Letter regarding “Is liver biopsy essential to identifying the immune tolerant phase of chronic hepatitis B?”

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Clin Mol Hepatol. 2023;29(3):812-812
Publication date (electronic) : 2023 May 8
doi : https://doi.org/10.3350/cmh.2023.0132
Division of Pediatric Gastroenterology, Department of Pediatrics, Selçuk University Faculty of Medicine, Konya, Türkiye
Corresponding author : Halil Haldun Emiroglu Division of Pediatric Gastroenterology, Department of Pediatrics, Selçuk University Faculty of Medicine, Selcuklu/Konya 42131, Türkiye Tel: +90 (332) 241 21 83, Fax: +90 (332) 241 21 84, E-mail: haldunemiroglu@gmail.com
Editor: Seung Up Kim, Yonsei University College of Medicine, Korea
Received 2023 March 30; Revised 2023 April 6; Accepted 2023 April 7.

Dear Editor,

I read with great interest the editorial paper by Oh and Sinn [1] entitled “Is liver biopsy mandatory to identify immunetolerant phase of chronic hepatitis B?” published online ahead of print. In their paper, Oh and Sinn [1] suggested that the status of patients presumed to be in the immune-tolerant phase without histological information should be carefully evaluated. I would like to draw attention to the following printing error related to the normal serum alanine aminotransferase (ALT) levels according to the American Association for the Study of Liver Disease (AASLD) guidelines. The recommended normal serum ALT level for males was incorrectly written as “<33 U/L” in both the text and Table 1. However, according to the AASLD 2018 hepatitis B guidance [2], the upper limit of normal for ALT in males is 35 U/L.

I believe that correcting this printing error will prevent any possible confusion in daily practice guiding management decisions.

Notes

Conflicts of Interest

The authors have no conflicts to disclose.

Abbreviations

ALT

alanine aminotransferase

AASLD

American Association for the Study of Liver Disease

References

1. Oh JH, Sinn DH. Is liver biopsy essential to identifying the immune tolerant phase of chronic hepatitis B? Clin Mol Hepatol 2023;29:367–370.
2. Terrault NA, Lok ASF, McMahon BJ, Chang KM, Hwang JP, Jonas MM, et al. Update on prevention, diagnosis, and treatment of chronic hepatitis B: AASLD 2018 hepatitis B guidance. Hepatology 2018;67:1560–1599.

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