Clinical and Molecular Hepatology (Clin Mol Hepatol, CMH)

Original Article

Molecular classification of hepatocellular carcinoma based on zoned metabolic feature and oncogenic signaling pathway

Tomoko Aoki, Naoshi Nishida, Yutaka Kurebayashi, Kazuko Sakai, Naoto Fujiwara, Masakatsu Tsurusaki, Kohei Hanaoka, Masahiro Morita, Hirokazu Chishina, Masahiro Takita, Satoru Hagiwara, Hiroshi Ida, Kazuomi Ueshima, Yasunori Minami, Atsushi Takebe, Takaaki Murase, Keiko Kamei, Takuya Nakai, Ippei Matsumoto, Kazuto Nishio, Masatoshi Kudo

Clin Mol Hepatol. 2025;31(3):981-1002. Published online March 11, 2025

DOI: https://doi.org/10.3350/cmh.2024.1088

View: 2122 Download: 222

Review

Current evidence and the potential role of proton beam therapy for hepatocellular carcinoma

Sung Uk Lee, Tae Hyun Kim

Clin Mol Hepatol. 2023;29(4):958-968. Published online August 29, 2023

DOI: https://doi.org/10.3350/cmh.2023.0274

View: 5214 Download: 135 Web of Science: 11 Crossref: 10

Original Article

Hepatocellular carcinoma prediction model performance decreases with long-term antiviral therapy in chronic hepatitis B patients

Xiaoning Wu, Xiaoqian Xu, Jialing Zhou, Yameng Sun, Huiguo Ding, Wen Xie, Guofeng Chen, Anlin Ma, HongXin Piao, Bingqiong Wang, Shuyan Chen, Tongtong Meng, Xiaojuan Ou, Hwai-I Yang, Jidong Jia, Yuanyuan Kong, Hong You

Clin Mol Hepatol. 2023;29(3):747-762. Published online May 10, 2023

DOI: https://doi.org/10.3350/cmh.2023.0121

View: 4106 Download: 168 Web of Science: 8 Crossref: 9

Review

Utility of combining PIVKA-II and AFP in the surveillance and monitoring of hepatocellular carcinoma in the Asia-Pacific region

Do Young Kim, Bao Nguyen Toan, Chee-Kiat Tan, Irsan Hasan, Lyana Setiawan, Ming-Lung Yu, Namiki Izumi, Nguyen Nguyen Huyen, Pierce Kah-Hoe Chow, Rosmawati Mohamed, Stephen Lam Chan, Tawesak Tanwandee, Teng-Yu Lee, Thi Thanh Nguyen Hai, Tian Yang, Woo-Chang Lee, Henry Lik Yuen Chan

Clin Mol Hepatol. 2023;29(2):277-292. Published online January 30, 2023

DOI: https://doi.org/10.3350/cmh.2022.0212

View: 11575 Download: 659 Web of Science: 77 Crossref: 80

Crosstalk between tumor-associated macrophages and neighboring cells in hepatocellular carcinoma

Pil Soo Sung

Clin Mol Hepatol. 2022;28(3):333-350. Published online October 19, 2021

DOI: https://doi.org/10.3350/cmh.2021.0308

View: 19451 Download: 396 Web of Science: 32 Crossref: 36

Letter to the Editor

Impact of branched-chain amino acids and frailty on the management of lenvatinib-related fatigue in patients with hepatocellular carcinoma

Shigeo Shimose, Shunji Koya, Takumi Kawaguchi, Keisuke Hirota, Sachiyo Yoshio, Takashi Niizeki, Hiroo Matsuse, Takuji Torimura

Clin Mol Hepatol. 2021;27(4):616-619. Published online September 13, 2021

DOI: https://doi.org/10.3350/cmh.2021.0258

View: 6366 Download: 211 Web of Science: 6 Crossref: 6

Original Article

New next-generation microwave thermosphere ablation for small hepatocellular carcinoma

Hideyuki Tamai, Jumpei Okamura

Clin Mol Hepatol. 2021;27(4):564-574. Published online August 2, 2021

DOI: https://doi.org/10.3350/cmh.2021.0136

View: 6647 Download: 259 Web of Science: 23 Crossref: 21

Editorial

Microwave thermosphere versus radiofrequency ablation for hepatocellular carcinoma: Are we approaching the time to end the debate?

Man-Deuk Kim

Clin Mol Hepatol. 2021;27(4):560-561. Published online September 8, 2021

DOI: https://doi.org/10.3350/cmh.2021.0279

View: 4865 Download: 137 Web of Science: 1 Crossref: 1

Original Article

Serum fibrosis index-based risk score predicts hepatocellular carcinoma in untreated patients with chronic hepatitis B

Lilian Yan Liang, Hye Won Lee, Vincent Wai-Sun Wong, Terry Cheuk-Fung Yip, Yee-Kit Tse, Vicki Wing-Ki Hui, Grace Chung-Yan Lui, Henry Lik-Yuen Chan, Grace Lai-Hung Wong

Clin Mol Hepatol. 2021;27(3):499-509. Published online February 26, 2021

DOI: https://doi.org/10.3350/cmh.2020.0333

View: 6355 Download: 143 Web of Science: 16 Crossref: 16

Editorial

Risk of hepatocellular carcinoma in untreated patients with chronic hepatitis B: Independent of HBeAg status?

Ho Soo Chun, Minjong Lee

Clin Mol Hepatol. 2021;27(3):448-450. Published online June 23, 2021

DOI: https://doi.org/10.3350/cmh.2021.0130

View: 5326 Download: 130 Web of Science: 2 Crossref: 1

Review

Entecavir versus tenofovir in patients with chronic hepatitis B: Enemies or partners in the prevention of hepatocellular carcinoma

Sung Won Lee, Jonggi Choi, Seung Up Kim, Young-Suk Lim

Clin Mol Hepatol. 2021;27(3):402-412. Published online June 23, 2021

DOI: https://doi.org/10.3350/cmh.2021.0179

View: 7780 Download: 276 Web of Science: 37 Crossref: 35

Original Article

Significant down-regulation of growth hormone receptor expression revealed as a new unfavorable prognostic factor in hepatitis C virus-related hepatocellular carcinoma

Ching-Chih Lin, Ta-Wei Liu, Ming-Lun Yeh, Yi-Shan Tsai, Pei-Chien Tsai, Chung-Feng Huang, Jee-Fu Huang, Wan-Long Chuang, Chia-Yen Dai, Ming-Lung Yu

Clin Mol Hepatol. 2021;27(2):313-328. Published online December 14, 2020

DOI: https://doi.org/10.3350/cmh.2020.0247

View: 12332 Download: 166 Web of Science: 11 Crossref: 9

Negligible risks of hepatocellular carcinoma during biomarker-defined immune-tolerant phase for patients with chronic hepatitis B

Mi Young Jeon, Beom Kyung Kim, Jae Seung Lee, Hye Won Lee, Jun Yong Park, Do Young Kim, Sang Hoon Ahn, Kwang-Hyub Han, Seung Up Kim

Clin Mol Hepatol. 2021;27(2):295-304. Published online December 3, 2020

DOI: https://doi.org/10.3350/cmh.2020.0216

View: 6864 Download: 219 Web of Science: 24 Crossref: 26

Review

Optimizing the management of intermediate-stage hepatocellular carcinoma: Current trends and prospects

Takuji Torimura, Hideki Iwamoto

Clin Mol Hepatol. 2021;27(2):236-245. Published online December 3, 2020

DOI: https://doi.org/10.3350/cmh.2020.0204

View: 11299 Download: 408 Web of Science: 47 Crossref: 46

Original Article

Obesity and the risk of primary liver cancer: A systematic review and meta-analysis

Won Sohn, Hyun Woong Lee, Sangheun Lee, Jin Hong Lim, Min Woo Lee, Chan Hyuk Park, Seung Kew Yoon

Clin Mol Hepatol. 2021;27(1):157-174. Published online November 26, 2020

DOI: https://doi.org/10.3350/cmh.2020.0176

View: 13115 Download: 465 Web of Science: 108 Crossref: 112

Radiation-induced abscopal effect and its enhancement by programmed cell death 1 blockade in the hepatocellular carcinoma: A murine model study

Gyu Sang Yoo, Won-Gyun Ahn, Shin-Yeong Kim, Wonseok Kang, Changhoon Choi, Hee Chul Park

Clin Mol Hepatol. 2021;27(1):144-156. Published online December 7, 2020

DOI: https://doi.org/10.3350/cmh.2020.0095

View: 9394 Download: 320 Web of Science: 26 Crossref: 28

Editorial

Old hepatitis B virus never dies: It just hides itself within the host genome

Jeong-Hoon Lee

Clin Mol Hepatol. 2021;27(1):107-109. Published online December 23, 2020

DOI: https://doi.org/10.3350/cmh.2020.0324

View: 4845 Download: 120 Web of Science: 4 Crossref: 3

Exploring the mythical abscopal effect: Radiation and programmed cell death protein 1 (PD-1) blockade for hepatocellular carcinoma

Jun Won Kim, Ik Jae Lee

Clin Mol Hepatol. 2021;27(1):103-106. Published online December 14, 2020

DOI: https://doi.org/10.3350/cmh.2020.0297

View: 5166 Download: 106 Web of Science: 1 Crossref: 1

Metabolic disease as a risk of hepatocellular carcinoma

Naoshi Nishida

Clin Mol Hepatol. 2021;27(1):87-90. Published online December 3, 2020

DOI: https://doi.org/10.3350/cmh.2020.0302

View: 6233 Download: 121 Web of Science: 17 Crossref: 18

Special topic: Alcoholic liver diseases The 14th International Symposium on Alcoholic Liver and Pancreatic Diseases and Cirrhosis (ISALPDC)

Hepatic Hippo signaling inhibits development of hepatocellular carcinoma

Yuchen Liu, Xiaohui Wang, Yingzi Yang

Clin Mol Hepatol. 2020;26(4):742-750. Published online September 28, 2020

DOI: https://doi.org/10.3350/cmh.2020.0178

View: 10021 Download: 232 Web of Science: 49 Crossref: 45

Letter to the Editor

Phosphoinositide 3-kinase inhibitors are effective therapeutic drugs for the treatment of hepatocellular carcinoma?

Jeong Su Park, Soo Han Bae

Clin Mol Hepatol. 2020;26(4):577-578. Published online September 17, 2020

DOI: https://doi.org/10.3350/cmh.2020.0143

View: 4828 Download: 68 Web of Science: 1 Crossref: 1

Original Article

Inhibition of PI3K/Akt signaling suppresses epithelial-to-mesenchymal transition in hepatocellular carcinoma through the Snail/GSK-3/beta-catenin pathway

Seulki Lee, Eun Ji Choi, Eun Ju Cho, Yun Bin Lee, Jeong-Hoon Lee, Su Jong Yu, Jung-Hwan Yoon, Yoon Jun Kim

Clin Mol Hepatol. 2020;26(4):529-539. Published online August 24, 2020

DOI: https://doi.org/10.3350/cmh.2019.0056n

View: 10672 Download: 274 Web of Science: 42 Crossref: 41

Substantial risk of recurrence even after 5 recurrence-free years in early-stage hepatocellular carcinoma patients

Jihye Kim, Wonseok Kang, Dong Hyun Sinn, Geum-Youn Gwak, Yong-Han Paik, Moon Seok Choi, Joon Hyeok Lee, Kwang Cheol Koh, Seung Woon Paik

Clin Mol Hepatol. 2020;26(4):516-528. Published online September 11, 2020

DOI: https://doi.org/10.3350/cmh.2020.0016

View: 7981 Download: 219 Web of Science: 56 Crossref: 51

Stereotactic body radiation therapy for small (≤5 cm) hepatocellular carcinoma not amenable to curative treatment: Results of a single-arm, phase II clinical trial

Sang Min Yoon, So Yeon Kim, Young-Suk Lim, Kang Mo Kim, Ju Hyun Shim, Danbi Lee, Jihyun An, Jinhong Jung, Jong Hoon Kim, Han Chu Lee

Clin Mol Hepatol. 2020;26(4):506-515. Published online July 10, 2020

DOI: https://doi.org/10.3350/cmh.2020.0038

View: 8576 Download: 217 Web of Science: 59 Crossref: 60

Editorial

Long-term prognosis and management of hepatocellular carcinoma after curative treatment

Naoshi Nishida

Clin Mol Hepatol. 2020;26(4):480-483. Published online September 21, 2020

DOI: https://doi.org/10.3350/cmh.2020.0208

View: 6548 Download: 105 Web of Science: 14 Crossref: 13

Sarcopenia and blood myokine levels as prognostic biomarkers in patients with liver cirrhosis or hepatocellular carcinoma

Sooyeon Oh, Jooho Lee

Clin Mol Hepatol. 2020;26(4):476-479. Published online October 1, 2020

DOI: https://doi.org/10.3350/cmh.2020.0192

View: 6369 Download: 168 Web of Science: 12 Crossref: 11

Original Article

Low-level viremia and cirrhotic complications in patients with chronic hepatitis B according to adherence to entecavir

Seung Bum Lee, Joonho Jeong, Jae Ho Park, Seok Won Jung, In Du Jeong, Sung-Jo Bang, Jung Woo Shin, Bo Ryung Park, Eun Ji Park, Neung Hwa Park

Clin Mol Hepatol. 2020;26(3):364-375. Published online May 29, 2020

DOI: https://doi.org/10.3350/cmh.2020.0012

View: 7613 Download: 302 Web of Science: 30 Crossref: 30

Comparison of LI-RADS 2018 and KLCA-NCC 2018 for noninvasive diagnosis of hepatocellular carcinoma using magnetic resonance imaging

Sunyoung Lee, Seung-seob Kim, Dong ryul Chang, Hyerim Kim, Myeong-Jin Kim

Clin Mol Hepatol. 2020;26(3):340-351. Published online June 4, 2020

DOI: https://doi.org/10.3350/cmh.2020.0004

View: 10330 Download: 230 Web of Science: 47 Crossref: 50

Editorial

Diagnosis of hepatocellular carcinoma: Which MRI contrast agent? Which diagnostic criteria?

So Yeon Kim

Clin Mol Hepatol. 2020;26(3):309-311. Published online June 15, 2020

DOI: https://doi.org/10.3350/cmh.2020.0061

View: 6059 Download: 106 Web of Science: 5 Crossref: 5

Optimal sequence of systemic therapy after sorafenib failure in patients with hepatocellular carcinoma

Sojung Han, Do Young Kim

Clin Mol Hepatol. 2020;26(3):305-308. Published online July 1, 2020

DOI: https://doi.org/10.3350/cmh.2020.0096

View: 5410 Download: 117 Web of Science: 5 Crossref: 5

1 | 2 | 3 |

Viewed By 12651	Epidemiology of metabolic dysfunction-associated steatotic liver disease
Viewed By 7658	Radiogenomics of intrahepatic cholangiocarcinoma predicts immunochemotherapy response and identifies therapeutic target
Viewed By 7155	MAFLD: How is it different from NAFLD?
Viewed By 5707	Assessing the performance of ChatGPT in answering questions regarding cirrhosis and hepatocellular carcinoma
Viewed By 5642	Hepatocellular carcinoma: updates on epidemiology, surveillance, diagnosis and treatment

Cited By 369	Assessing the performance of ChatGPT in answering questions regarding cirrhosis and hepatocellular carcinoma
Cited By 354	Global incidence and prevalence of nonalcoholic fatty liver disease
Cited By 232	MAFLD: How is it different from NAFLD?
Cited By 122	Non-alcoholic fatty liver disease: Definition and subtypes
Cited By 116	Pathogenesis and treatment of non-alcoholic steatohepatitis and its fibrosis

Search