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| ORIGINAL ARTICLES |
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CMH
2000 December;6:495-504.
Published online 2000 January 01.
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| Copyright © 2000 The Korean Association for the Study of the Liver |
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| Clinical Characteristics of Female Hepatocellular Carcinoma |
| Sung Moon Jung, Yeon Kyeong Kim, Jin Ok Lee, Sook-Hyang Jung, Chul Ju Han, You Cheoul Kim,
Chang-Min Kim, Jhin Oh Lee, Jin A Cho1 , Soo Yong Choi1 |
| Department of Internal Medicine, Laboratory of Clinical Research1 Korea Cancer Center Hospital, Seoul, Korea |
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| ABSTRACT |
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| Background/Aims: The incidence of hepatocellular carcinoma has been universally lower in female than in male. The aims of our study are to define whether there are any difference between female and male patients with hepatocellular carcinoma in terms of clinical characteristics and results of treatment. Methods: Retrospective analyses of medical history, physical findings, laboratory results, etiological factors, characteristics of tumor, and therapeutic results were performed in 80 female patients with hepatocellular carcinoma compared to 160 male patients. Results: Asymptomatic presentation and family history of liver disease were found more frequently in female patients than in male patients. A history of smoking and alcohol drinking were found less frequently in female patients than in male patients. The detection rate of spider angioma was significantly lower in female patients than in male patients. There was no difference in laboratory results, characteristics of tumor, and therapeutic results between female and male patients. Conclusions: Environmental factors such as smoking and alcohol drinking could contribute the sexual difference of hepatocarcinogenesis. However, clinical characteristics at the time of diagnosis and therapeutic results were not significantly different between female and male patients with hepatocellular carcinoma. |
| Keywords: Neoplasm/Liver/Hepatocellular carcinoma, Female |
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