenchu Qian, Ling He, Chenxue Fu, Tiantian Zeng, Hanyu Wang, Haifang Li
    Exploration of Digestive Diseases.2025;[Epub]     CrossRef
  • Gut microbial signatures associated with the Indian lean MASLD phenotype
    Priyankar Dey
    Frontiers in Nutrition.2025;[Epub]     CrossRef
  • The effects of next generation probiotics on metabolic dysfunction-associated steatotic liver disease: a parallel, double-blind, randomized, placebo-controlled trial
    Sung-Min Won, Hyunchae Joung, In Gyu Park, Sang Hak Han, Young Lim Ham, Ji Sook Han, Yoojin Kwon, Dong Joon Kim, Ki Tae Suk
    Journal of Translational Medicine.2025;[Epub]     CrossRef
  • Supplementation of Lactobacillus plantarum ATCC14917 mitigates non-alcoholic fatty liver disease in high-fat-diet-fed rats
    Xingjian Wen, Hejing Liu, Xiaoling Luo, Li Lui, Jiuyu Fan, Yajing Xing, Jia Wang, Xingfang Qiao, Na Li, Guixue Wang
    Frontiers in Microbiology.2023;[Epub]     CrossRef
  • 9,868 View
  • 177 Download
  • 7 Web of Science
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Review

Steatotic liver disease

Application of transient elastography in nonalcoholic fatty liver disease
Xinrong Zhang, Grace Lai-Hung Wong, Vincent Wai-Sun Wong
Clin Mol Hepatol 2020;26(2):128-141.
Published online November 8, 2019
DOI: https://doi.org/10.3350/cmh.2019.0001n
Nonalcoholic fatty liver disease (NAFLD) is currently the most common chronic liver disease worldwide. Although it has become one of the leading causes of cirrhosis and hepatocellular carcinoma in the Western world, the proportion of NAFLD patients developing these complications is rather small. Therefore, current guidelines recommend noninvasive tests for the initial assessment of NAFLD. Among the available non-invasive tests, transient elastography by FibroScan® (Echosens, Paris, France) is commonly used by hepatologists in Europe and Asia, and the machine has been introduced to the United States in 2013 with rapid adoption. Transient elastography measures liver stiffness and the controlled attenuation parameter simultaneously and can serve as a one-stop examination for both liver steatosis and fibrosis. Liver stiffness measurement also correlates with clinical outcomes and can be used to select patients for varices screening. Although obesity is a common reason for measurement failures, the development of the XL probe allows successful measurements in the majority of obese patients. This article reviews the performance and limitations of transient elastography in NAFLD and highlights its clinical applications. We also discuss the reliability criteria for transient elastography examination and factors associated with false-positive liver stiffness measurements.

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  • Correlation of Lipid Profile, LFT, AST/ALT Ratio, BARD, FIB-4, NFS Score, TyG Index with Transient Elastography to Detect Better Noninvasive Marker in Overweight and Obese Patient in Tertiary Care Center, West Bengal: A Cross-Sectional Observational Study
    Ashis Kumar Saha, Puja Mahato, Aritra Kumar Ray, Ipshita Chatterjee, Moyukh Mukherjee
    International Journal of Health Sciences and Research.2026; : 314.     CrossRef
  • Investigating confounding factors in shear wave speed measurements of fibrotic liver tissues: a computer simulation study
    Emily J. Miller, Yongmei M. Jin, Jingfeng Jiang
    Physical and Engineering Sciences in Medicine.2026;[Epub]     CrossRef
  • Metabolic liver imaging: What you need to know
    Luigi Asmundo, Amirkasra Mojtahed, Samay Prakash, Theodore T. Pierce, Jingwei Wei, Angelo Vanzulli
    Digestive and Liver Disease.2026; 58(4): 433.     CrossRef
  • The Association Between Genetic Polymorphism in the Receptor for Advanced Glycation End-Products and Metabolic Dysfunction-Associated Steatotic Liver Disease
    Nourhan Mohammed, Mona M. Hassouna, Mohammed S. Mostafa, Amany E. Elashkar, Eman Abdelsameea, Mary A. Naguib
    Journal of Clinical and Experimental Hepatology.2026; 16(3): 103530.     CrossRef
  • Risk Stratification of a Novel Noninvasive Fibrosis Score in Metabolic Dysfunction-associated Steatotic Liver Disease
    Johnny T.K. Cheung, Xinrong Zhang, Grace Lai-Hung Wong, Terry Cheuk-Fung Yip, Huapeng Lin, Guanlin Li, Howard Ho-Wai Leung, Jimmy Che-To Lai, Sanjiv Mahadeva, Nik Raihan Nik Mustapha, Xiao-Dong Wang, Wen-Yue Liu, Wah-Kheong Chan, Ming-Hua Zheng, Vincent W
    Clinical Gastroenterology and Hepatology.2026;[Epub]     CrossRef
  • The Usefulness of Metformin and Ganwei for Metabolic Dysfunction-Associated Steatotic Liver Disease: A Randomized, Placebo-Controlled Trial
    Chih-Lin Lin, Wei-You Li, Shang-Jung Wu, Patricia M. T. Chen, Allan Y. Chen, Cathy Shen-Jang Fann, Yi-Ming Arthur Chen
    International Journal of Molecular Sciences.2026; 27(5): 2411.     CrossRef
  • Diagnostic performance of ultrasound-derived fat fraction for grading hepatic steatosis in patients with chronic liver diseases: a multicenter study
    Jiahao Han, Lixin Yang, Licheng Chu, Kexin Lou, Qun Zhang, Pingping Wang, Huiming Shen, Jia Li, Zuowei Bao
    European Radiology.2026;[Epub]     CrossRef
  • Head‐to‐Head Comparison of Four Ultrasound Elastography Techniques in Detecting Advanced Fibrosis
    Jiahao Han, Lichen Chu, Lixin Yang, Kexin Lou, Guangbin Dou, Huiming Shen, Xiaojun Cheng, Zuowei Bao, Jia Li
    Portal Hypertension & Cirrhosis.2026;[Epub]     CrossRef
  • Natural disease course of chronic visceral acid sphingomyelinase deficiency in adults: A first step toward treatment criteria
    Eline C. B. Eskes, Laura van Dussen, Marion M. M. G. Brands, Frédéric M. Vaz, Johannes M. F. G. Aerts, André B. P. van Kuilenburg, Barbara Sjouke, Carla E. M. Hollak
    Journal of Inherited Metabolic Disease.2025;[Epub]     CrossRef
  • Risk Stratification of Patients with Metabolic Dysfunction-associated Steatotic Liver Disease: Steatohepatitis, Fibrosis, and Hepatocellular Carcinoma
    Mohamed El-Kassas, Heba A. Othman, Mohamed Elbadry, Khalid Alswat, Yusuf Yilmaz
    Journal of Clinical and Experimental Hepatology.2025; 15(1): 102415.     CrossRef
  • The Loge GDR Was Strongly Associated with NAFLD as a Predictor in Normoalbuminuric Patients with Type 2 Diabetes
    Baolan Ji, Guanqi Gao, Hongyan Zhao, Jie Sheng, Xuan Ma, Shuwei Shi, Bo Ban
    Diabetes, Metabolic Syndrome and Obesity.2025; Volume 18: 115.     CrossRef
  • Diagnostic Accuracy of Non-Invasive Diagnostic Tests for Nonalcoholic Fatty Liver Disease: A Systematic Review and Network Meta-Analysis
    Yuxin Sun, Die Hu, Mingkun Yu, Shi-Bing Liang, Youyou Zheng, Xin Wang, Guangdong Tong
    Clinical Epidemiology.2025; Volume 17: 53.     CrossRef
  • Development of a Fatty Liver Index Based on Real‐World Data
    Wenfeng Ding, Lanlan Liu, Wenjing Lu, Yingli Li, Jing Zhang, Cui Zhang, Yufei Wang, Xueping Ma, Xiaoli Yang
    iLABMED.2025; 3(1): 33.     CrossRef
  • Machine Learning–Based Biomarker Identification for Early Diagnosis of Metabolic Dysfunction–Associated Steatotic Liver Disease
    Jolie Boullion, Amanda Husein, Akshat Agrawal, Diensn Xing, Md Ismail Hossain, Md Shenuarin Bhuiyan, Oren Rom, Steven A Conrad, John A Vanchiere, A Wayne Orr, Christopher G Kevil, Mohammad Alfrad Nobel Bhuiyan
    The Journal of Clinical Endocrinology & Metabolism.2025; 110(11): e3866.     CrossRef
  • Estimated sdLDL-C as a biomarker of hepatic steatosis severity in MASLD: a retrospective study
    Shuo Jiang, Fan Zhang, Hui Yang, Xue Han, Jieru Mao, Guojun Zheng, Yan Fan
    BMC Gastroenterology.2025;[Epub]     CrossRef
  • The value of MR spectroscopy and MR elastography in assessing hepatic involvement of chronic visceral acid sphingomyelinase deficiency in adults
    Eline C.B. Eskes, Sandra A.M. van den Berg-Faaij, Nienke P.M. Wassenaar, Carla E.M. Hollak, Aart J. Nederveen, Barbara Sjouke
    Molecular Genetics and Metabolism.2025; 145(2): 109107.     CrossRef
  • The new definition of metabolic dysfunction-associated steatotic liver disease: the role of ultrasound and elastography
    Xinrui Jin, Terry Cheuk-Fung Yip, Grace Lai-Hung Wong, Vincent Wai-Sun Wong, Jimmy Che-To Lai
    Ultrasonography.2025; 44(3): 189.     CrossRef
  • Prospective Comparison of 2D-Shear Wave Elastography and Vibration-Controlled Transient Elastography in Assessing Liver Fibrosis in Metabolic Dysfunction-Associated Steatotic Liver Disease
    Qingxin Li, Yanhang Gao, Dongxuan Wang, Xiaoxue Zhu, Jing Jia, Lili Liu, Huining Tian, Lishuang Wang, Yingwen Zhang, Dezhi Zhang
    Academic Radiology.2025; 32(9): 5100.     CrossRef
  • Hepatic fibrosis in morbidly obese patients: fibroscan accuracy
    Maged Tharwat Elghannam, Moataz Hassan Hassanien, Ahmed Aly ELRay, Hoda Mohamed Abu-Taleb, Yosry Abdelrahman Ameen, Gamal Mohammed ELattar, Emad Abdelwahab Turky, Mohammed Darwish ELTalkawy
    Exploration of Digestive Diseases.2025;[Epub]     CrossRef
  • Role of liver transient elastography in detecting cirrhosis with esophageal and gastric varices and evaluating variceal severity
    Chaozhi Wang
    BMC Gastroenterology.2025;[Epub]     CrossRef
  • Attenuation Based Quantitative Evaluation of Hepatic Steatosis Using US: Current Status and Future Perspective
    Dong Ho Lee
    Journal of the Korean Society of Radiology.2025; 86(3): 321.     CrossRef
  • Perturbation solution for second-harmonic generation in focused shear wave beams in soft solids
    Philip G. Kaufinger, John M. Cormack, Kyle S. Spratt, Mark F. Hamilton
    Wave Motion.2025; 139: 103595.     CrossRef
  • Prevalence of Hepatic Steatosis and Fibrosis in Asian Indian Individuals with Type 2 Diabetes
    Khandhulwa Chandramouli Bhuvanesswar, Brijendra Kumar Srivastava, Anandakumar Amutha, Varun Damle, Aswin Krishna, Prasanna Kumar Gupta, Phillips Routray, Dhanasekaran Killivalavan, Saravanan Jebarani, Ulagamathesan Venkatesan, Rosette James Chakkalakal,
    Diabetes Therapy.2025; 16(9): 1797.     CrossRef
  • Circulating microRNAs as potential non-invasive biomarkers for diagnosis and severity assessment of Metabolic Dysfunction-Associated Steatotic Liver Disease: a case–control study
    Hanan M Nafeh, Nourhan M Abbas, Mohamed A El-Mokhtar, Hebatallah M. Hassan, Sahar M Hassany
    The Egyptian Journal of Internal Medicine.2025;[Epub]     CrossRef
  • Impact of genotyping (PTPN2, rs2542151) and (MBOAT7, rs641738) in prediction of fibrosis in Metabolic dysfunction- associated steatotic liver disease’ patients
    Shimaa Abdelsattar, Hiba S. Al-Amodi, Hala F. M. Kamel, Zeinab A. Kasemy, Ehab Darwish, Asmaa Mosbeh, Ayman A. Sakr, Hanaa M. Elgazzar, Mervat Abdelkareem, Mai Abozeid, Shimaa K. Zewain, Hanan M. Bedair, Sabry M. Abdelmageed
    Frontiers in Endocrinology.2025;[Epub]     CrossRef
  • Long-Term Feasibility and Outcomes of a Digital Health Program to Improve Liver Fat and Cardiometabolic Markers in Individuals With Nonalcoholic Fatty Liver Disease: Prospective Single-Arm Feasibility Study
    Sigridur Björnsdottir, Hildigunnur Ulfsdottir, Elias Freyr Gudmundsson, Bartosz Dobies, Kolbrun Sveinsdottir, Ari Pall Isberg, Gudlaug E A Magnusdottir, Thrudur Gunnarsdottir, Tekla Karlsdottir, Gudlaug Bjornsdottir, Sigurdur Sigurdsson, Saemundur Oddsson
    JMIR Cardio.2025; 9: e72074.     CrossRef
  • DC09, Derivative of 3‐(2‐hydroxy‐5‐methoxyphenyl)‐1‐(5‐methylfuran‐2‐yl)prop‐2‐en‐1‐one Attenuates Nonalcoholic Fatty Liver Disease by Targeting PI3K/Akt Pathway: Insights From In‐Vivo Zebrafish Model and In‐Vitro HepG2 Cell
    Santhanam Sanjai Dharshan, B. Haridevamuthu, Karthikeyan Ramamurthy, B. Aswinanand, Dhivya Loganathan Sumathi, Ilavenil Soundharrajan, Mansour K. Gatasheh, S. Karthick Raja Namasivayam, Kathiravan Muthu Kumaradoss, Jesu Arockiaraj
    Journal of Biochemical and Molecular Toxicology.2025;[Epub]     CrossRef
  • Current Update on Nomenclature, Diagnosis, and Management of Metabolic Dysfunction–associated Steatotic Liver Disease: Radiologists’ Perspective
    Eri G. Osta, Florentino Saenz Rios, Sriram Jaganathan, Courtney Thomas, Eugenia Tsai, Venkateswar Surabhi, Srinivasa R. Prasad, Venkata S. Katabathina
    RadioGraphics.2025;[Epub]     CrossRef
  • Hepatic steatosis/fibrosis related biomarkers in patients with metabolic dysfunction-associated steatotic liver disease
    Zhi Peng, Zijin Wang, Juan Wang, Xuefeng Li
    Biomarkers in Medicine.2025; 19(23): 1239.     CrossRef
  • Fibrotic Burden in Patients With Hepatitis B Virus–Related Cirrhosis Is Independently Associated With Poorer Kidney Outcomes
    Chan-Young Jung, Hui-Yun Jung, Hyung Woo Kim, Geun Woo Ryu, Jung Il Lee, Sang Hoon Ahn, Seung Up Kim, Beom Seok Kim
    The Journal of Infectious Diseases.2024; 229(1): 108.     CrossRef
  • User Engagement, Acceptability, and Clinical Markers in a Digital Health Program for Nonalcoholic Fatty Liver Disease: Prospective, Single-Arm Feasibility Study
    Sigridur Björnsdottir, Hildigunnur Ulfsdottir, Elias Freyr Gudmundsson, Kolbrun Sveinsdottir, Ari Pall Isberg, Bartosz Dobies, Gudlaug Erla Akerlie Magnusdottir, Thrudur Gunnarsdottir, Tekla Karlsdottir, Gudlaug Bjornsdottir, Sigurdur Sigurdsson, Saemundu
    JMIR Cardio.2024; 8: e52576.     CrossRef
  • Focused Shear Wave Beam Propagation in Tissue-Mimicking Phantoms
    John M. Cormack, Yu-hsuan Chao, Branch T. Archer, Kang Kim, Kyle S. Spratt, Mark F. Hamilton
    IEEE Transactions on Biomedical Engineering.2024; 71(2): 621.     CrossRef
  • Development of Cost-Effective Fatty Liver Disease Prediction Models in a Chinese Population: Statistical and Machine Learning Approaches
    Liang Zhang, Yueqing Huang, Min Huang, Chun-Hua Zhao, Yan-Jun Zhang, Yi Wang
    JMIR Formative Research.2024; 8: e53654.     CrossRef
  • Exploring the link: magnesium intake and hepatic steatosis in Americans
    Xingxing Chen, Liying Fu, Zhongxin Zhu, Yunchao Wang
    Frontiers in Nutrition.2024;[Epub]     CrossRef
  • The associations between fibrosis changes and liver‐related events in patients with metabolic dysfunction‐associated steatotic liver disease
    Hye Won Lee, Kun Hee Kim, Sang Hoon Ahn, Han Chu Lee, Jonggi Choi
    Liver International.2024; 44(6): 1448.     CrossRef
  • A Prospective Randomised Comparative Four-arm Intervention Study of Efficacy and Safety of Saroglitazar and Vitamin E in Patients With Non-alcoholic Fatty Liver Disease (NAFLD)/Non-alcoholic Steatohepatitis (NASH)-SVIN TRIAL
    Bilal A. Mir, Brij Sharma, Rajesh Sharma, Vishal Bodh, Ashish Chauhan, Tahir Majeed, Inaamul Haq, Neetu Sharma, Dikshant Sharma
    Journal of Clinical and Experimental Hepatology.2024; 14(5): 101398.     CrossRef
  • Comparative value of controlled attenuation (CAPc) and continuous controlled attenuation (CAP) parameters for different stages of non-alcoholic fatty liver disease
    A. A. Goncharov, A. N. Sasunova, V. A. Isakov
    Experimental and Clinical Gastroenterology.2024; (2): 55.     CrossRef
  • Exploring the association between dietary fiber intake and hepatic steatosis: insights from NHANES
    Xingxing Chen, Liying Fu, Zhongxin Zhu, Yunchao Wang
    BMC Gastroenterology.2024;[Epub]     CrossRef
  • Appendicular Skeletal Muscle Mass to Visceral Fat Area Ratio Predicts Hepatic Morbidities
    Eugene Han, Yong-ho Lee, Sang Hoon Ahn, Bong-Soo Cha, Seung Up Kim, Byung-Wan Lee
    Gut and Liver.2024; 18(3): 509.     CrossRef
  • Associations between allostatic load and hepatic steatosis and liver fibrosis: evidence from NHANES 2017–2020
    Zhikun Dai, Xiaohui Zhou
    BMC Public Health.2024;[Epub]     CrossRef
  • NAFLD (MASLD)/NASH (MASH): Does It Bother to Label at All? A Comprehensive Narrative Review
    Consolato M. Sergi
    International Journal of Molecular Sciences.2024; 25(15): 8462.     CrossRef
  • Agile 3+ and Agile 4 scores predict chronic kidney disease development in metabolic dysfunction‐associated steatotic liver disease
    Chan‐Young Jung, Jung Il Lee, Sang Hoon Ahn, Seung Up Kim, Beom Seok Kim
    Alimentary Pharmacology & Therapeutics.2024; 60(8): 1051.     CrossRef
  • Electrical and Viscoelastic Parameters of Erythrocytes as a Part of Diagnostic Models for Differentiating Fatty Liver Disease of Mixed Genesis from Non-Alcoholic and Alcohol-Related Fatty Liver Disease
    M. V. Kruchinina, M. F. Osipenko, M. V. Parulikova, A. A. Gromov
    Russian Journal of Gastroenterology, Hepatology, Coloproctology.2024; 34(3): 38.     CrossRef
  • Diagnostic models for differentiating fatty liver disease of alcohol and non-alcoholic genesis
    M. V. Kruchinina, M. F. Osipenko, M. V. Parulikova, A. V. Belkovets, E. V. Kruchinina
    Meditsinskiy sovet = Medical Council.2024; (15): 80.     CrossRef
  • Metabolic dysfunction-associated steatotic liver disease: The question of long-term high-normal alanine aminotransferase as a screening test
    Terence N Moyana
    World Journal of Gastroenterology.2024; 30(42): 4576.     CrossRef
  • Liver fibrosis as a barometer of systemic health by gauging the risk of extrahepatic disease
    Amedeo Lonardo, Stefano Ballestri, Gyorgy Baffy, Ralf Weiskirchen
    Metabolism and Target Organ Damage.2024;[Epub]     CrossRef
  • Prevalence of Liver Steatosis Among Workers in Ouagadougou and Associated Factors: A Cross‐Sectional Study
    Delphine Napon‐Zongo, Jeoffray Diendere, Armel M. Sanou, Abou Coulibaly, Abdoulaye Dera, Nina G. M. Ouattara, Augustin N. Zeba, Seni Kouanda
    JGH Open.2024;[Epub]     CrossRef
  • Metabolic dysfunction-associated fatty liver disease: bridging cardiology and hepatology
    Xiao-Dong Zhou, Giovanni Targher, Christopher D. Byrne, Michael D. Shapiro, Li-Li Chen, Ming-Hua Zheng
    Cardiology Plus.2024; 9(4): 275.     CrossRef
  • Жирные кислоты мембран эритроцитов как биомаркеры неалкогольной жировой болезни печени у мужчин
    М. В. Кручинина, М. В. Паруликова, Н. Е. Першина, Э. В. Кручинина
    Ateroscleroz.2023; 18(4): 362.     CrossRef
  • Prevalence of at-risk NASH and its association with metabolic syndrome in US adults with NAFLD, 2017–2018
    Julia Y. Payne, Naim Alkhouri, Phuc Le, Michael B. Rothberg, Prido Polanco, Celine Sakkal, Srinivasan Dasarathy
    Hepatology Communications.2023; 7(1): e0019.     CrossRef
  • Metabolic Profile Reflects Stages of Fibrosis in Patients with Non-Alcoholic Fatty Liver Disease
    Nila Jambulingam, Roberta Forlano, Benjamin Preston, Benjamin H. Mullish, Greta Portone, Yama Baheer, Michael Yee, Robert D. Goldin, Mark R. Thursz, Pinelopi Manousou
    International Journal of Molecular Sciences.2023; 24(4): 3563.     CrossRef
  • Special Population
    Ajay Duseja, Arka De, Vincent Wong
    Clinics in Liver Disease.2023; 27(2): 451.     CrossRef
  • How many times should we repeat measurements of the ultrasound-guided attenuation parameter for evaluating hepatic steatosis?
    Duck Min Seo, Sang Min Lee, Ji Won Park, Min-Jeong Kim, Hong Il Ha, Sun-Young Park, Kwanseop Lee
    Ultrasonography.2023; 42(2): 227.     CrossRef
  • Noninvasive risk assessment of hepatic decompensation in patients with hepatitis B virus‐related liver cirrhosis
    David Sooik Kim, Beom Kyung Kim, Jae Seung Lee, Hye Won Lee, Jun Yong Park, Do Young Kim, Sang Hoon Ahn, Nikolaos Pyrsopoulos, Seung Up Kim
    Journal of Gastroenterology and Hepatology.2023; 38(8): 1372.     CrossRef
  • Effect of fish oil supplementation on the concentration of miRNA-122, FGF-21 and liver fibrosis in patients with NAFLD: Study protocol for a randomized, double-blind and placebo-controlled clinical trial
    Lygia N. Barroso, Jessica Salarini, Nathalie Carvalho Leite, Cristiane A. Villela-Nogueira, Alberto Dávalos, Maria das Graças Tavares Carmo, Wilza Arantes Ferreira Peres
    Clinical Nutrition ESPEN.2023; 57: 117.     CrossRef
  • B-mode shear wave elastography can be an alternative method to vibration-controlled transient elastography according to a moderate-scale population study
    Masashi Hirooka, Yohei Koizumi, Yoshiko Nakamura, Ryo Yano, Kana Hirooka, Makoto Morita, Yusuke Imai, Yoshio Tokumoto, Masanori Abe, Yoichi Hiasa
    Journal of Medical Ultrasonics.2023; 50(4): 473.     CrossRef
  • Advanced liver fibrosis predicts heart failure and hospitalizations in people with type 2 diabetes: A prospective cohort study from Hong Kong Diabetes Register
    Alice Pik-Shan Kong, Eric Siu-Him Lau, Chun-Kwan O, Andrea On-Yan Luk, Terry Cheuk-Fung Yip, Elaine Yee-Kwan Chow, Raymond Kwok, Hye Won Lee, Grace Lai-Hung Wong, Ronald Ching-Wan Ma, Henry Lik-Yuen Chan, Vincent Wai-Sun Wong, Juliana Chung-Ngor Chan
    Diabetes Research and Clinical Practice.2023; 202: 110825.     CrossRef
  • Clinical impact of hepatic steatosis on chronic hepatitis B patients in Asia: A systematic review and meta‐analysis
    Run Zhou, Luping Yang, Binbin Zhang, Yunpeng Gu, Tingting Kong, Wei Zhang, Lei Sun, Chunlan Liu, Ningjia Kong, Jie Li, Junping Shi
    Journal of Viral Hepatitis.2023; 30(10): 793.     CrossRef
  • Analysis of clinical features and identification of risk factors in patients with non-alcoholic fatty liver disease based on FibroTouch
    Yan Liao, Lei Liu, Jiayao Yang, Xiaoli Zhou, Xiaoli Teng, Yixi Li, Ying Wan, Jian Yang, Zhaohong Shi
    Scientific Reports.2023;[Epub]     CrossRef
  • MAFLD fibrosis score: Using routine measures to identify advanced fibrosis in metabolic‐associated fatty liver disease
    Johnny T. K. Cheung, Xinrong Zhang, Grace Lai‐Hung Wong, Terry Cheuk‐Fung Yip, Huapeng Lin, Guanlin Li, Howard Ho‐Wai Leung, Jimmy Che‐To Lai, Sanjiv Mahadeva, Nik Raihan Nik Mustapha, Xiao‐Dong Wang, Wen‐Yue Liu, Vincent Wai‐Sun Wong, Wah‐Kheong Chan, Mi
    Alimentary Pharmacology & Therapeutics.2023; 58(11-12): 1194.     CrossRef
  • Use of a controlled attenuation parameter for the diagnosis of non-alcoholic fatty liver disease
    Alexey A. Goncharov, Armida N. Sasunova, Vladimir I. Pilipenko, Vasily A. Isakov
    Terapevticheskii arkhiv.2023; 95(8): 641.     CrossRef
  • Duration of type 2 diabetes and liver-related events in nonalcoholic fatty liver disease: A landmark analysis
    Xinrong Zhang, Terry Cheuk-Fung Yip, Yee-Kit Tse, Vicki Wing-Ki Hui, Guanlin Li, Huapeng Lin, Lilian Yan Liang, Jimmy Che-To Lai, Henry Lik-Yuen Chan, Stephen Lam Chan, Alice Pik-Shan Kong, Grace Lai-Hung Wong, Vincent Wai-Sun Wong
    Hepatology.2023; 78(6): 1816.     CrossRef
  • Low Relative Handgrip Strength Is Associated with a High Risk of Non-Alcoholic Fatty Liver Disease in Italian Adults: A Retrospective Cohort Study
    Samantha Maurotti, Roberta Pujia, Elisa Mazza, Maria Francesca Pileggi, Franco Arturi, Maria Grazia Tarsitano, Tiziana Montalcini, Arturo Pujia, Yvelise Ferro
    Applied Sciences.2023; 13(22): 12489.     CrossRef
  • Non-Invasive Diagnostic of NAFLD in Type 2 Diabetes Mellitus and Risk Stratification: Strengths and Limitations
    Alina Boeriu, Daniela Dobru, Crina Fofiu
    Life.2023; 13(12): 2262.     CrossRef
  • Non-alcoholic fatty liver disease in obese subjects as related to increasing insulin resistance and deteriorating glucose control: Three years of follow-up from a longitudinal survey
    Thomas Forst, Isabel Botz, Matthias Berse, Stephan Voswinkel, Mares-Elaine Strempler, Sybille Baumann, Maria Marinez
    Journal of Diabetes & Metabolic Disorders.2023; 23(1): 999.     CrossRef
  • Noninvasive tests for liver fibrosis in 2024: are there different scales for different diseases?
    Jimmy Che-To Lai, Lilian Yan Liang, Grace Lai-Hung Wong
    Gastroenterology Report.2023;[Epub]     CrossRef
  • Advanced liver fibrosis measured by transient elastography predicts chronic kidney disease development in individuals with non-alcoholic fatty liver disease
    Chan-Young Jung, Geun Woo Ryu, Hyung Woo Kim, Sang Hoon Ahn, Seung Up Kim, Beom Seok Kim
    Diabetologia.2022; 65(3): 518.     CrossRef
  • Diagnostic Performance of 2-D Shear Wave Elastography on the Evaluation of Hepatic Fibrosis with Emphasis on Impact of the Different Region-of-Interest Methods
    Eun Mi Kim, Ji-Won Park, Sang Min Lee, Min-Jeong Kim, Hong Il Ha, Sung-Eun Kim, Eun Soo Kim, Young Chul Kim, Kwanseop Lee
    Ultrasound in Medicine & Biology.2022; 48(2): 198.     CrossRef
  • Cross-talk between non-alcoholic fatty liver disease and cardiovascular disease: implications for future trial design
    Pierpaolo Pellicori, Muthiah Vaduganathan, João Pedro Ferreira, Faiez Zannad, Arun J. Sanyal
    Diabetes & Metabolism.2022; 48(2): 101281.     CrossRef
  • Controlled attenuation parameter measured using transient elastography for the noninvasive assessment of macrovesicular steatosis in potential living liver donors
    Sunyoung Lee, Kyoung Won Kim, So Yeon Kim, Nieun Seo, Gi-Won Song, Sung-Gyu Lee
    Ultrasonography.2022; 41(1): 164.     CrossRef
  • Transient Elastography–Assessed Hepatic Steatosis and Fibrosis Are Associated With Body Composition in the United States
    Aynur Unalp-Arida, Constance E. Ruhl
    Clinical Gastroenterology and Hepatology.2022; 20(4): e808.     CrossRef
  • Non-invasive tests of non-alcoholic fatty liver disease
    Guanlin Li, Xinrong Zhang, Huapeng Lin, Lilian Yan Liang, Grace Lai-Hung Wong, Vincent Wai-Sun Wong
    Chinese Medical Journal.2022; 135(5): 532.     CrossRef
  • Comparison of FibroScan-Aspartate Aminotransferase (FAST) Score and Other Non-invasive Surrogates in Predicting High-Risk Non-alcoholic Steatohepatitis Criteria
    Jae Seung Lee, Hye Won Lee, Beom Kyung Kim, Jun Yong Park, Do Young Kim, Sang Hoon Ahn, Jae Young Jang, Soo Young Park, Hyun Woong Lee, Chun Kyon Lee, Seung Up Kim
    Frontiers in Medicine.2022;[Epub]     CrossRef
  • Association Between Skeletal Muscle Mass and Severity of Steatosis and Fibrosis in Non-alcoholic Fatty Liver Disease
    Wen Guo, Xin Zhao, Mengyuan Miao, Xiuru Liang, Xiaona Li, Pei Qin, Jing Lu, Wenfang Zhu, Juan Wu, Chen Zhu, Nianzhen Xu, Qun Zhang
    Frontiers in Nutrition.2022;[Epub]     CrossRef
  • Vibration-controlled Transient Elastography in NAFLD: Review Study
    Hasan Ozkan, Abdullah M Ozercan
    Euroasian Journal of Hepato-Gastroenterology.2022; 12(S1): S41.     CrossRef
  • Magnetic resonance imaging improves stratification of fibrosis and steatosis in patients with chronic liver disease
    Han Ah Lee, Seung-seob Kim, Jin-Young Choi, Yeon Seok Seo, Beom Jin Park, Ki Choon Sim, Seung Up Kim
    Abdominal Radiology.2022; 47(11): 3733.     CrossRef
  • DETERMINANTS OF SIGNIFICANT HEPATIC FIBROSIS IN TYPE 2 DIABETES PATIENTS WITH NON-ALCOHOLIC FATTY LIVER DISEASE IN SOUTH INDIA.
    A V Ramya, P Thirumal
    INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH.2022; : 24.     CrossRef
  • Pulse-Echo Quantitative US Biomarkers for Liver Steatosis: Toward Technical Standardization
    David T. Fetzer, Ivan M. Rosado-Mendez, Michael Wang, Michelle L. Robbin, Arinc Ozturk, Keith A. Wear, Juvenal Ormachea, Timothy A. Stiles, J. Brian Fowlkes, Timothy J. Hall, Anthony E. Samir
    Radiology.2022; 305(2): 265.     CrossRef
  • The triglyceride glucose-body mass index: a non-invasive index that identifies non-alcoholic fatty liver disease in the general Japanese population
    Haofei Hu, Yong Han, Changchun Cao, Yongcheng He
    Journal of Translational Medicine.2022;[Epub]     CrossRef
  • Myocyte Enhancer Factor 2A Contributes to the TGF-β1-Mediated Cholangiocyte Epithelial to Mesenchymal Transition and Senescence in Cholestatic Liver Fibrosis
    Guangxi Zhou, Fei Hou, Heng He, Yuan Xue, Yibo Wang, Xueying Chen, Fengqin Zhu
    Frontiers in Bioscience-Landmark.2022;[Epub]     CrossRef
  • Clinical Feasibility of Quantitative Ultrasound Imaging for Suspected Hepatic Steatosis: Intra- and Inter-examiner Reliability and Correlation with Controlled Attenuation Parameter
    Sun Kyung Jeon, Jeong Min Lee, Ijin Joo
    Ultrasound in Medicine & Biology.2021; 47(3): 438.     CrossRef
  • Updates in the quantitative assessment of liver fibrosis for nonalcoholic fatty liver disease: Histological perspective
    Gwyneth Soon, Aileen Wee
    Clinical and Molecular Hepatology.2021; 27(1): 44.     CrossRef
  • Noninvasive evaluation of liver fibrosis: comparison of the stretched exponential diffusion-weighted model to other diffusion-weighted MRI models and transient elastography
    Jae Hyon Park, Nieun Seo, Yong Eun Chung, Seung Up Kim, Yung Nyun Park, Jin-Young Choi, Mi-Suk Park, Myeong-Jin Kim
    European Radiology.2021; 31(7): 4813.     CrossRef
  • Screening for undiagnosed non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH): A population-based risk factor assessment using vibration controlled transient elastography (VCTE)
    Wayne Eskridge, John M. Vierling, Wayne Gosbee, Gabriella A. Wan, May-Linh Hyunh, Henry E. Chang, Daisuke Tokuhara
    PLOS ONE.2021; 16(11): e0260320.     CrossRef
  • A prospective 5-year study on the use of transient elastography to monitor the improvement of non-alcoholic fatty liver disease following bariatric surgery
    Shirley Yuk-Wah Liu, Vincent Wai-Sun Wong, Simon Kin-Hung Wong, Grace Lai-Hung Wong, Carol Man-sze Lai, Candice Chuen-Hing Lam, Sally She-Ting Shu, Henry Lik-Yuen Chan, Enders Kwok-Wai Ng
    Scientific Reports.2021;[Epub]     CrossRef
  • Ultrasound Elastography in Liver Tissue: Current Status
    Zhang, MD Mingzhu, Ding, MD Zhaoyan, Niu, MD Xiaoyan, Gao, MD Yuxiu, Zhao, MD Cheng
    ADVANCED ULTRASOUND IN DIAGNOSIS AND THERAPY.2021; 5(3): 197.     CrossRef
  • Magnetic Resonance Spectroscopy of Hepatic Fat from Fundamental to Clinical Applications
    Duanghathai Pasanta, Khin Thandar Htun, Jie Pan, Montree Tungjai, Siriprapa Kaewjaeng, Hongjoo Kim, Jakrapong Kaewkhao, Suchart Kothan
    Diagnostics.2021; 11(5): 842.     CrossRef
  • Current and Emerging Biomarkers and Imaging Modalities for Nonalcoholic Fatty Liver Disease: Clinical and Research Applications
    T. Hydes, E. Brown, A. Hamid, A.C. Bateman, D.J. Cuthbertson
    Clinical Therapeutics.2021; 43(9): 1505.     CrossRef
  • Non-alcoholic fatty liver disease in adults: clinic, diagnostics, treatment. Guidelines for therapists, third version
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Original Articles

Viral hepatitis

Association between hepatic steatosis and the development of hepatocellular carcinoma in patients with chronic hepatitis B
Yun Bin Lee, Yeonjung Ha, Young Eun Chon, Mi Na Kim, Joo Ho Lee, Hana Park, Kwang-il Kim, Soo-Hwan Kim, Kyu Sung Rim, Seong Gyu Hwang
Clin Mol Hepatol 2019;25(1):52-64.
Published online October 23, 2018
DOI: https://doi.org/10.3350/cmh.2018.0040
Background/Aims
Nonalcoholic fatty liver disease (NAFLD) is becoming a worldwide epidemic, and is frequently found in patients with chronic hepatitis B (CHB). We investigated the impact of histologically proven hepatic steatosis on the risk for hepatocellular carcinoma (HCC) in CHB patients without excessive alcohol intake.
Methods
Consecutive CHB patients who underwent liver biopsy from January 2007 to December 2015 were included. The association between hepatic steatosis (≥ 5%) and subsequent HCC risk was analyzed. Inverse probability weighting (IPW) using the propensity score was applied to adjust for differences in patient characteristics, including metabolic factors.
Results
Fatty liver was histologically proven in 70 patients (21.8%) among a total of 321 patients. During the median (interquartile range) follow-up of 5.3 (2.9–8.3) years, 17 of 321 patients (5.3%) developed HCC: 8 of 70 patients (11.4%) with fatty liver and 9 of 251 patients (3.6%) without fatty liver. The five-year cumulative incidences of HCC among patients without and with fatty liver were 1.9% and 8.2%, respectively (P=0.004). Coexisting fatty liver was associated with a higher risk for HCC (adjusted hazards ratio [HR], 3.005; 95% confidence interval [CI], 1.122–8.051; P=0.03). After balancing with IPW, HCC incidences were not significantly different between the groups (P=0.19), and the association between fatty liver and HCC was not significant (adjusted HR, 1.709; 95% CI, 0.404–7.228; P=0.47).
Conclusions
Superimposed NAFLD was associated with a higher HCC risk in CHB patients. However, the association between steatosis per se and HCC risk was not evident after adjustment for metabolic factors.

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  • Antiviral Therapy Reduces Hepatocellular Carcinoma and Cirrhosis Risk in Chinese Chronic Hepatitis B Patients With Mildly Elevated Alanine Aminotransferase
    Jian Wang, Zhiyi Zhang, Li Zhu, Tao Fan, Ye Xiong, Shaoqiu Zhang, Chao Jiang, Shengxia Yin, Xin Tong, Juan Xia, Xiaomin Yan, Renling Yao, Yu Shi, Xingxiang Liu, Chuanwu Zhu, Chao Wu, Rui Huang
    Clinical Gastroenterology and Hepatology.2026;[Epub]     CrossRef
  • Steatosis paradox: Unraveling pathways of suppressive effect of hepatic steatosis on hepatitis B virus
    Shang-Chin Huang, Jia-Horng Kao
    Biomedical Journal.2026; 49(3): 100969.     CrossRef
  • Treatment strategies for patients with hepatitis B virus infection coexisting with hepatitis C virus or metabolic dysfunction-associated steatotic liver disease
    Chieh Liu, Yi-Fen Shih, Chun-Jen Liu
    Clinical and Molecular Hepatology.2026; 32(2): 565.     CrossRef
  • The Chronic Hepatitis B and Metabolic Dysfunction-Associated Steatotic Liver Disease Paradox: Friend or Foe?
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    Gut and Liver.2026; 20(3): 350.     CrossRef
  • High serum growth differentiation factor 15 is a risk factor for the occurrence of hepatocellular carcinoma in chronic hepatitis B patients treated with nucleos(t)ide analogs
    Emi Sometani, Hayato Hikita, Kazuhiro Murai, Hidenori Toyoda, Satoshi Tanaka, Tsugiko Oze, Jihyun Sung, Akiyoshi Shimoda, Makoto Fukuoka, Satoshi Shigeno, Keisuke Fukutomi, Kumiko Shirai, Yuki Tahata, Yoshinobu Saito, Akira Nishio, Kunimaro Furuta, Takahi
    Hepatology Research.2025; 55(1): 22.     CrossRef
  • Risk Stratification of Metabolic Risk Factors and Statin Use Associated With Liver and Nonliver Outcomes in Chronic Hepatitis B
    Xinrong Zhang, Vy H Nguyen, Leslie Yeeman Kam, Scott D Barnett, Linda Henry, Ramsey Cheung, Mindie H Nguyen
    The Journal of Infectious Diseases.2025; 231(4): 1079.     CrossRef
  • Coexisting steatotic liver disease is not associated with long-term liver-related events in patients with chronic hepatitis B
    Navavee Uman, Apichat Kaewdech, Pimsiri Sripongpun, Naichaya Chamroonkul, Teerha Piratvisuth
    Gastroenterology Report.2025;[Epub]     CrossRef
  • Association of concomitant MASLD and hepatitis B virus with clinical prognosis in hepatocellular carcinoma after curative resection
    Chih-Jan Ko
    American Journal of Cancer Research.2025; 15(2): 737.     CrossRef
  • Study on Ultrasound-Assisted Diagnosis of CHB Complicated with NAFLD Hepatic Fibrosis Based on Deep Learning
    Xiuling Huang, Shan Huang, Changfeng Dong, Nuo Chen, Yuxuan Wang, Changmiao Wang, Yongquan Zhang, Cheng Feng
    Journal of Imaging Informatics in Medicine.2025; 38(6): 4349.     CrossRef
  • The outcomes and mechanisms of chronic hepatitis B complicated by metabolic dysfunction-associated steatotic liver disease
    Mao-Ping Li, Kai-Zhong Luo
    Hepatobiliary & Pancreatic Diseases International.2025; 24(5): 476.     CrossRef
  • Impact of Metabolic Dysfunction-Associated Fatty Liver Disease of Varying Severity on Antiviral Treatment Outcomes and Clinical Prognosis in Patients with Chronic Hepatitis B: A Systematic Review and Meta-analysis
    Qianqian Zhu, Chengde Su, Mingdan Li, Yali Xu, Qian Liu, Ying Zhang, Xinyi Zhang, Qiuxiang Li, Huajun Wang, Yawen Luo, Ping Yang
    Infectious Diseases and Therapy.2025; 14(8): 1599.     CrossRef
  • Chronic hepatitis B: Is it time for expanded antiviral treatment?
    Manish Manrai, Atul A Jha, Aditya V Pachisia, Saurabh Dawra
    World Journal of Virology.2025;[Epub]     CrossRef
  • Hepatocellular carcinoma risk stratification to identify patients suitable for intensive surveillance in viral hepatitis: the SELECT score
    Yeun-Yoon Kim, Won Chang, Jeong Min Lee, Se Woo Kim, Jae Seok Bae, Jeongin Yoo, Sun Kyung Jeon, HeeSoo Kim, Young Hoon Kim, Jin-Young Choi, Eun Ju Cho, Yun Bin Lee, Sook-Hyang Jeong, Do Young Kim, Yunhee Choi, Jeong Hee Yoon
    European Radiology.2025; 36(4): 2929.     CrossRef
  • Influence of metabolic dysfunction-associated fatty liver disease on the prognosis of patients with HBV-related acute-on-chronic liver failure
    Rui-Min Lai, Li-Xi Yao, Shan Lin, Jia-Hui Zhou, Bing-Ping Liu, Zhao-Yi Liang, Tianbin Chen, Jia-Ji Jiang, Qi Zheng, Yueyong Zhu
    Expert Review of Gastroenterology & Hepatology.2024; 18(1-3): 103.     CrossRef
  • Review on article of effects of tenofovir alafenamide and entecavir in chronic hepatitis B virus patients
    Yu-Tong Sun, Qian-Qian Chen
    World Journal of Hepatology.2024; 16(1): 109.     CrossRef
  • Effect of metabolic dysfunction‑associated fatty liver disease on the risk of hepatocellular carcinoma in patients with chronic hepatitis B: A systematic review and meta‑analysis
    Sixing Shen, Lingyan Pan
    Experimental and Therapeutic Medicine.2024;[Epub]     CrossRef
  • Effect of Concurrent Metabolic Dysfunction-Associated Steatotic Liver Disease on Serial Non-invasive Fibrosis Markers in Chronic Hepatitis B
    Danny Con, Steven Tu, Daniel Clayton-Chubb, John S. Lubel, Amanda J. Nicoll, Rohit Sawhney, Stephen Bloom
    Digestive Diseases and Sciences.2024; 69(4): 1496.     CrossRef
  • Influence of nonalcoholic fatty liver disease on response to antiviral treatment in patients with chronic hepatitis B: A meta-analysis
    Shi-Yi Liu, Dian Wang, Jing Liu, Lu-Ping Yang, Gong-Ying Chen
    World Journal of Hepatology.2024; 16(3): 465.     CrossRef
  • Navigating the Nomenclature of Liver Steatosis: Transitioning from NAFLD to MAFLD and MASLD - Understanding Affinities and Differences
    Apichat Kaewdech, Pimsiri Sripongpun
    Siriraj Medical Journal.2024; 76(4): 234.     CrossRef
  • Nonalcoholic fatty liver disease in Sub-Saharan Africa: A descriptive study of the range of histopathological findings in the South-West zone of Nigeria
    Olusegun Sylvester Ojo, Olusegun Adekanle, Dennis Ndububa, Olawunmi Kolawole, Omolade Adefolabi Betiku
    Nigerian Journal of Gastroenterology and Hepatology.2024; 16(1): 42.     CrossRef
  • Hepatic macrophage niche: a bridge between HBV-mediated metabolic changes with intrahepatic inflammation
    Jun Wang, Hongzhou Lu, Qian Li
    Frontiers in Immunology.2024;[Epub]     CrossRef
  • Prevalence of nonalcoholic fatty liver disease in patients with hepatitis B: A meta-analysis
    Li Zhang, Hong-Di Wu, Yuan-Fang Qian, Hong-Yan Xu
    World Journal of Clinical Cases.2024; 12(25): 5749.     CrossRef
  • Chronic hepatitis B and metabolic dysfunction-associated steatotic liver disease: Metabolic risk factors are key drivers of hepatocellular carcinoma
    Gupse Adali, Huseyin Aykut, Nermin Mutlu Bilgic, Yusuf Yilmaz
    Heliyon.2024; 10(18): e37990.     CrossRef
  • Revolutionizing the understanding of liver disease: Metabolism, function and future
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    World Journal of Hepatology.2024; 16(12): 1365.     CrossRef
  • Hepatic steatosis: Ultrasound assessment using attenuation imaging (ATI) with liver biopsy correlation
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    Journal of Medical Imaging and Radiation Oncology.2023; 67(1): 45.     CrossRef
  • Concomitant Diseases and Co-contribution on Progression of Liver Stiffness in Patients with Hepatitis B Virus Infection
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    Digestive Diseases and Sciences.2023; 68(4): 1605.     CrossRef
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    Journal of Medical Virology.2023;[Epub]     CrossRef
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    Hepatology.2023; 77(5): 1735.     CrossRef
  • Letter: metabolic dysfunction‐associated fatty liver disease increases risk of all‐cause mortality in patients with chronic hepatitis C
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    Alimentary Pharmacology & Therapeutics.2023; 57(2): 272.     CrossRef
  • The association of fatty liver and risk of hepatocellular carcinoma in HBV or HCV infected individuals: a systematic review and meta-analysis
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    Expert Review of Gastroenterology & Hepatology.2023; 17(2): 189.     CrossRef
  • Hepatitis B virus infection combined with nonalcoholic fatty liver disease: Interaction and prognosis
    Lili Liu, Hong Li, Yang Zhang, Jing Zhang, Zhenhuan Cao
    Heliyon.2023; 9(1): e13113.     CrossRef
  • Liver fibrosis is closely related to metabolic factors in metabolic associated fatty liver disease with hepatitis B virus infection
    Haifeng Lv, Yanming Jiang, Geli Zhu, Shiyi Liu, Dian Wang, Jie Wang, Ke Zhao, Jing Liu
    Scientific Reports.2023;[Epub]     CrossRef
  • Positive hepatitis B core antibody is associated with advanced fibrosis and mortality in nonalcoholic fatty liver disease
    Pengyan Zhang, Zhenqiu Liu, Hong Fan, Tingting Shi, Xinyu Han, Chen Suo, Xingdong Chen, Tiejun Zhang
    European Journal of Gastroenterology & Hepatology.2023; 35(3): 294.     CrossRef
  • A novel non‐invasive model for the prediction of advanced liver fibrosis in chronic hepatitis B patients with NAFLD
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    Journal of Viral Hepatitis.2023; 30(4): 287.     CrossRef
  • Baseline hepatocyte ballooning is a risk factor for adverse events in patients with chronic hepatitis B complicated with nonalcoholic fatty liver disease
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    World Journal of Hepatology.2023; 15(2): 237.     CrossRef
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    Medicine.2023; 102(9): e33062.     CrossRef
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  • The hepatitis B virus promotes the progression of non-alcoholic fatty liver disease through incomplete autophagy
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    Free Radical Biology and Medicine.2023; 204: 326.     CrossRef
  • Impact of prior HBV, HAV, and HEV infection on non‐alcoholic fatty liver disease
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    Journal of Viral Hepatitis.2023; 30(8): 685.     CrossRef
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    JHEP Reports.2023; 5(9): 100810.     CrossRef
  • Impact of fatty liver on long-term outcomes in chronic hepatitis B: a systematic review and matched analysis of individual patient data meta-analysis
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  • Clinical study of ganshuang granule combined with tenofovir in the treatment of chronic hepatitis B complicated with nonalcoholic fatty liver disease
    Changtian Su, Qin Yang
    Frontiers in Pharmacology.2022;[Epub]     CrossRef
  • NAFLD and HBV interplay - related mechanisms underlying liver disease progression
    Evanthia Tourkochristou, Stelios F. Assimakopoulos, Konstantinos Thomopoulos, Markos Marangos, Christos Triantos
    Frontiers in Immunology.2022;[Epub]     CrossRef
  • Metabolic syndromes, hepatitis B virus (HBV), and hepatitis C virus as three factors involved in the development of hepatic steatosis: a systematic review and meta-analysis
    Masoud Keikha, Amirhossein Sahebkar, Tannaz Jamialahmadi, Mohsen Karbalaei
    Reviews and Research in Medical Microbiology.2022; 33(3): 139.     CrossRef
  • Secondary prevention of hepatitis B virus‐related hepatocellular carcinoma with current antiviral therapies
    Jonggi Choi, Young‐Suk Lim
    The Kaohsiung Journal of Medical Sciences.2021; 37(4): 262.     CrossRef
  • HRD1 attenuates the high uptake of [18F]FDG in hepatocellular carcinoma PET imaging
    Ai-Mei Li, Xia-Wen Lin, Jing-Tao Shen, Min Li, Qi-Huang Zheng, Zheng-Yang Zhou, Ming Shi
    Nuclear Medicine and Biology.2021; 96-97: 27.     CrossRef
  • The FIB-4 Index Is a Useful Predictor for the Development of Hepatocellular Carcinoma in Patients with Coexisting Nonalcoholic Fatty Liver Disease and Chronic Hepatitis B
    Minah Kim, Yeonju Lee, Jun Sik Yoon, Minjong Lee, So Shin Kye, Sun Woong Kim, Yuri Cho
    Cancers.2021; 13(10): 2301.     CrossRef
  • Association of Metabolic Risk Factors With Risks of Cancer and All‐Cause Mortality in Patients With Chronic Hepatitis B
    Yun Bin Lee, Hyemi Moon, Jeong‐Hoon Lee, Eun Ju Cho, Su Jong Yu, Yoon Jun Kim, Fabien Zoulim, Juneyoung Lee, Jung‐Hwan Yoon
    Hepatology.2021; 73(6): 2266.     CrossRef
  • Pyroptosis: mechanisms and diseases
    Pian Yu, Xu Zhang, Nian Liu, Ling Tang, Cong Peng, Xiang Chen
    Signal Transduction and Targeted Therapy.2021;[Epub]     CrossRef
  • Metabolic dysfunction-associated fatty liver disease increases risk of adverse outcomes in patients with chronic hepatitis B
    Laurens A. van Kleef, Hannah S.J. Choi, Willem P. Brouwer, Bettina E. Hansen, Keyur Patel, Robert A. de Man, Harry L.A. Janssen, Robert J. de Knegt, Milan J. Sonneveld
    JHEP Reports.2021; 3(5): 100350.     CrossRef
  • Systematic review with meta‐analysis: prevalence of hepatic steatosis, fibrosis and associated factors in chronic hepatitis B
    Qi Zheng, Biyao Zou, Yuankai Wu, Yeehui Yeo, Huizhen Wu, Christopher D Stave, Ramsey C. Cheung, Mindie H. Nguyen
    Alimentary Pharmacology & Therapeutics.2021; 54(9): 1100.     CrossRef
  • Association of central obesity with hepatocellular carcinoma in patients with chronic hepatitis B receiving antiviral therapy
    Rong Fan, Junqi Niu, Hong Ma, Qing Xie, Jun Cheng, Huiying Rao, Xiaoguang Dou, Jianping Xie, Wei Zhao, Jie Peng, Zhiliang Gao, Hongbo Gao, Xinyue Chen, Jinjun Chen, Qiang Li, Hong Tang, Zhengang Zhang, Hong Ren, Mingliang Cheng, Xieer Liang, Chaonan Zhu,
    Alimentary Pharmacology & Therapeutics.2021; 54(3): 329.     CrossRef
  • Controlled attenuation parameter value and the risk of hepatocellular carcinoma in chronic hepatitis B patients under antiviral therapy
    Joo Hyun Oh, Hye Won Lee, Dong Hyun Sinn, Jun Yong Park, Beom Kyung Kim, Seung Up Kim, Do Young Kim, Sang Hoon Ahn, Wonseok Kang, Geum-Youn Gwak, Moon Seok Choi, Joon Hyeok Lee, Kwang Cheol Koh, Seung Woon Paik, Yong-Han Paik
    Hepatology International.2021; 15(4): 892.     CrossRef
  • Chronic hepatitis B infection with concomitant hepatic steatosis: Current evidence and opinion
    Yi-Wen Shi, Rui-Xu Yang, Jian-Gao Fan
    World Journal of Gastroenterology.2021; 27(26): 3971.     CrossRef
  • The Prognostic Role of On-Treatment Liver Stiffness for Hepatocellular Carcinoma Development in Patients with Chronic Hepatitis B
    Hye Won Lee, Hyun Woong Lee, Jae Seung Lee, Yun Ho Roh, Hyein Lee, Seung Up Kim, Jun Yong Park, Do Young Kim, Sang Hoon Ahn, Beom Kyung Kim
    Journal of Hepatocellular Carcinoma.2021; Volume 8: 467.     CrossRef
  • REPLY:
    Yun Bin Lee, Juneyoung Lee
    Hepatology.2021; 74(2): 1135.     CrossRef
  • Reply
    Hye Won Lee, Beom Kyung Kim
    Clinical Gastroenterology and Hepatology.2020; 18(1): 264.     CrossRef
  • Magnetic resonance imaging of obesity and metabolic disorders: Summary from the 2019 ISMRM Workshop
    Houchun H. Hu, Rosa Tamara Branca, Diego Hernando, Dimitrios C. Karampinos, Jürgen Machann, Charles A. McKenzie, Holden H. Wu, Takeshi Yokoo, S. Sendhil Velan
    Magnetic Resonance in Medicine.2020; 83(5): 1565.     CrossRef
  • Abnormal CD44 activation of hepatocytes with nonalcoholic fatty accumulation in rat hepatocarcinogenesis
    Miao Fang, Min Yao, Jie Yang, Wen-Jie Zheng, Li Wang, Deng-Fu Yao
    World Journal of Gastrointestinal Oncology.2020; 12(1): 66.     CrossRef
  • Chronic hepatitis B and non‐alcoholic fatty liver disease: Conspirators or competitors?
    Jianbin Zhang, Shuangzhe Lin, Daixi Jiang, Mengting Li, Yuanwen Chen, Jun Li, Jiangao Fan
    Liver International.2020; 40(3): 496.     CrossRef
  • Earlier Alanine Aminotransferase Normalization During Antiviral Treatment Is Independently Associated With Lower Risk of Hepatocellular Carcinoma in Chronic Hepatitis B
    Jonggi Choi, Gi-Ae Kim, Seungbong Han, Young-Suk Lim
    American Journal of Gastroenterology.2020; 115(3): 406.     CrossRef
  • Approach to the patient with chronic hepatitis B and decompensated cirrhosis
    Mitchell L. Shiffman
    Liver International.2020; 40(S1): 22.     CrossRef
  • Presence of Hepatic Steatosis Does Not Increase the Risk of Hepatocellular Carcinoma in Patients With Chronic Hepatitis B Over Long Follow-Up
    Chong Teik Lim, George Boon Bee Goh, Huihua Li, Tony Kiat-Hon Lim, Wei Qiang Leow, Wei Keat Wan, Rafay Azhar, Wan Cheng Chow, Rajneesh Kumar
    Microbiology Insights.2020;[Epub]     CrossRef
  • Risk of Hepatocellular Carcinoma With Tenofovir vs Entecavir in Patients With Chronic Hepatitis B
    Han Ah Lee, Yeon Seok Seo, Seung Up Kim
    Gastroenterology.2020; 158(8): 2310.     CrossRef
  • Radiologic Nonalcoholic Fatty Liver Disease Increases the Risk of Hepatocellular Carcinoma in Patients With Suppressed Chronic Hepatitis B
    Hyeki Cho, Young Chang, Jeong-Hoon Lee, Young Youn Cho, Joon Yeul Nam, Yun Bin Lee, Dong Ho Lee, Eun Ju Cho, Su Jong Yu, Yoon Jun Kim, Jeong Min Lee, Jung-Hwan Yoon
    Journal of Clinical Gastroenterology.2020; 54(7): 633.     CrossRef
  • A New Endemic of Concomitant Nonalcoholic Fatty Liver Disease and Chronic Hepatitis B
    Hira Hanif, Muzammil M. Khan, Mukarram J. Ali, Pir A. Shah, Jinendra Satiya, Daryl T.Y. Lau, Aysha Aslam
    Microorganisms.2020; 8(10): 1526.     CrossRef
  • Letter: fatty liver disease could have been a confounding factor for phase change in patients with chronic hepatitis B in the immune‐tolerant phase—authors' reply
    Han Ah Lee, Seung Up Kim
    Alimentary Pharmacology & Therapeutics.2020; 52(6): 1094.     CrossRef
  • The Effects of Hepatic Steatosis on the Natural History of HBV Infection
    Idrees Suliman, Noha Abdelgelil, Farah Kassamali, Tarek I. Hassanein
    Clinics in Liver Disease.2019; 23(3): 433.     CrossRef
  • 14,318 View
  • 384 Download
  • 95 Web of Science
  • Crossref

Steatotic liver disease

Effect of vitamin E in nonalcoholic fatty liver disease with metabolic syndrome: A propensity score-matched cohort study
Gi Hyun Kim, Jung Wha Chung, Jong Ho Lee, Kyeong Sam Ok, Eun Sun Jang, Jaihwan Kim, Cheol Min Shin, Young Soo Park, Jin-Hyeok Hwang, Sook-Hyang Jeong, Nayoung Kim, Dong Ho Lee, Jin-Wook Kim
Clin Mol Hepatol 2015;21(4):379-386.
Published online December 24, 2015
DOI: https://doi.org/10.3350/cmh.2015.21.4.379
Background/Aims

Vitamin E improves the biochemical profiles and liver histology in nonalcoholic steatohepatitis, but the role of vitamin E is not clearly defined in the management of nonalcoholic fatty liver disease (NAFLD) which includes both simple steatosis and steatohepatitis. Co-morbid metabolic syndrome increases the probability of steatohepatitis in NAFLD. In this study, we aimed to determine the short-term effects of vitamin E and off-treatment durability of response in a propensity-score matched cohort of NAFLD patients with metabolic syndrome.

Methods

A retrospective cohort was constructed by retrieving 526 consecutive NAFLD patients from the electronic medical record data warehouse of a tertiary referral hospital in South Korea. Among them, 335 patients (63.7%) had metabolic syndrome and were eligible for vitamin E therapy. In order to assess the effect of vitamin E, propensity score matching was used by matching covariates between control patients (n=250) and patients who received vitamin E (n=85).

Results

The PS-matched vitamin E group (n=58) and control group (n=58) exhibited similar baseline metabolic profiles. After 6 months of vitamin E therapy, the mean ALT levels decreased significantly compared to PS-matched control (P<0.01). The changes in metabolic profiles (body weight, lipid and glucose levels) did not differ between control and vitamin E groups during the study period.

Conclusions

Short-term vitamin E treatment significantly reduces ALT levels in NAFLD patients with metabolic syndrome, but metabolic profiles are not affected by vitamin E.

Citations

Citations to this article as recorded by  Crossref logo
  • Pathological features of non-alcoholic steatohepatitis in a pediatric patient with heterozygous familial hypobetalipoproteinemia: A case report
    Kiwako Miyamoto, Sonoko Kondo, Takeo Kondo, Ryou Ishikawa, Ryosuke Tani, Tomoko Inoue, Keiji Matsunaga, Tetsuo Minamino, Takashi Kusaka
    World Journal of Hepatology.2025;[Epub]     CrossRef
  • Modulatory impact of wheat metabolome on Wnt/β-catenin signaling pathway in an obesity-induced rat model
    Noha El-Zeiny, Rasha Hanafi, Heba Handoussa
    Food Bioscience.2025; 68: 106508.     CrossRef
  • Vitamin E and Non-alcoholic Fatty Liver Disease: Investigating the Evidence Through a Systematic Review
    Mahlet Abera, Suchith B Suresh, Aparna Malireddi, Sruthi Boddeti, Khutaija Noor, Mehwish Ansar, Iana Malasevskaia
    Cureus.2024;[Epub]     CrossRef
  • Allium sativum: A potential natural compound for NAFLD prevention and treatment
    Parham Mardi, Reza Kargar, Ramina Fazeli, Mostafa Qorbani
    Frontiers in Nutrition.2023;[Epub]     CrossRef
  • Exploring the Impact of Nutrition on Non-Alcoholic Fatty Liver Disease Management: Unveiling the Roles of Various Foods, Food Components, and Compounds
    Marcin Kosmalski, Rafał Frankowski, Kacper Deska, Monika Różycka-Kosmalska, Tadeusz Pietras
    Nutrients.2023; 15(13): 2838.     CrossRef
  • Effect of Vitamin E on Clinical Outcomes in Patients With Non-alcoholic Fatty Liver Disease: A Meta-Analysis
    Jithin Karedath, Hiba Javed, Fatima Ahsan Talpur, Bihari Lal, Anmol Kumari, Husam Kivan, Venkata Anirudh Chunchu, Shamsha Hirani
    Cureus.2022;[Epub]     CrossRef
  • Current innovations in nutraceuticals and functional foods for intervention of non-alcoholic fatty liver disease
    Mengyao Zhao, Shumin Chen, Xiaoguo Ji, Xin Shen, Jiangshan You, Xinyi Liang, Hao Yin, Liming Zhao
    Pharmacological Research.2021; 166: 105517.     CrossRef
  • Can vitamin E supplementation affect obesity indices? A systematic review and meta-analysis of twenty-four randomized controlled trials
    Mohammad Reza Emami, Sanaz Jamshidi, Meysam Zarezadeh, Masoud Khorshidi, Beheshteh Olang, Zohreh Sajadi Hezaveh, Mohammadhassan Sohouli, Naheed Aryaeian
    Clinical Nutrition.2021; 40(5): 3201.     CrossRef
  • Use of a bioengineered antioxidant in mouse models of metabolic syndrome
    Deric M. Griffin, Brittany R. Bitner, Zachary Criss Ii, Daniela Marcano, Jacob M. Berlin, Thomas A. Kent, James M. Tour, Susan L. Samson, Robia G. Pautler
    Expert Opinion on Investigational Drugs.2020; 29(2): 209.     CrossRef
  • VII. The Evidence of Pharmacologic Treatment for NASH
    Masashi Yoneda
    Nihon Naika Gakkai Zasshi.2020; 109(1): 56.     CrossRef
  • Gamma-tocopherol ameliorates hyperglycemia-induced hepatic inflammation associated with NLRP3 inflammasome in alloxan-induced diabetic mice
    Heaji Lee, Yunsook Lim
    Nutrition Research and Practice.2019; 13(5): 377.     CrossRef
  • Effect of vitamin E in non-alcoholic fatty liver disease: a systematic review and meta-analysis of randomised controlled trials
    Iram Amanullah, Yusra Habib Khan, Iqraa Anwar, Aqsa Gulzar, Tauqeer Hussain Mallhi, Ahsan Aftab Raja
    Postgraduate Medical Journal.2019; 95(1129): 601.     CrossRef
  • Haptoglobin Genotype and Vitamin E Versus Placebo for the Treatment of Nondiabetic Patients with Nonalcoholic Steatohepatitis in China: A Multicenter, Randomized, Placebo-Controlled Trial Design
    Shufei Zang, Jin Chen, Yu Song, Lang Bai, Jinjun Chen, Xiaoling Chi, Fangping He, Huiping Sheng, Jing Wang, Shilong Xie, Wen Xie, Yongfeng Yang, Jing Zhang, Minghua Zheng, Zhengsheng Zou, Bingyuan Wang, Junping Shi
    Advances in Therapy.2018; 35(2): 218.     CrossRef
  • An Overview of Novel Dietary Supplements and Food Ingredients in Patients with Metabolic Syndrome and Non-Alcoholic Fatty Liver Disease
    Priscila Silva Figueiredo, Aline Inada, Melina Ribeiro Fernandes, Daniela Granja Arakaki, Karine Freitas, Rita Avellaneda Guimarães, Valter Aragão do Nascimento, Priscila Aiko Hiane
    Molecules.2018; 23(4): 877.     CrossRef
  • 17,355 View
  • 190 Download
  • 17 Web of Science
  • Crossref

Editorial

Liver function tests as indicators of metabolic syndrome
Han Chu Lee
Korean J Hepatol 2011;17(1):9-11.
Published online March 21, 2011
DOI: https://doi.org/10.3350/kjhep.2011.17.1.9

Citations

Citations to this article as recorded by  Crossref logo
  • Is Gender an Important Factor in the Precision Medicine Approach to Levocetirizine?
    Seung-Hyun Jeong, Ji-Hun Jang, Yong-Bok Lee
    Pharmaceutics.2024; 16(1): 146.     CrossRef
  • Increased BMI ‘alone’ does not negatively influence sperm function - a retrospective analysis of men attending fertility treatment with corresponding liver function results
    Nicole O. McPherson, Kelton Tremellen
    Obesity Research & Clinical Practice.2020; 14(2): 164.     CrossRef
  • Association between chronic hepatitis B infection and metabolic syndrome
    Xiaohui Zhao, Drishti Shah, Usha Sambamoorthi
    Journal of Diabetes & Metabolic Disorders.2018; 17(2): 223.     CrossRef
  • Association between liver function and metabolic syndrome in Chinese men and women
    Sen Wang, Jie Zhang, Li Zhu, Linlin Song, Zhaowei Meng, Qiang Jia, Xue Li, Na Liu, Tianpeng Hu, Pingping Zhou, Qing Zhang, Li Liu, Kun Song, Qiyu Jia
    Scientific Reports.2017;[Epub]     CrossRef
  • 8,973 View
  • 51 Download
  • Crossref

Original Articles

Association of serum alanine aminotransferase and γ-glutamyltransferase levels within the reference range with metabolic syndrome and nonalcoholic fatty liver disease
Hyo Jeong Oh, Tae Hyeon Kim, Young Woo Sohn, Yong Sung Kim, Yong Reol Oh, Eun Young Cho, So Yeon Shim, Sae Ron Shin, A Lum Han, Seok Jin Yoon, Haak Cheoul Kim
Korean J Hepatol 2011;17(1):27-36.
Published online March 21, 2011
DOI: https://doi.org/10.3350/kjhep.2011.17.1.27
Background/Aims

Nonalcoholic fatty liver disease (NAFLD) has recently been found to be a novel component of metabolic syndrome (MS), which is one of the leading causes of chronic liver disease. The serum alanine aminotransferase (ALT) and γ-glutamyltransferase (GGT) levels are suggested to affect liver fat accumulation and insulin resistance. We assessed the associations of serum ALT and GGT concentrations within the reference ranges with MS and NAFLD.

Methods

In total, 1,069 subjects enrolled at the health promotion center of Wonkwang University Hospital were divided into 4 groups according to serum ALT and GGT concentrations levels within the reference ranges. We performed biochemical tests, including liver function tests and lipid profiles, and diagnosed fatty liver by ultrasonography. Associations of ALT and GGT concentrationgrading within the reference range with fatty liver and/or MS were investigated.

Results

The presence of MS, its components, and the number of metabolic abnormalities [except for high-density lipoprotein-cholesterol (HDL-C) and fasting blood glucose] increased with the ALT level, while the presence of MS, its components, and the number of metabolic abnormalities (except for HDL-C) increased with the GGT level. The odds ratios for fatty liver and MS increased with the ALT level (P<0.001 and P=0.049, respectively) and the GGT level (P=0.044 and P=0.039, respectively).

Conclusions

Serum ALT and GGT concentrations within the reference ranges correlated with the incidence of NAFLD and MS in a dose-dependent manner. There associations need to be confirmed in large, prospective studies.

Citations

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  • Elucidating the biological characteristics of overweight populations based on urine Raman spectroscopy and bioinformatics analysis
    Ying Li, Yuyang Miao, Haoyue Liang, Kexuan Zhou, Ruihua Li, Jinfeng Qi, Xiaodong Kong, Yuan Zhou, Qiang Zhang
    Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy.2026; 350: 127442.     CrossRef
  • Therapeutic effects of curcumin supplementation on liver enzymes of nonalcoholic fatty liver disease patients: A systematic review and meta‐analysis of randomized clinical trials
    Armin Ebrahimzadeh, Anahita Ebrahimzadeh, Sara Fooladshekan, Shokouh Mohseni, Abbas Mohtashamian, Siavash Babajafari, Zahra Sohrabi
    Food Science & Nutrition.2025;[Epub]     CrossRef
  • Elevated serum neprilysin levels in patients with chronic hepatitis C and metabolic dysfunction-associated steatotic liver disease: hepatic oxidative stress as an underlying mechanism
    Kensuke Kitsugi, Takeshi Chida, Tomohiko Hanaoka, Masahiro Umemura, Maho Yamashita, Jun Ito, Kazuyoshi Ohta, Hidenao Noritake, Takafumi Suda, Kazuhito Kawata
    Molecular Biology Reports.2025;[Epub]     CrossRef
  • Prevalence and Risk Factors of Non-Alcoholic Fatty Liver Disease (NAFLD) in Non-Obese Patients with Schizophrenia: A Retrospective Study
    Wenying Yi, Haibo Wu, Weibin Fu, Huimei Feng, Jie Huang, Haijing Li, Zhen Song, Yuwei Chen, Yingjun Zheng, Shenglin She
    Diabetes, Metabolic Syndrome and Obesity.2024; Volume 17: 841.     CrossRef
  • Elevated ALT/AST ratio as a marker for NAFLD risk and severity: insights from a cross-sectional analysis in the United States
    Yanyan Xuan, Dingting Wu, Qin Zhang, Zhiqiang Yu, Jingbo Yu, Dongdong Zhou
    Frontiers in Endocrinology.2024;[Epub]     CrossRef
  • Development and validation of an online dynamic nomogram based on the atherogenic index of plasma to screen nonalcoholic fatty liver disease
    Hewei Peng, Junchao Zhang, Xianhua Huang, Miao Xu, Jingru Huang, Yunli Wu, Xian-E. Peng
    Lipids in Health and Disease.2023;[Epub]     CrossRef
  • The newly proposed alanine aminotransferase to high-density lipoprotein cholesterol ratio has shown effectiveness in identifying non-alcoholic fatty liver disease
    Jiajun Qiu, Maobin Kuang, Ruijuan Yang, Changhui Yu, Shiming He, Guotai Sheng, Yang Zou
    Frontiers in Endocrinology.2023;[Epub]     CrossRef
  • Identifying inflammatory bowel disease patients at risk of metabolic dysfunction-associated fatty liver disease: usefulness of non-invasive steatosis predictive scores
    Tiago Lima Capela, Vítor Macedo Silva, Marta Freitas, Cátia Arieira, Tiago Cúrdia Gonçalves, Francisca Dias de Castro, Joana Magalhães, José Cotter
    BMC Gastroenterology.2023;[Epub]     CrossRef
  • 2019 Global NAFLD Prevalence: A Systematic Review and Meta-analysis
    Michael H. Le, Yee Hui Yeo, Xiaohe Li, Jie Li, Biyao Zou, Yuankai Wu, Qing Ye, Daniel Q. Huang, Changqing Zhao, Jie Zhang, Chenxi Liu, Na Chang, Feng Xing, Shiping Yan, Zi Hui Wan, Natasha Sook Yee Tang, Maeda Mayumi, Xinting Liu, Chuanli Liu, Fajuan Rui,
    Clinical Gastroenterology and Hepatology.2022; 20(12): 2809.     CrossRef
  • Residual liver stiffness in the postpartum period in women with preeclampsia and healthy women: A case-control study
    José Rojas-Suárez, Sandra Contreras-Arrieta, Jose Santacruz, Jharitza Julio, Maria Cueter, Douglas Carrasquilla, Walter Anichiarico, Ismael Yepes
    Pregnancy Hypertension.2022; 28: 156.     CrossRef
  • Effect of Probiotics on Liver Enzymes in Patients With Non-alcoholic Fatty Liver Disease: An Umbrella of Systematic Review and Meta-Analysis
    Vali Musazadeh, Neda Roshanravan, Parvin Dehghan, Sana Sedgh Ahrabi
    Frontiers in Nutrition.2022;[Epub]     CrossRef
  • Association between serum apolipoprotein B and atrial fibrillation: a case–control study
    Xia Zhong, Huachen Jiao, Dongsheng Zhao, Jing Teng
    Scientific Reports.2022;[Epub]     CrossRef
  • Can Gamma-glutamyl Transferase Predict Unhealthy Metabolic Phenotypes Among Healthcare Workers in Azar Cohort Study?
    Mohammadhossein Somi, Seyed Sina Zakavi, Alireza Ostadrahimi, Negin Frounchi, Neda Gilani, Sarvin Sanaie, Elnaz Faramarzi
    Hepatitis Monthly.2022;[Epub]     CrossRef
  • Low aspartate aminotransferase/alanine aminotransferase (DeRitis) ratio assists in predicting diabetes in Chinese population
    Wangcheng Xie, Weidi Yu, Shanshan Chen, Zhilong Ma, Tingsong Yang, Zhenshun Song
    Frontiers in Public Health.2022;[Epub]     CrossRef
  • La utilidad clínica de la elastografía transitoria como una herramienta de imagenología para evaluar el impacto a corto plazo de la gastrectomía laparoscópica en manga, en conjunto con parámetros clínicos y bioquímicos e índices clínico-bioquímicos en pac
    M.S. Abdelbary, R. Marzaban, H. Gamal Eldeen, M. Khairy, M. Menesy, M.H. Fahmy, A.M. Ayad, B.S. Mouheb, A. Yosry
    Revista de Gastroenterología de México.2021; 86(2): 125.     CrossRef
  • Exploring the Changes of Peroxisomal Polarity in the Liver of Mice with Nonalcoholic Fatty Liver Disease
    Yongqing Zhou, Chuanchen Wu, Xin Wang, Ping Li, Nannan Fan, Wei Zhang, Zhenzhen Liu, Wen Zhang, Bo Tang
    Analytical Chemistry.2021; 93(27): 9609.     CrossRef
  • Effect of fermented Rhus verniciflua stokes extract on liver function parameters in healthy Korean adults: a double-blind randomized controlled trial
    Jung Hyun Kwak, Hyo-Jeong Lee, Seok-Tae Jeong, Ju Yeon Lee, Minho Lee, Jean Kyung Paik
    Trials.2021;[Epub]     CrossRef
  • Clinical utility of transient elastography as an imaging tool to assess the short-term impact of laparoscopic sleeve gastrectomy, together with clinical and biochemical parameters and clinico-biochemical indices, on obese patients with nonalcoholic fatty
    M.S. Abdelbary, R. Marzaban, H. Gamal Eldeen, M. Khairy, M. Menesy, M.H. Fahmy, A.M. Ayad, B.S. Mouheb, A. Yosry
    Revista de Gastroenterología de México (English Edition).2021; 86(2): 125.     CrossRef
  • Comparison of clinical features and outcomes between HBV-related and non-B non-C hepatocellular carcinoma
    Xiulan Xue, Wei Liao, Yugang Xing
    Infectious Agents and Cancer.2020;[Epub]     CrossRef
  • Insulin resistance is related with liver fibrosis in type 2 diabetic patients with non-alcoholic fatty liver disease proven biopsy and Mediterranean diet pattern as a protective factor
    Rocío Aller, Rebeca Sigüenza, María Pina, Cristina Laserna, Beatriz Antolín, Beatriz Burgueño, Miguel Durà, Olatz Izaola, David Primo, Daniel Antonio de Luis
    Endocrine.2020; 68(3): 557.     CrossRef
  • The Association Between Liver Function Tests and Some Metabolic Outcomes: Tehran Lipid and Glucose Study
    Zahra Gaeini, Zahra Bahadoran, Parvin Mirmiran, Fereidoun Azizi
    Hepatitis Monthly.2020;[Epub]     CrossRef
  • Mercury Exposure and Associations with Hyperlipidemia and Elevated Liver Enzymes: A Nationwide Cross-Sectional Survey
    Seungho Lee, Sung-Ran Cho, Inchul Jeong, Jae Bum Park, Mi-Yeon Shin, Sungkyoon Kim, Jin Hee Kim
    Toxics.2020; 8(3): 47.     CrossRef
  • Association between the alanine aminotransferase/aspartate aminotransferase ratio and new-onset non-alcoholic fatty liver disease in a nonobese Chinese population: a population-based longitudinal study
    Yang Zou, Ling Zhong, Chong Hu, Guotai Sheng
    Lipids in Health and Disease.2020;[Epub]     CrossRef
  • The longitudinal increments of serum alanine aminotransferase increased the incidence risk of metabolic syndrome: A large cohort population in China
    Hongge Sun, Qigui Liu, Xiaorong Wang, Meng Li, Yongjun Fan, Guirong Song, Ying Liu
    Clinica Chimica Acta.2019; 488: 242.     CrossRef
  • Potential impact of the joint association of total bilirubin and gamma-glutamyltransferase with metabolic syndrome
    Makoto Shiraishi, Muhei Tanaka, Hiroshi Okada, Yoshitaka Hashimoto, Shinichi Nakagawa, Muneaki Kumagai, Teruyuki Yamamoto, Hiromi Nishimura, Yohei Oda, Michiaki Fukui
    Diabetology & Metabolic Syndrome.2019;[Epub]     CrossRef
  • Elevated serum levels of aminotransferases in relation to unhealthy foods intake: Tehran lipid and glucose study
    Parvin Mirmiran, Zahra Gaeini, Zahra Bahadoran, Fereidoun Azizi
    BMC Endocrine Disorders.2019;[Epub]     CrossRef
  • Prevalence and clinical characteristics of non-alcoholic fatty liver disease in newly diagnosed patients with ketosis-onset diabetes
    T.-T. Li, A.-P. Wang, J.-X. Lu, M.-Y. Chen, C.-C. Zhao, Z.-H. Tang, L.-X. Li, W.-P. Jia
    Diabetes & Metabolism.2018; 44(5): 437.     CrossRef
  • Prepartal standing behavior as a parameter for early detection of postpartal subclinical ketosis associated with inflammation and liver function biomarkers in peripartal dairy cows
    S. Rodriguez-Jimenez, K.J. Haerr, E. Trevisi, J.J. Loor, F.C. Cardoso, J.S. Osorio
    Journal of Dairy Science.2018; 101(9): 8224.     CrossRef
  • Risk factors associated with nonalcohol fatty liver disease and fibrosis among patients with type 2 diabetes mellitus
    Hongli Zhao, Xiangxin Song, Zhang Li, Xinling Wang
    Medicine.2018; 97(37): e12356.     CrossRef
  • Correlation between normal range of serum alanine aminotransferase level and metabolic syndrome
    Han Shen, Jing Lu, Ting-Ting Shi, Cheng Cheng, Jing-Yi Liu, Jian-Ping Feng, Jin-Kui Yang
    Medicine.2018; 97(41): e12767.     CrossRef
  • Study of serum visfatin level in patients with nonalcoholic fatty liver disease and its role in progression to nonalcoholic steatohepatitis
    George S. Riad, Hany A. Hussein, Ahmed Z. Abdel Ghafar
    Egyptian Liver Journal.2018; 8(2): 49.     CrossRef
  • Periodontal Status of Patients with Hepatitis B Viruses and B and C Virus (Comparative Study)
    Ali Al-Sharqi
    Journal of Pure and Applied Microbiology.2018; 12(1): 293.     CrossRef
  • Supplementing Zn, Mn, and Cu from amino acid complexes and Co from cobalt glucoheptonate during the peripartal period benefits postpartal cow performance and blood neutrophil function
    J.S. Osorio, E. Trevisi, C. Li, J.K. Drackley, M.T. Socha, J.J. Loor
    Journal of Dairy Science.2016; 99(3): 1868.     CrossRef
  • Metabolic Syndrome and Serum Liver Enzymes in the General Chinese Population
    Shuang Chen, Xiaofan Guo, Shasha Yu, Ying Zhou, Zhao Li, Yingxian Sun
    International Journal of Environmental Research and Public Health.2016; 13(2): 223.     CrossRef
  • Development and Validation of the Framingham Steatosis Index to Identify Persons With Hepatic Steatosis
    Michelle T. Long, Alison Pedley, Lisandro D. Colantonio, Joseph M. Massaro, Udo Hoffmann, Paul Muntner, Caroline S. Fox
    Clinical Gastroenterology and Hepatology.2016; 14(8): 1172.     CrossRef
  • Interaction between periodontitis and liver diseases
    Pengyu Han, Dianxing Sun, Jie Yang
    Biomedical Reports.2016; 5(3): 267.     CrossRef
  • Subclinical and clinical hypothyroidism and non-alcoholic fatty liver disease: a cross-sectional study of a random population sample aged 18 to 65 years
    Ulla Ludwig, Daniela Holzner, Christian Denzer, Artur Greinert, Mark Martin Haenle, Suemeyra Oeztuerk, Wolfgang Koenig, Bernhard Otto Boehm, Richard Andrew Mason, Wolfgang Kratzer, Tilmann Graeter
    BMC Endocrine Disorders.2015;[Epub]     CrossRef
  • Citrus limonin glucoside supplementation decreased biomarkers of liver disease and inflammation in overweight human adults
    Darshan S. Kelley, Yuriko C. Adkins, Susan J. Zunino, Leslie R. Woodhouse, Ellen L. Bonnel, Andrew P. Breksa, Gary D. Manners, Bruce E. Mackey
    Journal of Functional Foods.2015; 12: 271.     CrossRef
  • Impact of elevated aspartate and alanine aminotransferase on metabolic syndrome and its components among adult people living in Ningxia, China
    Kun‐Peng He, Chuan Zhao, Yan Qiang, He‐Rong Liu, Nan Chen, Xiu‐Juan Tao, Li‐Li Chen, Hui Song
    Chronic Diseases and Translational Medicine.2015; 1(2): 124.     CrossRef
  • Serum Gamma-glutamyl Transferase Concentration Within the Reference Range is Related to the Coronary Heart Disease Risk Prediction in Korean Men
    Kyung-Sun Han, Doo-Yeoun Cho, Young-Sang Kim, Kyu-Nam Kim
    Chinese Medical Journal.2015; 128(15): 2006.     CrossRef
  • Serum γ-Glutamyltransferase Level is Associated with Periodontal Disease Independent of Drinking Habits in Japanese Adults
    Masao Maeno
    Medical Science Monitor.2014; 20: 2109.     CrossRef
  • The Wide and Complex Field of NAFLD Biomarker Research: Trends
    Erika Wichro, Tanja Macheiner, Jasmin Schmid, Barbara Kavsek, Karine Sargsyan
    ISRN Hepatology.2014; 2014: 1.     CrossRef
  • A randomized, double-blind placebo-controlled study on acceptability, safety and efficacy of oral administration of sacha inchi oil (Plukenetia volubilis L.) in adult human subjects
    Gustavo F. Gonzales, Carla Gonzales
    Food and Chemical Toxicology.2014; 65: 168.     CrossRef
  • Alanine Aminotransferase within Reference Range Is Associated with Metabolic Syndrome in Middle-Aged and Elderly Chinese Men and Women
    Xuebing Zhang, Yiming Mu, Wenhua Yan, Jianming Ba, Hongmei Li
    International Journal of Environmental Research and Public Health.2014; 11(12): 12767.     CrossRef
  • Alanine aminotransferase and metabolic syndrome in adolescents: the Korean National Health and Nutrition Examination Survey Study
    J‐H. Park, S‐H. Kim, S. Park, M. J. Park
    Pediatric Obesity.2014; 9(6): 411.     CrossRef
  • Effects of sulfate chitosan derivatives on nonalcoholic fatty liver disease
    Mingming Yu, Yuanhong Wang, Tingfu Jiang, Zhihua Lv
    Journal of Ocean University of China.2014; 13(3): 531.     CrossRef
  • Fatty liver and serum cholinesterase are independently correlated with HbA1c levels: Cross-sectional analysis of 5384 people
    Shuichi Katoh, Markku Peltonen, Takashi Wada, Mikio Zeniya, Yoichi Sakamoto, Kazunori Utsunomiya, Jaakko Tuomilehto
    Journal of International Medical Research.2014; 42(2): 542.     CrossRef
  • Metabolic syndrome in psychiatry: advances in understanding and management
    Cyrus S. H. Ho, Melvyn W. B. Zhang, Anselm Mak, Roger C. M. Ho
    Advances in Psychiatric Treatment.2014; 20(2): 101.     CrossRef
  • Association between γ-Glutamyl Transferase and Metabolic Syndrome: A Cross-Sectional Study of an Adult Population in Beijing
    Lixin Tao, Xia Li, Huiping Zhu, Yue Gao, Yanxia Luo, Wei Wang, Zhaoping Wang, Dongning Chen, Lijuan Wu, Xiuhua Guo
    International Journal of Environmental Research and Public Health.2013; 10(11): 5523.     CrossRef
  • Relation of Circulating Liver Transaminase Concentrations to Risk of New-Onset Atrial Fibrillation
    Moritz F. Sinner, Na Wang, Caroline S. Fox, João D. Fontes, Michiel Rienstra, Jared W. Magnani, Ramachandran S. Vasan, Audrey H. Calderwood, Michael Pencina, Lisa M. Sullivan, Patrick T. Ellinor, Emelia J. Benjamin
    The American Journal of Cardiology.2013; 111(2): 219.     CrossRef
  • Long-term effects of aerobic plus resistance training on the adipokines and neuropeptides in nonalcoholic fatty liver disease obese adolescents
    Aline de Piano, Marco T. de Mello, Priscila de L. Sanches, Patrícia L. da Silva, Raquel M.S. Campos, June Carnier, Flavia Corgosinho, Denis Foschini, Deborah L. Masquio, Lian Tock, Lila M. Oyama, Claudia Maria da Penha Oller do Nascimento, Sérgio Tufik, A
    European Journal of Gastroenterology & Hepatology.2012; : 1.     CrossRef
  • Serum alanine aminotransferase is correlated with hematocrit in healthy human subjects
    Yun Hu, Soren Snitker, Kathleen A. Ryan, Rongze Yang, Braxton D. Mitchell, Alan R. Shuldiner, Dalong Zhu, Da-Wei Gong
    Scandinavian Journal of Clinical and Laboratory Investigation.2012; 72(3): 258.     CrossRef
  • Long-Term Dietary Potential Renal Acid Load During Adolescence Is Prospectively Associated with Indices of Nonalcoholic Fatty Liver Disease in Young Women3
    Danika Krupp, Simone A. Johner, Hermann Kalhoff, Anette E. Buyken, Thomas Remer
    The Journal of Nutrition.2012; 142(2): 313.     CrossRef
  • Factors Predicting the Effi cacy of Adefovir Dipivoxil on Treatment-Naïve Chronic Hepatitis B Patients at 48 Weeks
    Li-Chun Wang, En-Qiang Chen, Xiao-Feng Zhu, Zhong-Hua Xiong, Li Liu, Lu Xu, Xue-Zhong Lei, Cong Liu, Hong Tang
    Gut and Liver.2011; 5(4): 478.     CrossRef
  • Liver function tests as indicators of metabolic syndrome
    Han Chu Lee
    The Korean Journal of Hepatology.2011; 17(1): 9.     CrossRef
  • 13,638 View
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Nonalcoholic fatty Liver disease as a risk factor of cardiovascular disease; Relation of non-alcoholic fatty Liver disease to carotid atherosclerosis
Su-Yeon Choi, M.D., Donghee Kim, M.D., Jin Hwa Kang, M.D.1, Min Jung Park, M.D., Young Sun Kim, M.D., Seon Hee Lim, M.D., Chung Hyeon Kim, M.D., Hyo-Suk Lee, M.D.2
Korean J Hepatol 2008;14(1):77-88.
Published online March 20, 2008
DOI: https://doi.org/10.3350/kjhep.2008.14.1.77
Background/Aims
Non-alcoholic fatty liver disease (NAFLD) is closely associated with abdominal obesity, dyslipidemia, hypertension, and Type 2 diabetes, which are all features of the metabolic syndrome. The aim of the present study was to elucidate whether NAFLD is associated with carotid atherosclerosis. Methods: The study population comprised 659 subjects without hepatitis B and C infections and who did not consume alcohol. Fatty infiltrations of liver were detected by abdominal ultrasonography, and intima-media thickness (IMT) and plaque prevalence were estimated by carotid ultrasonography. Results: The mean values of systolic and diastolic pressures, body mass index (BMI), aspartate aminotransferase, alanine aminotransferase, gamma- glutamyl transpeptidase, uric acid, total cholesterol, triglycerides, high density lipoprotein (HDL) cholesterol, fasting glucose, fasting insulin, homeostasis model of assessment (HOMA) index, hemoglobin A1c, and plasminogen activator inhibitor-1 differed significantly between patients with NAFLD (n=314) and normal controls (n=345). The carotid IMT was 0.817±0.212 (mean±SD) mm in patients with NAFLD and 0.757±0.198 mm in normal controls (p<0.001). The prevalence of carotid plaques was higher in patients with NAFLD (26.4%) than in normal controls (15.9%) (p<0.001). This association persisted significantly after adjusting for age, sex, BMI, HOMA index and individual factors of metabolic syndrome by multiple logistic regression analysis. Conclusions: Patients with NAFLD are at a high risk of carotid atherosclerosis regardless of metabolic syndrome and classical cardiovascular risk factors. Therefore, the detection of NAFLD should alert to the existence of an increased cardiovascular risk. Moreover, NAFLD might be an independent risk factor for cardiovascular disease. (Korean J Hepatol 2008;14:77-88)

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  • Non-alcoholic fatty liver disease (NAFLD) and its association to cardiovascular disease: A comprehensive meta-analysis
    Irina Lubomirova Mladenova, Eu Fon Tan, Jing Yong Ng, Pankaj Sharma
    JRSM Cardiovascular Disease.2025;[Epub]     CrossRef
  • Associations between MASLD phenotypes and the risk of carotid artery plaque: a cross-sectional study among railway workers
    Jia Pan, Honglian Zeng, Yongyan Song, Xiaoli Zhang, Zihang Wang, Lei Tang, Bo Xie, Rong Peng, Yuanyuan Zhou, Beizhong Liu
    Acta Diabetologica.2025; 62(12): 2085.     CrossRef
  • Development of an Educational Model for a Vascular Insertion Device System
    Chan-Woo Park, Pyong-Kon Cho
    Journal of Radiological Science and Technology.2025; 48(4): 385.     CrossRef
  • Conventional ultrasound for diagnosis of hepatic steatosis is better than believed
    Christoph F. Dietrich, Long Shi, Axel Löwe, Yi Dong, Andrej Potthoff, Zeno Sparchez, Andreas Teufel, Sabine Guth, Jonas Koch, Richard G Barr, Xin-Wu Cui
    Zeitschrift für Gastroenterologie.2022; 60(08): 1235.     CrossRef
  • Relationship between Nonalcoholic Fatty Liver Disease and High Sensitivity C-Reactive Protein in Healthy Adults
    Yunhyoung Choi, Jung-Eun Oh, Jin Lee, Hwang-Sik Shin, Yong-Jin Cho, Sun-Hee Kim, Hyun Joe, Byung-Wook Yoo, Sung-Ho Hong, Choo-Yon Cho, Doo-Yong Son, Kyung-Suk Shin
    Korean Journal of Family Practice.2021; 11(1): 39.     CrossRef
  • A practical means of evaluating the prognosis of acute pancreatitis : measurement of carotid artery intima-media thickness
    K Kurkcu, B Kara, A.S. Koc, S.O. Keskek
    Acta Gastro Enterologica Belgica.2021; 84(3): 437.     CrossRef
  • Association of Cardiovascular Risk Factors and Metabolic Syndrome with non-alcoholic and alcoholic fatty liver disease: a retrospective analysis
    A. L. Han
    BMC Endocrine Disorders.2021;[Epub]     CrossRef
  • Liver transplantation and cardiac illness: Current evidences and future directions
    Ajay Kumar Jha, Suman Lata
    Journal of Hepato-Biliary-Pancreatic Sciences.2020; 27(5): 225.     CrossRef
  • Association between cagA negative Helicobacter pylori status and nonalcoholic fatty liver disease among adults in the United States
    Seung Joo Kang, Hwa Jung Kim, Donghee Kim, Aijaz Ahmed, Silvia C. Sookoian
    PLOS ONE.2018; 13(8): e0202325.     CrossRef
  • Reactive hyperemia index can screen endothelial dysfunction in obese subjects with non-alcoholic fatty liver disease
    Shozo Yano, Hiroshi Tobita, Chikako Watano, Seiji Mishima, Yutaka Ishibashi, Abdullah M. Sheikh, Atsushi Nagai
    Vascular Failure.2018; 2(1): 39.     CrossRef
  • Managing diabetes and liver disease association
    Abd Elkhalek Hamed, Medhat Elsahar, Nadia M. Elwan, Sarah El-Nakeep, Mervat Naguib, Hanan Hamed Soliman, Ashraf Ahmed Aboubakr, Amany AbdelMaqsod, Heba Sedrak, Samir N. Assaad, Reda Elwakil, Gamal Esmat, Samira Salh, Taymour Mostafa, Sherif Mogawer, Sameh
    Arab Journal of Gastroenterology.2018; 19(4): 166.     CrossRef
  • Serum Alanine Aminotransferase Levels within Normal Range Have Different Associations with Augmentation Index and Other Cardiometabolic Risk Factors in Nondrinkers and Drinkers: A Chinese Community-Based Analysis
    Shihui Fu, Chunling Liu, Leiming Luo, Ping Ye
    Gastroenterology Research and Practice.2017; 2017: 1.     CrossRef
  • The relationship of serum alanine aminotransferase normal-range levels to arterial stiffness and metabolic syndrome in non-drinkers and drinkers: a Chinese community-based analysis
    Shihui Fu, Ying Lin, Leiming Luo, Ping Ye
    BMC Gastroenterology.2017;[Epub]     CrossRef
  • Arterial stiffness in metabolic syndrome
    Mona Adel, Ayman ELSheikh, Sameh Sameer, Waiel Haseeb, Eman ELSheikh, Lamia Kheder
    Journal of the Saudi Heart Association.2016; 28(4): 249.     CrossRef
  • Prevalence of nonalcoholic fatty liver disease in outpatients in Rostov-on-Don: Regional results of the DIREG-2 study
    A V Tkachev, G N Tarasova, V S Groshilin, D A Vasilchenkov, T I Ushakova, D V Blinov
    Terapevticheskii arkhiv.2016; 88(8): 59.     CrossRef
  • Long-Term Outcomes of Nonalcoholic Fatty Liver Disease
    Min-Sun Kwak, Donghee Kim
    Current Hepatology Reports.2015; 14(2): 69.     CrossRef
  • Nonalcoholic fatty liver disease and carotid artery atherosclerosis in children and adults
    Shivank A. Madan, Febin John, Nikolaos Pyrsopoulos, Capecomorin S. Pitchumoni
    European Journal of Gastroenterology & Hepatology.2015; 27(11): 1237.     CrossRef
  • Nonalcoholic Fatty Liver Disease as a Risk Factor of Arterial Stiffness Measured by the Cardioankle Vascular Index
    Goh Eun Chung, Su-Yeon Choi, Donghee Kim, Min-Sun Kwak, Hyo Eun Park, Min-Kyung Kim, Jeong Yoon Yim
    Medicine.2015; 94(12): e654.     CrossRef
  • Central obesity and nonalcoholic fatty liver disease risk after adjusting for body mass index
    Qing Pang
    World Journal of Gastroenterology.2015; 21(5): 1650.     CrossRef
  • Relationship of Colorectal Polyps and Fatty Liver Disease Diagnosed by Ultrasonography
    Hye-Nam Lee, Cheong-Hwan Lim, Hong-Ryang Jung
    Journal of Digital Convergence.2014; 12(3): 345.     CrossRef
  • The Intima Media Thickness (IMT) as Measured by Carotid Ultrasonography in Patients with Retinal Vascular Diseases
    Sang Jin Seo, Hyun Duk Jang, Soo Jung Lee, Jung Min Park
    Journal of the Korean Ophthalmological Society.2014; 55(4): 541.     CrossRef
  • Noninvasive markers: a double-edged sword that stratifies nonalcoholic steatohepatitis
    Goh Eun Chung, Donghee Kim
    Clinical and Molecular Hepatology.2013; 19(2): 116.     CrossRef
  • Independent Association between Nonalcoholic Fatty Liver Disease and Cardiovascular Disease: A Systematic Review and Meta-Analysis
    Hongyun Lu, Hong Liu, Fang Hu, Lingling Zou, Shunkui Luo, Liao Sun
    International Journal of Endocrinology.2013; 2013: 1.     CrossRef
  • Improvement of metabolic syndrome by irbesartan via the PPARγ/HGF pathway in apolipoprotein E knockout mice
    AMARNATH CHATTERJEE, HIROSHI KUSUNOKI, YOSHIAKI TANIYAMA, HIROMI RAKUGI, RYUICHI MORISHITA
    Biomedical Reports.2013; 1(1): 65.     CrossRef
  • Non-alcoholic fatty liver disease across the spectrum of hypothyroidism
    Goh Eun Chung, Donghee Kim, Won Kim, Jeong Yoon Yim, Min Jung Park, Yoon Jun Kim, Jung-Hwan Yoon, Hyo-Suk Lee
    Journal of Hepatology.2012; 57(1): 150.     CrossRef
  • Which metabolic syndrome criteria best predict the presence of non-alcoholic fatty liver disease?
    Hyun Il Seo, Yong Kyun Cho, Won Young Lee, Eun Jung Rhee, Ki Chul Sung, Bum Soo Kim, Byung Ho Son, Jun Ho Shin, Kwan Joong Joo, Hyun Pyo Hong, Seoung Wan Chae, Wook Jin
    Diabetes Research and Clinical Practice.2012; 95(1): 19.     CrossRef
  • Relationship between Nonalcoholic Fatty Liver Disease and Carotid Artery Atherosclerosis Beyond Metabolic Disorders in Non-Diabetic Patients
    Ji Hoon Kang, Kyoung Im Cho, Seong Man Kim, Ja Young Lee, Jae Joon Kim, Ja Jun Goo, Kyoung Nyoun Kim, Joon Hyung Jhi, Dong Jun Kim, Hyeon Gook Lee, Tae Ik Kim
    Journal of Cardiovascular Ultrasound.2012; 20(3): 126.     CrossRef
  • Nonalcoholic fatty liver disease is associated with coronary artery calcification
    Donghee Kim, Su-Yeon Choi, Eun Ha Park, Whal Lee, Jin Hwa Kang, Won Kim, Yoon Jun Kim, Jung-Hwan Yoon, Sook Hyang Jeong, Dong Ho Lee, Hyo-suk Lee, Joseph Larson, Terry M. Therneau, Ray W. Kim
    Hepatology.2012; 56(2): 605.     CrossRef
  • Carotid Intima-Media Thickness Is Increased Not Only in Non-Alcoholic Fatty Liver Disease Patients but Also in Alcoholic Fatty Liver Patients
    Jeong Han Kim, Seung Young Kim, Eun Seok Jung, Sung Woo Jung, Ja Seol Koo, Ji Hoon Kim, Jong Eun Yeon, So Young Kwon, Sang Woo Lee, Kwan Soo Byun, Chang Hong Lee
    Digestion.2011; 84(2): 149.     CrossRef
  • Association between nonalcoholic fatty liver disease and carotid intima-media thickness according to the presence of metabolic syndrome
    Hyeon Chang Kim, Dae Jung Kim, Kap Bum Huh
    Atherosclerosis.2009; 204(2): 521.     CrossRef
  • The Relation Between Non-Alcoholic Fatty Liver Disease and the Risk of Coronary Heart Disease in Koreans
    Su-Yeon Choi, Donghee Kim, Hwa Jung Kim, Jin Hwa Kang, Su Jin Chung, Min Jung Park, Young Sun Kim, Chung Hyun Kim, Seung Ho Choi, Won Kim, Yoon Jun Kim, Jung-Hwan Yoon, Hyo-Suk Lee, Sang-Heon Cho, Myung-Whun Sung, Byung-Hee Oh
    The American Journal of Gastroenterology.2009; 104(8): 1953.     CrossRef
  • Carotid lesions in outpatients with nonalcoholic fatty liver disease
    Stefano Ramilli, Stefano Pretolani, Antonio Muscari, Barbara Pacelli, Vincenzo Arienti
    World Journal of Gastroenterology.2009; 15(38): 4770.     CrossRef
  • Nonalcoholic fatty liver disease as a risk factor of cardiovascular disease
    Moon Young Kim, Soon Koo Baik
    The Korean Journal of Hepatology.2008; 14(1): 1.     CrossRef
  • 8,289 View
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Editorial

Nonalcoholic fatty Liver disease as a risk factor of cardiovascular disease
Moon Young Kim , Soon Koo Baik
Korean J Hepatol 2008;14(1):1-3.
Published online March 20, 2008
DOI: https://doi.org/10.3350/kjhep.2008.14.1.1

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  • Fibrinogen production is enhanced in an in-vitro model of non-alcoholic fatty liver disease: an isolated risk factor for cardiovascular events?
    Emily N. W. Yeung, Philipp Treskes, Sarah F. Martin, Jonathan R. Manning, Donald R. Dunbar, Sophie M. Rogers, Thierry Le Bihan, K. Ann Lockman, Steven D. Morley, Peter C. Hayes, Leonard J. Nelson, John N. Plevris
    Lipids in Health and Disease.2015;[Epub]     CrossRef
  • Prevalence of Metabolic Syndrome and Related Risk Factors of Elderly Residents in Andong Rural Area 2. Based on the Biochemical Measurements and Nutrient Intakes
    Hye-Sang Lee, Chong-Suk Kwon
    Journal of the Korean Society of Food Science and Nutrition.2010; 39(10): 1459.     CrossRef
  • 6,571 View
  • 68 Download
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Liver Pathology

Nonalcoholic Steatohepatitis
So-Young Jin
Korean J Hepatol 2006;12(3):455-459.
  • 3,622 View
  • 21 Download
Original Article
The Prevalence of Metabolic Syndrome in Patients with Nonalcoholic Fatty Liver Disease
Ki Won Moon, M.D., Joung Muk Leem, M.D., Sang Seok Bae, M.D., Ki Man Lee, M.D., Seok Hyung Kim, M.D.*, Hee Bok Chae, M.D., Seon Mee Park, M.D. and Sei Jin Youn, M.D.
Korean J Hepatol 2004;10(3):197-206.
Background/Aims
Nonalcoholic fatty liver disease (NAFLD) is associated with dyslipidemia, obesity, and insulin resistance, which are the main features of metabolic syndrome. First, we examined the prevalence of metabolic syndrome among patients with NAFLD . We then compared the prevalence of metabolic syndrome in simple steatosis with that in nonalcoholic steatohepatitis (NASH). Finally, we sought to identify clinical factors associated with the stage of liver fibrosis. Methods: From November 2002 to March 2004, we enrolled consecutive 25 patients with NAFLD from patients visiting outpatient clinic. The 17 controls were healthy persons w ho visited our health promotion center. We compared the clinical and biochemical data of the NAFLD group with those of the control group. Using histologic findings, we divided NAFLD into simple steatosis and NASH. We then compared the clinical and biochemical data of the simple steatosis group with those of the NASH group. Results: Fourteen patients (14/25, 56%) had metabolic syndrome in the NAFLD group. There was no difference in the prevalence of metabolic syndrome between the simple steatosis (5/10, 50%) and the NASH group (9/15, 60%). We found significant differences in cardiovascular risk factors between the two groups, but homeostasis model assessment insulin resistance w as the only significantly different factor between the simple steatosis group and the NASH group. In addition, no difference in histological features was found between NASH with metabolic syndrome and without metabolic syndrome. Conclusions: A considerable number of patients with NAFLD had metabolic syndrome. There was a close correlation between NAFLD and metabolic syndrome. We could not find any cardiovascular risk factors that could predict a severe fibrosis. (Korean J Hepatol 2004;10:197-206)
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