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"Peter Konyn"

Editorial

Hepatic neoplasm

The current trends in the health burden of primary liver cancer across the globe
Peter Konyn, Aijaz Ahmed, Donghee Kim
Clin Mol Hepatol 2023;29(2):358-362.
Published online March 14, 2023
DOI: https://doi.org/10.3350/cmh.2023.0092

Citations

Citations to this article as recorded by  Crossref logo
  • Integrative genomic and transcriptomic profiling identifies HSPA5 as a central player in hepatocellular carcinoma pathogenesis
    Taimoor Riaz, Sumbal Rasheed, Muhammad Zubair
    Computational Biology and Chemistry.2026; 120: 108722.     CrossRef
  • Diagnostic Test Accuracy of Contrast‐Enhanced Ultrasound With Sonazoid for Assessment of Focal Liver Lesions: A Systematic Review and Meta‐Analysis
    Yongqing Tang, Shun‐ichi Sasaki, Joshua Hawley, Aurélie Peillon, Anders Sjöström, Adolfo Fuentes‐Alburo, Francois Tranquart
    Journal of Clinical Ultrasound.2025; 53(3): 510.     CrossRef
  • Contemporary awareness of viral hepatitis between 2012 and 2022 among Korean adults
    Donghee Kim, Won Kim, Aijaz Ahmed
    Clinical and Molecular Hepatology.2025; 31(1): e5.     CrossRef
  • Long-term outcomes and risk modifiers of metabolic dysfunction-associated steatotic liver disease between lean and non-lean populations
    Pojsakorn Danpanichkul, Kanokphong Suparan, Vitchapong Prasitsumrit, Aijaz Ahmed, Karn Wijarnpreecha, Donghee Kim
    Clinical and Molecular Hepatology.2025; 31(1): 74.     CrossRef
  • Dual-Functional Micelles for Codelivery of Sorafenib and Dehydrodiisoeugenol in Treatment of Hepatocellular Carcinoma
    Su-Yu Yang, Shu-Tong Li, Tian-Hua Li, De-Jin Ma, Jun-Jie Yu, Yang Liu, Yang Yu, Xue-Tao Li, Juan Zang, Zi-Min Yuan, Liang Kong
    ACS Applied Nano Materials.2025; 8(11): 5355.     CrossRef
  • Global burden of HBV-related liver disease: Primary liver cancer due to chronic HBV infection increased in over one-third of countries globally from 2000 to 2021
    Pojsakorn Danpanichkul, Kwanjit Duangsonk, Vincent L. Chen, Preenapun Saokhieo, Disatorn Dejvajara, Banthoon Sukphutanan, Majd B. Aboona, Chawin Lopimpisuth, Yanfang Pang, Andrew F. Ibrahim, Michael B. Fallon, Daniel Q. Huang, Donghee Kim, Amit G. Singal,
    Hepatology.2025; 82(5): 1274.     CrossRef
  • A Novel Nuclear-Localized Micropeptide, MP60, Promotes Hepatocellular Carcinoma Progression via the Epithelial-Mesenchymal Transition
    Chencheng Li, Xiu Hong, Sarra Setrerrahmane, Xiaoyi Sun, Xue Zhang, Hanmei Xu
    Cancers.2025; 17(17): 2932.     CrossRef
  • MicroRNA-372-3p impairs fatty acid metabolism in hepatocellular carcinoma cells by targeting CPT1A and ACSL4
    Chinnatam Phetkong, Thammachanok Boonto, Pannathon Thamjamrassri, Chaiyaboot Ariyachet, Pisit Tangkijvanich
    BioImpacts.2025; 15: 31075.     CrossRef
  • Social Determinants of Health in Metabolic Dysfunction‐Associated Steatotic Liver Disease and All‐Cause/Cause‐Specific Mortality
    Donghee Kim, Pojsakorn Danpanichkul, Karn Wijarnpreecha, Rohit Loomba, Aijaz Ahmed
    Alimentary Pharmacology & Therapeutics.2025;[Epub]     CrossRef
  • Validation of prognostic models for predicting postsurgical outcomes in intrahepatic cholangiocarcinoma patients using a multicenter cohort
    Dong Hwan Kim, Sang Hyun Choi, Sehee Kim, Woohyung Lee, Hyung-Don Kim, Hyungjin Rhee, Eun-Suk Cho, Suk-Keu Yeom, Sumi Park, Seung Soo Lee, Mi-Suk Park
    International Journal of Surgery.2025; 111(10): 7032.     CrossRef
  • Multidisciplinary comprehensive treatment of massive hepatocellular carcinoma with hemorrhage: A case report and review of literature
    Xian-Shuai Kou, Fan-Fan Li, Yun Meng, Jian-Ming Zhao, Sheng-Fen Liu, Lan Zhang
    World Journal of Gastrointestinal Oncology.2024; 16(5): 2225.     CrossRef
  • Evaluation of different scoring systems for repeating Transarterial Chemoembolization in Egyptian patients with Hepatocellular Carcinoma
    Omkolsoum Alhaddad, Asmaa Gomaa, Merhan El Shamandy, Mohamed Kohla, Ahmed Edrees, Reham Ashour
    Romanian Journal of Internal Medicine.2024; 62(4): 430.     CrossRef
  • Phytochemicals and Their Nanoformulations for Targeting Hepatocellular Carcinoma: Exploring Potential and Targeting Strategies
    Safia Obaidur Rab, R. Roopashree, Farag M. A. Altalbawy, M. Ravi Kumar, Mamata Chahar, Manmeet Singh, Aziz Kubaev, Hassan Thoulfikar A. Alamir, Faraj Mohammed, Abed J. Kadhim, Merwa Alhadrawi
    Cell Biochemistry and Function.2024;[Epub]     CrossRef
  • Modulation of gut microbiota by probiotics to improve the efficacy of immunotherapy in hepatocellular carcinoma
    Ping Chen, Chengchen Yang, Ke Ren, Mingzhi Xu, Chenwei Pan, Xuewei Ye, Lanjuan Li
    Frontiers in Immunology.2024;[Epub]     CrossRef
  • Current epidemiology of chronic liver disease
    Richie Manikat, Aijaz Ahmed, Donghee Kim
    Gastroenterology Report.2023;[Epub]     CrossRef
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Review

Steatotic liver disease

Causes and risk profiles of mortality among individuals with nonalcoholic fatty liver disease
Peter Konyn, Aijaz Ahmed, Donghee Kim
Clin Mol Hepatol 2023;29(Suppl):S43-S57.
Published online November 22, 2022
DOI: https://doi.org/10.3350/cmh.2022.0351
Nonalcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease in the United States and worldwide. Though nonalcoholic fatty liver per se may not be independently associated with an increased risk for all-cause mortality, it is associated with a number of harmful metabolic risk factors, such as type 2 diabetes mellitus, hyperlipidemia, obesity, a sedentary lifestyle, and an unhealthy diet. The fibrosis stage is a predictor of all-cause mortality in NAFLD. Mortality in individuals with NAFLD has been steadily increasing, and the most common cause-specific mortality for NAFLD is cardiovascular disease, followed by extra-hepatic cancer, liver-related mortality, and diabetes. High-risk profiles for mortality in NAFLD include PNPLA3 I148M polymorphism, low thyroid function and hypothyroidism, and sarcopenia. Achieving weight loss through adherence to a high-quality diet and sufficient physical activity is the most important predictor of improvement in NAFLD severity and the benefit of survival. Given the increasing health burden of NAFLD, future studies with more long-term mortality data may demonstrate an independent association between NAFLD and mortality.

Citations

Citations to this article as recorded by  Crossref logo
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    European Journal of Gastroenterology & Hepatology.2026; 38(1): 63.     CrossRef
  • Unveiling the Burden of Steatotic Liver Disease: Mortality Risks by Subtype and Fibrosis Stage in a Nationwide Cohort
    Qi Feng, Pinelopi Manousou, Chioma N. Izzi‐Engbeaya, Rohit Loomba, Mark Thursz, Mark Woodward
    Liver International.2026;[Epub]     CrossRef
  • Secondary Growth Hormone Deficiency That Developed into Cirrhosis after Several Years of Interrupted Growth Hormone Replacement Therapy
    Ayana Sueki, Daisuke Kaya, Shinsaku Nagamatsu, Chisa Yamamoto, Kohei Ohta, Yuya Matsuo, Yuya Nishio, Yusuke Komeda, Shoma Kikukawa, Kyohei Matsuura, Hideki Matsuo, Masakazu Uejima, Kei Moriya
    Internal Medicine.2025; 64(3): 387.     CrossRef
  • Liver Cancer Risk Across Metabolic Dysfunction-Associated Steatotic Liver Disease and/or Alcohol: A Nationwide Study
    Byungyoon Yun, Heejoo Park, Sang Hoon Ahn, Juyeon Oh, Beom Kyung Kim, Jin-Ha Yoon
    American Journal of Gastroenterology.2025; 120(2): 410.     CrossRef
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    Antonio Mirijello, Gabriella Pacilli, Antonio Siena, Antonio Mangiacotti, Maria Maddalena D'Errico, Daria Dilalla, Olga Lamacchia, Andrea Fontana, Massimiliano Copetti, Pamela Piscitelli, Giovanni Targher, Salvatore A. De Cosmo
    Nutrition, Metabolism and Cardiovascular Diseases.2025; 35(1): 103768.     CrossRef
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    Donghee Kim, Brandon J. Perumpail, Pojsakorn Danpanichkul, Karn Wijarnpreecha, Aijaz Ahmed
    Clinical Gastroenterology and Hepatology.2025; 23(4): 665.     CrossRef
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    Alimentary Pharmacology & Therapeutics.2025; 61(2): 400.     CrossRef
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    World Journal of Gastroenterology.2025;[Epub]     CrossRef
  • PNPLA3 is one of the bridges between TM6SF2 E167K variant and MASLD: Correspondence to editorial on “TM6SF2 E167K variant decreases PNPLA3-mediated PUFA transfer to promote hepatic steatosis and injury in MASLD”
    Baokai Sun, Likun Zhuang
    Clinical and Molecular Hepatology.2025; 31(1): e67.     CrossRef
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    Journal of Cachexia, Sarcopenia and Muscle.2025;[Epub]     CrossRef
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    Exploration of Medicine.2025;[Epub]     CrossRef
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    Journal of Drug Delivery Science and Technology.2025; 107: 106802.     CrossRef
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    Nature Reviews Disease Primers.2025;[Epub]     CrossRef
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    Frontiers in Physiology.2025;[Epub]     CrossRef
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    Clinical and Molecular Hepatology.2025; 31(2): 382.     CrossRef
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    BMC Gastroenterology.2025;[Epub]     CrossRef
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