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Geum-Ha Kim, M.D., Yun Soo Kim, M.D., Hyun Ok Kim, M.D.,
Kil Hyun Kim, M.D., Young Kul Hung, M.D., Dong Hae Jung, M.D.1, Jeong Ho Kim, M.D.2,
Oh Sang Kwon, M.D., Duck Joo Choi, M.D., Ju Hyun Kim, M.D.
Korean J Hepatol 2009;15(4):510-516. Published online December 31, 2009
Primary hepatic epithelioid hemangioendothelioma is a rare neoplasm of endothelial origin. The clinical manifestations are nonspecific, ranging from complete absence of symptoms to hepatic failure and death. Spontaneous rupture of a hepatic epithelioid hemangioendothelioma is an extremely rare presentation. We present a case of primary hepatic epithelioid hemangioendothelioma in a 65-year-old male patient with alcoholic liver cirrhosis. He was hospitalized due to epigastric pain and multiple liver masses on abdominal ultrasound. Dynamic liver CT imaging revealed multiple peripheral nodular enhanced mass lesions with delayed centripetal enhancement, and the adjacent collection of high-attenuation fluid along the liver capsule. Abdominal tapping revealed blood in the peritoneal cavity. Primary hepatic epithelioid hemangioendothelioma with spontaneous rupture was finally diagnosed based on a histopathologic examination revealing positive immunohistochemical staining for CD34. (Korean J Hepatol 2009;15:510-516)
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Diffuse Hepatic Epithelioid Hemangioendothelioma Developed in a Patient with Hepatitis C Cirrhosis Pedro W. Baron, Thomas Amankonah, Robert F. Cubas, Arputharaj H. Kore, Arvand Elihu, Michael E. de Vera, Mia C. N. Perez Case Reports in Transplantation.2014; 2014: 1. CrossRef
Soung Won Jeong, M.D., Hyun Young Woo, M.D., Chan Ran You, M.D.,
Won Hang Huh, M.D., Si Hyun Bae, M.D., Jong Young Choi, M.D.,
Seung Kew Yoon, M.D., Chan Kwon Jung, M.D.1, Eun Sun Jung, M.D.1
Korean J Hepatol 2008;14(4):525-531. Published online December 31, 2008
Epithelioid hemangioendothelioma is a neoplasm of vascular origin with a low-to-intermediate malignant potential and is one of the rare sarcomas arising from the liver. Its etiology is unknown and its clinical outcome is unpredictable. There is no generally accepted therapeutic strategy because of its rarity and the variable natural course between hemangioma and angiosarcoma. We report a case of a 64-year old woman who underwent hepatic resection due to epithelioid hemangioendothelioma in the right lobe that progressed to extrahepatic metastases of the bone, pleura, and peritoneum 22 months later. However, after resection there was no primary hepatic recurrence. (Korean J Hepatol 2008;14:525-531)
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